Clinical trials: sponsored by Indiana University
Coronary Artery Disease
IU Health Krannert Personalized Medicine Study
Randomized controlled study to examine physician use of pharmacogenetic information in patients receiving antiplatelet medication after percutaneous coronary intervention (PCI).
- Trial name
- NCT02955121
- Testing
- Prescriber Access to Genetic Information
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Indiana University
Inflammation; Muscle
Effectiveness of Two Different Forms of Marine Oil on Indirect Markers of Muscle Damage and Soreness in Untrained Men
To evaluate the effects of PCSO-524®, and a blend of PCSO-24® (75%) and krill oil (25%) (ESPO-572®), on indirect markers of muscle damage, inflammation and soreness during recovery from muscle damaging exercise in untrained men.
- Trial name
- NCT03760757
- Testing
- ESPO-572®, PCSO-524®
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Indiana University
Viral Resistance, Treatment Failure
Virologic Treatment Failure and Drug Resistance in HIV-infected Kenyan Children (RESPECT)
The primary objective of this study is to use a well-characterized pediatric AMPATH cohort, with detailed medication-taking, drug level, and clinical data, to longitudinally evaluate treatment failure and drug resistance to…
- Trial name
- RESPECT (NCT03120065)
- Testing
- Electronic Dose Monitoring (MEMS)
- Where
- Kenya
- Volunteers
- 499 people
- Sponsor
- Rachel Vreeman, MD, MS
Depression, HIV
Depression Therapy to Improve Cardiovascular Risk in HIV
This trial will determine if depression treatment will reduce cardiovascular risk in HIV-infected patients already receiving HIV treatments.
- Trial name
- NCT02309372
- Testing
- Beating the Blues
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- Indiana University
Hypoxia, Altitude
Effect of an H1 Receptor Antagonist on Exercise Performance in Hypoxia
This study seeks to determine whether a simple, single intervention of Cetirizine / Zyrtec® use can improve exercise performance of active individuals when acutely exposed to altitude.
- Trial name
- NCT03192488
- Testing
- Cetirizine, Hypoxia
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Indiana University
Anesthesia, Pediatrics, Surgery
Comparative Study of Superficial Cervical Plexus Block and Nerve of Arnold Block and Incidence of PONV for Inner Ear Surgery
The investigators would like to compare the therapeutic and cost effectiveness of established therapies for postoperative nausea and vomiting to regional nerve blocks of the head and neck area an intervention known for analgesia…
- Trial name
- NCT02724033
- Testing
- regional nerve block, Antiemetic
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Indiana University
Heart Failure
Randomized Study of Organ Care System Cardiac for Preservation of Donated Hearts for Eventual Transplantation
The purpose of the study is to compare survival of both patients and newly transplanted hearts following heart transplantation among patients who were transplanted with donated hearts preserved on ice and those who were…
- Trial name
- PROCEEDII (NCT00855712)
- Testing
- Organ Care System, Cold Cardioplegia Solution
- Where
- 11 sites in United States, France and 2 more
- Volunteers
- 128 people
- Sponsor
- TransMedics
Pediatric Anesthesia, King Vision Video Laryngoscope Intubation
King Vision Video Laryngoscope Ambu (aBlade) System for Use in Children
This is a single center trial to evaluate the performance of the King Vision video laryngoscope in pediatric patients between the ages of one month and 10 years of age.
- Trial name
- NCT02841189
- Testing
- King Vision video Laryngoscope
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Enamel Caries
Evaluation of Efficacy of Sodium Monofluorophosphate (SMPF) Toothpastes on Enamel Lesion Remineralisation
Double-blind, randomized, 3 group in situ study to assess effect of three toothpastes on enamel remineralization, as measured by change in integrated mineral loss (∆∆Z).
- Trial name
- NCT04155658
- Testing
- Experimental Toothpaste containing 1450ppm SMFP, Toothpaste containing 1450ppm SMFP, Toothpaste with no fluoride
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Obesity
Potato Consumption and Energy Balance
A randomized, clinical trial will be performed to assess changes in body weight and fat mass with daily potato consumption versus a calorie-matched snack of almonds.
