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Condition

Sarcopenia Clinical Trials

Studies of sarcopenia, matched by condition name and medical subject headings. Start with those open to enrolment.

1,417 registered studies

In numbers

Open to volunteers
360
Active
415
With results posted
57
All registered
1,417

Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.

Open to volunteers

All 360
  • Insomnia Chronic, Hypnotics and Sedatives

    Physical Activity Interventions for Sleep Improvement and Sedative-Hypnotic Reduction in Middle-Aged and Older Adults: Investigating the Role of Sarcopenia

    • Enrolling by invitation
    • Age: 50 years and older
    • Lifestyle or therapy programme

    Background: The prevalence of sedative-hypnotic use among middle-aged and older adults in Taiwan has continued to rise, highlighting the need to better understand the underlying factors contributing to sleep disturbances and…

    Conditions
    Insomnia Chronic, Hypnotics and Sedatives, Physical Activities
    Trial name
    NCT07896603
    Testing
    resistance training, Relaxation training
    Where
    Taiwan
    Volunteers
    40 people
    Sponsor
    Chang Gung Memorial Hospital
    Can I take part? NCT07896603
  • Frailty, Sarcopenia

    PROfiles of FGF-19 Post-prandial Secretion in Older Adults With Frailty and Without Frailty

    • Not yet recruiting
    • Age: 70 years and older

    Fibroblast Growth Factor 19 (FGF-19) is an intestinal hormone secreted in the post-prandial state, whose primary role is to inhibit bile acid synthesis in the liver.

    Trial name
    PRO-FGF (NCT07893665)
    Testing
    FLEXMEAL : post-prandial blood sampling
    Where
    France
    Volunteers
    30 people
    Sponsor
    Hospices Civils de Lyon
    Can I take part? PRO-FGF
  • Colorectal Cancer, Colorectal Neoplasms

    Resistance vs Aerobic Prehabilitation Before Colorectal Cancer Surgery

    • Recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    The goal of this clinical trial is to learn which type of exercise before surgery best reduces complications after colorectal surgery in adults with colorectal cancer or precancerous lesions.

    Conditions
    Colorectal Cancer, Colorectal Neoplasms, Postoperative Complications
    Trial name
    NCT07896174
    Testing
    Resistance Training Prehabilitation, Aerobic Training Prehabilitation, Standard Trimodal Care
    Where
    Hungary
    Volunteers
    480 people
    Sponsor
    Semmelweis University
    Can I take part? NCT07896174
  • Frailty/Sarcopenia, Frailty in Older Adults

    Effects of a Community-based Multicomponent Physical Exercise Program on Physical Function, Frailty, and Sarcopenia in Older Adults From the Municipality of Santoña: a Quasi-experimental Study.

    • Recruiting
    • Age: 65 years and older
    • Lifestyle or therapy programme

    This study evaluates the effects of a community-based multicomponent exercise program on physical function, frailty, and sarcopenia in older adults living in the municipality of Santoña (Cantabria, Spain).

    Conditions
    Frailty/Sarcopenia, Frailty in Older Adults, Sarcopenia
    Trial name
    NCT07732478
    Testing
    Multicomponent Exercise Program (Vivifrail-based)
    Where
    Spain
    Volunteers
    300 people
    Sponsor
    Universidad de Granada
    Can I take part? NCT07732478
  • Muscle Adaptation, Body Composition

    Creatine and Muscle Health in Madrid's Walking Footballers.

    • Not yet recruiting
    • Age: 50 years and older

    Healthy aging requires effective, accessible, and sustainable interventions capable of preserving functional capacity and preventing age-related decline.

    Conditions
    Muscle Adaptation, Body Composition, Physical Activity in Adults
    Trial name
    MyoCreaWalk (NCT07891936)
    Testing
    Monohydrate Creatine supplementation during Walking Football training
    Volunteers
    20 people, healthy volunteers welcome
    Sponsor
    Universidad Europea de Madrid
    Can I take part? MyoCreaWalk
  • Sarcopenia, Acute Stroke

    Sarcopenia in Acute Ischemic Stroke

    • Recruiting
    • Age: 50 years and older
    • Observational study

    The objective of this observational study is to determine the prevalence of sarcopenia in patients aged 50 years and older with acute ischemic stroke, to characterize its trajectory during the acute phase using instrumental…

    Trial name
    NCT07764172
    Where
    Russia
    Volunteers
    400 people
    Sponsor
    University Clinical Hospital na V.V.Vinogradov (branch of RUDN university na Patrice Lumumba)
    Can I take part? NCT07764172
  • Colorectal Cancer Survivors

    Low Load Blood Flow Restriction Resistance Training in Colorectal Cancer Related Sarcopenia

    • Recruiting
    • Age: 40 to 59 years
    • Lifestyle or therapy programme

    PURPOSE: To investigate the effects of low-load resistance training combined with blood flow restriction on muscle strength, functional performance, and cancer-related fatigue in colorectal cancer survivors with probable…

    Trial name
    NCT07874035
    Testing
    Low load blood flow restriction resistance training, Low load resistance training without Blood Flow Restriction
    Where
    Egypt
    Volunteers
    54 people
    Sponsor
    Ahmed Adel Ahmed Elsayed Ali Radwan
    Can I take part? NCT07874035
  • Sarcopenia

    Yijinjing Exercise for Musculoskeletal Health in Adults With Sarcopenia

    • Not yet recruiting
    • Age: 50 years and older
    • Lifestyle or therapy programme

    Sarcopenia is a condition involving loss of muscle mass and strength that can make walking and other daily activities more difficult.

