Clinical trials: sponsored by Emory University
Human Papilloma Virus, Human Immunodeficiency Virus
Use of ACU-D1 in HPV Associated Vulvar and Perianal Lesions in People With HIV
The goal of this study is to test the maximum tolerated dose of ACU-D1 in HIV-positive people with HPV-associated vulvar and perianal lesions.
- Conditions
- Human Papilloma Virus, Human Immunodeficiency Virus, Anal Intraepithelial Neoplasia, High-Grade Squamous Intraepithelial Lesions
- Trial name
- NCT06233331
- Testing
- Dose Level 1 ACU-D1 ointment, Dose Level 2 ACU-D1 ointment, Dose Level 3 ACU-D1 ointment
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Emory University
Cessation, Smoking
Efficacy of a Smoke-Free Homes Intervention
The purpose of this study is to test whether the integration of a smoke-free homes intervention into the clinical guidelines for tobacco cessation can encourage sustained smoking cessation in low-income primary care patients.
- Trial name
- SFH 5A RCT (NCT04547686)
- Testing
- Smoke-Free Homes Intervention, Quitline
- Where
- United States
- Volunteers
- 916 people
- Sponsor
- Emory University
Primary Graft Failure
REVEAL Biomarkers of Engraftment After Alternative Donor HSCT
The purpose of this study is to find new tests that could help determine if the newly infused bone marrow cells are growing well after bone marrow transplantation or if new bone marrow cells are needed.
- Trial name
- REVEAL (NCT03541889)
- Testing
- FLT imaging and TK1 blood measurements
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Oklahoma
PSA, Prostate Cancer
EDRN Prostate MRI Biomarker Study
The commercialization of MRI fusion biopsies has resulted in a dramatic increase in the use of MRI imaging for prostate cancer. How best to use MRI in the initial prostate biopsy setting given the availability of validated…
- Trial name
- P-MRI (NCT03784924)
- Testing
- MRI prostate
- Where
- United States
- Volunteers
- 950 people
- Sponsor
- University of Michigan
Radiation Exposure
Clinical Evaluation of a Novel Textile Radiation Protection Device
This study will use procedure-specific dosimetry to evaluate whether Texray's novel woven radiation protection fabric (HeadPeace and MindPeace) reduces occupational radiation dose to the head and thyroid of interventional…
- Trial name
- NCT07768605
- Testing
- Standard PPE, Texray PPE
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Emory University
Epilepsy, Depressive Symptoms
Electrophysiologic Mechanisms of Ketamine Antidepressant Response
This study aims to identify electrophysiologic biomarkers associated with antidepressant response to ketamine in adults with epilepsy undergoing clinically indicated stereo-electroencephalography (sEEG) monitoring who have at…
- Trial name
- Ketamine-sEEG (NCT07768618)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Emory University
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Diabetes Multimorbidity Typology, Trajectory, and Feasibility of an Audio Diary Mobile Application to Support Self-management
The goal of this clinical trial is to evaluate whether an audio diary mobile application (Fabla-diabetesMM) is feasible to use and may support self-management in older adults with type 1 or 2 diabetes and multimorbidity.
- Trial name
- NCT07474376
- Testing
- Fabla Mobile App
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
HIV Infection, HIV
Baricitinib Curative Repression of HIV-1
This study is being done to test whether a drug called baricitinib, which blocks specific causes of inflammation, affects HIV-1 viral rebound and viral load levels after HIV treatment is discontinued.
- Trial name
- NCT07209267
- Testing
- Antiretroviral Therapy (ART), Baricitinib (LY3009104) 2 mg, Baricitinib (LY3009104) 4 mg
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Emory University
Substance Use
Linking Individuals Needing Care for Substance Use Disorders to Peer Coaches & Across INcarceration Settings
The goal of this study is to learn whether a virtual peer recovery coach (PRC) intervention can improve engagement in addiction treatment among incarcerated adults with substance use disorders.
- Trial name
- LINCS UP & IN (NCT07563517)
- Testing
- Virtual Peer Recovery Coaching, Treatment as Usual
- Where
- 3 sites in United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Emory University
Stroke Hemorrhagic
Rapid Evacuation and Access of Cerebral Hemorrhage Trial
The main purpose of this study is to compare patients with a deep bleed in the brain undergoing surgery to patients receiving routine medical care.
