Clinical trials: sponsored by University of Alberta
Acute Heart Failure (AHF)
Routine Magnesium Testing and Supplementation in Acute Heart Failure (MAG-HF)
This study is an investigator-initiated, pragmatic, randomized controlled feasibility trial evaluating two strategies for magnesium management in adults hospitalized with acute heart failure (AHF).
- Trial name
- MAG-HF (NCT07906353)
- Testing
- No Routine Magnesium Testing or Supplementation, Routine Magnesium Testing and Supplementation
- Volunteers
- 260 people
- Sponsor
- University of Alberta
Acute Kidney Injury, Dialysis; Complications
LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)
An estimated 10-15% of critically ill patients with acute kidney failure in the intensive care unit receive acute dialysis therapy.
- Trial name
- WISDOM (NCT06446739)
- Testing
- Continuous Renal Replacement Therapy (CRRT)
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- University of Alberta
Aortic Stenosis, Severe Aortic Stenosis
Application of TAVI at Experienced Interventional Cardiac Centers Without On-site Cardiac Surgery (ATLAS Study)
The purpose of this study is to see if having the Transcatheter Aortic Valve Replacement (TAVR) procedure done in a hospital with onsite cardiac surgery available or not, makes a difference on participant outcomes.
- Trial name
- ATLAS (NCT06818006)
- Testing
- Transcatheter Aortic Valve Replacement (TAVR) with surgical oversight, Transcatheter Aortic Valve Replacement (TAVR) without surgical oversight
- Where
- 2 sites in Canada
- Volunteers
- 600 people
- Sponsor
- University of Alberta
Unilateral Vocal Cord Paralysis, Unilateral Vocal Cord Paresis
Recurrent Laryngeal Nerve Monitoring During Pediatric Aerodigestive Tract and Cardiac Surgery
This research studies whether a device used during surgery can help doctors better protect the nerve that moves a child's vocal cords. Damage to this nerve can affect speaking, swallowing, and sometimes breathing.
- Trial name
- NCT07604623
- Testing
- Intraoperative laryngeal nerve monitor
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Trained Athletes, Untrained
Trained vs. Untrained: Lower Extremity Pressure Changes
Research shows that how well oxygen moves from the lungs into the blood (called lung diffusing capacity) is linked to a person's aerobic fitness and endurance training.
- Trial name
- TULiP (NCT07897357)
- Testing
- Lower body positive and negative pressure
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Colorectal Cancer, Breast Cancer
Protein Needs Study
Severe muscle loss in patients with cancer has been associated with increased physical disability, extended hospitalization, infectious and noninfectious complications, increased risk of severe toxicity during cancer treatment…
- Trial name
- NCT04144907
- Testing
- Phenylalanine intake
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Osteoarthritis (OA) of the Knee, Physiotherapy
Pharmacist-physiotherapist Collaborative Management for Early Knee Osteoarthritis
Osteoarthritis (OA) is a slowly progressive chronic condition that is associated with aging and is characterized as joint pain. Individuals with early-stage OA usually do not seek medical attention.
- Conditions
- Osteoarthritis (OA) of the Knee, Physiotherapy, Pharmacy
- Trial name
- PACE-OA (NCT06681142)
- Testing
- Pharmacy-Physiotherapy Intervention
- Where
- Canada
- Volunteers
- 125 people
- Sponsor
- University of Alberta
Low Back Pain
Alberta Back Care Pathway (ABCp)
Every year, the pain, disability, addiction, and expense associated with LBP increase in Alberta. This escalation is largely because most people with LBP seek care from family physicians who are unable to provide effective…
- Trial name
- ABCp (NCT05452876)
- Testing
- ABCp, Usual Care
- Where
- Canada
- Volunteers
- 713 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Nutrition Education
Health Care Professionals Diet App Study
This study aims to evaluate MyDiet, a nutrition education app designed to improve nutrition knowledge among healthcare providers.
- Trial name
- NCT07890792
- Testing
- MyDiet App
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Meconium Aspiration Syndrome
CAffeine Use in Prolonged Oxygen Use in meConium aspIration Syndrome in Neonatal Outcomes (CAPUCINO)
When babies are stressed in the womb, they sometimes pass meconium in the amniotic fluid. When this happens, they may swallow the meconium-stained fluid into their lungs which may cause them to have poor oxygen levels and require…
- Trial name
- CAPUCINO (NCT06972108)
- Testing
- Caffeine citrate
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Health Literacy, Anticoagulation
Electronic KIDCLOT Interactive Thrombosis/Thrombophilia Education; A Quality Assurance Initiative
Effective patient education improves health literacy and engagement thus improving long-term health outcomes. Health literacy is imperative to make informed health decisions and relies on the ability to obtain, process and…
- Trial name
- eKITE (NCT03910933)
- Testing
- elearning patient information
- Where
- 6 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- University of Alberta
High Blood Sugar, High Blood Pressure
Understanding the Health Effect of a Bioactive Peptide From Egg: A Pilot Study
Bioactive peptides derived from food proteins show potential for improving human health. One of such promising peptides is namely IRW made from egg white hydrolysate and composed of three peptides.
- Conditions
- High Blood Sugar, High Blood Pressure, Overweight and Obesity
- Trial name
- NCT06555393
- Testing
- Egg White Powder
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alberta
PreDiabetes, Diabetes Mellitus, Type 2
Metabolic and Inflammatory Outcomes of the Ketogenic Diet Comparing Saturated and Unsaturated Fat Sources
The goal of this clinical trial is to compare a healthy KETO diet supplemented with canola oil (KETO-Can) compared to a traditional KETO diet high in saturated fat (KETO-Sat) and low-fat diet (LFD) in adults at high risk of or…
- Conditions
- PreDiabetes, Diabetes Mellitus, Type 2, Overweight and Obesity
- Trial name
- KETO-IM (NCT05681468)
- Testing
- Keto-SAT, Keto-CAN, LFD
- Where
- Canada
- Volunteers
- 164 people
- Sponsor
- University of Alberta
Psychotic Disorders, Family Members
Supporting Patients by Family Education in Psychotic Illness: A Prospective Cohort Study
Background: A lack of education, resources, and support for family carers of young adults with psychotic illnesses leaves them ill-equipped to support their loved one.
- Conditions
- Psychotic Disorders, Family Members, Anosognosia, Paranoia
- Trial name
- NCT05500001
- Testing
- Supporting Patients by Family Education in Psychotic Illness Group
- Where
- 4 sites in Canada
- Volunteers
- 113 people
- Sponsor
- University of Alberta
Chronic Kidney Disease
Effects of Minimally vs. Ultra-Processed Diets on Potassium (K) Handling in CKD
What is this study about? This clinical trial is designed to learn how potassium from different types of food affects blood potassium levels and overall health in people with chronic kidney disease (CKD, stages 3B-5).
- Trial name
- K-HANDLE CKD (NCT06920914)
- Testing
- Low-potassium, ultra-processed diet, Low-potassium, minimally processed diet, Normal potassium-rich, minimally processed diet
- Volunteers
- 48 people
- Sponsor
- University of Alberta
Stroke
Behavioral Intervention and Guided Stepping Training Early Post-Stroke
Low daily steps and prolonged sedentary behavior are associated with reduced functional outcomes and quality of life in patients with stroke.
- Trial name
- BIG STEPS (NCT07702643)
- Testing
- Behavior and guided stepping training intervention (BIG STEPS), DELAYED Behavior and guided stepping training intervention
- Where
- 6 sites in Canada
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Fibrotic Interstitial Lung Disease
Ambulatory Oxygen Therapy for Individuals With Mild-to-moderate Interstitial Lung Disease
The investigators plan to conduct a study to find out if giving portable oxygen therapy (during physical activity) to patients with interstitial lung disease will improve quality of life, exercise tolerance, shortness of breath…
- Trial name
- NCT06053164
- Testing
- Exertional Oxygen, Education and Support
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Alberta
Depression, Anxiety
Integrating Inuit Knowledge Principles in Multi-Level Mental Health Clinical Trials
This study is looking at how eating more country foods affects mental health among Inuit men and women in Arviat, NU. The goal is to evaluate if eating more of these foods helps people feel less depressed or anxious, and whether…
- Trial name
- NCT07014852
- Testing
- Traditional Country Foods, Cultural Workshops
- Where
- 2 sites in Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Neuroendocrine Tumors
Lesion-to-lesion Comparison of 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG PET/CT in the Evaluation of Metastatic Neuroendocrine Tumors
This study is a single centre non-randomized non-blinded phase II prospective cohort study including 50 participants. The objective of this study is to directly compare 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG activity in patients…
- Trial name
- NCT05255159
- Testing
- 18F-DOPA with furosemide
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Alberta
Chronic Diseases in Adolescence
Wichitasowin: Indigenous Patient Navigator for Young Adults Study
The objective of this pathway is to establish and evaluate a novel Indigenous-led patient navigator (IPN) program for Indigenous adolescents living with chronic health conditions in Maskwacis, Alberta.
- Trial name
- Wichitasowin (NCT06443190)
- Testing
- Indigenous Patient Navigator Support
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta