Medication ErrorsNCT00603070
Electronic Prescribing and Electronic Transmission of Discharge Medication Lists
An observational study of Medication Errors, run by Weill Medical College of Cornell University at 1 site in United States.
Trial summary
The purpose of this study is twofold: 1. to measure the effects of transitioning from one electronic prescribing system to another in the ambulatory setting on medication errors and human-computer interactions 2. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Medication Errors
- What is being tested?
- E-prescribing system and Electronic transmission of medication discharge lists
- How many people
- 130 participants
- Where
- 1 siteUnited States
- Study dates
- Mar 2008to Mar 2011
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Physicians and Nurse Practitioners from 2 office practices in the Ambulatory Care Network at NYPH, Associates in Internal Medicine (AIM) on the Columbia campus and Cornell Internal Medicine Associates (CIMA) on the Cornell campus.
Who may be able to join
- Physicians or nurse practitioners with at least 4 clinic sessions per week
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country.
United States1 site
Weill Cornell Internal Medicine Associates
New York, New York, 10021
About this study
Official title: Electronic Prescribing and Electronic Transmission of Discharge Medication Lists to Improve Ambulatory Medication Safety
The purpose of this study is twofold:
- to measure the effects of transitioning from one electronic prescribing system to another in the ambulatory setting on medication errors and human-computer interactions
- to evaluate the impact of electronic transmission of discharge medication lists to the ambulatory setting on medication discrepancies and adverse drug events
- Conditions
- Medication Errors
- Being tested
- E-prescribing system, Electronic transmission of medication discharge lists
- Keywords
- Medication Errors, Adverse Drug Events, Patient Safety, Electronic Prescribing Systems, Medication Reconciliation
- Medical subject headings
- Drug-Related Side Effects and Adverse Reactions
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
E-prescribing systemOther
Also called WebCIS, CLIMACS, EpicCare, Eclypsis
Transition from home-grown to vendor-based ambulatory e-prescribing systems
Electronic transmission of medication discharge listsOther
Patient discharge medication lists will be transmitted upon discharge from their inpatient medical record to their outpatient medical record and their outpatient provider will be notified of this transmission.
| Study group | Role | What they receive |
|---|---|---|
| 1 | All physicians and nurse practitioners at 1 ambulatory care clinics Receives: Other: E-prescribing system | |
| 2 | All physicians and nurse practitioners at 1 ambulatory care clinics Receives: Other: Electronic transmission of medication discharge lists |
What is being measured
The primary outcome is the main question the study is designed to answer.
Prescription medication errors
Measured: 2 weeks prior, 3 months, 1 year after intervention and 2 years after intervention
Medication discrepancies (as detected on a comparison between inpatient and outpatient medical records)
Measured: 30 days after patient is discharged from hospital
Patient adverse drug events (as determined by patient telephone interview and medical record review)
Measured: 30 days after patient hospital discharge
Secondary outcomes (1)
Human-Computer interactions as measured by physician interview and direct observation of physician work
Measured: 3 months after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jan 2008 (estimated)
- Study startMar 2008
- Primary completionMar 2011
- Study completionMar 2011
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Medication ErrorsStudies of the same condition, open and under way.
- More trials run by Weill Medical College of Cornell UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 130 participants (actual)
Sponsor and investigators
- Lead sponsor
- Weill Medical College of Cornell University
- Sponsor type
- University, hospital or other
- Collaborators
- Agency for Healthcare Research and Quality (AHRQ), New York Presbyterian Hospital, Columbia University, Oregon Health and Science University
- Responsible party
- Sponsor
- Investigators
- Rainu Kaushal, MD, MPH, Principal investigator, Weill Medical College of Cornell University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00603070
- Sponsor's protocol ID
- R18HS017029-01
- Status last verified
- Feb 2012
- First submitted
- 15 Jan 2008
- Last updated
- 20 Feb 2012
- Results posted
- No
- Data monitoring committee
- No
Publications
Abramson EL, Malhotra S, Osorio SN, Edwards A, Cheriff A, Cole C, Kaushal R. A long-term follow-up evaluation of electronic health record prescribing safety. J Am Med Inform Assoc. 2013 Jun;20(e1):e52-8. doi: 10.1136/amiajnl-2012-001328. Epub 2013 Apr 11.
PubMed 23578816Abramson EL, Patel V, Malhotra S, Pfoh ER, Nena Osorio S, Cheriff A, Cole CL, Bunce A, Ash J, Kaushal R. Physician experiences transitioning between an older versus newer electronic health record for electronic prescribing. Int J Med Inform. 2012 Aug;81(8):539-48. doi: 10.1016/j.ijmedinf.2012.02.010. Epub 2012 Mar 30.
PubMed 22465355Abramson EL, Malhotra S, Fischer K, Edwards A, Pfoh ER, Osorio SN, Cheriff A, Kaushal R. Transitioning between electronic health records: effects on ambulatory prescribing safety. J Gen Intern Med. 2011 Aug;26(8):868-74. doi: 10.1007/s11606-011-1703-z. Epub 2011 Apr 16.
