Research institution
Tongji Hospital Clinical Trials
Studies where Tongji Hospital is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 180Cervical Intraepithelial Neoplasia Grade 3
Exploratory Study of the Efficacy of HAL-PDT in CIN 3
This is a prospective, multicenter, biomarker-guided Phase II study evaluating the efficacy and safety of hexaminolevulinate-mediated cervical photodynamic therapy (HAL-PDT) in women with cervical intraepithelial neoplasia grade…
- Trial name
- Lumiteg-I (NCT07891338)
- Testing
- Hexaminolevulinate (HAL)
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Tongji Hospital
Cervical Intraepithelial Neoplasia Grade 2 (CIN2)
RWS of PDT for CIN 2
This is a prospective, observational, multicenter real-world study designed to evaluate the effectiveness and safety of photodynamic therapy (PDT) in women with cervical intraepithelial neoplasia grade 2 (CIN2).
- Trial name
- Lumiteg-R (NCT07885566)
- Testing
- Hexaminolevulinate (HAL)
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Solid Tumors
Lenvatinib Plus PD-1 Inhibitor for Advanced Solid Tumors With 11q13 Amplification
The goal of this clinical trial is to learn if the combination of lenvatinib and a PD-1 inhibitor (a type of immunotherapy) works to treat advanced solid tumors that have a specific genetic change called "11q13 amplification".
- Trial name
- NCT07417501
- Testing
- Lenvatinib plus PD-1 Inhibitor
- Where
- 2 sites in China
- Volunteers
- 60 people
- Sponsor
- Tongji Hospital
Frequent Episodic Tension-Type Headache
Treatment of Tension-type Headache by Zhixuan Analgesic Tablets
The goal of this clinical trial is to learn if Zhixuan Analgesic Tablet works to treat frequent episodic tension-type headache in adults aged 18-60 years. It will also learn about the safety of Zhixuan Analgesic Tablet.
- Trial name
- NCT07872943
- Testing
- Zhixuan Analgesic Tablet
- Where
- China
- Volunteers
- 212 people
- Sponsor
- Tongji Hospital
Uterine Fibroid, Uterine Sarcoma
A Prospective Validation Study of Radiomics in the Differential Diagnosis of Uterine Leiomyoma and Uterine Sarcoma
In our previous study, based on the multi-center clinical big data collected from January 2012 to January 2025, we have completed the construction of a multimodal early warning model for the malignant transformation of uterine…
- Conditions
- Uterine Fibroid, Uterine Sarcoma, AI (Artificial Intelligence), Radiomic
- Trial name
- NCT07269535
- Testing
- No intervention (observational study)
- Volunteers
- 500 people
- Sponsor
- Tongji Hospital
Muscle-Invasive Bladder Cancer (MIBC)
Response-Guided Bladder Preservation With Trastuzumab Rezetecan, Adebrelimab, and Concurrent Bladder Radiotherapy in HER2-Expressing Muscle-Invasive Bladder Cancer
This prospective, multicenter, open-label phase II study will evaluate a response-guided bladder-preservation strategy in patients with HER2-expressing muscle-invasive bladder cancer.
- Trial name
- RG-BP-MIBC (NCT07865611)
- Testing
- Trastuzumab Rezetecan, Adebrelimab, Concurrent Bladder Radiotherapy
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Tongji Hospital
Uterine Fibroid, Uterine Sarcoma
Radiomics-Based Non-Invasive MRI Differentiation of Uterine Sarcomas and Fibroids
This retrospective case-control study aims to develop and validate a diagnostic model based on multimodal big data and artificial intelligence to differentiate uterine leiomyoma from uterine sarcoma.
- Conditions
- Uterine Fibroid, Uterine Sarcoma, Diagnose Disease, AI (Artificial Intelligence)
- Trial name
- NCT07129005
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 520 people
- Sponsor
- Tongji Hospital
Anxiety, Pain
Mindfulness Intervention on Minimally Invasive Vascular Surgery
The goal of this clinical trial is to learn whether a virtual reality (VR)-based mindfulness intervention can reduce anxiety and pain in adults undergoing minimally invasive surgery for lower-extremity varicose veins under local…
- Conditions
- Anxiety, Pain, Varicose Veins of Lower Limb
- Trial name
- NCT07463638
- Testing
- VR-Based Mindfulness Intervention
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Tongji Hospital
Diabetes Mellitus, Type 2, Impaired Glucose Tolerance
Efficacy and Safety of Sanggua Tablets in the Treatment of Patients With Impaired Glucose Tolerance and Mild Type 2 Diabetes
Type 2 diabetes mellitus (T2DM) and impaired glucose tolerance (IGT) are growing public health challenges. Early intervention in mild T2DM and IGT is essential to prevent disease progression and severe complications.
- Trial name
- NCT06964620
- Testing
- Sanggua tablets
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Tongji Hospital
Parkinson s Disease
Temporal Interference Stimulation for Motor and Non-motor Symptoms in Parkinson's Disease
This study aims to evaluate the efficacy of tTIS treatment in improving motor function in patients with Parkinson's disease (PD), as well as its effects on mood, activities of daily living, sleep, cognition, and other functional…
- Trial name
- NCT07857824
- Testing
- transcranial temporal interference stimulation (tTIS)
- Volunteers
- 50 people
- Sponsor
- Tongji Hospital
Completed, with results posted
All 2Bidirectional Endoscopy
ED90 of Remimazolam Anesthesia Induction in Painless Bidirectional Endoscopy in Children
Exploring the ED90 of remimazolam in pediatric bidirectional endoscopy at different age groups.
- Trial name
- ED90 (NCT06121609)
- Testing
- Remimazolam
- Where
- China
- Volunteers
- 165 people
- Sponsor
- Tongji Hospital
Lung Cancer, Pulmonary Nodule, Solitary
Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic Segmentectomy
With the increasing acceptance of routine computed tomography (CT) screenings, early-stage lung cancer detection is becoming more frequent.
- Conditions
- Lung Cancer, Pulmonary Nodule, Solitary, Segmentectomy, Pulmonary Nodule, Multiple
- Trial name
- NCT05350137
- Testing
- 100% oxygen, Carbon dioxide
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Tongji Hospital