Research institution
Zealand University Hospital Clinical Trials
Studies where Zealand University Hospital is the lead sponsor: what is enrolling now, by phase, condition and country.
In numbers
Open to volunteers: recruiting, not yet recruiting or enrolling by invitation. Active adds studies under way that have stopped recruiting.
Open to volunteers
All 44Alcohol Use Disorder
The Connect Trial: Connecting Hospital Patients to Alcohol Care
The main objective of this pilot study is to assess feasibility of conducting a definitive RCT with concealed allocation, blinded outcome assessment and a 1:1 parallel group design of A) an invitation to meet an AUD therapist for…
- Trial name
- NCT07482150
- Testing
- AUD treatment sessions with an outreach alcohol therapist at the hospital, Guidance and leaflet on AUD treatment facilities outside the hospital
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Zealand University Hospital
Hip Arthroplasty, Knee Arthroplasty
Anaesthesia for Hip and Knee Arthroplasty (SPIGA)
Beneficial and harmful effects of spinal versus general anaesthesia in patients undergoing hip and knee arthroplasty.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia, General Anesthesia
- Trial name
- SPIGA (NCT07834242)
- Testing
- Spinal anaesthesia, General anaesthesia
- Volunteers
- 3,000 people
- Sponsor
- Zealand University Hospital
Large B-Cell Lymphoma (LBCL), Multiple Myeloma (MM)
Restrictive Versus Standard Antibiotic Treatment During CAR-T Therapy
The purpose of the CARMic study is to investigate whether a restrictive, microbiome-sparing antibiotic strategy can better preserve the gut microbiota in patients undergoing chimeric antigen receptor T-cell (CAR-T) therapy…
- Conditions
- Large B-Cell Lymphoma (LBCL), Multiple Myeloma (MM), Gut Microbiota
- Trial name
- CARMic (NCT07842198)
- Testing
- ceftazidime, ciprofloxacin, Standard-of-Care Antibiotic Strategy
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Zealand University Hospital
Hearing Aid, Telehealth
Effectiveness and Acceptability of Remote Fine-Tuning of Hearing Aids in Danish Adults
The aim of this clinical trial is to evaluate the effectiveness and user satisfaction of remote fine-tuning of hearing aids compared to traditional face-to-face adjustments.
- Conditions
- Hearing Aid, Telehealth, Hearing Aid Fitting, Effectiveness
- Trial name
- EARFit (NCT06992778)
- Testing
- Remote fine-tuning of hearing aids, Face-to-face fine-tuning of hearing aids
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Zealand University Hospital
Colo-rectal Cancer
The AIDPRO-CRC Trial
The AIDPRO-CRC trial aims to improve outcomes for patients undergoing surgery for colorectal cancer by using artificial intelligence (AI) to assist surgeons in risk assessment.
- Trial name
- AIDPRO-CRC (NCT06645015)
- Testing
- AI augmented risk-stratification, Expert-based Risk-stratification
- Where
- 8 sites in Denmark
- Volunteers
- 1,200 people
- Sponsor
- Zealand University Hospital
Hemodialysis
Prophylactic Antibiotic Treatment in Hemodialysis
The purpose of this study is to assess the efficacy of prophylactic antibiotic treatment on blood stream infections and severe culture negative infections, in patients on newly started hemodialysis(HD), with a central venous…
- Trial name
- PANTHEM (NCT05248620)
- Where
- 7 sites in Denmark
- Volunteers
- 800 people
- Sponsor
- Zealand University Hospital
Hematologic Cancer, Acute Myeloid Leukaemia (AML)
Home-based Intravenous Cytarabine Treatment for Acute Myeloid Leukemia: a National Danish Study of Feasibility, Costs, and Implementation
The goal of this observational multicenter feasibility and implementation study is to evaluate home-based treatment with intravenous Cytarabine for patients with acute myeloid leukemia in Denmark.
- Conditions
- Hematologic Cancer, Acute Myeloid Leukaemia (AML), Hospital At Home, Home-based Chemotherapy
- Trial name
- HOME-CALM (NCT07802015)
- Volunteers
- 80 people
- Sponsor
- Zealand University Hospital
Dementia (Diagnosis), Alzheimer Dementia (AD)
Speech-Based Artificial Intelligence for Detection of Dementia in Danish Patients (DetectAI)
The goal of this observational study is to learn if an artificial intelligence (AI)-based speech analysis tool can identify which patients with memory problems need specialist evaluation at a memory clinic.
- Conditions
- Dementia (Diagnosis), Alzheimer Dementia (AD), Vascular Dementia (VaD), Lewy Body Dementia (LBD)
- Trial name
- DetectAI (NCT07200739)
- Testing
- Mini-mental State Examination, Addenbrooke's Cognitive Examination, Speech Task - Picture Description
- Where
- Denmark
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Upper Gastrointestinal Disorder
Endoscopists' Perspectives on the Use of Single-Use Gastroscopes in Elective and Subacute Patients in the Endoscopy Unit
The aim of this clinical trial is to investigate whether single-use gastroscopes perform comparably to reusable gastroscopes when used in an endoscopy unit during a period of reduced endoscope reprocessing capacity.
- Trial name
- NCT07727226
- Testing
- Ambu aScope Gastro, Reusable diagnostic gastroscopes (Olympus)
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Zealand University Hospital
Upper Gastrointestinal Disorder
Performance Characteristics and Technical Outcomes of Single-use Gastroscopes Used Bedside Versus Reusable Gastroscopes Used in the Endoscopy Unit Evaluated in Subacute Patients
The aim of this study is to investigate whether single-use gastroscopes used bedside can reduce the time from indication to procedure compared with re-usable gastroscopes used at the endoscopy unit in patients referred to a…
- Trial name
- NCT06771102
- Testing
- Ambu aScope Gastro, Diagnostic gastroscopes, Olympus
- Where
- Denmark
- Volunteers
- 180 people
- Sponsor
- Zealand University Hospital
Completed, with results posted
All 3Feasibility Study
Stool Sampling in the Acute Isolated Patient , Efficient Acquiring With a Novel Device
stool sample device tested on patients admitted to oncological dept. with diarrhea, in order to shorten time in isolation and time to relevant treatment.
- Trial name
- NCT06495775
- Testing
- quickfact
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Zealand University Hospital
Dementia, Dementia With Lewy Bodies
Monitoring Anti-Dementia Drugs by Serum Levels
The main objective of the MONANTI study is twofold: Firstly, to determine the serum concentration (SC) the anti-dementia drugs donepezil and memantine in a broadly defined clinical population of patients suffering from dementia…
- Conditions
- Dementia, Dementia With Lewy Bodies, Dementia in Parkinsons Disease, Dementia Alzheimers
- Trial name
- MONANTI (NCT04117178)
- Testing
- Donepezil, Memantine, Measurement of serum level of anti-dementia drug
- Where
- Denmark
- Volunteers
- 132 people
- Sponsor
- Zealand University Hospital
Bile Acid Malabsorption, Cholelithiasis
Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy
Investigate serial plasma samples of fibroblast growth factor 19 (FGF19) after oral stimulation with chenodeoxycholic acid in the same subjects before and after elective cholecystectomy
- Trial name
- BACH (NCT03168555)
- Testing
- chenodeoxycholic acid
- Where
- Denmark
- Volunteers
- 23 people
- Sponsor
- Zealand University Hospital