PubMed 21499828
Study at a glance
From the registry record, last updated by the sponsor on 20 Feb 2012. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Electronic Prescribing and Electronic Transmission of Discharge Medication Lists to Improve Ambulatory Medication Safety
- ClinicalTrials.gov ID
- NCT00603070
- Acronym / sponsor ID
- R18HS017029-01
- Conditions
- Medication Errors
- Keywords
- Medication Errors, Adverse Drug Events, Patient Safety, Electronic Prescribing Systems, Medication Reconciliation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 130 participants (actual)
- Lead sponsor
- Weill Medical College of Cornell UniversityUniversity, hospital or other
- Collaborators
- Agency for Healthcare Research and Quality (AHRQ), New York Presbyterian Hospital, Columbia University, Oregon Health and Science University
- Study start
- Mar 2008
- Primary completion
- Mar 2011 (actual)
- Study completion
- Mar 2011 (actual)
- First posted
- 28 Jan 2008 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is twofold:
- to measure the effects of transitioning from one electronic prescribing system to another in the ambulatory setting on medication errors and human-computer interactions
- to evaluate the impact of electronic transmission of discharge medication lists to the ambulatory setting on medication discrepancies and adverse drug events
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| 1 | – | Other: E-prescribing systemAll physicians and nurse practitioners at 1 ambulatory care clinics |
| 2 | – | Other: Electronic transmission of medication discharge listsAll physicians and nurse practitioners at 1 ambulatory care clinics |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Physicians and Nurse Practitioners from 2 office practices in the Ambulatory Care Network at NYPH, Associates in Internal Medicine (AIM) on the Columbia campus and Cornell Internal Medicine Associates (CIMA) on the Cornell campus.
Key inclusion criteria (1 listed)
- Physicians or nurse practitioners with at least 4 clinic sessions per week
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| E-prescribing systemAlso: WebCIS, CLIMACS, EpicCare, EclypsisTransition from home-grown to vendor-based ambulatory e-prescribing systems | Other | 1 |
| Electronic transmission of medication discharge listsPatient discharge medication lists will be transmitted upon discharge from their inpatient medical record to their outpatient medical record and their outpatient provider will be notified of this transmission. | Other | 2 |
Primary outcome
Prescription medication errors
Time frame: 2 weeks prior, 3 months, 1 year after intervention and 2 years after intervention
Medication discrepancies (as detected on a comparison between inpatient and outpatient medical records)
Time frame: 30 days after patient is discharged from hospital
Patient adverse drug events (as determined by patient telephone interview and medical record review)
Time frame: 30 days after patient hospital discharge
1 secondary outcome
Human-Computer interactions as measured by physician interview and direct observation of physician work
Time frame: 3 months after intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Feb 2012.
- Derived from this study: PubMed 23578816Abramson EL, Malhotra S, Osorio SN, Edwards A, Cheriff A, Cole C, Kaushal R. A long-term follow-up evaluation of electronic health record prescribing safety. J Am Med Inform Assoc. 2013 Jun;20(e1):e52-8. doi: 10.1136/amiajnl-2012-001328. Epub 2013 Apr 11.
- Derived from this study: PubMed 22465355Abramson EL, Patel V, Malhotra S, Pfoh ER, Nena Osorio S, Cheriff A, Cole CL, Bunce A, Ash J, Kaushal R. Physician experiences transitioning between an older versus newer electronic health record for electronic prescribing. Int J Med Inform. 2012 Aug;81(8):539-48. doi: 10.1016/j.ijmedinf.2012.02.010. Epub 2012 Mar 30.
- Derived from this study: PubMed 21499828Abramson EL, Malhotra S, Fischer K, Edwards A, Pfoh ER, Osorio SN, Cheriff A, Kaushal R. Transitioning between electronic health records: effects on ambulatory prescribing safety. J Gen Intern Med. 2011 Aug;26(8):868-74. doi: 10.1007/s11606-011-1703-z. Epub 2011 Apr 16.
Related trials for Medication Errors
Active, not recruitingPhase 2
MT2013-31: Allo HCT for Metabolic Disorders and Severe Osteopetrosis
Mucopolysaccharidosis Disorders, Hurler Syndrome
RecruitingObservational study
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
Rare Disorders, Undiagnosed Disorders
Not yet recruitingObservational study
A Survey to Assess Participants', Caregivers', and Nurses' Use and Understanding of Educational Material on Velaglucerase Alfa (VPRIV) Home Infusion
Gaucher Disease
RecruitingObservational study
Pompe Disease RWE Long-term Monitoring Program
Pompe Disease
Active, not recruitingPhase 2/3
A Multi-cohort Study of Safety, Efficacy, PK and PD of GNR-055 in Patients With Mucopolysaccharidosis Type II
Mucopolysaccharidosis Type II, Metabolic Diseases
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Rainu Kaushal, MD, MPH principal investigator
Weill Medical College of Cornell University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Medication Errors, run by Weill Medical College of Cornell University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Feb 2012. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Prescription medication errors (time frame: 2 weeks prior, 3 months, 1 year after intervention and 2 years after intervention). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00603070, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Feb 2012.