ObesityNCT00327821
The Effectiveness of Commercial Weight Loss Programmes
A study of Obesity, run by University of Surrey at 1 site in United Kingdom.
Trial summary
The objective is to compare the effectiveness of 4 different commercial weight-loss diets available to adults in the UK. This is achieved with a 6 month multi-centre randomised unblinded controlled trial of Dr Atkins' New Diet Revolution, The slimFast Plan, The weight Watchers Pure Points Programme, Rosemary Conley's… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Obesity
- Type of treatment
- Lifestyle or therapy programme
- How many people
- 300 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- Jul 2002to Mar 2003
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Body mass index (BMI) > 27 and < 40 kg/m2.
Who cannot join
- History of coronary heart disease
- Type 1 or Type 2 diabetes
- Renal, liver or respiratory failure
- Gout
- Taking lipid lowering or anti-hypertensive drugs
- History of obesity with known cause (i.e. Cushings disease, hypothyroidism)
Show all 15Show fewer
- Previous gastric or weight loss surgery
- Taking any weight loss drug (including Orlistat or Sibutramine)
- Clinical depression
- Eating disorders
- Drug or alcohol abuse
- Any malabsorptive state (including lactose intolerance)
- Being treated for a malignancy
- Being pregnant
- Breastfeeding
Trial locations and contacts
1 site in 1 country.
About this study
Official title: A Randomised Control Trial of Commercial Weight Loss Programme in a Community Based Sample of Obese Adults.
The objective is to compare the effectiveness of 4 different commercial weight-loss diets available to adults in the UK.
This is achieved with a 6 month multi-centre randomised unblinded controlled trial of
- Dr Atkins' New Diet Revolution,
- The slimFast Plan,
- The weight Watchers Pure Points Programme,
- Rosemary Conley's "Eat Yourself Slim" Diet \& Fitness Plan.
- No diet (control)
Subjects are a community based sample of 300 (60 per group) otherwise healthy overweight and obese adults.
Main outcome measures are weight and body fat change over 6 months.
- Conditions
- Obesity
- Being tested
- calorie controlled diet
- Medical subject headings
- Obesity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
calorie controlled dietBehavioural
What is being measured
The primary outcome is the main question the study is designed to answer.
Weight loss
Fat loss
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 May 2006 (estimated)
- Study startJul 2002
- Study completionMar 2003
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for ObesityStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 300 participants
Sponsor and investigators
- Lead sponsor
- University of Surrey
- Sponsor type
- University, hospital or other
- Collaborators
- British Broadcasting Corporation
- Investigators
- D J Millward, PhD, Principal investigator, University of SurreyH A Truby, PhD SRD, Study director, University of Surrey
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00327821
- Sponsor's protocol ID
- 107189 BBC
- Status last verified
- May 2003
- First submitted
- 17 May 2006
- Last updated
- 21 Jul 2006
- Results posted
- No
Publications
Truby H, Baic S, deLooy A, Fox KR, Livingstone MB, Logan CM, Macdonald IA, Morgan LM, Taylor MA, Millward DJ. Randomised controlled trial of four commercial weight loss programmes in the UK: initial findings from the BBC "diet trials". BMJ. 2006 Jun 3;332(7553):1309-14. doi: 10.1136/bmj.38833.411204.80. Epub 2006 May 23.
PubMed 16720619Truby H, Hiscutt R, Herriot AM, Stanley M, Delooy A, Fox KR, Baic S, Robson PJ, Macdonald I, Taylor MA, Ware R, Logan C, Livingstone M. Commercial weight loss diets meet nutrient requirements in free living adults over 8 weeks: a randomised controlled weight loss trial. Nutr J. 2008 Sep 2;7:25. doi: 10.1186/1475-2891-7-25.
PubMed 18764946
Study at a glance
From the registry record, last updated by the sponsor on 21 Jul 2006. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Randomised Control Trial of Commercial Weight Loss Programme in a Community Based Sample of Obese Adults.
- ClinicalTrials.gov ID
- NCT00327821
- Acronym / sponsor ID
- 107189 BBC
- Conditions
- Obesity
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 300 participants
- Lead sponsor
- University of SurreyUniversity, hospital or other
- Collaborators
- British Broadcasting Corporation
- Study start
- Jul 2002
- Study completion
- Mar 2003
- First posted
- 19 May 2006 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The objective is to compare the effectiveness of 4 different commercial weight-loss diets available to adults in the UK.
This is achieved with a 6 month multi-centre randomised unblinded controlled trial of
- Dr Atkins' New Diet Revolution,
- The slimFast Plan,
- The weight Watchers Pure Points Programme,
- Rosemary Conley's "Eat Yourself Slim" Diet \& Fitness Plan.
- No diet (control)
Subjects are a community based sample of 300 (60 per group) otherwise healthy overweight and obese adults.
Main outcome measures are weight and body fat change over 6 months.
Study design
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Body mass index (BMI) > 27 and < 40 kg/m2.
Key exclusion criteria (15 listed)
- History of coronary heart disease
- Type 1 or Type 2 diabetes
- Renal, liver or respiratory failure
- Gout
- Taking lipid lowering or anti-hypertensive drugs
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| calorie controlled diet | Behavioural | – |
Primary outcome
Weight loss
Fat loss
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 21 Jul 2006.
- Results publication: PubMed 16720619Truby H, Baic S, deLooy A, Fox KR, Livingstone MB, Logan CM, Macdonald IA, Morgan LM, Taylor MA, Millward DJ. Randomised controlled trial of four commercial weight loss programmes in the UK: initial findings from the BBC "diet trials". BMJ. 2006 Jun 3;332(7553):1309-14. doi: 10.1136/bmj.38833.411204.80. Epub 2006 May 23.
- Derived from this study: PubMed 18764946Truby H, Hiscutt R, Herriot AM, Stanley M, Delooy A, Fox KR, Baic S, Robson PJ, Macdonald I, Taylor MA, Ware R, Logan C, Livingstone M. Commercial weight loss diets meet nutrient requirements in free living adults over 8 weeks: a randomised controlled weight loss trial. Nutr J. 2008 Sep 2;7:25. doi: 10.1186/1475-2891-7-25.
Related trials for Obesity
Recruiting
Preserving Muscle Mass During Incretin-Induced Weight Loss
Obesity (BMI > 35)
Not yet recruitingObservational study
A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity
Obesity
Not yet recruitingObservational study
Assessing the Impact of Perceptions of Unpredictability on Objective Measures of Food Consumption and Metabolism
Healthy Volunteer, Obestity
Not yet recruitingPhase 2
Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity
Insulin Resistance, Obesity
Recruiting
Synchronous vs Asynchronous Remotely Delivered Lifestyle Interventions
Obesity
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
D J Millward, PhD principal investigator
University of Surrey
H A Truby, PhD SRD study director
University of Surrey
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study of Obesity, run by University of Surrey at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 15 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 21 Jul 2006. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Weight loss. The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00327821, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 21 Jul 2006.