Clinical trials: sponsored by Icahn School of Medicine at Mount Sinai
Cardiac Arrest
Non Invasive Neuromonitoring After Cardiac Arrest
Cardiac Arrest is among the leading causes of death, with survival still well under 50% and the majority of the survivors suffering from moderate to severe neurologic deficits. The human, social and economic costs are staggering.
- Trial name
- NINCA (NCT02575196)
- Testing
- Non-invasive cerebral flow monitoring
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronotropic Incompetence
The Effect of Blended Sensor Efficiency on Relieving the Heart's Inability to Increase Its Rate During Exercise
The goal of this trial is to test the effect/benefit of a FDA approved blended pacemaker sensor which responds only by comparing physical activity, heart rate, and breathing rate; compared to the accelerometer pacemaker sensor…
- Trial name
- ABSOLVE CI (NCT01619800)
- Testing
- Blended Sensor Optimization (BSO), Accelerometer Alone (AA)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Vivek Reddy
Ovarian Cancer
Contrast-Enhanced Ultrasonography in Diagnosing Early-Stage Ovarian Cancer in Patients With an Adnexal Mass Undergoing Surgery to Remove the Ovary
RATIONALE: New diagnostic procedures, such as contrast-enhanced ultrasonography, may be an effective method of finding ovarian cancer.
- Trial name
- NCT00626873
- Testing
- Definity, medical chart review
- Where
- 3 sites in United States
- Volunteers
- 67 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV-associated Co-morbidities
Vitamin D Supplements for HIV-positive Patients on cART
The ability of vitamin D to modulate the immune system and strengthen bones may mitigate the adverse medication consequences of HIV/AIDS, but little is known about either the health benefits of vitamin D supplements, or about the…
- Trial name
- NCT01295034
- Testing
- conventional vitamin D treatment, tiered/titrated vitamin D dosing
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Andrea Branch
Vitamin D Deficiency, Metabolic Syndrome
Bioavailability and Biological Effects of Vitamin D2 Contained in Mushroom
The purpose of this study is to compare the safety and efficacy of two different amounts of vitamin D2 (600 or 4000 International Units/day) provided by mushrooms added to one of the daily meals versus same doses of vitamin D3…
- Conditions
- Vitamin D Deficiency, Metabolic Syndrome, Prediabetes
- Trial name
- NCT01488734
- Testing
- Mushroom with 600 IU vitamin D2, Mushroom with 4000 IU Vitamin D2, 600 IU Vitamin D3 and untreated mushroom
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Atopic Dermatitis
Treatment of Atopic Dermatitis With Different Orders of Application of Locoid Lotion and Hylatopic Plus Cream
The purpose of this study is to evaluate the safety and tolerability, as well as effectiveness, with regards to the order of application for Locoid Lipocream and Hylatopic Plus cream in patients with atopic dermatitis (AD), which…
- Trial name
- NCT02153762
- Testing
- Locoid Lipocream, Hylatopic Plus
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hepatitis C
Biomarkers of Liver Fibrosis
Chronic liver injury leads to the accumulation of proteins in the liver that form dense scars. Liver scar formation is typically a slow process that leads to major organ damage and loss of function over the course of many years.
- Trial name
- NCT02438917
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Brain Function, Healthy Adults
The Effects of Ondansetron on Brain Function
This project investigates the effects of a single dose of ondansetron on brain function in healthy adults. The investigators hypothesize that there will be a dose-dependent reduction in activation of the insula and somatosensory…
- Trial name
- NCT02460341
- Testing
- ondansetron
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Hematopoietic Stem Cell Transplantation, Breast Cancer
Treating Cancer-Related Fatigue Through Systematic Light Exposure
Cancer related fatigue (CRF) - a persistent sense of exhaustion related to cancer or cancer treatment - can severely interfere with activities of daily living, and has even been reported to be a factor in patient requests for…
- Conditions
- Hematopoietic Stem Cell Transplantation, Breast Cancer, Fatigue, Mild Cognitive Impairment
- Trial name
- NCT01873794
- Testing
- Bright white light, Dim red light
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Depression
Prolonging Remission in Depressed Elderly (PRIDE)
This study will determine whether medications alone or medications and electroconvulsive therapy (ECT) work best to prevent depressive relapse and to improve quality of life for older people with severe mood disorders.
- Trial name
- PRIDE (NCT01028508)
- Testing
- lithium and Venlafaxine, ECT
- Where
- 10 sites in United States
- Volunteers
- 247 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Fibromyalgia
L-Tyrosine Supplementation in Patients With Fibromyalgia
Patients in the study, who have a diagnosis of fibromyalgia, will be randomly assigned to take the amino acid L-tyrosine or placebo (blank pill) for 3 weeks.
- Trial name
- NCT01219049
- Testing
- Tyrosine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cancer of the Pharynx, Cancer of the Larynx
Erlotinib, Celecoxib and Reirradiation for Recurrent Head and Neck Cancer
There is no optimal treatment for patients with recurrent head and neck cancer after previous radiation. Chemotherapy alone is not curative and patients survive an average of only 6 to 10 months.
- Conditions
- Cancer of the Pharynx, Cancer of the Larynx, Cancer of the Neck, Paranasal Sinus Neoplasms
- Trial name
- NCT00970502
- Testing
- erlotinib + celecoxib
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Johnny Kao
Major Depressive Disorder
Cysteamine Therapy for Major Depressive Disorder
The purpose of this study is to determine whether cysteamine bitartrate, an FDA-approved drug for a non-psychiatric condition, is safe and effective for the treatment of major depression.
- Trial name
- NCT00715559
- Testing
- cysteamine bitartrate
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Major Depressive Disorder
MRI Studies of Emotion in Depression
The purpose of this study is to research the effects of ketamine on brain function in patients with Major Depressive Disorder (MDD).
- Trial name
- NCT02429011
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Attention Deficit Disorder With Hyperactivity
Psychosocial Treatment for Attention Deficit Hyperactivity Disorder in Adults
This study will determine the effectiveness of group cognitive-behavioral therapy as compared to a problem-solving social support group in treating problems of time management, organization, and planning in adults with attention…
- Trial name
- NCT00278473
- Testing
- Meta-Cognitive Therapy, Supportive Therapy
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
ADHD
Neurobiological Basis of Response to Vayarin in Adults With ADHD: an fMRI Study of Brain Activation Pre and Post Treatment
The objective of this research is to use functional magnetic resonance imaging (fMRI) with a neuropsychological task to test the prefrontal mechanism of action of the medical food Vayarin.
- Trial name
- VAYA-fMRI (NCT02473419)
- Testing
- Vayarin
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Competency-Based Education
Rapid Assessment of Trainee Endoscopy Skills (RATES) Study
The establishment of a number of training programs in therapeutic endoscopy, standardization of the performance of endoscopic ultrasound (EUS) and endoscopy retrograde cholangiopancreatography (ERCP) and definition of competence…
- Trial name
- RATES (NCT02247115)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder
A Multi-site Double-blind Placebo-controlled Trial of Memantine Versus Placebo in Children With Autism (MEM)
This study will attempt to study the effect of memantine, on memory, and motor praxis/expressive language skills in children with autism.
- Trial name
- NCT01372449
- Testing
- Memantine
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Evdokia Anagnostou
HIV Infections, AIDS
HIV and Kidney Function Study
Current methods to assess kidney function have not been tested in people who have HIV/AIDS population. Given effects of the disease as well as potential effects of the medications, it is possible that the methods currently used…
- Trial name
- NCT00905151
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Tufts Medical Center
Pneumonia
A Randomized Controlled Trial of Lung Ultrasound Compared to Chest X-ray for Diagnosing Pneumonia in the Emergency Department
The primary objective of this study is to determine if lung ultrasound (LUS) can replace chest x-ray (CXR) when evaluating patients with possible pneumonia.
- Trial name
- NCT01654887
- Testing
- Lung Ultrasound, Chest X-Ray
- Where
- United States
- Volunteers
- 191 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
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