Clinical trials: sponsored by Peking University First Hospital
Non-squamous Non-Small Cell Lung Cancer
Apatinib in Advanced Non-squamous，NSCLC
To explore the efficacy and safety of apatinib in non-squamous non-small cell lung cancer in the real-world.
- Trial name
- NCT03376191
- Testing
- apatinib
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jian Fang
Myelodysplastic Syndrome, Chemotherapy
Effect of Chemotherapy vs No Chemotherapy Pre-transplant to MDS Undergoing Allo-HSCT
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) appears to be an efficient tool to cure refractory anemia with excess blasts-1 (RAEB-1), refractory anemia with excess blasts-2 (RAEB-2) and acute myeloid leukemia…
- Trial name
- NCT02850822
- Testing
- Demethylation drug, Chemotherapy regimen
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Acute Myeloid Leukemia
Hematopoietic Stem Cell Microtransplantation for in AML
The purpose of this study is to evaluate the efficacy of hematopoietic stem cell microtransplantation for in acute myeloid leukemia (AML)patients who can not receive hematopoietic stem cell transplantation (HSCT).
- Trial name
- NCT02676856
- Testing
- hematopoietic stem cell microtransplantation-long-term, hematopoietic stem cell microtransplantation-short-term, Conditioning for CR group
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Blood Pressure
Effect of Cemented Implantation in Shoulder Replacement on Blood Pressure
To clarify the downward trend of blood pressure affected by bone cement implantation during shoulder replacement operations.
- Trial name
- NCT03364062
- Testing
- cemented shoulder replacement
- Volunteers
- 350 people
- Sponsor
- Peking University People's Hospital
Epilepsy Idiopathic, Clinical Disease and/or Syndrome
Omics-based Precision Medicine of Epilepsy
Epilepsy is a major disease of the nervous system (WHO, 2015), as well as the second most common neural disease. It has been recorded that there have been 65 million epilepsy patients all over the world, more than 10 million in…
- Conditions
- Epilepsy Idiopathic, Clinical Disease and/or Syndrome, Gene Mutation
- Trial name
- NCT03358459
- Testing
- non
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Fudan University
Pancreatitis, Acute, Hypertriglyceridemia
Intravenous Administration of Insulin and Plasma Exchange on Triglyceride Levels in Early Stage of Hypertriglyceridemia-induced Pancreatitis
To investigate an economical and effective way to reduce the level of serum triglyceride in patients with hypertriglyceridemia-induced acute pancreatitis.
- Trial name
- NCT03342807
- Testing
- Insulin, Aphesis
- Volunteers
- 220 people
- Sponsor
- Peking Union Medical College Hospital
Osteoporosis
Percutaneous Vertebroplasty Versus Conservative Treatment in GIOPVCF
Based on the case reports and other literature, the investigators hypothesize that using PVP for treating GIOPVCF is associated with increased risk of vertebral refractures and does not provide further benefits compared to…
- Trial name
- NCT03330340
- Testing
- Percutaneous Vertebroplasty
- Volunteers
- 106 people
- Sponsor
- Peking University First Hospital
Chronic Hepatitis B
A Nation-wide Hospital-based Hepatitis B Registry:China Registry of Hepatitis B
CR-HepB registry started in June 30,2012 to collect HBV cases from general hospitals or specialized hospitals for infectious diseases in mainland China.
- Trial name
- NCT03108794
- Where
- 45 sites in China
- Volunteers
- 200,000 people
- Sponsor
- Beijing Friendship Hospital
Lymphoma
China Lymphoma Patient Registry Study
Lymphoma is the most common hematologic tumor. It is derived from lymphoid tissue, including Hodgkin's lymphoma(HL) and non Hodgkin's lymphoma(NHL).
- Trial name
- CLAP (NCT03313271)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Jun Zhu
Autologous Hematopoietic Stem Cell Transplantation, Diffuse Large B-cell Lymphoma
BUCY+VP-16 vs BUCY Conditioning Regimen for DLBCL Undergoing Auto-HSCT
The purpose of this study is to evaluate the safety and efficacy of BUCY+VP-16 and BUCY myeloablative conditioning regimens in diffuse large B-cell lymphoma undergoing autologous hematopoietic stem cell transplantation.
- Conditions
- Autologous Hematopoietic Stem Cell Transplantation, Diffuse Large B-cell Lymphoma, Conditioning
- Trial name
- NCT03229616
- Testing
- Busulfan (BU), Cyclophosphamide (CY), Etoposide (VP-16)
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Depressive Disorder
Multi-Dimensional Diagnosis,Individualized Therapy,and Management Technique for Major Depressive Disorder:Based on Clinical and Pathological Characteristics
Major Depressive Disorder is one of the most common mental diseases,which increases health-care costs and the financial burden to families and societies.