- Trial name
- REACH (NCT06870812)
- Testing
- Surgical management, Medical Management
- Where
- 24 sites in United States
- Volunteers
- 600 people
- Sponsor
- Emory University
Breast Carcinoma
Mobile Health Patient Navigation for the Improvement of Screening and the Early Detection of Breast Cancer in Women Accessing Primary Care Clinics in Kenya
This clinical trial develops and studies how well mobile health (m-Health) patient navigation (PN) strategies work to improve screening and the early detection of breast cancer in women accessing primary care clinics in Kenya.
- Trial name
- NCT07764796
- Testing
- Best Practice, Discussion, Interview - Stakeholder
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Emory University
Nocturia, Insomnia
Multi-center Trial to Improve Nocturia and Sleep in Older Adults
The Multi-center Trial to Improve Nocturia and Sleep in Older Adults (MINT) study is a randomized trial to determine and assess the efficacy of integrated treatment of coexisting nocturia and insomnia, as well as explore the…
- Trial name
- MINT (NCT06110091)
- Testing
- Integrated Behavioral Therapy Program, Health Education Program
- Where
- 2 sites in United States
- Volunteers
- 192 people
- Sponsor
- Atlanta VA Medical Center
Congenital Heart Disease (CHD)
Cord Clamping Among Neonates With Congenital Heart Disease
The goal of this clinical trial is to compare 2 different timepoints for clamping the umbilical cord at birth for term-born infants with a prenatal diagnosis of congenital heart disease (CHD).
- Trial name
- CORD-CHD (NCT06153459)
- Testing
- Umbilical Cord Clamping at ~30 seconds, Umbilical Cord Clamping at ~120 seconds, Umbilical Cord Milking
- Where
- 21 sites in United States, Canada
- Volunteers
- 500 people
- Sponsor
- Carl Backes, MD
Cardiovascular Diseases
Web-based Physical Activity Intervention to Promote Physical Activity
In this study insufficiently active adults with obesity will be assigned to either the Physical Activity for The Heart (PATH) intervention or an attention control group.
- Trial name
- NCT05803304
- Testing
- PATH Intervention, Attention Control Intervention, Physical activity tracker
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Emory University
Respiratory Syncytial Virus (RSV)
Systems Biological Analysis of Immune Responses to RSV Vaccine
The purpose of this study is to characterize the immune response to the FDA-approved mRNA-based RSV vaccine in adults ≥60 years of age, using a systems biology approach.
- Trial name
- RSV SB (NCT07185399)
- Testing
- Moderna RSV vaccine
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Emory University
Peripheral Artery Disease (PAD)
Granulocyte-Macrophage Stimulating Factor (GM-CSF) in Peripheral Arterial Disease
Peripheral artery disease (PAD) is a disease in which plaque builds up in the arteries that carry blood to the head, organs, and limbs. PAD usually occurs in the arteries in the legs, but can affect any arteries.
- Trial name
- GPAD-3 (NCT03304821)
- Testing
- GM-CSF
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Emory University
Type 2 Diabetes
Changing the Natural History of Type 2 Diabetes ("CHANGE" Study)
Diabetes is a disorder of high blood glucose, that tends to get worse; over time, patients need more and more drugs. This pattern is caused by overwork of the body's insulin-producing β-cells, because patients' glucose levels are…
- Trial name
- CHANGE (NCT05040087)
- Testing
- Intensification of diabetes medication based largely on HbA1c levels, Intensification of diabetes medication based on glucose levels
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Foundation for Atlanta Veterans Education and Research, Inc.
Treatment Resistant Depression
Deep Brain Stimulation for Treatment Resistant Depression With the Medtronic Activa PC+S
The goal of this study is to use the Activa Primary Cell + Sensing (PC+S) device to study Latent Field Potential (LFP) in the brains of people with Treatment Resistant Depression (TRD) before and during active stimulation.
- Trial name
- NCT01984710
- Testing
- Medtronic Activa PC+S System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Cystic Fibrosis
Trikafta in Cystic Fibrosis Patients
This clinical study will enroll 42 participants without the F508del mutation, carrying partial function or N1303K mutations not approved for Trikafta, and who are not expected to be approved for CFTR modulator treatment in the…
- Trial name
- NCT03506061
- Testing
- Trikafta
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- Emory University
Mild Cognitive Impairment
Metformin in Alzheimer's Dementia Prevention
MAP will be a multi-center phase 2/3 1:1 randomized controlled trial (RCT) of long-acting metformin (reduced mass Glucophage XR) vs.
- Trial name
- MAP (NCT04098666)
- Testing
- extended release metformin
- Where
- 22 sites in United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Columbia University
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