Clinical trials: sponsored by Samsung Medical Center
Chronic Obstructive Pulmonary Disease
A Study to Evaluate Efficacy and Safety Profile of Zabofloxacin Tablet 400mg and Moxifloxacin Tablet 400mg
The purpose of this study is to Evaluate the Efficacy and Safety Profiles of oral multiple dose of Zabofloxacin Tablet 400 mg.
- Trial name
- DW224-III-3 (NCT01658020)
- Testing
- Zabofloxacin, Moxifloxacin
- Where
- South Korea
- Volunteers
- 345 people
- Sponsor
- Dong Wha Pharmaceutical Co. Ltd.
Chronic Renal Disease
Kidney Graft Function Under the Immunosuppression Strategies
To demonstrate that cyclosporine-sparing immunosuppressions with the standard dose of Enteric-Coated Mycophenolate Sodium would preserve renal graft function after transplantation without an increase of incidences of adverse…
- Trial name
- MyLowCsA (NCT01817322)
- Testing
- Standard Dose of Myfortic and Reduced Dose of Myfortic, Prednisolone OR methylprednisolone OR deflazacort injected both control group and experimental group, Basiliximab injected both control group and experimental group
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Mild Cognitive Impairment
A Pilot Study of tDCS for Mild Cognitive Impairment
The primary objective of this preliminary study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Mild Cognitive Impairment (MCI)
- Trial name
- NCT02227966
- Testing
- Yband (YDT-201N)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Alzheimer's Disease
A Pilot Study of tDCS for Mild to Moderate Alzhemier's Disease
The primary objective of this preliminary study is to investigate whether the transcranial direct current stimulation (tDCS) improves the cognitive function in patients with Alzheimer's disease
- Trial name
- NCT02227953
- Testing
- Yband (YDT-201N)
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Samsung Medical Center
Off Pump Coronary Artery Bypass Graft
Volatile Versus Propofol Anesthesia in OPCAB
Off pump coronary artery bypass graft (OPCAB) still requires myocardial protection owing to intermittent regional ischemic episode.
- Trial name
- NCT02222142
- Testing
- Isoflurane
- Where
- South Korea
- Volunteers
- 1,080 people
- Sponsor
- Samsung Medical Center
Pancreatic Neoplasms
Randomized, Controlled Trial of Endoscopic Ultrasound-Guided Bilateral Celiac Plexus Neurolysis vs Celiac Ganglia Neurolysis to Control Pain in Inoperable Pancreatic Cancer Patients With Inadequate Pain Control by Pain Killer
Pancreatic cancer related pain can be difficult to control, even with high doses of narcotics, whose adverse effects may further impair quality of life.
- Trial name
- NCT02220062
- Testing
- EUS-CPN, EUS-CGN
- Volunteers
- 166 people
- Sponsor
- Samsung Medical Center
End Stage Renal Disease
Tolerance Induction in Living Donor Kidney Transplantation With Hematopoietic Stem Cell Transplantation
Kidney transplantation (KT) requires a life-long immune suppression (IS). It has been well-known that long-term IS inevitably causes various complication e.g.
- Trial name
- NCT02199301
- Testing
- Transplantation Conditioning for BMT
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- Samsung Medical Center
General Anesthesia, Total Intravenous Anesthesia
Predicting Bispectral Index Values by Estimated Effect-site Concentration of Propofol and Remifentanil Displayed on the Target-centered Infusion Pump
The BIS is influenced by multiple parameters, such as age,gender, body weight, height, muscle relaxants, hepatic function, co-administered drugs, surgical stimulation, but is thought to be influenced mainly by propofol and…
- Conditions
- General Anesthesia, Total Intravenous Anesthesia, Bispectral Index Monitoring
- Trial name
- NCT01604226
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Coronary Artery Bypass Graft, Median Sternotomy
Risk Factors of Sternal Wound Infection After Coronary Artery Bypass Graft
The investigators are trying to evaluate the performance of neutrophil and lymphocyte counts as a risk factor of deep sternal wound infection after coronary artery bypass graft surgery.
