Clinical trials: sponsored by New York University
Sickle Cell Anemia
Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea
The primary goal of the Phase III TWiTCH trial is to compare 24 months of alternative therapy (hydroxyurea) to standard therapy (transfusions) for pediatric subjects with sickle cell anemia and abnormally high (≥200 cm/sec)…
- Trial name
- TWiTCH (NCT01425307)
- Testing
- Hydroxyurea
- Volunteers
- 159 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Care Givers
Emotion Regulation Therapy to Address Distress Among Caregivers
The aim of this study is to adapt and pilot test a type of therapy called Emotion Regulation Therapy (ERT-C) for informal caregivers of patients with cancer.
- Trial name
- NCT02697357
- Testing
- Psychosocial Instruments, Emotion Regulation Therapy for Cancer Caregivers (ERT-C)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Healthy
Effects of Brain-stimulation on Metamemory Monitoring and Control
When people learn and remember information, it is often accompanied by a feeling of subjective confidence about whether or not information has been learned and accurately remembered.
- Trial name
- FOKhint (NCT03693729)
- Testing
- HD-tDCS
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Brooklyn College of the City University of New York
Knowledge, Attitudes, Practice, Burnout, Caregiver
Online Training & Certification for Competency in Dementia Friendly Hospital Care
This research study will evaluate the CARES Dementia-Friendly Hospitals online training and certification program for Allied Health Workers (nursing assistants, dietary aides, housekeeping employees, hospital transporters…
- Conditions
- Knowledge, Attitudes, Practice, Burnout, Caregiver, Job Satisfaction
- Trial name
- NCT04182282
- Testing
- CARES Dementia-Friendly Hospitals Online Training and Certification Program
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- HealthCare Interactive, Inc.
Rheumatoid Arthritis, Ankylosing Spondylitis
Comparative Effectiveness and Safety of Biosimilar and Legacy Drugs
In Canada and worldwide there is a need for updated independent real-world comparative effectiveness and safety data related to biologic drugs including biosimilar drugs.
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Ulcerative Colitis, Crohn's Disease
- Trial name
- NCT03729674
- Testing
- Biosimilar, Originator (legacy) drug
- Where
- Canada
- Volunteers
- 800 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Human Papillomavirus Infection
Quality Improvement Strategies to Increase Human Papillomavirus (HPV) Vaccination
HPV vaccination is at lower levels than the national goals. This study will evaluate the effectiveness of quality improvement strategies for increasing HPV vaccination coverage among adolescents in primary care clinics.
- Trial name
- NCT03442062
- Testing
- Assessment Feedback Incentives and eXchange, Physician-to-physician engagement, Active Intervention Control
- Where
- 3 sites in United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Retinopathy of Prematurity
Synergistic Pharmacologic Intervention for Prevention of ROP (SPIPROP Study)
Phase 2, open-label, randomized, multi-center studies in infants and premature infants are necessary to determine treatment and preventative strategies for ROP.
- Trial name
- SPIPROP (NCT02344225)
- Testing
- Caffeine citrate, Ibuprofen, Ketorolac
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- State University of New York - Downstate Medical Center
Cognitive Impairment, Executive Dysfunction
Case Studies: Promoting Strategy Use in Functional Activities
The purpose of the study is to provide evidence of feasibility, acceptability, patient satisfaction, and patient perceived benefit of the Multicontext (MC) approach.
- Conditions
- Cognitive Impairment, Executive Dysfunction, Acquired Brain Injury
- Trial name
- NCT04363645
- Testing
- Multicontext (MC) approach
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Weill Medical College of Cornell University
Educational Achievement
Increasing the Reach of Promising Dropout Prevention Programs: Examining the Trade-offs Between Scale and Effectiveness
The inability to consistently deliver at large scale promising education interventions is an important contributing cause to inequality in the U.S.
- Trial name
- NCT02889640
- Testing
- SAGA Innovations, Scale-up tutors, Standard Tutors
- Volunteers
- 6,600 people
- Sponsor
- University of Chicago
Anxiety, Stress
Transcranial Direct Current Stimulation (tDCS) Augments the Effects of Gamified, Mobile Attention Bias Modification
The present study tested whether transcranial direct current stimulation (tDCS) across the prefrontal cortex (PFC), versus sham stimulation, effectively augments the beneficial effects of a gamified attention bias modification…
- Trial name
- NCT04348812
- Testing
- ABMT, Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Breast Cancer
Developing a New Questionnaire About Patient Expectations of Breast Conserving Therapy
The purpose of this study is to develop a questionnaire to measure patient expectations of breast-conserving therapy (breast-conserving surgery and radiation).
