Research institution
University of Alberta Clinical Trials
Studies where University of Alberta is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 168Acute Heart Failure (AHF)
Routine Magnesium Testing and Supplementation in Acute Heart Failure (MAG-HF)
This study is an investigator-initiated, pragmatic, randomized controlled feasibility trial evaluating two strategies for magnesium management in adults hospitalized with acute heart failure (AHF).
- Trial name
- MAG-HF (NCT07906353)
- Testing
- No Routine Magnesium Testing or Supplementation, Routine Magnesium Testing and Supplementation
- Volunteers
- 260 people
- Sponsor
- University of Alberta
Acute Kidney Injury, Dialysis; Complications
LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)
An estimated 10-15% of critically ill patients with acute kidney failure in the intensive care unit receive acute dialysis therapy.
- Trial name
- WISDOM (NCT06446739)
- Testing
- Continuous Renal Replacement Therapy (CRRT)
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Aortic Stenosis, Severe Aortic Stenosis
Application of TAVI at Experienced Interventional Cardiac Centers Without On-site Cardiac Surgery (ATLAS Study)
The purpose of this study is to see if having the Transcatheter Aortic Valve Replacement (TAVR) procedure done in a hospital with onsite cardiac surgery available or not, makes a difference on participant outcomes.
- Trial name
- ATLAS (NCT06818006)
- Testing
- Transcatheter Aortic Valve Replacement (TAVR) with surgical oversight, Transcatheter Aortic Valve Replacement (TAVR) without surgical oversight
- Where
- 2 sites in Canada
- Volunteers
- 600 people
- Sponsor
- University of Alberta
Unilateral Vocal Cord Paralysis, Unilateral Vocal Cord Paresis
Recurrent Laryngeal Nerve Monitoring During Pediatric Aerodigestive Tract and Cardiac Surgery
This research studies whether a device used during surgery can help doctors better protect the nerve that moves a child's vocal cords. Damage to this nerve can affect speaking, swallowing, and sometimes breathing.
- Trial name
- NCT07604623
- Testing
- Intraoperative laryngeal nerve monitor
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Trained Athletes, Untrained
Trained vs. Untrained: Lower Extremity Pressure Changes
Research shows that how well oxygen moves from the lungs into the blood (called lung diffusing capacity) is linked to a person's aerobic fitness and endurance training.
- Trial name
- TULiP (NCT07897357)
- Testing
- Lower body positive and negative pressure
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Colorectal Cancer, Breast Cancer
Protein Needs Study
Severe muscle loss in patients with cancer has been associated with increased physical disability, extended hospitalization, infectious and noninfectious complications, increased risk of severe toxicity during cancer treatment…
- Trial name
- NCT04144907
- Testing
- Phenylalanine intake
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Osteoarthritis (OA) of the Knee, Physiotherapy
Pharmacist-physiotherapist Collaborative Management for Early Knee Osteoarthritis
Osteoarthritis (OA) is a slowly progressive chronic condition that is associated with aging and is characterized as joint pain. Individuals with early-stage OA usually do not seek medical attention.
- Conditions
- Osteoarthritis (OA) of the Knee, Physiotherapy, Pharmacy
- Trial name
- PACE-OA (NCT06681142)
- Testing
- Pharmacy-Physiotherapy Intervention
- Where
- Canada
- Volunteers
- 125 people
- Sponsor
- University of Alberta
Nutrition Education
Health Care Professionals Diet App Study
This study aims to evaluate MyDiet, a nutrition education app designed to improve nutrition knowledge among healthcare providers.
- Trial name
- NCT07890792
- Testing
- MyDiet App
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Meconium Aspiration Syndrome
CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)
When babies are stressed in the womb, they sometimes pass meconium in the amniotic fluid. When this happens, they may swallow the meconium-stained fluid into their lungs which may cause them to have poor oxygen levels and require…
- Trial name
- CAPUCINO (NCT06972108)
- Testing
- Caffeine citrate
- Volunteers
- 20 people
- Sponsor
- University of Alberta
High Blood Sugar, High Blood Pressure
Understanding the Health Effect of a Bioactive Peptide From Egg: A Pilot Study
Bioactive peptides derived from food proteins show potential for improving human health. One of such promising peptides is namely IRW made from egg white hydrolysate and composed of three peptides.
- Conditions
- High Blood Sugar, High Blood Pressure, Overweight and Obesity
- Trial name
- NCT06555393
- Testing
- Egg White Powder
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Completed, with results posted
All 37Newborn Infants Having Asystole or Bradycardia at Birth
Chest Compression and Sustained Inflation
Guidelines on neonatal resuscitation recommend 90 chest compressions (CC) and 30 manual inflations (3:1) per minute in newborns.
- Trial name
- NCT02083705
- Testing
- CC+SI, 3:1 CPR
- Where
- Canada
- Volunteers
- 9 people
- Sponsor
- University of Alberta
Heart Arrest, Birth Asphyxia
SI + CC Versus 3:1 C:V Ratio During Neonatal CPR
Research question In newborn infants requiring CPR, does CC superimposed by sustained inflation compared to 3:1 compression to ventilation ratio improves return of spontaneous circulation? Overall objective: CC superimposed by…
- Conditions
- Heart Arrest, Birth Asphyxia, Bradycardia
- Trial name
- SURV1VE (NCT02858583)
- Testing
- CC+SI, 3:1 C:V
- Where
- 4 sites in Austria, Canada
- Volunteers
- 27 people
- Sponsor
- University of Alberta
Stroke, Atrial Fibrillation
Post-Embolic Rhythm Detection With Implantable Versus External Monitoring
The overall aim of this trial is to determine the most cost effective approach to diagnose paroxysmal atrial fibrillation (PAF) following transient ischemic attack (TIA) and stroke.
- Conditions
- Stroke, Atrial Fibrillation, Arrhythmias, Cardiac
- Trial name
- PERDIEM (NCT02428140)
- Testing
- Medtronic Reveal LINQ, Sorin Spiderflash-t
- Where
- 3 sites in Canada
- Volunteers
- 300 people
- Sponsor
- University of Alberta
Low Back Pain
Effect of Lumbar Bracing on Spinal Function
A recent province-wide survey (Alberta, Canada) suggests that clinicians' beliefs about soft lumbar bracing for low back pain (LBP) vary substantially.
- Trial name
- NCT02251106
- Testing
- Lumbar corset (Quickdraw, Aspen Medical Products)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Epistaxis
Management of Persistent Epistaxis Using Floseal Hemostatic Matrix
Nosebleeds that persist even after adequate traditional nasal packing may require aggressive treatment strategies to stop bleeding.
- Trial name
- NCT02488135
- Testing
- Floseal Hemostatic Matrix, Traditional Nasal Packing
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- University of Alberta