Research institution
Shanghai Mental Health Center Clinical Trials
Studies where Shanghai Mental Health Center is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 68Non-suicidal Self-injury (NSSI)
Efficacy of Triple-daily 15mA tACS on Adolescent NSSI
This study aims to evaluate the clinical effectiveness of triple-daily 15 mA tACS stimulation in adolescents with Nonsuicidal Self-Injury (NSSI) by comparing the outcomes of active versus sham tACS interventions.
- Trial name
- NCT06919432
- Testing
- Active-tACS (Nexalin Technology, Inc., Houston, TX, USA)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Shanghai Mental Health Center
Alcohol Use Disorder (AUD)
High Intensity Alternating Current Stimulation as a Neuromodulation Therapy for Alcohol Use Disorder: A Pilot Study
This one-arm pilot study aims to evaluate the preliminary clinical, behavioral, and neurophysiological effects of high-intensity transcranial alternating current stimulation (HI-tACS) in individuals with alcohol use disorder…
- Trial name
- HITACS-AUD (NCT07227545)
- Testing
- HI-tACS
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Insomnia
A Multicenter Observational Study of Daridorexant in the Treatment of Insomnia
This study aims to evaluate the effectiveness and safety of daridorexant, a novel dual orexin receptor antagonist (DORA), in patients with insomnia.
- Trial name
- NCT07847021
- Testing
- Daridorexant 50 mg
- Where
- 25 sites in China
- Volunteers
- 500 people
- Sponsor
- Shanghai Mental Health Center
Obsessive - Compulsive Disorder
Cohort Study of Obsessive-Compulsive Disorder
This study will establish a standardized, multi-dimensional prospective longitudinal cohort for obsessive-compulsive disorder. It seeks to explore differences in symptom trajectories, functional trajectories, treatment responses…
- Trial name
- NCT07822516
- Volunteers
- 500 people
- Sponsor
- Shanghai Mental Health Center
Obsessive Compulsive Disorder (OCD)
Transcutaneous Electrical Acupoint Stimulation Combined With Exposure and Response Prevention in the Treatment of Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial
Obsessive-compulsive disorder is a chronic and disabling mental disorder. Among them, 40-60% of obsessive-compulsive disorder patients do not respond to the current first-line drug treatment and/or psychological therapy.
- Trial name
- NCT07811778
- Testing
- Exposure and Response Prevention, Active Transcutaneous Acupoint Electrical Stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Mental Health Center
SCHIZOPHRENIA 1 (Disorder)
Multi-target TMS for Schizophrenia Negative Symptoms
This randomized controlled trial (RCT) is the first to evaluate the efficacy and safety of a multi-target TMS protocol targeting the right orbitofrontal cortex (R-OFC), left dorsolateral prefrontal cortex (L-DLPFC), and left…
- Trial name
- NCT07559084
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Shanghai Mental Health Center
Alcohol Use Disorder
HD-tACS for Alcohol Use Disorder
This study aims to systematically explore the effectiveness of accelerated HD-tACS in treating AUD, particularly its efficacy in reducing alcohol craving and preventing relapse in AUD patients.
- Trial name
- NCT07808190
- Testing
- HD-tACS
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Shanghai Mental Health Center
Depression Disorder, Chronic Pain
Transcranial Electrical Stimulation for Comorbid Depression and Chronic Pain
The goal of this clinical trial is to learn if active transcranial alternating current stimulation (tACS) and transcranial direct current stimulation (tDCS) can improve pain symptoms in patients with major depressive disorder…
- Trial name
- NCT07334561
- Testing
- tDCS, alpha-tACS
- Where
- 2 sites in China
- Volunteers
- 160 people
- Sponsor
- Shanghai Mental Health Center
Amphetamine Use Disorders
Closed-loop tTIS Targeted of the Nac as an Intervention for MUD Patients
Closed-loop transcranial temporal interference stimulation (tTIS) targeting the nucleus accumbens may modulate abnormal neural responses to drug-related cues in individuals with methamphetamine use disorder (MUD), thereby…
- Trial name
- NCT07802223
- Testing
- Temporal Interference Stimulation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Shanghai Mental Health Center
Treatment-Resistant Major Depressive Disorder, Major Depressive Disorder
Precision Closed-loop Brain-Computer Interface Neuromodulation for Treatment-Resistant Depression
The goal of this clinical trial is to evaluate whether precision closed-loop neuromodulation treatments can improve depressive symptoms and daily functioning in people with treatment-resistant major depressive disorder (TRD).
- Trial name
- NCT07783906
- Testing
- Closed-loop Deep Brain Stimulation (DBS), Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)
- Volunteers
- 70 people
- Sponsor
- Shanghai Mental Health Center
Completed, with results posted
All 3Anxiety Symptoms, Anxiety Disorders
TMS for Anxiety and Trauma-related Disorders
The present pilot study will apply accelerated intermittent theta burst stimulation (aiTBS) to a novel transcranial magnetic stimulation (TMS) target for anxiety derived via causal network mapping.
- Trial name
- NCT06475040
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shanghai Mental Health Center
Obese, Cigarette-smoking
Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia
The purpose of this research is to observe the efficacy of Naltrexone and Bupropion combination on weight loss and smoking cessation from baseline to week 24 compare to placebo.
- Conditions
- Obese, Cigarette-smoking, Schizophrenia
- Trial name
- NCT02736474
- Testing
- Naltrexone, Bupropion
- Volunteers
- 22 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia
Study of Repetitive Transcranial Magnetic Stimulation in the Treatment of Cognitive Impairment in Schizophrenia
1. Exploration of repetitive transcranial magnetic stimulation（rTMS）on working memory and cognitive impairment symptoms of schizophrenia treatment and mechanism. 2.
- Trial name
- NCT01940939
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Shanghai Mental Health Center