Ureteral ObstructionNCT00199472
Comparison of Dynamic Contrast Enhanced CT and Diuretic Renogram in The Evaluation of UPJO
An observational study of Ureteral Obstruction, run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's at 1 site in Canada.
Trial summary
Renal blood flow is inversely related to obstruction. We propose that this imaging will be as effective as the diuretic renogram in the functional diagnosis of obstruction. Furthermore, dynamic contrast CT scanning may also add anatomic information necessary for the surgical treatment. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Ureteral Obstruction
- What is being tested?
- Dynamic Contrast Enhanced CT & Diuretic Renogram
- Type of treatment
- Surgery or procedure
- How many people
- 0 participants
- Where
- 1 siteCanada
- Study dates
- Start not givento Jun 2001
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- 18 years of age or older;
- Subjects suspected to have UPJO.
Who cannot join
- Pregnancy;
- Renal failure (Creatinine >150);
- Allergy to contrast material;
- Ureteral stent;
- Nephrostomy tube;
- Renal pelvis calculi.
Trial locations and contacts
1 site in 1 country.
Canada1 site
Urology Clinic, St. Joseph's Hospital, St. Joseph's Health Care London
London, Ontario, N6A 4V2
About this study
Official title: Comparison of Dynamic Contrast Enhanced CT and Diuretic Renogram in The Evaluation of Ureteropelvic Junction Obstruction
Renal blood flow is inversely related to obstruction. We propose that this imaging will be as effective as the diuretic renogram in the functional diagnosis of obstruction. Furthermore, dynamic contrast CT scanning may also add anatomic information necessary for the surgical treatment.
- Conditions
- Ureteral Obstruction
- Being tested
- Dynamic Contrast Enhanced CT & Diuretic Renogram
- Medical subject headings
- Ureteral Obstruction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dynamic Contrast Enhanced CT & Diuretic RenogramProcedure or surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Sep 2005 (estimated)
- Study completionJun 2001
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ureteral ObstructionStudies of the same condition, open and under way.
- More trials run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Time perspective
- Prospective
- Enrolment
- 0 participants (actual)
Sponsor and investigators
- Lead sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
- Sponsor type
- University, hospital or other
- Collaborators
- St. Joseph's Health Care London, General Electric
- Responsible party
- Sponsor
- Investigators
- John D Denstedt, MD, FRCSC, Principal investigator, Urology, St. Joseph's Hospital, University of Western Ontario
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00199472
- Sponsor's protocol ID
- 07378
- Status last verified
- Aug 2017
- First submitted
- 13 Sep 2005
- Last updated
- 25 Aug 2017
- Results posted
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Aug 2017. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Dynamic Contrast Enhanced CT and Diuretic Renogram in The Evaluation of Ureteropelvic Junction Obstruction
- ClinicalTrials.gov ID
- NCT00199472
- Acronym / sponsor ID
- 07378
- Conditions
- Ureteral Obstruction
- Study type
- Observational
- Recruitment status
- Withdrawn
- Enrolment
- 0 participants (actual)
- Lead sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sUniversity, hospital or other
- Collaborators
- St. Joseph's Health Care London, General Electric
- Study completion
- Jun 2001 (actual)
- First posted
- 20 Sep 2005 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Renal blood flow is inversely related to obstruction. We propose that this imaging will be as effective as the diuretic renogram in the functional diagnosis of obstruction. Furthermore, dynamic contrast CT scanning may also add anatomic information necessary for the surgical treatment.
Study design
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- 18 years of age or older;
- Subjects suspected to have UPJO.
Key exclusion criteria (6 listed)
- Pregnancy;
- Renal failure (Creatinine >150);
- Allergy to contrast material;
- Ureteral stent;
- Nephrostomy tube;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dynamic Contrast Enhanced CT & Diuretic Renogram | Procedure or surgery | – |
Primary outcome
Not reported in the source record.
Results and safety
The study was withdrawn before enrolling participants, so there are no results.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Aug 2017.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
John D Denstedt, MD, FRCSC principal investigator
Urology, St. Joseph's Hospital, University of Western Ontario
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Ureteral Obstruction, run by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: withdrawn, as of the sponsor's last update on 25 Aug 2017. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was withdrawn before enrolling participants, so there are no results.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Aug 2017.