Clinical trials: sponsored by Oslo University Hospital
Hiv, Sexually Transmitted Diseases
Evaluation of Implementation of Pre-exposure Prophylaxis (PrEP) in Norway
Despite the significant preventive efforts to reduce HIV infections in the past decades, the incidence in MSM has plateaued at a higher level after the turn of the millennium.
- Conditions
- Hiv, Sexually Transmitted Diseases, Mental Health Wellness 1
- Trial name
- NCT03436407
- Where
- 9 sites in Norway
- Volunteers
- 500 people
- Sponsor
- Oslo University Hospital
Hip Fracture
Association Between HRV and Postoperative Mortality in Hip Fracture Patients
165 patients admitted to two hospitals were included and short-time HRV measurements were obtained. Mortality data were gathered from the Norwegian central address register.
- Trial name
- HRVHip (NCT03426501)
- Volunteers
- 165 people
- Sponsor
- Vestre Viken Hospital Trust
Drug Usage
Cooperation for Improved Pharmacotherapy in Home-dwelling Elderly People Receiving Polypharmacy - The COOP Study
Polypharmacy increases the risk of adverse drug effects, interactions and other drug-related problems, and several studies indicate that inappropriate drug use is a major reason for poor health and impaired function in the…
- Trial name
- COOP (NCT02379455)
- Testing
- Comprehensive drug review
- Where
- Norway
- Volunteers
- 192 people
- Sponsor
- Oslo University Hospital
Cancer, Gastrointestinal Cancer
Long-term Cancer Risk in the Randomised Oslo Diet and Antismoking Study
This study examines the effect of a five-year multifactorial lifestyle intervention in the Oslo diet and antismoking study on long-term cancer risk.
- Conditions
- Cancer, Gastrointestinal Cancer, Lung Cancer, Urinary Tract Cancer
- Trial name
- NCT03410641
- Testing
- Diet and antismoking advice
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Hypertension
Nesiritide in Hypertension
Hypertension remains a global burden in cardiovascular disease leading to stroke, myocardial infarction, and heart failure. Its myocardial complications result from increased mechanical load on the heart.
- Trial name
- TENSE1 (NCT02608996)
- Testing
- Nesiritide
- Where
- 3 sites in Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Tibial Fractures
Reamed Nailing Versus Taylor Spatial Frame in Tibia Shaft Fractures
This is a randomised, bi-centre, prospective, clinical trial in patients with closed tibia shaft fractures. The fracture should be fresh/acute and seen within 3 weeks after the injury.
- Trial name
- NAFTI (NCT03388879)
- Testing
- Taylor Spatial Frame, Intramedullary nail
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Oslo University Hospital
Amputation
Early Active Finger Exercises in Replanted Fingers
A controlled randomized trial, including patients undergoing finger replantation surgery. The Control Group will receive a standardized post operative rehabilitation regime, whilst the Intervention Group will receive a…
- Trial name
- NCT03383640
- Testing
- Active exercises
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Lateral Epicondylitis
Physiotherapy or Acupuncture for Lateral Epicondylitis
Work-related upper extremity disorders are common problems in working populations in western countries. Lateral epicondylitis (LE) or tennis elbow is the most frequent type of soft tissue syndrome of the elbow, with an annual…
- Trial name
- NCT02321696
- Testing
- Acupuncture, Physiotherapy and eccentric exercise, Watchful waiting and eccentric exercise
- Where
- Norway
- Volunteers
- 36 people
- Sponsor
- Oslo University Hospital
Acute Kidney Injury, Deep Venous Thrombosis
Norwegian Intensive Care Unit Dalteparin Effect Study
The main purpose of the NORIDES study is to investigate the effect of pharmacological thromboprophylaxis with low molecular weight heparins (LMWHs) in critically ill patients, and how it is affected by presence of acute kidney…
- Trial name
- NORIDES (NCT01721928)
- Testing
- Continuous venovenous hemodialysis
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Oslo University Hospital
Cerebral Palsy, Spastic, Hemiplegic Cerebral Palsy
Changes in Muscle Activity of Children With Spastic Unilat Cerebral Palsy Using 2 Types of Ankle-foot Orthoses to Walk
The aim of this study is to investigate if ankle-foot orthoses affect changes in muscle activity of children with spastic unilateral cerebral palsy during walking.
