Clinical trials: sponsored by Alcon Research
Contact Lens Disinfecting Solutions
Comparison of Two Multi-Purpose Solution and Lens Material Combinations on Corneal Barrier Function
The purpose of this study is to measure the relative "barrier" function of the top layer of the cornea (called the epithelium), or the degree to which the cornea can prevent the penetration of the colored dye sodium fluorescein…
- Trial name
- NCT00560898
- Testing
- ProClear Lens Material soaked in ReNu Multiplus Multipurpose Solution, Acuvue Advance Lens Material soaked in ReNu Multiplus Multipurpose Solution, Acuvue Advance Lens Material soaked in Optifree RepleniSH Multipurpose Solution
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Open-Angle Glaucoma, Ocular Hypertension
A Phase II Study of AL-37807 to Treat Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to determine whether AL-37807 is safe and effective in treating patients with open-angle glaucoma or ocular hypertension
- Trial name
- NCT00372931
- Testing
- AL-37807
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Alcon Research
Contact Lens Care
Corneal Barrier Function With Multi-Purpose Solutions
The purpose of this study is to evaluate the effect on epithelial barrier function of three emarketed multi-purpose solution applied to the human eye with hydrogel lenses as during normal regimen use.
- Trial name
- NCT00407238
- Testing
- Multi-purpose solutions (polyquaternium-1 and PHMB)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Corneal Epithelial Disruption, Corneal Staining
Evaluation of Corneal Staining With Various Contact Lens/Solution Combinations
The purpose of this study is to quantify the amount of corneal staining observed with various marketed contact lens/multipurpose solution combinations.
- Trial name
- NCT00381446
- Testing
- Marketed contact lens care products
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Andrasko, Gary, OD, LLC
Glaucoma, Intraocular Pressure
IOP Reduction After Anecortave Acetate Injection in Glaucoma Patients
Introduction: Ocular administration of glucocorticoids is a common and effective treatment for several ocular diseases. However it is often complicated with the elevation of intraocular pressure (IOP).
- Trial name
- NCT00533962
- Testing
- Anterior Juxtascleral Depot of Anecortave Acetate
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Eye Injuries
Treatment of Radiation Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg)
Radiation retinopathy is a disease of the retina. It occurs in people who have received or been exposed to radiation near the eyes. The blood vessels are abnormal and may grow which lead to scarring and a loss of central vision.
- Trial name
- NCT00211367
- Testing
- Anecortave Acetate
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Diabetic Retinopathy
Treatment of Diabetic Retinopathy With Open-Label Anecortave Acetate Sterile Suspension (15 mg)
The purpose of this study is to provide compassionate use of anecortave acetate sterile suspension of 15 mg for a series of five patients as a means to control diabetic retinopathy.
- Trial name
- NCT00211406
- Testing
- Anecortave Acetate Sterile Suspension (15 mg)
- Where
- United States
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Age-Related Macular Degenerations., Subfoveal Neovascularization.
Treatment of Conditions With Open Label-Anecortave Acetate Sterile Suspension ( 15mg.) Where Lesions do Not Meet Acceptable Criteria for Standard Care.
A compassionate method of treatment is offered to patients where lesions do not meet acceptable criteria for standard therapy. Visudyne (Photodynamic Therapy) and laser photocoagulation treatment (a treatment using heat from a…
- Trial name
- NCT00211484
- Testing
- Anecortave Acetate
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Severe Diabetic Retinopathy, Central Retinal Vein Occlusion
Treatment of Rubeosis Iridis With Open-Label Anecortave Acetate Sterile Suspension ( 15 mg.).
To provide use of Anecortave Acetate Sterile Suspension of 15mg for a series of five patients with rubeosis iridis. Rubeosis iridis refers to neovascularization of the iris.
- Conditions
- Severe Diabetic Retinopathy, Central Retinal Vein Occlusion, Chronic Inflammation, Infectious Diseases
- Trial name
- NCT00211471
- Testing
- anecortave acetate
- Where
- United States
- Sponsor
- Manhattan Eye, Ear & Throat Hospital
Ametropia
Contact Lens Wettability
The purpose of this study is to compare the wettability of contact lenses disinfected with three marketed contact lens care solutions.
- Trial name
- NCT00349063
- Testing
- soft contact lens, Soft contact lens multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Waterloo
Myopia
Effects of Contact Lens Care Regimens on the Corneal Epithelium
The purpose of this study is to compare the performance of two different contact lens care solutions, specifically their affects on the front surface of the eye.
- Trial name
- NCT00349882
- Testing
- soft contact lens, Marketed multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Open Angle Glaucoma, Ocular Hypertension
Additivity Study: Additive Effect on Eye Pressure of Azopt and Alphagan P to Travatan
The purpose of this study is to compare the additive effect on eye pressure of Azopt and Alphagan P to Travatan.
- Conditions
- Open Angle Glaucoma, Ocular Hypertension, Pseudoexfoliation Syndrome
- Trial name
- NCT00121147
- Testing
- Travatan, Azopt, Alphagan P
- Where
- 21 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hermann Eye Center