Clinical trials: completed
Stage III Periodontitis
Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management
To better understand and treat your gum disease, dentists now use a system that stages its severity and grades its speed, rather than using old labels.
- Trial name
- NCT07316023
- Testing
- Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded nanoparticles, Non- surgical periodontal therapy followed by photodynamic therapy with ICG-loaded macroparticles, Non- surgical periodontal therapy only
- Where
- Egypt
- Volunteers
- 27 people
- Sponsor
- Nada Mahmoud Soliman
Stroke
The Effects of Extracorporeal Shock Wave Therapy on Upper Extremity Spasticity and Function in Patients With Stroke
Spasticity is a common complication after stroke and can limit upper extremity motor control and activities of daily living. Radial extracorporeal shock wave therapy (rESWT) is a non-invasive treatment that has been investigated…
- Trial name
- NCT07532187
- Testing
- Radial Extracorporeal Shock Wave Therapy (rESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Hypertension
Accuracy Testing of Validated and Non-validated Home BP Devices Sold on the Online Market.
This study aims to assess whether validated and non-validated blood pressure measuring devices sold on the online market are accurate in regards to the mean awake BP from ambulatory blood pressure monitoring.
- Trial name
- VALID-HomeBP (NCT06688409)
- Testing
- awake ABPM
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Port-a-cath Occlusion, Normal Saline
Normal Saline Versus Heparin Intermittent Flushing for the Prevention of Occlusion in Port-a-Cath
Purpose: An evidence implementation of a randomized controlled trial for whether there is the difference in intermittent flushing 0.9% normal saline and heparin? Design: a single-blind randomized controlled trial Method: This…
- Conditions
- Port-a-cath Occlusion, Normal Saline, Heparin Lock
- Trial name
- NCT05707936
- Testing
- Normal Saline Flush 20 ml, Normal Saline Flush 10 ml, Heparin Flush (1000 USP, 10ml)
- Where
- Taiwan
- Volunteers
- 192 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Spontaneous Urticaria
Efficacy and Safety of LP-003 in Patients With CSU Who Remain Symptomatic Despite Antihistamine (H1) Treatment
The study is a Phase II, multicenter, randomized, double-blind study to evaluatethe efficacy and safety of LP-003 administered subcutaneously as an add-on therapy for the treatment of adult patients aged 18-75 who have been…
- Trial name
- NCT06228560
- Testing
- LP-003, Omalizumab
- Where
- 17 sites in China
- Volunteers
- 202 people
- Sponsor
- Longbio Pharma
Pain, Acute Post-Operative, Anxiety
Effects of Reflexology and Cold Application Before Chest Tube Removal in CABG Patients
This randomized controlled trial evaluated the effects of foot reflexology and cold application, administered separately before chest tube removal, on pain, state anxiety, and physiological parameters in patients following…
- Conditions
- Pain, Acute Post-Operative, Anxiety, Chest Tube Removal, Coronary Artery Bypass
- Trial name
- NCT07528482
- Testing
- Reflexology, Cryotherapy alone
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ankara University
Naso-Orbito-Ethmoidal, Fractures
REDUCTION ACCURACY IN NASO-ORBITO-ETHMOIDAL FRACTURES AFTER VIRTUAL REDUCTION AND FIXATION USING PRE-ADAPTED MINIPLATES
This study aims to assess the reduction accuracy of Naso-orbito-ethmoidal (NOE) fractures using pre-adapted titanium miniplates based on a virtually reduced 3D model.
- Trial name
- NCT07791095
- Testing
- pre-adapted titanium miniplates based on a virtually reduced 3D model
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Alexandria University
Pain After Extracorporeal Shock Wave Lithotripsy, Palmitoylethanolamide
Palmitoylethanolamide vs Ibuprofen for Pain After ESWL
Pain after extracorporeal shock wave lithotripsy (ESWL), a non-surgical procedure used to treat kidney stones, is common and is usually treated with non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen.
- Trial name
- NCT07316660
- Testing
- Palmitoylethanolamide (PEA), Ibuprofen (Brufen®)
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Benha University
Breast Cancer, Breast Cancer Female
UPPER EXTREMITY FUNCTION AND LYMPHEDEMA IN BREAST CANCER SURVIVORS
In this study, the investigators investigated upper extremity function and breast cancer-related lymphedema in individuals following breast cancer surgery and treatments
- Trial name
- NCT07876375
- Where
- Turkey (Türkiye)
- Volunteers
- 175 people
- Sponsor
- Pamukkale University
Quality of Health Care, Patient Safety
CITE: Clinical Inference Tethered to Evidence - a Retrieve-and-verify Layer for AI Care Plans
This trial evaluates CITE, a retrieve-and-verify layer that audits an AI-generated care plan against a full-text evidence corpus and flags patient-specific codifiable safety hazards to the clinician.
- Conditions
- Quality of Health Care, Patient Safety, Clinical Decision Support
- Trial name
- CITE (NCT07718893)
- Testing
- CITE evidence-grounding retrieve-and-verify layer, AI care plan with safety guardrails
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Waymark
Older Adults, Older Adults (65 Years and Older)
SOC-based Behavioral Intervention to Promote Walking
Drawing on the Selection, Optimization, and Compensation (SOC) model of adaptive development, this study tested whether a structured behavioral intervention could enhance walking activity and well-being through improvements in…
- Trial name
- SOCWalk (NCT07312331)
- Testing
- SOC-based walking intervention, general health education program
- Where
- China
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Ling Yang
Acute Lymphoblastic Leukemia
Neurostimulation In Adult Survivors of Childhood Acute Lymphoblastic Leukemia (ALL)
Long-term survivors of ALL are at-risk for neurocognitive impairment, particularly in the area of executive functioning. Relatively limited research has focused on interventions for improving neurocognitive outcomes in long-term…
- Trial name
- NCT04007601
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- St. Jude Children's Research Hospital
Geographic Atrophy
A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic Atrophy
This study is being conducted in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) to determine if intravitreal (IVT) injections of ANX007 reduce GA lesion growth rate.
- Trial name
- ARCHER (NCT04656561)
- Testing
- ANX007
- Where
- 53 sites in United States, Australia and 1 more
- Volunteers
- 270 people
- Sponsor
- Annexon, Inc.
Venous Thromboembolism
Comparison of Bleeding Risk Between Rivaroxaban and Apixaban: The Pilot Study
This vanguard pilot study compares rivaroxaban and apixaban, two of the new oral blood thinners for the treatment of blood clots. Half of the patients will receive apixaban and half will receive rivaroxaban.
- Trial name
- COBRRA Pilot (NCT02559856)
- Testing
- Apixaban, Rivaroxaban
- Where
- 4 sites in Canada
- Volunteers
- 71 people
- Sponsor
- Ottawa Hospital Research Institute
Postoperative Pain
Subcostal Transversus Abdominus , Erector Spinae and Paravertebral Blocks Effects on Laparoscopic Cholecystectomy Cases
Sixty patients with ASA (American Society of Anesthesiologist) I-II physical status between the ages of 20-60 were randomized into three groups: TAP block group (Group T), ESP block group (Group E) and PVB group (Group P).
- Trial name
- NCT05398406
- Testing
- Subcostal TAP Block, ESP Block, Paravertebral Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Yuzuncu Yil University
Fasting Ramadan
Effect of Ramadan Fasting on Kidney Function and Proteinuria in Patients With Glomerulonephritis
This research aims to assess effects of ramadan fasting on kidney function and proteinuria in patients with glomerulonephritis.
- Trial name
- NCT06327009
- Testing
- fasting month of ramadan
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Alexandria University
Swimmer Shoulder
Combined Effect of Biofeedback and Scapular Stabilization Exercises in Children With Swimmer's Shoulder
The purpose of this study is to investigate the combined effect of biofeedback and scapular stabilization exercises on swimmer's shoulder in pediatric elite swimmers.
- Trial name
- NCT07067216
- Testing
- Designed scapular stabilization using pressure biofeedback, Designed physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Cerebral Infarction
Edaravone-Sodium Ozagrel Comparative Post-Marketing Study on Acute Ischemic Stroke
This study is randomized, Sodium Ozagrel (Thromboxane A2 Synthase Inhibitor) controlled study on acute ischemic stroke. The primary endpoints were the rate of patients with modified Rankin Scale score of 0-1 at 3 months.
- Trial name
- NCT00200356
- Testing
- Edaravone, Sodium Ozagrel
- Volunteers
- 401 people
- Sponsor
- Shionogi
Triple Negative Breast Cancer
Effects of MK-3475 (Pembrolizumab) on the Breast Tumor Microenvironment in Triple Negative Breast Cancer
Assess response to pembrolizumab in both primary tumor, normal breast stroma, circulating lymphocytes and serum exosomes in treatment naive triple negative breast cancer (TNBC) patients.
- Trial name
- Pembro/IORT (NCT02977468)
- Testing
- Merck 3475 Pembrolizumab, Intraoperative radiation therapy (IORT)
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- Columbia University
Airway Remodeling, Chronic Obstructive Pulmonary Disease
Effect of Tiotropium on Airway Remodeling in Patients With Early Stage COPD Accessed by Optical Coherence Tomography
This randomized, open-label, three-arm clinical trial evaluated the effects of tiotropium on airway remodeling in patients with GOLD stage 1 COPD using endobronchial optical coherence tomography (EB-OCT).
- Trial name
- NCT03842839
- Testing
- Tiotropium Inhalation Powder [Spiriva] 0.018mg, Salbutamol sulphate aerosol (Ventolin) 0.1mg
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Guangzhou Institute of Respiratory Disease