    Trial name
    NCT07871240
    Testing
    Modified Yijinjing Exercise, Progressive Resistance Training, Dietary Counseling and Health Education
    Where
    6 sites in China
    Volunteers
    240 people
    Sponsor
    Beijing Hospital of Traditional Chinese Medicine
    Can I take part? NCT07871240
  • PDAC, Pancreas Adenocarcinoma (MSI-H)

    Targeted Nutritional Intervention (HMB, Arginine, Glutamine) in Patients With Pancreatic Cancer

    • Not yet recruiting
    • Age: 18 years and older
    • Pill or oral medicine

    Pancreatic ductal adenocarcinoma (PDAC) is frequently associated with cancer cachexia, a condition characterized by progressive loss of skeletal muscle mass and strength driven by systemic inflammation.

    Trial name
    NUTRI-MYO (NCT07883161)
    Testing
    HMB / L-Arginine / L-Glutamine oral nutritional mixture, Standard Dietary Counseling
    Where
    Italy
    Volunteers
    24 people
    Sponsor
    Fondazione Policlinico Universitario Agostino Gemelli IRCCS
    Can I take part? NUTRI-MYO
  • Sarcopenia, Breast Cancer

    Exercise Intervention for Breast Cancer Patients With Sarcopenia

    • Not yet recruiting
    • Age: 18 years and older
    • Lifestyle or therapy programme

    Sarcopenia is a common yet underrecognized complication in breast cancer survivors during rehabilitation, characterized by loss of muscle mass, reduced muscle strength, and impaired physical function, which adversely affects…

    Trial name
    EX-BCSarc (NCT07732101)
    Testing
    "Exercise for Muscle Health" Program
    Where
    China
    Volunteers
    104 people
    Sponsor
    Capital Medical University
    Can I take part? EX-BCSarc

Completed, with results posted

All 54
  • Sarcopenia, Osteoporosis

    Muscle Impact of Treating Osteoporosis

    • Completed
    • Age: 65 years and older
    • Phase 4
    • Results posted

    Osteosarcopenia is a geriatric musculoskeletal syndrome characterized by co-existence of osteoporosis and sarcopenia (low skeletal muscle mass, strength, and/or functional capacity).

    Trial name
    MITO (NCT05666310)
    Testing
    Denosumab, Zoledronic Acid
    Where
    United States
    Volunteers
    20 people
    Sponsor
    Nami Safai Haeri
    Can I take part? MITO
  • Sarcopenia, High Blood Pressure

    The Impact of a Resistance Training Intervention on Blood Pressure Control in Older Adults With Sarcopenia

    • Completed
    • Age: 60 years and older
    • Lifestyle or therapy programme
    • Results posted

    Current prevention and treatment of high blood pressure (BP) in sarcopenia, by non-pharmacological approaches remain limited and are far from optimal.

    Conditions
    Sarcopenia, High Blood Pressure, Hypertension
    Trial name
    INERTIA (NCT04255745)
    Testing
    progressive resistance training
    Where
    United States
    Volunteers
    77 people, healthy volunteers welcome
    Sponsor
    University of Illinois at Chicago
    Can I take part? INERTIA
  • Cirrhosis, Aerobic Exercises

    The Efficacy of Aerobic Exercise Training on ANS and Endothelial Function in Compensated Cirrhosis

    • Completed
    • Age: 45 to 75 years
    • Lifestyle or therapy programme
    • Results posted

    The goal of this randomized controlled trial is to investigate whether a 16-week structured aerobic exercise program combined with nutritional consultation can improve autonomic and endothelial function in patients with…

    Conditions
    Cirrhosis, Aerobic Exercises, Lifestyle Modification, Endothelial Function
    Trial name
    NCT06288828
    Testing
    Aerobic exercise + Nutrition consultant, Nutrition consultant
    Where
    Thailand
    Volunteers
    50 people
    Sponsor
    King Chulalongkorn Memorial Hospital
    Can I take part? NCT06288828
  • Sarcopenia, Inflammation

    Effect of Fermented Milk Containing Lactobacillus Casei Strain Shirota in Sarcopenia Elderly

    • Completed
    • Age: 65 to 85 years
    • Results posted

    Sarcopenia, which refers to the progressive loss of skeletal muscle mass and strength, shares many characteristics with other disease states typically associated with risks of falling and fracture, including osteoporosis…

    Conditions
    Sarcopenia, Inflammation, Aging
    Trial name
    NCT04985877
    Testing
    Yakult 300 LIGHT Fermented Milk
    Where
    3 sites in Taiwan
    Volunteers
    132 people, healthy volunteers welcome
    Sponsor
    Taipei Medical University
    Can I take part? NCT04985877
  • Sarcopenia, Diabetes Mellitus

    Identifying Therapeutic Targets of Accelerated Sarcopenia

    • Completed
    • Age: 60 to 85 years
    • Lifestyle or therapy programme
    • Results posted

    The proposed research is designed to identify the mechanisms that can accelerate loss of muscle size, strength and physical function in type 2 diabetes and with hospitalization in older persons.

    Conditions
    Sarcopenia, Diabetes Mellitus, Aging
    Trial name
    NCT03118050
    Testing
    Resistance exercise training, Bed rest, Intensive physical therapy
    Where
    United States
    Volunteers
    95 people, healthy volunteers welcome
    Sponsor
    The University of Texas Medical Branch, Galveston

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