Clinical trials: sponsored by Alcon Research
Dry Eye
Evaluation of Safety and Tolerability of Ocular Lubricants
The purpose of this study is to evaluate the safety profile of test formulations for an artificial tear product versus a comparator product.
- Trial name
- NCT05573360
- Testing
- NGF5-A test formulation, NGF4-B test formulation, NGF6-B test formulation
- Where
- 2 sites in Australia
- Volunteers
- 41 people
- Sponsor
- Alcon Research
Refractive Errors, Astigmatism
Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens
The purpose of this clinical study is to assess the clinical performance of an investigational toric soft contact lens compared to a commercially available toric contact lens in a crossover dispense trial when worn in a daily…
- Trial name
- NCT05211739
- Testing
- Lehfilcon A toric contact lenses, Comfilcon A toric contact lenses, CLEAR CARE
- Where
- 7 sites in United States
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Assessment of Two Daily Wear Reusable Soft Silicone Hydrogel Contact Lenses
The overall objective of this clinical study is to describe the clinical performance of the TOTAL30® soft contact lens compared to the ACUVUE® OASYS® with HYDRACLEAR PLUS (AOHP) soft contact lens in a daily wear modality.
- Trial name
- NCT05056987
- Testing
- Lehfilcon A contact lenses, Senofilcon A contact lenses, AOSEPT PLUS with HydraGlyde
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Refractive Ametropia
Assessment of an Investigational Frequent Replacement Silicone Hydrogel Lens
The purpose of this clinical trial is to evaluate the safety and performance of an investigational soft contact lens compared to a commercially available soft contact lens when worn in an extended wear modality.
- Trial name
- NCT04085328
- Testing
- LID015385 soft contact lenses, Comfilcon A soft contact lenses
- Where
- 42 sites in United States
- Volunteers
- 675 people
- Sponsor
- Alcon Research
Myopia
Daily Wear Comparison of Enhanced and Non-Enhanced Silicone Hydrogel Lenses
The purpose of this study is to compare an experimental contact lens with a currently marketed contact lens.
- Trial name
- NCT00813982
- Testing
- Lotrafilcon A Experimental Contact Lens, Lotrafilcon A Commercial Contact Lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Refractive Ametropia, Hyperopia
Air Optix Night and Day Aqua (AONDA) Retrospective Study 1
The purpose of this study is to assess long term performance and safety of AONDA in a real world setting when worn as daily wear or continuous wear for vision correction.
- Conditions
- Refractive Ametropia, Hyperopia, Myopia
- Trial name
- NCT05790928
- Testing
- Lotrafilcon A spherical contact lenses
- Where
- 4 sites in United States
- Volunteers
- 108 people
- Sponsor
- Alcon Research
Astigmatism, Refractive Errors
Clinical Comparison of Toric Contact Lenses Fit Characteristics
The purpose of this study is to compare the fit characteristics between four Alcon commercially available toric contact lenses.
- Trial name
- NCT05805345
- Testing
- Delefilcon A toric soft contact lens, Lehfilcon A toric soft contact lens, Lotrafilcon B toric soft contact lens
- Where
- 7 sites in United States
- Sponsor
- Alcon Research
Dry Eye
Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease
The purpose of this clinical trial is to investigate the efficacy of a single iLux® treatment in symptomatic CL wearers who have DED (according to the TFOS DEWS II diagnostic criteria), of the evaporative dry eye disease subtype…
- Trial name
- SHEEPDOG (NCT04159935)
- Testing
- iLux® system
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Aphakia, Presbyopia
Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL
The purpose of this clinical study is to assess the repeatability of objective refraction using auto refraction on subjects bilaterally implanted (implanted in both eyes) with the Fluid Accommodating IOL (FAIOL).
- Trial name
- NCT04330001
- Testing
- Alcon Fluid Accommodating Intraocular Lens, Top Con Autorefractor
- Where
- 2 sites in El Salvador, Panama
- Volunteers
- 99 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Contoura With Phorcides Compared to Wavefront Optimized LASIK
Comparing post-operative visual acuity and patient reported satisfaction between Contoura with Phorcides and WaveLight Wavefront Optimized.