- Trial name
- STEP-MDD (NCT03219008)
- Testing
- Fluoxetine, fluoxetine + cognitive-behavioral treatment（CBT）, fluoxetine + Amfebutamone
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Shanghai Mental Health Center
Upper Tract Urothelial Carcinoma, Bladder Recurrence
Prophylactic Intravesical Chemotherapy to Prevent Bladder Recurrence After Diagnostic Ureteroscopy for Primary Upper Tract Urothelial Carcinoma Patients
This clinical trial is designed to evaluate the efficacy of single immediate intravesical chemotherapy instillation in the prevention of bladder recurrence after diagnostic ureteroscopy for upper tract urothelial carcinoma (UTUC)…
- Trial name
- NCT02740426
- Testing
- Pirarubicin
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Gastric Cancer
Robotic Versus Laparoscopic Distal Gastrectomy With D2 Lymphadenectomy for Locally Advanced Gastric Cancer
This study is an investigator-initiated, randomized, controlled, parallel group, and non-inferiority trial comparing robot-assisted gastrectomy with D2 nodal dissection for locally advanced gastric cancer patients with…
- Trial name
- NCT03273920
- Testing
- Robotic distal gastrectomy with D2 nodal dissection, Laparoscopic distal gastrectomy with D2 nodal dissection
- Where
- 14 sites in China
- Volunteers
- 1,110 people
- Sponsor
- Southwest Hospital, China
Growth Hormone Deficiency
Pegylated Somatropin (PEG Somatropin) in the Treatment of Children With Growth Hormone Deficiency
To Evaluate the safety and efficacy of PEG Somatropin in the treatment of children with growth hormone deficiency, as well as to study the dosage of PEG Somatropin.
- Trial name
- NCT03249480
- Testing
- PEG-somatropin
- Where
- 28 sites in China
- Volunteers
- 900 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Recurrence, Metastasis
Lymph Node Dissection in High-risk UTUC(Upper Tract Urothelial Carcinoma)
This clinical trial is designed to evaluate the role of lymph node dissection in the prevention of recurrence and metastasis after radical nephroureterectomy for high-risk primary upper tract urothelial carcinoma (UTUC) patients.
- Conditions
- Recurrence, Metastasis, Upper Tract Urothelial Carcinoma, Lymph Node Dissection
- Trial name
- UTUC (NCT03230201)
- Testing
- Lymph node dissection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Peking University First Hospital
Chronic Obstructive Pulmonary Disease
Exhaled Breathing Condensate (EBC) Features and Lung Function Decline in Chinese Adults
Chronic obstructive lung disease (COPD) is a worldwide leading and still increasing cause of chronic morbidity and mortality. The important issue of COPD is its delayed diagnosis.
- Trial name
- NCT02037828
- Where
- China
- Volunteers
- 2,440 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Crohn Disease
Effectiveness of Rifaximin on Preventing Postoperative Recurrence in Crohn's Disease
Some studies have shown that rifaximin is effective in the management of Crohn's Disease. Meanwhile, its adverse effect is tolerable. But no study has been conducted to assess its effect on preventing postoperative recurrence.
- Trial name
- NCT03185624
- Testing
- Rifaximin
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Labor Pain, Analgesia, Obstetrical
Individualized Timing of Analgesia and Effectiveness of Labor Analgesia
Neuraxial analgesia is the gold standard to relieve labor pain. A recent "Practice guidelines for obstetric anesthesia" suggests that neuraxial analgesia should be provided in the early stage of labor (cervical dilation < 5 cm)…
- Conditions
- Labor Pain, Analgesia, Obstetrical, Early Medical Intervention
- Trial name
- NCT02920489
- Testing
- Individualized epidural analgesia, Routine epidural analgesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Peking University First Hospital
Advanced Maternal Age Pregnancy, High Risk Pregnancy
University Hospital Advanced Age Pregnant Cohort
The University Hospital Advanced Age Pregnant (UNIHOPE) Cohort is the major part of the National Key Research and Development Program on Reproductive Health \& Major Birth Defects Control and Prevention Project, which is funded…
- Conditions
- Advanced Maternal Age Pregnancy, High Risk Pregnancy, Perinatal Death, Maternal Death
- Trial name
- UNIHOPE (NCT03220750)
- Where
- 9 sites in China
- Volunteers
- 22,000 people, healthy volunteers welcome
- Sponsor
- Peking University
Stage III Non-small-Cell Lung Cancer
Recombinant Human Endostatin Continued Pumping Into Vein Combining With CCRT in Unresectable Stage III NSCLC
Resistance of hypoxic tumor cells to radiation is a significant reason of failure in the local control of tumors, especially the squamous cell carcinomas.
- Trial name
- NCT01733589
- Testing
- Recombinant human endostatin, Etoposide (50mg/m2) IV (in the vein) on day 1 to day 5 of a 28-day cycle for 2 cycles, cisplatinum (50mg/m2) IV (in the vein) on day 1 and day 8 of a 28-day cycle for 2 cycles
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Zhejiang Cancer Hospital
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