- Trial name
- NCT02753673
- Testing
- qualitative interviews with patients, questionnaires
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Multiple Sclerosis
Effects of Acthar on Recovery From Cognitive Relapses in MS
The purpose of this study is to evaluate the effect of a medication called Acthar on recovery from multiple sclerosis-related relapses that impact cognition.
- Trial name
- NCT02290444
- Testing
- Adrenocorticotropic Hormone
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- State University of New York at Buffalo
Substance-related Disorders, Drug Addiction
Buprenorphine and Integrated HIV Care
The purpose of this study is to examine the efficacy of providing two levels of psychosocial support along with buprenorphine/naloxone (BUP) maintenance to opioid dependent patients receiving their care in an HIV clinical care…
- Conditions
- Substance-related Disorders, Drug Addiction, Human Immunodeficiency Virus, AIDS
- Trial name
- NCT00317460
- Testing
- Physician Management, Counseling
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Yale University
Alzheimer Disease, Early Onset, MCI
The Interactive Physical and Cognitive Exercise System
This study is intended to clarify the benefits to brain health and thinking processes that result from different forms of exercise.
- Conditions
- Alzheimer Disease, Early Onset, MCI, Aging, Mild Cognitive Impairment
- Trial name
- iPACES™ (NCT03069391)
- Testing
- physical exercise alone (PES) first, cognitive exercise alone (iCE) first, interactive Physical and Cognitive Exercise (iPACES™)
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Union College, New York
Critical Illness
Music Intervention for Agitation Reduction in the Pediatric Intensive Care Unit
The objective of this study is to administer music therapy to patients in the pediatric intensive care unit (PICU) in order to observe how music affects patient agitation, vital signs, and overall recovery in the unit.
- Trial name
- NCT03453814
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- State University of New York at Buffalo
Coronary Arteriosclerosis, Left Main Coronary Artery Disease
Registry on Left Main Coronary Artery Bifurcation Percutaneous Intervention
The slowly accruing evidence on the treatment of patients with left main coronary artery (LMCA) disease drove evolution in guidelines, that currently establish equivalent safety and efficacy for percutaneous coronary intervention…
- Trial name
- WE REMAIN EBC (NCT04321473)
- Testing
- PCI on left main
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Convergence Insufficiency
Office-based Vision Therapy for Improving Reading and Attention in Children With Convergence Insufficiency
CITT-ART is a multicenter study (8 locations around the United States) of 324 children ages 9 to <14 years with symptomatic convergence insufficiency (CI).
- Trial name
- CITT-ART (NCT02207517)
- Testing
- Office-based vergence/accommodative therapy
- Where
- 8 sites in United States
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- Salus University
PTSD, Trauma
Neurobehavioral Moderators of Post-traumatic Disease Trajectories
The research goal is to uncover the neurocognitive moderators of PTSD trajectories, by documenting clinical symptoms, cognitive functioning, and brain structure and function, one-, six- and fourteen months following a traumatic…
- Trial name
- NCT03756545
- Where
- Israel
- Volunteers
- 173 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Obesity, Weight Gain
Testing the Influence of Different Sugary Drink Warning Label Designs
The aim of this study is to compare different sugary drink labels to see which most influence knowledge, beliefs, purchase intentions and choices.
- Conditions
- Obesity, Weight Gain, Diabetes Type 2
- Trial name
- NCT03648138
- Testing
- Sugary drink warning labels
- Where
- United States
- Volunteers
- 1,016 people
- Sponsor
- University of Pennsylvania
Asthma
Open-Label Trial of the Use of Minocycline in the Treatment of Asthma
The tetracycline minocycline has, in addition to its anti-infective properties, anti-inflammatory properties which may be of use in the treatment of asthma.
- Trial name
- NCT00536042
- Testing
- Minocycline
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- State University of New York - Downstate Medical Center
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