- Trial name
- NCT03361930
- Testing
- Ankle-foot orthosis
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
Otitis Media With Effusion, Eustachian Tube Disorder
Novel Imaging of the Eustachian Tube; Patient Study
The purpose of the study is to establish wether a contrast medium applied to the middle ear can be used to diagnose pathology in the auditory tube.
- Trial name
- CT-ET (NCT02282540)
- Testing
- Iodixanol to the Eustachian tube
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Depression
Cognitive Rehabilitation in Patients With Depression
Depression is a highly prevalent and debilitating mental disorder, ranked one of the leading causes of disability worldwide. Several studies have identified neuropsychological deficits in populations of depressed patients…
- Trial name
- NCT03338413
- Testing
- Goal Management Training, Computerized Cognitive Training
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Lovisenberg Diakonale Hospital
Femoral Neck Fractures
Undisplaced Femoral Neck Fractures in the Elderly: A Trial Comparing Internal Fixation to Hemiarthroplasty
Clinical research during the last ten years has revealed that elderly patients with a displaced femoral neck fracture should be treated with arthroplasty instead of closed reduction of the fracture followed by internal fixation…
- Trial name
- NCT01770769
- Testing
- Hemi - arthroplasty, internal fixation
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- University Hospital, Akershus
Soft Tissue Shoulder Injury, Rotator Cuff Tear
Early Clinical Examination and Ultrasonography Screening of Acute Soft Tissue Shoulder Injuries
The purpose of the study is to determine whether the introduction of early ultrasonography screening will change the diagnostic spectrum of soft tissue shoulder injuries in patients aged forty years or more.
- Trial name
- NCT02644564
- Testing
- Ultrasonography
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Skin Neoplasms, Carcinoma, Basal Cell
New Versus Approved Methyl-aminolevulinate Photodynamic Therapy (MAL-PDT) Regime in Basal Cell Carcinoma (BCC)
Basal cell carcinoma (BCC) is the most common malignant skin lesion in white adults. It is a slow-growing tumour which despite low metastatic potential may cause significant local tissue destruction and patient morbidity.
- Trial name
- NCT01482104
- Testing
- MAL-PDT re-treatment, usual MAL-PDT
- Where
- 9 sites in Norway
- Volunteers
- 277 people
- Sponsor
- Norwegian University of Science and Technology
Uveal Malignant Melanoma
Liver Transplantation and Uveal Malignant Melanoma
Patients with uveal malignant melanoma with liver metastases have median survival of less than 12 months. There is no established treatment showing increased overall survival.
- Trial name
- NCT01311466
- Testing
- Liver transplantation
- Where
- Norway
- Volunteers
- 2 people
- Sponsor
- Oslo University Hospital
Breast Cancer
Safety of Breast Conserving Treatment in Locally Advanced Breast Cancer Receiving Neoadjuvant Treatment
The study explores the safety of breast conserving treatment (BCT)(defined as complete removal of tumor deposits) after neoadjuvant treatment for locally advanced breast cancer.
- Trial name
- NeoBCT (NCT02017496)
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Oslo University Hospital
Spinal Cord Injured, Tetraplegia
The Role of Melatonin in the Regulation of Blood Coagulation
The main aim is to examine the influence of daylight and melatonin on the temporal variations of hemostatic factors with key roles in the hemostatic process and its regulation.
- Trial name
- COME (NCT01741389)
- Testing
- Melatonin ("Circadin")
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Chronic Fatigue Syndrome, Coping
Coping With Chronic Fatigue Syndrome: Development of a Community-based Patient Education Program
The aim of the study is to develop, carry out, evaluate and measure the effects of a new patient education program for patients with Chronic Fatigue Syndrome (CFS)in primary healthcare.
- Conditions
- Chronic Fatigue Syndrome, Coping, Patient Education
- Trial name
- NCT01765725
- Testing
- Patient education program
- Where
- Norway
- Volunteers
- 146 people
- Sponsor
- Oslo University Hospital
Actinic Keratosis
Fractional Laser-assisted Daylight Photodynamic Therapy Versus Daylight Photodynamic for Treatment of Actinic Keratoses
Organ transplant recipients (OTR) have an increased risk of non-melanoma skin cancer, in particular squamous cell carcinoma (SCC), often developing in areas of field cancerization, areas with multiple precancerous actinic…
- Trial name
- NCT01898936
- Testing
- Pretreatment with CO2 laser before photodynamic therapy, Only photodynamic therapy
- Where
- Norway
- Volunteers
- 12 people
- Sponsor
- Oslo University Hospital
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