Research institution
Dartmouth-Hitchcock Medical Center Clinical Trials
Studies where Dartmouth-Hitchcock Medical Center is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 70Osteoarthritis of the Knee
The Feasibility of a Virtual/Home-based OA Treatment Program in Older Adults With OA and Multimorbidity
Knee Osteoarthritis is one of the most common causes of chronic joint pain. Although clinical guidelines recommend weight loss and regular physical activity as first line treatments this can be difficult for patients to do.
- Trial name
- NCT07921563
- Testing
- Home-based exercise and weight management program
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Weight Bias
Digital SSI to Reduce IWS
The purpose of this research is to evaluate a brief digital single-session intervention designed to reduce internalized weight stigma among Dartmouth Health Weight Center patients.
- Trial name
- NCT07911462
- Testing
- Psychoeducation, Self-compassion, Body functionality
- Volunteers
- 610 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Epilepsy, Cognitive Dysfunction, Cognitive Disorder
HOBSCOTCH-YOUTH and Young Adults
The goal of this clinical trial is to learn more about the home-based epilepsy self-management program, HOBSCOTCH, for improving cognitive function (thinking and memory) and quality of life specifically in young adults, ages 18 …
- Conditions
- Epilepsy, Cognitive Dysfunction, Cognitive Disorder, Memory and Thinking Problems
- Trial name
- NCT07735715
- Testing
- HOBSCOTCH/HOBSCOTCH-YOUTH
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Multiple Sclerosis, Cognitive Dysfunction
HOBSCOTCH-MS-Efficacy Trial
The purpose of this study is to assess the ability of the home-based intervention, HOBSCOTCH-MS to improve the quality of life and cognitive function in Service Members, Veterans and civilians who have multiple sclerosis with…
- Conditions
- Multiple Sclerosis, Cognitive Dysfunction, Memory Disorders, Memory Impairment
- Trial name
- NCT06951919
- Testing
- Home Based Self- management and Cognitive Training Changes lives in Multiple Sclerosis (HOBSCOTCH-MS)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Breast Cancer
Pilot SMART of a Remotely Delivered, Physical Activity Intervention for Breast Cancer Survivors
The goal of this clinical trial is to evaluate the feasibility of randomizing participants to a "step-up" intervention pathway when they perform <150 minutes of MVPA at the 6-week data collection burst.
- Trial name
- NCT07706556
- Testing
- Affect-based Exercise Prescription, Effort-based exercise prescription, Standard Exercise Promotion Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Severe Mental Illness
Supporting Older Adults Remotely
The Supporting Older Adults Remotely (SOAR) study is a randomized controlled trial evaluating a 12-week, telephone-delivered peer support intervention for adults age 50 and older with serious mental illness who live in supportive…
- Trial name
- SOAR (NCT07878169)
- Testing
- Supporting Older Adults Remotely (SOAR), Peer support as usual
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Endonasal Surgery, Endoscopic Sinus Surgery
In Vivo Imaging of the Olfactory Epithelium Using Confocal Laser Endomicroscopy
This research is being done to better characterize the part of the nose that helps people smell. Currently, the only ways to study smell loss mostly rely on how people report it, rather than being able to see the underlying…
- Conditions
- Endonasal Surgery, Endoscopic Sinus Surgery, Olfactory Dysfunction
- Trial name
- NCT07546617
- Testing
- CONVIVO system, Fluorescein injection, USP 10%
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Mild Cognitive Impairment
MCI Speech in Noise
The purpose of this study is to determine whether people with MCI (Mild Cognitive Impairment) and healthy comparison subjects differ with respect to their ability to hear soft sounds and how their brain understands and processes…
- Trial name
- NCT06102486
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Colorectal Polyp, Colorectal Neoplasms
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
This is a multi-site comparative effectiveness randomized controlled trial (RCT) comparing annual fecal immunochemical testing (FIT) and colonoscopy for post-polypectomy surveillance among adults aged 65-82 with a history of…
- Conditions
- Colorectal Polyp, Colorectal Neoplasms, Colorectal Adenoma, Colorectal Cancer
- Trial name
- COOP (NCT05612347)
- Testing
- FIT, Colonoscopy
- Where
- 24 sites in United States, Canada
- Volunteers
- 6,434 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Depression - Major Depressive Disorder
iPath for CP Pilot
Depression is a significant problem in care partners of people living with dementia; despite the expansion of options for accessing evidence-based treatments, most care partners of people living with dementia are not screened for…
- Trial name
- care partners (NCT07631247)
- Testing
- depression app for care partners of persons with dementia
- Volunteers
- 15 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Completed, with results posted
All 111Metastatic Breast Cancer
ER Reactivation Therapy for Breast Cancer
Before anti-estrogens such as tamoxifen were developed to treat estrogen receptor (ER)-positive breast cancer, high-dose estrogen therapies were used.
- Trial name
- POLLY (NCT02188745)
- Testing
- 17B-estradiol, Letrozole, Anastrozole
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia
Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' Expression
The standard Johns Hopkins' regimen will be used in study subjects, with the use of donor peripheral blood stem cells, rather than marrow.
- Conditions
- Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia, Chronic Myeloid Leukemia, Myelodysplasia
- Trial name
- NCT03480360
- Testing
- Cyclophosphamide, Fludarabine, Total Body Irradiation
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cancer
Education About Health and Cancer Study
This study investigates different ways to educate rural residents living in New Hampshire and Vermont about cancer research studies and clinical trials to increase knowledge of, increase positive attitudes toward, and encourage…
- Trial name
- NCT04409782
- Testing
- Online educational video
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Cancer, Colorectal Cancer
Screen to Save 2: Rural Cancer Screening Educational Intervention
The purpose of this study is to help the Dartmouth Cancer Center and the National Cancer Institute understand how to educate people about cancer screening.
- Trial name
- NCT04414306
- Testing
- Online educational video and website module
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Frostbite, Frostbite of Hand
Multicenter Sous Vide Frostbite
The purpose of this study is to determine the efficacy of using sous vide devices for heating and maintaining the circulating warm water bath used in the rewarming of acute frostbite.
- Conditions
- Frostbite, Frostbite of Hand, Frostbite of Foot
- Trial name
- NCT05280301
- Testing
- Sous Vide Device (SVD)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Dartmouth-Hitchcock Medical Center