Clinical trials: not yet recruiting
Healthy Volunteer
Discovering Determinants of Food Intake by Application of Artificial Intelligence to Complex, High-Dimensional Data
Background: Many people in the United States are overweight or obese. Researchers want to learn why some people can overeat and not gain weight, whereas others who do not overeat still gain weight.
- Trial name
- NCT07637656
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity
Puerto Rican Obesity Intervention for Men
The goal of this clinical trial is to address the high rates of overweight/obesity in Puerto Rican (PR) men. The main question it aims to answer is whether virtual culturally relevant classes supporting physical activity and…
- Trial name
- NCT06440551
- Testing
- TeleSalud Healthy Eating- Physical Activity/Sedentary Behavior (HE-PA/SB), TeleSalud General Health Intervention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Chronic Low Back Pain, Urinary Incontinence
Radiofrequency and Pelvic Floor-Core Exercise for Chronic Low Back Pain in Women With Pelvic Floor Dysfunction
The goal of this clinical trial is to learn whether capacitive-resistive radiofrequency, a supervised core and pelvic floor exercise programme, or both together reduce low back pain in premenopausal women with chronic…
- Conditions
- Chronic Low Back Pain, Urinary Incontinence, Pelvic Floor Disorders
- Trial name
- NCT07906431
- Testing
- Capacitive-resistive radiofrequency, Lumbopelvic-pelvic floor therapeutic exercise
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- SERGIO MONTERO NAVARRO
Moderate to Severe Insomnia
HALO Clarity™ Cranial Alternating Current Stimulation Therapy for Adults With Moderate-to-Severe Insomnia
A prospective, decentralized, individually-randomized, triple-blind* sham-controlled, superiority trial to evaluate the safety and efficacy of HALO Clarity™ device in reducing insomnia severity.
- Trial name
- NCT07659366
- Testing
- Transcranial alternating current stimulator
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Nexalin Technology
Diabetes Mellitus (Type 2), Prediabetes
Evaluation of the Effectiveness of Implementing a Screening Strategy for the Diagnosis of Prediabetes and Type 2 Diabetes Mellitus in Primary Health Care in a Brazilian Municipality
Primary objective: To evaluate the effectiveness of the ARISE strategy on the proportion of individuals with confirmed T2DM diagnosis, per protocol criteria based on the PCDT-DM2 (Clinical Protocol and Therapeutic Guidelines for…
- Trial name
- ARISE (NCT07846319)
- Testing
- ARISE Strategy
- Where
- 2 sites in Brazil
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- epHealth
ACDF Surgery
Post-operative Outcomes of Anterior Cervical Discectomy and Fusion Surgery With and Without Drain Placement
Anterior Cervical Discectomy and Fusion (ACDF) is a widely performed surgical procedure used to treat cervical spondylosis and cervical disc herniations with cervical nerve root compression and or cervical spinal cord compression…
- Trial name
- NCT06938607
- Testing
- Drain
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Nebraska
Cholangitis, Ascending Cholangitis
Rifaximin for Prevention of Recurrent Mild-to-moderate Ascending Cholangitis After Biliary-enteric Anastomosis
This single-center prospective randomized controlled trial plans to recruit 60 adult patients with recurrent ascending cholangitis after biliary-enteric anastomosis.
- Trial name
- NCT07895433
- Testing
- Rifaximin combined with standard care, Standard Care (in control arm)
- Volunteers
- 60 people
- Sponsor
- Ruijin Hospital
Patello-femoral Osteoarthritis
Hybrid Closed Wedge High Tibial Osteotomy
Osteoarthritis (OA) is the most prevalent condition of the knee joint. High tibial osteotomy (HTO) is an effective treatment for medial compartmental osteoarthritis (OA) of the knee with good clinical outcomes.
- Trial name
- NCT07907159
- Testing
- Hybrid Closed Wedge High Tibial Osteotomy
- Volunteers
- 20 people
- Sponsor
- Assiut University
Lipid Metabolism Disorders
Plasma Lipids-Dependent Vitamin E Metabolism During Dynamic Hyperlipidemia
Background: Obesity is known to lead to diseases such as diabetes and high cholesterol (or fats) in the blood (hyperlipidemia). But no one knows why.
- Trial name
- NCT07715890
- Testing
- High fat liquid shake
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Shoulder
Methylprednisolone Taper is an Effective Addition to Multimodal Pain Regimens After Rotator Cuff Repair
The use of Methylprednisolone Taper will be investigated in the setting of a Rotator Cuff Repair to determine if it will result in lower pain levels following surgery
- Trial name
- NCT07902843
- Testing
- Methylprednisolone taper
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Hawkins Foundation
Postoperative Pain
ESP Versus SPSIP Block for Pain Relief After Shoulder Arthroscopy
This study will compare two regional anesthesia techniques for pain relief after arthroscopic shoulder surgery: high thoracic erector spinae plane (ESP) block and serratus posterior superior intercostal plane (SPSIP) block.
