TroponinNCT00560040
Myocardial Injury is Not Related to Training Levels Among Recreational Participants in the Silicon Valley Marathon
An observational study of Troponin and Natriuretic Peptide, Brain, run by Stanford University.
Trial summary
To determine if pre-race training effects heart damage induced by marathon running. Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Troponin, Natriuretic Peptide, Brain, Exercise
- How many people
- 53 participants
- Where
- No sites listed yet
- Study dates
- Jan 2006to Oct 2006
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Any healthy male or female aged 18-65 planning to run the 2006 Silicon Valley Marathon.
Who cannot join
- Hypertension
- Hyperlipidemia
- Diabetes
- History of myocardial infarction or acute coronary syndrome
About this study
To determine if pre-race training effects heart damage induced by marathon running.
Read the detailed description
Investigations have shown increases in cardiac markers consistent with myocardial injury and left ventricular dysfunction in both recreational and elite athletes after endurance exercise. Pre-race training is an important component of endurance events, yet its effect on cardiovascular injury is unclear. The present study aimed to evaluate the correlation between myocardial injury and training level in recreational marathon runners utilizing both objective and subjective measures.
- Conditions
- Troponin, Natriuretic Peptide, Brain, Exercise, Echocardiography
- Keywords
- Troponin, Natriuretic Peptide, Brain, Exercise, Echocardiography
- Medical subject headings
- Motor Activity
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Nov 2007 (estimated)
- Study startJan 2006
- Study completionOct 2006
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for TroponinStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Time perspective
- Prospective
- Enrolment
- 53 participants (actual)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Collaborators
- Abbott Point of Care
- Investigators
- Suzanne M Miller, MD, Principal investigator, Stanford Hospital and Clinics
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00560040
- Sponsor's protocol ID
- Miller 01
- Status last verified
- May 2007
- First submitted
- 15 Nov 2007
- Last updated
- 19 Nov 2007
- Results posted
- No
- Data monitoring committee
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 19 Nov 2007. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Myocardial Injury is Not Related to Training Levels Among Recreational Participants in the Silicon Valley Marathon
- ClinicalTrials.gov ID
- NCT00560040
- Acronym / sponsor ID
- Miller 01
- Conditions
- Troponin, Natriuretic Peptide, Brain, Exercise, Echocardiography
- Keywords
- Troponin, Natriuretic Peptide, Brain, Exercise, Echocardiography
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 53 participants (actual)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Collaborators
- Abbott Point of Care
- Study start
- Jan 2006
- Study completion
- Oct 2006 (actual)
- First posted
- 19 Nov 2007 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To determine if pre-race training effects heart damage induced by marathon running.
Detailed description
Investigations have shown increases in cardiac markers consistent with myocardial injury and left ventricular dysfunction in both recreational and elite athletes after endurance exercise. Pre-race training is an important component of endurance events, yet its effect on cardiovascular injury is unclear. The present study aimed to evaluate the correlation between myocardial injury and training level in recreational marathon runners utilizing both objective and subjective measures.
Study design
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- Any healthy male or female aged 18-65 planning to run the 2006 Silicon Valley Marathon.
Key exclusion criteria (4 listed)
- Hypertension
- Hyperlipidemia
- Diabetes
- History of myocardial infarction or acute coronary syndrome
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Nov 2007.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Suzanne M Miller, MD principal investigator
Stanford Hospital and Clinics
Questions about this trial
What is this clinical trial studying?
An observational study of Troponin and Natriuretic Peptide, Brain, run by Stanford University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Nov 2007. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Nov 2007.