- Trial name
- NCT05486546
- Testing
- Contoura with Phorcides, WaveLight Wavefront Optimized
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Daniel Terveen
Refractive Errors
Clinical Performance of Two Daily Disposable Soft Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1 contact lenses with Biotrue contact lenses.
- Trial name
- NCT05138783
- Testing
- Verofilcon A contact lenses, Nesofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 129 people
- Sponsor
- Alcon Research
Refractive Errors
Clinical Assessment of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of LID018869 soft contact with ACUVUE® OASYS with HYDRACLEAR® PLUS (AOHP) soft contact lenses over 30 days of daily wear.
- Trial name
- NCT05050578
- Testing
- Lehfilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 10 sites in United States
- Volunteers
- 166 people
- Sponsor
- Alcon Research
Contact Lens
Evaluation of Wear Experience With a Daily Disposable Contact Lens
To evaluate the wear experience of current two-week contact lens wearers after they have been fit into a daily disposable contact lens. This is a single arm, non-comparative study.
- Trial name
- NCT04296877
- Testing
- Daily Disposable Contact Lens
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Dry Eye Disease, Cataract
Systane Hydration in Subjects Undergoing Cataract Surgery
The primary objective of this study is to demonstrate reduced corneal staining with use of Systane Hydration among subjects with dry eye disease (DED) undergoing routine cataract removal and monofocal intraocular lens (IOL)…
- Trial name
- NCT05056233
- Testing
- Systane Hydration lubricant eye drops
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Alcon Research
Contact Lens
Wear Experience With Daily Contact Lenses Over a Long Day
This study is evaluating the wear experience of a daily contact lens after 10, 12, 14, and 16 hours of lens wear.
- Trial name
- NCT04535310
- Testing
- Precision1® Daily Disposable Contact Lens
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia
Evaluating the Initial Lens Handling Experience of Neophyte Contact Lens Wearers Fitted With Precision1 and 1-Day Acuvue Moist Contact Lenses
The initial subjecting handling experience of neophyte contact lens wearers with Precision1 will be compared to that with a daily disposable lens which mas been on the market for numerous years (1-Day ACUVUE Moist).
- Trial name
- SALUKI (NCT04205162)
- Testing
- Verafilcon A, Etafilcon A
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Evaluating the Performance of Precision1 Daily Disposable Contact Lens in a Group of Heavy Digital Device Users
The purpose of this study is to evaluate the performance of Precision1 DD CLs with regard to subjective symptoms (dryness, comfort, vision), lens fit and time to haze in CL wearers who identify themselves as heavy digital devices…
- Trial name
- PUG (NCT04201639)
- Testing
- Verofilcon A contact lenses
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of TOTAL30 contact lenses with Biofinity contact lenses over 30 days of daily wear.
- Trial name
- NCT04980456
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 14 sites in United States
- Volunteers
- 257 people
- Sponsor
- Alcon Research
Aphakia, Corneal Astigmatism
Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Toric IOL in an Asian Population
The purpose of this study is to evaluate the clinical performance of the ACRYSOF® IQ PanOptix® Toric Trifocal intraocular lens (IOL) when implanted in the eye following cataract removal in an Asian population.
- Trial name
- NCT04528069
- Testing
- ACRYSOF® IQ PanOptix® Toric Trifocal IOL, Cataract surgery
- Where
- 4 sites in Australia
- Volunteers
- 58 people
- Sponsor
- Alcon Research
Cataract, Astigmatism
AcrySof IQ Toric A-Code Post-Market Clinical Study
The purpose of this study is to clinically confirm the rotational stability of a modified AcrySof IQ toric intraocular lens (IOL) in a Japanese population.
- Trial name
- NCT03350503
- Testing
- AcrySof IQ Toric A-code IOL, Cataract surgery
- Where
- 4 sites in Japan
- Volunteers
- 125 people
- Sponsor
- Alcon Research