- Trial name
- ESP-SPSIP (NCT07906392)
- Testing
- High Thoracic Erector Spinae Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ferit Yetik
HIV (Human Immunodeficiency Virus), Alcohol Misuse
PNF RCT to Decrease Alcohol Use and Increase HIV Prevention
Randomized controlled trial to test the preliminary efficacy and mediating mechanism of a personalized normative feedback intervention on behavioral intentions, heavy alcohol use, and HIV/STI prevention among adolescents and…
- Conditions
- HIV (Human Immunodeficiency Virus), Alcohol Misuse, STI
- Trial name
- NCT07731932
- Testing
- PNF - HIV norms, PNF - Alcohol use norms, PNF - HIV and alcohol use norms
- Where
- Uganda
- Volunteers
- 1,350 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Prostate Biopsy
A Multicenter, Randomized Controlled Superiority Trial Comparing Robotic-Assisted Versus Expert Cognitive Fusion Prostate Biopsy in Obese Men
The trial aims to find out if using a robotic system to help perform prostate biopsies is better than having a highly experienced doctor perform the biopsy by hand in men with a high Body Mass Index (BMI).
- Trial name
- NCT07600216
- Testing
- Robotic-Assisted Fusion Biopsy, Expert Cognitive Fusion Biopsy
- Where
- China
- Volunteers
- 570 people
- Sponsor
- Shanghai East Hospital
Systemic Lupus Erythematosus, Rheumatoid Arthritis (RA)
A Phase 1 Study of QLS2416 Injection in Participants With Autoimmune Diseases
The goal of this clinical trial is to evaluate the safety, tolerability, pharmacokinetics (PK), immunogenicity, and efficacy of QLS2416 injection in participants with autoimmune diseases (AID).
- Conditions
- Systemic Lupus Erythematosus, Rheumatoid Arthritis (RA), Primary Sjögren's Syndrome (pSS), Systemic Sclerosis (SSc)
- Trial name
- NCT07906145
- Testing
- QLS2416 Injection
- Volunteers
- 76 people
- Sponsor
- Shanghai Qilu Pharmaceutical Research and Development Center LTD
Neck Discomfort During Smartphone Use
Content Interest, Neck Posture, and Discomfort During Smartphone Use
This study will examine whether personal interest in smartphone video content changes neck discomfort, posture, and pressure pain sensitivity in young adults.
- Trial name
- NCT07907549
- Testing
- Preferred/High-Interest Smartphone Video Viewing, Neutral/Lower-Interest Smartphone Video Viewing
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Coronary Artery Disease, Left Ventricular Systolic Dysfunction
Preoperative Gastric Ultrasound and Left Ventricular Function in Coronary Artery Bypass Surgery
This study aims to investigate whether reduced heart function is associated with differences in stomach contents before elective coronary artery bypass graft (CABG) surgery.
- Conditions
- Coronary Artery Disease, Left Ventricular Systolic Dysfunction, Gastric Contents
- Trial name
- NCT07898215
- Testing
- Gastric Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Adiyaman University
Non Specific Neck Pain
Comparative Effects Of Exercises Targeting Upper Trapezius In Patients With Non Specific Neck Pain
Group A includes Myokinetic stretching, it is a form of myofascial release technique in which the taut band is released by incorporating active or passive stretching with movement until the intended release from the tight band is…
- Trial name
- NCT07907835
- Testing
- Myokinetic stretching, Integrated neuromuscular inhibition technique
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- University of Management and Technology Lahore
Post-Acute COVID-19 Syndrome
Phase I Open-Label Safety Trial of Pembrolizumab for Neurological Post- Acute Sequelae of SARS-CoV-2 (PD1-PASC I)
Background: SARS-CoV-2 is the virus that causes COVID-19. Some people who recover from an acute COVID-19 infection may continue to have symptoms that persist for months or years.
- Trial name
- NCT07388550
- Testing
- Keytruda
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Colorectal Neoplasms, Neoplasms
Hepatic Artery Infusion of Carfilzomib in Participants With Liver Metastatic Disease Previously Treated With Hepatic Artery Infusion Pump Therapy
Background: Cancers that begin in the colon, adrenal glands, or bile ducts may spread to the liver. These liver tumors are often treated using a hepatic artery infusion (HAI) pump.
- Conditions
- Colorectal Neoplasms, Neoplasms, Intrahepatic Cholangiocarcinoma, Adrenocortical Carcinoma
- Trial name
- NCT07715903
- Testing
- Carfilzomib
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Cancer Institute (NCI)
Pancreatic Cancer
A Study to Assess the Effect of Itraconazole on the Pharmacokinetics of HRS-4642 Following Intravenous Infusion in Healthy Participants
HRS-4642-103 is a single-center, single-arm, open-label, fixed-sequence study to investigate the effect of Itraconazole on the pharmacokinetics of HRS-4642 following intravenous infusion in healthy participants.
- Trial name
- NCT07906691
- Testing
- HRS4642, Itraconazole Capsules
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Shanghai Hengrui Pharmaceutical Co., Ltd.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.