Clinical trials: unknown status
Breast Cancer
Paclitaxel Followed by FEC Versus Paclitaxel and RAD001 Followed by FEC In Women With Breast Cancer
The goal of this clinical research is to learn if RAD001 given in combination with chemotherapy will turn off the signaling pathway (a chain of information that tells cancer cells to grow quickly) and make the chemotherapies…
- Trial name
- NCT00499603
- Testing
- Paclitaxel, 5-Fluorouracil, Epirubicin
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- M.D. Anderson Cancer Center
Polypoidal Choroidal Vasculopathy
Short-term Efficacy of Intravitreal Afilibercept Depending on Subtypes of Polypoidal Choroidal Vasculopathy: Polypoidal Choroidal Neovascularization or Idiopathic Choroidal Vasculopathy
To compare the short-term effect of intravitreal aflibercept injection between two subtypes of polypoidal choroidal vasculopathy
- Trial name
- NCT02597855
- Testing
- Aflibercept, Indocyanine green angiography (intraveonus indocyanine green dye)
- Where
- South Korea
- Volunteers
- 29 people
- Sponsor
- Yeungnam University College of Medicine
Coronary Artery Disease
NeoVas Bioresorbable Coronary Scaffold First-in-Man Study
The NeoVas First-in-Man study is a prospective, two centers, single arm trial, which will enroll a total of 30 patients. The hypothesis of this study is to evaluate clinical feasibility, safety, and efficacy of NeoVas…
- Trial name
- NCT02195414
- Testing
- NeoVas BCS
- Where
- 2 sites in China
- Volunteers
- 31 people
- Sponsor
- Lepu Medical Technology (Beijing) Co., Ltd.
Tracheal Diseases
Laryngo-Tracheal Tissue-Engineered Clinical Transplantation
The proposed protocol will involve the replacement of the trachea using a synthetic bioengineered scaffold seeded with autologous mononuclear cells as an intraoperative solution for patients with with benign and malignant…
- Trial name
- NCT01997437
- Testing
- Stem-cell seeded bioartificial tracheal scaffold
- Where
- Russia
- Volunteers
- 6 people
- Sponsor
- Kuban State Medical University
Muscle Relaxation
Effectiveness of Sugammadex in LMS Surgery
This study is comparing of rocuronium-sugammadex and succinylcholine during LMS surgery that is characterized by short operation time, required intense paralysis and ambulatory setting, has not been investigated.
- Trial name
- NCT02329964
- Testing
- Sugammadex, Neostigmine
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Gastroesophageal Reflux Disease
Narrow-band Imaging, Autofluorescence Imaging and Gastroesophageal Reflux Disease
Aim of this study is to compare the efficacy of narrow band imaging (NBI) and autofluorescence imaging (AFI) to distinguish subtle mucosal change related to acid reflux that is not visible in standard white light imaging (WLI)…
- Trial name
- NCT01504971
- Testing
- symptom questionaire, pH monitoring, Tri-modal imaging endoscopy
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Edentulous
Comparison of Masticatory Efficiency Between Complete Denture With Zero-degree Teeth and Anatomic Teeth in Patients With Severely Resorbed Ridge
This study aims to evaluate masticatory efficiency of the zero-degree teeth complete denture in treatment of edentulous patients of severely resorbed ridge.Patients will be crossed over to be treated with zero-degree teeth…
- Trial name
- NCT02359955
- Testing
- zero degree teeth, anatomic teeth
- Volunteers
- 20 people
- Sponsor
- Haixin Qian
Metastatic Breast Cancer
Phase II Study of Capecitabine and Cisplatin to Treat Metastatic Triple Negative Breast Cancer
It is a phase II trial to explore the efficacy and safety of cisplatin plus capecitabine in anthracycline and taxane-pretreated metastatic triple negative breast cancer patients.
- Trial name
- NCT01928680
- Testing
- Cisplatin/Capecitabine
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Chinese Academy of Medical Sciences
Restauration in Situ, Final Loss of Restauration
Single Retainer All-Ceramic Resin-bonded Fixed Dental Protheses
The purpose of this prospective study was to evaluate the clinical outcome of all-ceramic RBFDP with a cantilevered single-retainer design made from zirconia ceramic.
- Conditions
- Restauration in Situ, Final Loss of Restauration, Debonded Restauration
- Trial name
- NCT01411592
- Testing
- Multilink, Panavia 21 TC
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Coronary Artery Disease
CYPRESS - CYPHER for Evaluating Sustained Safety
CYPRESS: A Prospective,Randomized,Multi-Center,Double-Blind Trial to Assess the Effectiveness and Safety of Different Durations of Dual Anti-Platelet Therapy (DAPT) in Subjects Undergoing Percutaneous Coronary Intervention with…
- Trial name
- NCT00954707
- Testing
- Clopidogrel & Aspirin, Prasugrel & Aspirin
- Where
- United States
- Volunteers
- 2,509 people
- Sponsor
- Cordis US Corp.
Coronary Artery Disease, Coronary Atherosclerosis
Study Comparing the CYPHER® ELITE™ to the CYPHER® Bx VELOCITY® Sirolimus-Eluting Stent Systems
The objective of this study is to show similar (non-inferior) safety and effectiveness between CYPHER® ELITE™ and CYPHER® Bx VELOCITY® Sirolimus-Eluting Stent Systems in a prospective, multi-center, randomized clinical study for…
- Trial name
- ELITE (NCT00715884)
- Testing
- CYPHER® ELITE™ Sirolimus-Eluting Stent System, CYPHER® Bx VELOCITY® Sirolimus-eluting Stent System
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Cordis US Corp.
Metastatic Breast Cancer
A Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Chemotherapy in Untreated Metastatic Breast Cancer (RIBBON 1)
This is a Phase III, multicenter, randomized, placebo-controlled trial designed to evaluate the efficacy and safety of bevacizumab in combination with chemotherapy compared with chemotherapy alone in subjects with previously…
- Trial name
- NCT00262067
- Testing
- Bevacizumab, Chemotherapy
- Where
- 92 sites in United States, Australia and 20 more
- Volunteers
- 1,237 people
- Sponsor
- Genentech, Inc.
Parkinson's
Apolipoprotein D (ApoD) In Human Serum As Marker Of Parkinson's Disease
In Italy affected people are 200,000 and every year Parkinson new cases are 10,000. Aging is the principle risk factor of Parkinson with the possibility of its development doubling every five years after 65.
- Trial name
- ApoD (NCT01467960)
- Where
- Italy
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Privatklinik Villa Melitta
Osteoarthritis of Knee
Comparison of Outcomes in Mobile and Fixed-bearing Total Knee Arthroplasty
The purpose of this study is to compare the clinical and radiological outcomes of mobile-bearing with that of fixed-bearing in total knee arthroplasty.
- Trial name
- NCT01027819
- Testing
- Mobile bearing, Fixed bearing
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Non-small Cell Lung Cancer
Curative Effect Study of Endostatin Combined With Chemoradiotherapy to Non-small-cell Lung Cancer
To evaluate the efficacy and safety of Endostar combined with concurrent chemo-radiotherapy (CCRT) in patients with unresectable stage III non-small-cell lung cancer (NSCLC).
- Trial name
- DP-EN-RT (NCT01218594)
- Testing
- Endostatin
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Sun Yat-sen University
Recurrent Hernia
Review of Complex Recurrent Hernia Repair
Abdominal wall incisional hernia is a common finding in patients who have undergone previous intra-abdominal surgeries. Common methods of abdominal fascial closure include primary closure, mesh inlay versus onlay, with or without…
- Trial name
- BARS (NCT01644695)
- Testing
- Bony Anchoring Reinforcement System
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Institute For Advanced Reconstruction
Coronary Artery Disease
SYNTAX Study: TAXUS Drug-Eluting Stent Versus Coronary Artery Bypass Surgery for the Treatment of Narrowed Arteries
The SYNTAX trial is designed to determine the best treatment for patients with complex coronary disease (blocked or narrowed arteries in both the right and left sides of the heart) by randomizing patients to receive either…
- Trial name
- SYNTAX (NCT00114972)
- Testing
- Polymer-based Paclitaxel-Eluting TAXUS Express2-SR Stent, Coronary Artery Bypass Surgery
- Where
- 106 sites in United States, Austria and 16 more
- Volunteers
- 1,800 people
- Sponsor
- Boston Scientific Corporation
Skin Aging
Safety and Efficacy Evaluation of Erbium Treatment
The purpose of this research study is to evaluate the safety and effectiveness of erbium lasers for dermatological cosmetic procedures.
- Trial name
- NCT00766376
- Testing
- Erbium laser
- Where
- 5 sites in United States
- Volunteers
- 151 people
- Sponsor
- Palomar Medical Technologies, Inc.