Research institution
Fujian Medical University Clinical Trials
Studies where Fujian Medical University is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 136Breast Cancer
Internal Mammary Lymph Nodes Irradiation in High-risk Breast Cancer After Neoadjuvant Chemotherapy
The aim of this study is to explore the impact of internal mammary nodal irradiation on disease-free survival in high-risk breast cancer patients (ypN+or supra/subclavicular lymph node positive) after neoadjuvant chemotherapy.
- Trial name
- NCT06559696
- Testing
- internal mammary nodal irradiation, No internal mammary node irradiation
- Where
- China
- Volunteers
- 722 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Esophageal Squamous Cell Carcinoma, Immunotherapy
Adebrelimab ±Induction Chemotherapy Followed by Concurrent Chemoradiotherapy for Unresectable Locally Advanced ESCC
To evaluate the efficacy and safety of adebrelimab with or without induction chemotherapy followed by concurrent chemoradiotherapy for unresectable locally advanced esophageal squamous cell carcinoma
- Conditions
- Esophageal Squamous Cell Carcinoma, Immunotherapy, Biomarkers
- Trial name
- RICE (NCT06510660)
- Testing
- adebrelimab
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Fujian Medical University Union Hospital
Acute Lung Injury, Prevention
PirfenidoneVsPlacebo as Prophylaxis Against Acute Radiation-induced Lung Injury Following HFRT in Breast Cancer Patients
The incidence of chest CT manifestations of lung injury after radiotherapy for breast cancer is more than 50%. Although the prognosis and quality of life of patients are rarely affected, it is still necessary to prevent the…
- Trial name
- NCT05704166
- Where
- China
- Volunteers
- 214 people
- Sponsor
- Fujian Medical University Union Hospital
Esophageal Squamous Cell Carcinoma
Biomarker Based Neoadjuvant Strategies for Locally Advanced Resectable ESCC
This study aims to evaluate the impact of the neoadjuvant treatment strategy based on CPS score on the pathological complete response (pCR) rate in patients with resectable locally advanced esophageal cancer.
- Trial name
- ESCC (NCT06601309)
- Testing
- Serplulimab, Paclitaxel+Cisplatin (Neoadjuvant Chemotherapy), Paclitaxel+Cisplatin(Concurrent Chemoradiotherapy)
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Fujian Medical University Union Hospital
Acute Ischemic Stroke
Tenecteplase in Acute Ischemic Stroke Under Different Transfer Models
This prospective, multicenter, observational cohort study aims to evaluate the safety and effectiveness of intravenous tenecteplase (rhTNK-tPA) in patients with acute ischemic stroke managed under different transfer models.
- Trial name
- NCT07897955
- Testing
- tenecteplase
- Where
- 6 sites in China
- Volunteers
- 2,000 people
- Sponsor
- Fujian Medical University Union Hospital
Gastroenteropancreatic Neuroendocrine Tumors
Incremental Value of Delayed 68Ga-DOTATATE PET/MR in the Detection of Liver Metastases
68-Ga-DOTATATE is a radiotracer targeting somatostatin receptors (SSTR). In this study, we investigated the diagnostic efficacy of delayed ^68^Ga-DOTATATE PET/MR in patients with gastroenteropancreatic neuroendocrine tumors…
- Trial name
- NCT07898904
- Where
- China
- Volunteers
- 46 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Ischemic Stroke, Post-stroke Dysphagia
EEG Feedback-Based Vagus Nerve Stimulation for Post-Stroke Dysphagia
The goal of this clinical trial is to learn if electroencephalogram (EEG) biofeedback-guided transcutaneous auricular vagus nerve stimulation (taVNS) works to treat swallowing difficulties (dysphagia) in adults after a stroke.
- Conditions
- Ischemic Stroke, Post-stroke Dysphagia, Swallowing Disorders
- Trial name
- NCT07894315
- Testing
- EEG Biofeedback-Guided taVNS, Conventional taVNS
- Where
- 6 sites in China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Dementia, Alzheimer Dementia (AD)
Fuzhou Aging Brain Health Initiative
The goal of this observational study is to learn about the pathophysiological characterization and evolutionary patterns of Alzheimer's disease (AD) in older adults in Fujian Province, China.
- Conditions
- Dementia, Alzheimer Dementia (AD), Mild Cognitive Impairment (MCI), Subjective Cognitive Decline (SCD)
- Trial name
- FAITH (NCT07891429)
- Testing
- Fluids biomarker and neuroimaging of AD diagnosis
- Where
- 4 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University Union Hospital
Cardiac Surgery With Cardiopulmonary Bypass, Postoperative Delirium
Mechanisms and Intervention Strategies of Perioperative Glycemic Variability on Postoperative Delirium
Delirium is a sudden change in attention, thinking, and awareness that can occur after heart surgery. It may slow recovery and is associated with longer hospital stays and poorer health outcomes.
- Trial name
- NCT07893353
- Testing
- Intranasal insulin-20U, Intranasal insulin-40U, Intranasal Saline
- Where
- China
- Volunteers
- 225 people
- Sponsor
- Fujian Medical University Union Hospital
Heart Valve Surgery, Acute Kidney Injury
Effects of Remote Ischemic Preconditioning at Different Time Phases in Patients Undergoing Heart Valve Surgery
Patients undergoing heart valve surgery require cardiopulmonary bypass, a procedure that can lead to a temporary reduction in blood flow to major organs and subsequent ischemia-reperfusion injury, thereby triggering postoperative…
- Trial name
- NCT07888634
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Fujian Medical University Union Hospital
Completed, with results posted
All 1Cardiovascular Disease
A New Operation for the Treatment for Long-standing Atrial Fibrillation
Atrial fibrillation(AF) often occurs in patients with mitral valve disease. Both mitral replacement and mitral valve plasty are the effective methods to the mitral valve disease.
- Trial name
- ANOLAF (NCT03347695)
- Testing
- Left Atrial Geometric Volume Reduction, Pulmonary Vein Island Isolation and Left Appendage Base Closure(selected patients), Left Atrial Geometric Volume Reduction, Pulmonary Vein Island Isolation and Left Appendage Base Closure
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Fujian Medical University