- Trial name
- NCT01629030
- Where
- South Korea
- Volunteers
- 1,850 people
- Sponsor
- Samsung Medical Center
Myoma
Multi-center Prospective Study on E-NOTES for Myomectomy With Traction of Multidirectional Sutures
Primary objectives : To investigate technical feasibility and postoperative morbidity after E-NOTES for Myomectomy with Traction of Multidirectional Sutures Secondary objectives : To investigate postoperative pain after E-NOTES…
- Trial name
- E-NOTES (NCT01829022)
- Testing
- E-NOTES
- Where
- 2 sites in South Korea
- Volunteers
- 35 people
- Sponsor
- National Cancer Center, Korea
Psoriasis Vulgaris
Study for Treatment With Calcipotriol/Betamethasone Dipropionate Gel in Korean Patients With Psoriasis Vulgaris
The combination of calcipotriol and betamethasone dipropionate used in an ointment formulation (Daivobet® ointment) has shown to have an excellent efficacy and safety in the short-term and long-term management of psoriasis…
- Trial name
- TRIANGLE (NCT02004574)
- Testing
- Calcipotriol/betamethasone dipropionate gel
- Where
- South Korea
- Volunteers
- 201 people
- Sponsor
- Jooheung Lee
Overactive Bladder
Observational Study to Estimate the Dry Mouth in OAB Patients With Solifenacin
A prospective, multicenter, observation study to estimate the dry mouth in OAB patients with solifenacin
- Trial name
- OAB (NCT01437670)
- Testing
- solifenacin 5mg, 10mg
- Where
- South Korea
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Biliary Tract Cancer
Phase II Study of Gemcitabine and TS-1 in Biliary Trat Cancer
In current study, we evaluate the efficacy of gemcitabine and TS-1 combination chemotherapy in advanced BTC.
- Trial name
- GetBil (NCT01171755)
- Testing
- Gemcitabine TS-1
- Volunteers
- 19 people
- Sponsor
- Samsung Medical Center
Breast Neoplasms
Perioperative Inflammation and Breast Cancer Outcome
It is increasingly recognized the NSAIDS (nonsteroidal antiinflammatory drug) might prevent the several cancers. In breast cancer, the role of NSAIDS (nonsteroidal antiinflammatory drug) has been suggested.However, there was no…
- Trial name
- NCT02141139
- Testing
- NSAIDS (ketorolac and ibuprofen)
- Where
- South Korea
- Volunteers
- 1,568 people
- Sponsor
- Samsung Medical Center
Gastroesophageal Reflux Disease
The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERD
PPI test;empirical trial with high-dose proton-pump inhibitors (PPIs) has been shown to be a sensitive tool for diagnosing patients with GERD.
- Trial name
- NCT00539786
- Testing
- Proton pump inhibitor (rabeprazole)
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Bladder Cancer
Salvage Docetaxel for Pretreated Urothelial Cancer
Based on the previous clinical experience in other cancers, and considering the absence of current standard salvage regimens, the single agent docetaxel is selected as the regimen for this phase II study.
- Trial name
- NCT01711112
- Testing
- Docetaxel
- Where
- South Korea
- Volunteers
- 31 people
- Sponsor
- Samsung Medical Center
Unresectable, Metastatic Biliary Tract Carcinoma
Gemcitabine/Oxaliplatin (GEMOX) With or Without Erlotinib (Tarceva) in Advanced Biliary Tract Carcinoma
The purpose of this study is to determine whether Gemcitabine/Oxaliplatin (GEMOX) with or without Erlotinib (Tarceva) is effective in the treatment of unresectable, metastatic biliary tract carcinoma.
- Trial name
- NCT01149122
- Testing
- Gemcitabine/Oxaliplatin, Gemcitabine/Oxaliplatin with Erlotinib (Tarceva)
- Where
- South Korea
- Volunteers
- 266 people
- Sponsor
- Samsung Medical Center
Advanced Biliary Tract Adenocarcinoma
Sunitinib as Second-line Treatment in Advanced Biliary Tract Carcinoma
The purpose of this study is to determine whether sunitinib as second-line treatment in advanced biliary tract carcinoma
- Trial name
- NCT01082809
- Testing
- Sunitinib
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Samsung Medical Center
Hepatocellular Carcinoma, Renal Cell Carcinoma
Genome-wide Association Study to Predict Treatment Response for Molecular Targeted Therapy in Hepatocellular Carcinoma and Renal Cell Carcinoma
All Hepatocellular carcinoma and Renal cell carcinoma patients who receive molecular targeted therapy will be candidates for the study.
- Trial name
- NCT01482520
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Polymorphism, CYP19
Aromatase (CYP19) Polymorphism Between AI-responsive and AI-resistant Breast Cancer in Korea
Aromatase(CYP19)inhibitor is one of the major antihormonal drug for breast cancer in postmenopausal women. The variation of CYP19 may affect the effect of aromatase inhibitor.
- Conditions
- Polymorphism, CYP19, Aromatase Inhibitor
- Trial name
- CYP19 (NCT01137136)
- Where
- South Korea
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
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