Multiple SclerosisNCT00510523
Whole Body Vibration Therapy in Participants With MS Related Balance Deficits
A study testing Whole Body Vibration machine in people with Multiple Sclerosis, run by Logan College of Chiropractic at 2 sites in United States.
Trial summary
The purpose of this investigation is to determine the effect of Whole Body Vibration Therapy (WBV) on balance in participants with multiple sclerosis (MS) related balance deficits as measured by the NeuroCom Balance Master, the Sapphire IIME EMG Device and the Kurtzke Expanded Disability Status Scale (EDSS) and the… Read more about this study
- Who is it for?
- Ages 25 to 65 years
- Conditions the study is for
- Multiple Sclerosis
- What is being tested?
- Whole Body Vibration machine
- Type of treatment
- Medical device
- How many people
- 80 participants
- Where
- 2 sitesUnited States
- Study dates
- Oct 2006to Nov 2007
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Logan student, staff, or faculty or general public with a minimal of 2 year history of diagnosed Multiple Sclerosis (MS)
Who cannot join
- Visual or vestibular condition that would affect balance
- Non-Ms related systemic illness that would have an adverse effect on balance
- Local infection, acute inflammation, injury, tumors or other malignancy, recent wounds, diabetes
- Any unstable joints of the lower extremity, recent hip and knee joints or fitted hip or knee pins, bolts and/or plates
- Acute thrombosis
- Severe migraine, epilepsy
Show all 12Show fewer
- Serious cardiovascular disease, wearing a pacemaker
- Any Spinal manipulation within 48 hours
- Acute disc herniation, discopathy or spondylolysis
- Prescription or herbal muscle stimulants, relaxants, etc. that could affect balance
- Any implanted device or prosthesis or intrauterine IUD type of device
- Pregnancy
Trial locations and contacts
2 sites in 1 country.
United States2 sites
Logan University, College of Chiropractic
Chesterfield, Missouri, 63017
Logan University, College of Chirpractic
Chesterfield, Missouri, 63017
About this study
The purpose of this investigation is to determine the effect of Whole Body Vibration Therapy (WBV) on balance in participants with multiple sclerosis (MS) related balance deficits as measured by the NeuroCom Balance Master, the Sapphire IIME EMG Device and the Kurtzke Expanded Disability Status Scale (EDSS) and the Berg Balance Score.
- Conditions
- Multiple Sclerosis
- Being tested
- Whole Body Vibration machine
- Keywords
- MS, Balance, Multiple Sclerosis
- Medical subject headings
- Multiple Sclerosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Whole Body Vibration machineDevice
What is being measured
The primary outcome is the main question the study is designed to answer.
NeuroCom Balance Master
SF-EMG Nerve conduction velocity test
Berg balance score
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Aug 2007 (estimated)
- Study startOct 2006
- Study completionNov 2007
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Multiple SclerosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Logan College of Chiropractic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dennis Enix, DC, MBA, Logan College of Chiropractic
- Investigators
- Dennis Enix, DC, MBA, Principal investigator, Logan College of ChiropracticDennis Enix, DC, MBA, Principal investigator, Logan University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00510523
- Sponsor's protocol ID
- RD0731060030
- Status last verified
- May 2013
- First submitted
- 31 Jul 2007
- Last updated
- 3 May 2013
- Results posted
- No
Publications
Romberg A, Virtanen A, Ruutiainen J, Aunola S, Karppi SL, Vaara M, Surakka J, Pohjolainen T, Seppanen A. Effects of a 6-month exercise program on patients with multiple sclerosis: a randomized study. Neurology. 2004 Dec 14;63(11):2034-8. doi: 10.1212/01.wnl.0000145761.38400.65.
PubMed 15596746Griffin JW. Use of proprioceptive stimuli in therapeutic exercise. Phys Ther. 1974 Oct;54(10):1072-9. doi: 10.1093/ptj/54.10.1072. No abstract available.
PubMed 4422763
Study at a glance
From the registry record, last updated by the sponsor on 3 May 2013. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Whole Body Vibration Therapy in Participants With MS Related Balance Deficits
- ClinicalTrials.gov ID
- NCT00510523
- Acronym / sponsor ID
- RD0731060030
- Conditions
- Multiple Sclerosis
- Keywords
- MS, Balance, Multiple Sclerosis
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Logan College of ChiropracticUniversity, hospital or other
- Study start
- Oct 2006
- Study completion
- Nov 2007
- First posted
- 2 Aug 2007 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this investigation is to determine the effect of Whole Body Vibration Therapy (WBV) on balance in participants with multiple sclerosis (MS) related balance deficits as measured by the NeuroCom Balance Master, the Sapphire IIME EMG Device and the Kurtzke Expanded Disability Status Scale (EDSS) and the Berg Balance Score.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
Who may qualify
- Ages
- 25 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Logan student, staff, or faculty or general public with a minimal of 2 year history of diagnosed Multiple Sclerosis (MS)
Key exclusion criteria (12 listed)
- Visual or vestibular condition that would affect balance
- Non-Ms related systemic illness that would have an adverse effect on balance
- Local infection, acute inflammation, injury, tumors or other malignancy, recent wounds, diabetes
- Any unstable joints of the lower extremity, recent hip and knee joints or fitted hip or knee pins, bolts and/or plates
- Acute thrombosis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Whole Body Vibration machine | Device | – |
Primary outcome
NeuroCom Balance Master
SF-EMG Nerve conduction velocity test
Berg balance score
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 May 2013.
- Background: PubMed 15596746Romberg A, Virtanen A, Ruutiainen J, Aunola S, Karppi SL, Vaara M, Surakka J, Pohjolainen T, Seppanen A. Effects of a 6-month exercise program on patients with multiple sclerosis: a randomized study. Neurology. 2004 Dec 14;63(11):2034-8. doi: 10.1212/01.wnl.0000145761.38400.65.
- Background: PubMed 4422763Griffin JW. Use of proprioceptive stimuli in therapeutic exercise. Phys Ther. 1974 Oct;54(10):1072-9. doi: 10.1093/ptj/54.10.1072. No abstract available.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Dennis Enix, DC, MBA principal investigator
Logan College of Chiropractic
Dennis Enix, DC, MBA principal investigator
Logan University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Whole Body Vibration machine in people with Multiple Sclerosis, run by Logan College of Chiropractic at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 May 2013. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NeuroCom Balance Master. The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00510523, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 May 2013; AzTrials last refreshed its copy on 7 Nov 2026.