- Trial name
- NCT03518515
- Testing
- White potato (french fries), White potato (French fries), +seasoning, Almond
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Substance Use Disorders
Implementation and Evaluation of SBIRT
Alarming rates of unhealthy alcohol, non-prescription drug, and tobacco use highlight the preventable health risks of substance abuse and the urgent need to advance behavioral health systems.
- Trial name
- NCT03560076
- Testing
- SBIRT Training and Implementation Strategies
- Where
- United States
- Volunteers
- 2,562 people
- Sponsor
- Indiana University
Hypoplasminogenemia
A Single-patient Study of Repeat-dose Administration of Prometic Plasminogen (Human) Intravenous
These are single-patient studies with repeat-dose administration of ProMetic Plasminogen IV infusion in one adult and one child with hypoplasminogenemia.
- Trial name
- NCT03265171
- Testing
- Plasminogen (Human)
- Sponsor
- Prometic Biotherapeutics, Inc.
Heart Failure
Get With the Guidelines in ED Patients With Heart Failure
Approximately 20-30% of patients presenting with acute heart failure are discharged from the ED. Compared to patients discharged from the hospital, they more frequently return to the ED and hospital for further management.
- Trial name
- GUIDED-HF (NCT02519283)
- Testing
- GUIDED-HF, Standard of Care
- Where
- 15 sites in United States
- Volunteers
- 529 people
- Sponsor
- Vanderbilt University
Antibiotic Resistant Strain
A Trial of Encapsulated Fecal Microbiota for Vancomycin Resistant Enterococcus Decolonization
The objective of this study is to provide preliminary insight into the safety and efficacy of fecal microbiota transplantation (FMT) for the eradication of gastrointestinal carriage of vancomycin-resistant Enterococcus.
- Trial name
- NCT03063437
- Testing
- Encapsulated fecal microbiota preparation
- Where
- 2 sites in United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Microbiome Health Research Institute
Testicular Neoplasms
The Platinum Study Comparison Group
The patients enrolled on this new study will serve as an appropriate comparison group consisting of patients with the diagnosis of germ cell testicular cancer who were cured with surgical resection and did not receive…
- Trial name
- NCT02890030
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Lawrence Einhorn
Crohn's Disease
Acupuncture Treatment for Active Crohn's Disease
The purpose of this study is to observe the efficacy and safety of acupuncture and moxibustion for Crohn's disease and the regulation mechanism of intestinal microbiota and peripheral immunity.
- Trial name
- NCT02559037
- Testing
- Acupuncture and moxibustion
- Where
- China
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Cancer
Integrating an Occupational Therapy Health and Wellness Program Into an Existing Cancer Support Community
The number of cancer survivors today is growing exponentially and many survivors have unmet needs due to the late side effects of treatment.
- Trial name
- OT-HAWP (NCT03888547)
- Testing
- Occupational Therapy Health & Wellness Education
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Indianapolis
Hyperopia, Myopia
On-Eye Optical Quality of Lotrafilcon B Lenses Over 12 Hours
The current study aims to systematically investigate the diurnal variation in the optical quality of soft contact lenses on eye throughout the day. Subject reported quality of vision will also be evaluated.
- Trial name
- NCT03881670
- Testing
- Lotrafilcon B, lotrafilcon B with Hydraluxe
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Indiana University
Depression, Depressive Disorder
Study of Mind-Body Skills Groups for Adolescents With Depression in Primary Care
The Center for Mind -Body Medicine has developed a mind-body skills group program that incorporates meditation, guided imagery, breathing techniques, autogenic training, biofeedback, genograms, and self-expression through words…
- Trial name
- NCT03363750
- Testing
- mind-body-skills group
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Indiana University
Infant, Premature, Diseases, Bronchopulmonary Dysplasia
Growth of Airways and Lung Tissues in Premature and Healthy Infants
The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.
- Conditions
- Infant, Premature, Diseases, Bronchopulmonary Dysplasia, Asthma
- Trial name
- NCT00419588
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- Indiana University
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