Condition
Quality of Life Clinical Trials
Studies of quality of life, matched by condition name and medical subject headings. Start with those open to enrolment.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 2,616Dementia, Agitation
Virtual Reality to Advance Dementia Care and Quality of Life
The goal of this feasibility clinical trial is to learn whether supervised virtual reality (VR) sessions can be safely and practically provided to adults aged 55 years and older with moderate-to-severe dementia who experience…
- Conditions
- Dementia, Agitation, Behavioural and Psychological Symptoms of Dementia, Major Neurocognitive Disorder
- Trial name
- VR-Care (NCT07893678)
- Testing
- Supervised Virtual Reality Sessions
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dyssynergic Defecation
Effects of Connective Tissue Massage Plus Biofeedback for Dyssynergic Defecation
The goal of this randomized controlled clinical trial is to evaluate the effects of connective tissue massage (CTM) added to electromyographic biofeedback (EMG-BF) in adults with dyssynergic defecation (DD).
- Trial name
- NCT07890727
- Testing
- Electromyographic Biofeedback (EMG-BF), Connective Tissue Massage (CTM)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Selcuk University
Quality of Life
A Hybrid Effectiveness-Implementation and Cost-Utility Evaluation of a Support Programme for Informal Carers of People With Dementia in Primary Care (EsCuidar2)
The aim of this study is to evaluate whether the School of Caring programme improves quality of life and reduces caregiver burden among informal carers of people living with dementia.
- Trial name
- EsCuidar2 (NCT07861789)
- Testing
- School of Caring Programme
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Achondroplasia
Extension Study of Infigratinib in Children With Achondroplasia (ACH)
This is a Phase 2, multicenter, open-label, extension (OLE) study to evaluate the long-term safety, tolerability, and efficacy of infigratinib, an FGFR 1-3-selective tyrosine kinase inhibitor, in participants with ACH who…
- Trial name
- NCT05145010
- Testing
- Infigratinib
- Where
- 31 sites in United States, Argentina and 8 more
- Volunteers
- 325 people
- Sponsor
- QED Therapeutics, a BridgeBio company
Intractable Pain, Palliative Care
Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain
Background: Cancer-induced bone pain (CIBP) is common in people with cancer. Bone cancer can also lead to anxiety, depression, and reduced mobility and quality of life.
- Trial name
- NCT02522611
- Testing
- Resiniferatoxin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lymphoma
A Resilience-Based Approach to Improve Long-term Quality of Life in Post-treatment Lymphoma Survivorship
The goal of this trial is to learn if a resilience intervention can lead to improvements in lymphoma survivors' quality of life.
- Trial name
- NCT07013435
- Testing
- Health Education Program, SMART3RP-Lymphoma
- Where
- 3 sites in United States
- Volunteers
- 254 people
- Sponsor
- Massachusetts General Hospital
Multiple Sclerosis
The Effects of Synchronous and Asynchronous Pilates Training Based on Telerehabilitation on Core Stabilization, Balance, Cognitive Functions, and Quality of Life in Individuals With Multiple Sclerosis: A Single-Blind Randomized Controlled Trial
This study will compare live video-based and prerecorded video-based Pilates programs in 38 adults aged 18-65 years with multiple sclerosis. Participants will be randomly assigned to one of two groups.
- Trial name
- NCT07893925
- Testing
- Synchronous Telerehabilitation-Based Pilates, Asynchronous Telerehabilitation-Based Pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Yuzuncu Yil University
HIV (Human Immunodeficiency Virus)
Testing a Multi-Level Approach to Reduce Stigma for Women Living With HIV
This study will test two approaches to reduce HIV-related stigma and improve quality of life and viral suppression among women living with HIV in Dar es Salaam, Tanzania. Twenty health facilities will take part.
- Trial name
- NCT07881575
- Testing
- Labda Siku Moja, Total Facility Approach
- Where
- Tanzania
- Volunteers
- 680 people
- Sponsor
- RTI International
Parkinson Disease, Idiopathic
MediPD: An Online Mediterranean Diet Program for People Living With Parkinson's Disease
The aim of this pilot study is to assess whether an online Mediterranean diet programme called MediPD is acceptable and practical for people living with Parkinson's disease, and whether it can help them make and maintain changes…
- Trial name
- MediPD (NCT07838675)
- Testing
- MediPD Online Mediterranean Diet Program
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Queen's University, Belfast
Non-Puerperal Mastitis
Ablation Versus Non-ablation Strategies for Non-puerperal Mastitis: A Prospective Real-world Registry Study
The goal of this prospective registry cohort study is to evaluate the efficacy and quality-of-life impact of ablation therapy in patients with non-puerperal mastitis.
- Trial name
- NCT07894614
- Testing
- Ablation, Observation
- Where
- China
- Volunteers
- 340 people
- Sponsor
- Song Hongping
Completed, with results posted
All 645Chronic Kidney Diseases
Helping Relationships From Significant Others on Healthy Lifestyle and Quality of Life Among Patients With CKD( CKD Lifestyle)
This clinical trial aims to evaluate the effectiveness of a helping relationships intervention program for patients with chronic kidney disease (CKD).
- Trial name
- CKD lifestyle (NCT02076256)
- Testing
- helping relationships
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Cheng Kung University
Cancer, Quality of Life
The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer
Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer
- Conditions
- Cancer, Quality of Life, Anxiety, Depression
- Trial name
- PRISM-AC (NCT03668223)
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- 5 sites in United States
- Volunteers
- 269 people
- Sponsor
- Dana-Farber Cancer Institute
Psychological Distress
Ensemble Programme an Early Intervention for Informal Caregivers of Psychiatric Patients
This study focuses on the difficulties of maintaining optimal psychological health and quality of life for caregivers in adult psychiatry while they play an important role in helping patients with severe psychiatric disorders.
- Trial name
- Ensemble (NCT04020497)
- Testing
- Ensemble programme, SAU
- Where
- Switzerland
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Institut et Haute Ecole de la Santé la Source
Neoplasms, Bereavement
ERANet-LAC CODE: International Care Of the Dying Evaluation
Providing high quality care for dying patients and their families is very important. One way one can assess the care provided is to ask bereaved relatives to complete a questionnaire after their family member has died.
- Conditions
- Neoplasms, Bereavement, Quality of Life
- Trial name
- NCT03566732
- Where
- 20 sites in Argentina, Brazil and 5 more
- Volunteers
- 914 people
- Sponsor
- University of Bergen
Localized Prostate Cancer
Study of the Efficacy, Safety and Quality of Life After TOOKAD® Soluble (VTP) for Intermediate Risk Prostate Cancer.
Single center, single-arm, open-label, 60-month follow-up phase IIb clinical trial. Men with localized prostate cancer will receive TOOKAD® Soluble VTP under general anesthesia.
- Trial name
- NCT03315754
- Testing
- TOOKAD Soluble 4 mg/kg
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Steba Biotech S.A.