Clinical trials: sponsored by Colgate Palmolive
Dental Caries
A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children
The objective of this study is to assess the safety and to evaluate the anti-caries efficacy of COL101 (arginine) non-fluoride dentifrices compared to a 0.24% sodium fluoride dentifrice in 10-14 year-old children over a one year…
- Trial name
- NCT04750902
- Testing
- 0.24% Sodium Fluoride Dentifrice, 1.5% Arginine Dentifrice, 4.0% Arginine Dentifrice
- Where
- 9 sites in United States, Puerto Rico
- Volunteers
- 2,025 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Cardiovascular Diseases, Diabetes Type 2
Baseline Oral Health Study: UnCoVer the Connections to General Health
Purpose: The Baseline Oral Health Health Study is a randomized controlled trial to evaluate the impact of regular, professional non-surgical Intensive Periodontal Therapy (scaling and root planing and optimal oral hygiene with…
- Trial name
- NCT04954313
- Testing
- Subgingival chlorhexidine irrigation, Dental Supplies, Periodonal Treatment
- Where
- 2 sites in United States
- Volunteers
- 786 people
- Sponsor
- University of North Carolina, Chapel Hill
Periodontitis
Effectiveness of a Triclosan Containing Toothpaste in Maintaining Periodontal Health in a Type 2 Diabetic Population
Clinical research study to determine the effectiveness of a triclosan/copolymer/fluoride toothpaste in maintaining periodontal health and therefore glycaemic control in a type 2 diabetic population.
- Trial name
- NCT00762762
- Testing
- Triclosan/copolymer/fluoride, Fluoride
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
COVID19, Coronavirus Infection
Antiviral Efficacy and Acceptability of Mouth Rinses for Inactivation of COVID-19
Subjects (125) will be randomized to one of five mouthrinses and will be asked to give a saliva sample immediately before and after a 30-60 second mouthwash.
- Conditions
- COVID19, Coronavirus Infection, SARS CoV-2 Infection
- Trial name
- COL (NCT04748783)
- Testing
- Water, Peroxyl, Periogard
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Plaque Induced Gingivitis
Induced Gingivitis & Intra-oral Imaging
Using an experimental, non-invasive intra-oral imaging device, this study evaluates the effects on the gingival tissue when oral hygiene is stopped in a section of the mouth for two weeks and gingivitis develops.
- Trial name
- NCT03750955
- Testing
- Plaque induced gingivitis, Oral hygiene maintenance
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Washington
Gingival Inflammation, Plaque
The Effectiveness of Brushing and Flossing Sequence on Control of Plaque and Gingival Inflammation
This study evaluates the effectiveness of brushing and flossing sequence in the control of dental plaque and gingival inflammation.
- Conditions
- Gingival Inflammation, Plaque, Gingival Bleeding, Plaque Control
- Trial name
- RCT (NCT03989427)
- Testing
- Brushing first and Flossing later (BF), Flossing first and Brushing later (FB)
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melaka Manipal Medical College
Quality of Life, Self Efficacy
Oral Health Education Interventions Among Seniors
The study aims to assess the efficacy of an oral health education group based activity versus an individual based oral health education activity in terms of changes in oral health related quality of life (OHRQoL), self-efficacy…
- Conditions
- Quality of Life, Self Efficacy, Knowledge
- Trial name
- NCT03301714
- Testing
- Oral Health Education
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Temple University
Survival of Bacteria on Skin After Using Different Soaps
Analysis of the Effect of Antimicrobial Soap on Bacterial Survival
This study will recruit up to 10 healthy volunteers. An avirulent strain of S. pyogenes will be applied to their forearms after washing each of their forearms with different types of soap, one with an antimicrobial compound, and…
- Trial name
- NCT02012348
- Testing
- Antibacterial soap with triclocarban, Antibacterial soap + benzalkonium chloride, Control soap
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Dental Plaque, Gingivitis
Six Month Plaque and Gingivitis Study Using Colgate Total Toothpaste
The objective of this randomized, single center, parallel clinical research study is to evaluate the comparative efficacy performance of three dentifrices -Colgate Total Toothpaste, Parodontax Toothpaste and Colgate Cavity…
- Trial name
- NCT02080273
- Testing
- Colgate Cavity Protection toothpaste, Colgate Total toothpaste, Parodontax toothpaste
- Where
- Thailand
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque and Gingivitis
The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis
This is a six (6) month, double-blind, parallel, controlled clinical trial utilizing one hundred and sixty (160) adults to evaluate the reduction of dental plaque and gingivitis.
- Trial name
- NCT02243046
- Testing
- Control toothpaste, Experimental toothpaste, Active Comparator
- Where
- Dominican Republic
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Oral Bacteria Levels in the Mouth
Clinical Investigation to Examine Toothpaste Effect on Oral Bacteria
The primary objective was to evaluate the antibacterial effects of two toothpastes containing 0.3% triclosan, 2% copolymer and 0.234% sodium fluoride in a silica base as compared to a control regular fluoride toothpaste on…
- Trial name
- NCT02194621
- Testing
- Total Flavor option 1, Total Flavor option 2
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
Clinical Study Comparing Dental Plaque and Gingivitis Reduction After Using One of Three Oral Hygiene Multi-component Regimens (Using of a Manual Toothbrush, a Toothpaste and a Mouthwash)
The objective of this clinical research study is to assess the efficacy of a commercially available triclosan/copolymer toothpaste compared to a commercially available oral hygiene multi-component regimen encompassing the use of…
- Trial name
- NCT02366689
- Testing
- Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride only toothpaste
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
The Clinical Investigation of Toothpaste as Compared to Toothpaste and Mouthwash in Reducing Plaque and Gingivitis: A Six-week Clinical Study in the US
The objective of this clinical research study is to evaluate clinical efficacy of Colgate Total Toothpaste as compared to Crest Pro-Health Toothpaste and Crest Pro-Health Mouthwash, and Crest Cavity Protection Toothpaste and…
- Trial name
- NCT02360995
- Testing
- Triclosan/fluoride toothpaste, stannous fluoride toothpaste, fluoride toothpaste
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
Compare Anti-inflammatory Dentifrices
Plaque induced gingivitis
- Trial name
- NCT00762528
- Testing
- Triclosan/Copolymer/fluoride toothpaste, Sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
Evaluate Inflammation Caused by Gingivitis in Adults
The purpose of this study is to compare the anti-inflammatory efficacy of a dentifrice
- Trial name
- NCT00941668
- Testing
- Triclosan/Copolymer/fluoride toothpaste, sodium monofluorophosphate toothpaste
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque, Gingivitis
The Clinical Efficacy of Three Oral Hygiene Regimens Using a Manual Toothbrush, Toothpaste and a Mouthwash in Controlling Dental Plaque and Gingivitis
The objective of this clinical research study is to assess the efficacy of three oral hygiene multi-component regimens encompassing the use of a manual toothbrush, toothpaste and a mouthwash in controlling established dental…
- Trial name
- NCT02193165
- Testing
- triclosan/fluoride toothpaste + cetylpyridinium chloride Mouthwash, stannous fluoride toothpaste + cetylpyridinium chloride Mouthwash, fluoride toothpaste + fluoride Mouthwash
- Where
- Puerto Rico
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Periodontal Disease
The Effect of Periodontal Treatment and the Use of Dentifrice on Glycaemic Control in Diabetics
To test effectiveness of dentifrice in maintaining periodontal health.
- Trial name
- NCT00763256
- Testing
- Triclosan, Fluoride, Fluoride
- Where
- Australia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Hypersensitivity
Clinical Efficacy of a Toothpaste on Hypersensitivity Reduction
Tooth sensitivity reduction after dentifrices use
- Trial name
- Yeaple (NCT01040169)
- Testing
- Arginine/Calcium Carbonate, Mint Prophy paste - Fluoride free
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Plaque
Clinical Study to Compare Dental Plaque Control
This clinical study was to evaluate the control of dental plaque formation after toothbrushing for 4 days with each of the 4 study toothpastes.
- Trial name
- NCT00758394
- Testing
- Fluoride, Triclosan/Fluoride
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Gingivitis
Comparative Efficacy of a Toothpaste That Reduces Plaque and Gingivitis
The objective of this study is to evaluate the performance of two toothpastes in controlling established gingivitis and dental plaque in adults.
- Trial name
- NCT00926328
- Testing
- Triclosan, fluoride, Fluoride
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive