Research institution
University of Illinois Chicago Clinical Trials
Studies where University of Illinois Chicago is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 128Iron Deficiency (ID), Pregnancy
Probiotic Supplementation in Optimizing Iron and Hematological Status Among Pregnant Females
Maternal iron deficiency (ID) and iron deficiency anemia (IDA) is associated with maternal and infant mortality, spontaneous preterm birth, maternal postpartum hemorrhage, and neurocognitive defects in the neonate.
- Trial name
- ProMoms (NCT07076849)
- Testing
- Lactiplantibacillus plantarum 299v
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Persistent Corneal Epithelial Defect, Corneal Epithelial Disorders
Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease
In this phase II randomized double-masked clinical trials, subjects with non-resolving corneal epithelial disease/defect (i.e., refractory to standard treatments for at least two weeks) will receive 8 weeks treatment of topical…
- Trial name
- NCT06919081
- Testing
- Allogeneic Bone-Marrow Derived Mesenchymal Stromal Cells Secretome, Vehicle Control
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Illinois Chicago
Sleep, Physical Activity
On Track for Wellness (OTW) Stepped Wedge Cluster Randomized Trial
This study will evaluate a program called On Track for Wellness (OTW) which is being adopted by the Illinois Department of Human Services' Division of Behavioral Health \& Recovery (DBHR) for use in all state-funded early…
- Conditions
- Sleep, Physical Activity, First Episode Psychosis
- Trial name
- OTW (NCT07387705)
- Testing
- On Track for Wellness
- Where
- United States
- Volunteers
- 365 people
- Sponsor
- University of Illinois Chicago
Plasmablastic Lymphoma, HIV
HEME-25 Open-Label Feasibility Study of Elranatamab Utilized as Consolidation in Newly Diagnosed Plasmablastic Lymphoma With or Without HIV
This is a single-arm feasibility trial in which patients with histologically confirmed plasmablastic lymphoma (PBL) with or without HIV, who have achieved a Complete Response or Partial Response after definitive frontline…
- Conditions
- Plasmablastic Lymphoma, HIV, Consolidation
- Trial name
- HEME-25 (NCT07647432)
- Testing
- Elranatamab (Elra)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Illinois Chicago
Cannabis Use, Substance Use Disorder (SUD)
Research Investigating Drug Effects-2 (RiDE-2)
The purpose of this study is to better understand how people's mood, behavior, and brains respond to different recreational drugs.
- Conditions
- Cannabis Use, Substance Use Disorder (SUD), Healthy
- Trial name
- RiDE-2 (NCT06758596)
- Testing
- THC
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
At Risk for AD-dementia, With Subjective Cognitive Decline, At Risk for Cognitive Decline
High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults
The goal of this clinical trial is to learn whether a 12-week high-velocity resistance training program can improve brain blood flow and thinking skills in adults ages 60 to 79 who are at higher risk for Alzheimer's disease and…
- Trial name
- NCT07444554
- Testing
- High-Velocity Resistance Training
- Volunteers
- 60 people
- Sponsor
- University of Illinois Chicago
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois Chicago
Awake Fiberoptic Intubation, Difficult Airway
Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation
The purpose of this study is to examine the effects of different sedation drugs used for the awake fiberoptic intubation procedure.
- Trial name
- NCT05736198
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Illinois Chicago
Lower Limb Amputation Above Knee, Below Knee Amputation
Determining the Effects of Ischemic Conditioning and Neuromuscular Electrical Stimulation on Overall Function After Lower Limb Amputation
The goal of this clinical trial is to learn if ischemic conditioning and neuromuscular electrical stimulation improves muscle strength and walking behavior in those with limb loss.
- Trial name
- NCT07664995
- Testing
- Blood pressure cuff, Neuromuscular Electrical Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Illinois Chicago
Chronic Kidney Disease, Diabetes
CKD Awareness, Referrals, Education, and Support Intervention for Early-Stage CKD
The goal of this pilot clinical trial is to learn if an intervention delivering education, motivational support, and social support can prevent worsening kidney disease in adults with diabetes and early-stage kidney disease.
- Trial name
- CARES (NCT07210710)
- Testing
- CKD Awareness, Referrals, Education, and Support (CARES), Attention control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Completed, with results posted
All 107Resilience, Psychological, Advance Care Planning
Facilitating Advance Care Planning Discussions for People With Advanced Cancer
The aims of this study are to (1) identify the advance care planning deliberation process among 20 dyads of patients with advanced cancer and family caregivers and (2) conduct usability testing among 9 dyads to refine the content…
- Trial name
- NCT06061965
- Testing
- Web-based resilience-building intervention
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Illinois Chicago
Behavioral Health
Feasibility Testing a Meditation App for Youth in the Legal System
This feasibility clinical trial aims to assess the feasibility of implementing a 1-month app-based meditation program with youth in the juvenile legal system. The primary questions it is designed to answer are: 1.
- Trial name
- NCT05146167
- Testing
- Bodhi AIM (intervention group), HIB (control group)
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Mindfulness, Colon Cancer
Targeting Chronic Stress for Reducing Risk Factors for Colorectal Cancer
Many neighborhoods in Chicago experience daily exposure to stressors including economic inopportunity and violent crime in public spaces.
- Conditions
- Mindfulness, Colon Cancer, Females
- Trial name
- MindCRC (NCT06323421)
- Testing
- Mindfulness
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Obesity, Hypertension
HealthMatters@24/7 eLearning for People Supporting Adults With Intellectual and Developmental Disabilities
The barriers faced by people with intellectual and developmental disabilities (IDD) begin in their mid to late 20s and often mirror the experiences of older adults (50+) living in the U.S.
- Conditions
- Obesity, Hypertension, Hypercholesterolemia, Hyperglycemia
- Trial name
- HM@24/7 (NCT03206164)
- Testing
- Asynchronous, eLearning Intervention
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Heart Failure
Patient-centered Mobile Health Intervention to Improve Self-care in Patients With Chronic Heart Failure
Approximately 6.5 million people have heart failure (HF) in the United States, and 960,000 new cases are reported each year. HF is one of the most common hospital diagnosis among older adults.
- Trial name
- iCardia4HF (NCT03642275)
- Testing
- iCardia4HF
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Illinois Chicago