AzTrials
AzTrials

Chronic Plaque PsoriasisNCT00799877

Chronic Plaque Psoriasis (Ps) Registry

An observational study of Chronic Plaque Psoriasis, run by AbbVie at 339 sites in 14 countries.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

The purpose of this study is to evaluate the long-term safety of Humira® in Adult Patients with Chronic Plaque Psoriasis (Ps). Read more about this study

Who is it for?
Ages 18 to 99 years
Conditions the study is for
Chronic Plaque Psoriasis
How many people
6,065 participants
Where
339 sitesin 14 countries
Study dates
26 Sep 2008to 13 Feb 2023
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 99 years
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Study population: primary care clinic, departments of dermatology

Who may be able to join

  • An adult patient (18 years of age or older) with chronic plaque psoriasis who has been prescribed HUMIRA® therapy according to the local product labeling and meets one of the following criteria:
  • New initiated (within 4 weeks of registry entry) on HUMIRA® therapy;
  • Initiated HUMIRA® therapy in the past and:
  • Has received continuous (no more than 70 consecutive days off drug) HUMIRA® therapy and the physician can provide source documentation of SAEs, AEs, of Special Interest, and dosing information since initiation of therapy.
  • OR
  • Is entering after participation in an AbbVie HUMIRA (adalimumab) sponsored study and has received continuous (no more than 70 consecutive days off drug) HUMIRA® therapy after the completion of AbbVie sponsored study and physician can provide source documentation of SAEs, AEs of Special Interest, and dosing information since initiation of commercial HUMIRA® (defined as a prescribed/non study drug).
  • Patient is willing to consent to data being collected and provided to AbbVie;
  • Patient is capable of and willing to give written informed consent and to comply with the requirements of the registry.

Who cannot join

  • Patient should not be enrolled if he/she cannot be treated in accordance with the local product label.

Trial locations and contacts

339 sites in 14 countries.

339 sites in 14 countries

United States222 sites

  • Hawkins, Akron, Ohio /ID# 28149

    Akron, Ohio, 44313

  • Summa Physicians Dermatology /ID# 37051

    Akron, Ohio, 44320

  • Hamilton Research, LLC /ID# 20503

    Alpharetta, Georgia, 30022

  • David Fivenson, MD, PLC /ID# 20504

    Ann Arbor, Michigan, 48103

  • Anapolis Dermatology Center /ID# 24302

    Annapolis, Maryland, 21409

  • Dermatology Assoc of WI /ID# 28142

    Appleton, Wisconsin, 54913

  • Arlington Research Center, Inc /ID# 23063

    Arlington, Texas, 76011

  • Premier Dermatology /ID# 69958

    Ashburn, Virginia, 20147-5667

  • Oakview Dermatology, LLC /ID# 38298

    Athens, Ohio, 45701-2866

  • Parker, Atlanta, GA /ID# 40190

    Atlanta, Georgia, 30322-1013

  • Reflections Dermatology & Psoriasis canter /ID# 19781

    Auburn, New York, 13021

  • Austin Dermatology Associates /ID# 38296

    Austin, Texas, 78705

  • Steiner Ranch Dermatology /ID# 20509

    Austin, Texas, 78732-6067

  • Austintown /ID# 76121

    Austintown, Ohio, 44515

  • Private Practice- Dr. Tory Sullivan /ID# 17126

    Aventura, Florida, 33180

  • MidSouth Dermatology /ID# 17128

    Bartlett, Tennessee, 38134

  • The Dermatology Center, PSC - Bayside NY /ID# 28170

    Bayside, New York, 11360

  • Mikell, Beaufort, SC /ID# 17143

    Beaufort, South Carolina, 29902

  • Belleville Dermatology Center /ID# 17067

    Belleville, New Jersey, 07109

  • Dermatology & Laser Center NW /ID# 18324

    Bellingham, Washington, 98225

  • Glassman, Bethesda, MD /ID# 17069

    Bethesda, Maryland, 20817

  • Southview Medical Group, PC /ID# 20961

    Birmingham, Alabama, 35205

  • Total Skin and Beauty Derm Ctr /ID# 17156

    Birmingham, Alabama, 35205

  • Inverness Dermatology /ID# 76194

    Birmingham, Alabama, 35242

  • McLain Medical Associates, PC /ID# 18351

    Birmingham, Alabama, 35242

  • Wray, Blackfoot, ID /ID# 24333

    Blackfoot, Idaho, 83221

  • Brigham Dermatology Associates /ID# 28207

    Boston, Massachusetts, 02115

  • Moss and Maiocco, MD, LLC /ID# 69767

    Bridgeport, Connecticut, 06606

  • Saoud, Bridgeport, WV /ID# 17135

    Bridgeport, West Virginia, 26330

  • Skin Cancer & Cosmetic Derm Ct /ID# 23313

    Calhoun, Georgia, 30701

  • Shideler Dermatology Group /ID# 69957

    Carmel, Indiana, 46032

  • Dermatology and Skin Surgery /ID# 88353

    Celebration, Florida, 34747

  • Central Dermatology Center, PA /ID# 17070

    Chapel Hill, North Carolina, 27517-8913

  • Dr. Aida Lugo-Somolinos /ID# 24309

    Chapel Hill, North Carolina, 92037

  • Hampton, Charleston, NC /ID# 18865

    Charleston, South Carolina, 29407

  • Coastal Clinical Research Center of the Carolinas /ID# 18353

    Charleston, South Carolina, 29414

  • Fraser, Charlotte, NC /ID# 19772

    Charlotte, North Carolina, 28207

  • Pinski Dermatology /ID# 17147

    Chicago, Illinois, 60602

  • Northwestern University Feinberg School of Medicine /ID# 28169

    Chicago, Illinois, 60611-2927

  • John H. Stroger, Jr. Hosp /ID# 40185

    Chicago, Illinois, 60612-9985

  • Rush University Medical Center /ID# 47604

    Chicago, Illinois, 60612

  • Del Campo, Chicago, IL /ID# 19770

    Chicago, Illinois, 60641

  • Idaho Skin Institute /ID# 76118

    Chubbuck, Idaho, 83202

  • Mountain State Clinical Research /ID# 28146

    Clarksburg, West Virginia, 26301

  • Skin Cancer & Cosmetic Derm /ID# 65882

    Cleveland, Tennessee, 37311

  • Iacobelli, Clinton Twnshp, MI /ID# 38290

    Clinton Township, Michigan, 48038

  • Colorado Springs Derm Clinic /ID# 28165

    Colorado Springs, Colorado, 80910

  • The Ohio State University /ID# 43150

    Columbus, Ohio, 43210

  • East Metro Dermatology PC /ID# 20505

    Conyers, Georgia, 30012

  • Florida Academic Centers Research and Education /ID# 24273

    Coral Gables, Florida, 33134

  • Knuckles, Corbin, KY /ID# 17101

    Corbin, Kentucky, 40701

  • Spencer Dermatology Associates /ID# 71678

    Crawfordsville, Indiana, 47933

  • Dermatology Treatment and Research Center /ID# 17545

    Dallas, Texas, 75230

  • Aftergut, Dallas, TX /ID# 17041

    Dallas, Texas, 75237

  • Texas Dermatology Associates /ID# 28155

    Dallas, Texas, 75246

  • Texas Dermatology Associates /ID# 28157

    Dallas, Texas, 75246

  • Notaro, Danbury, CT /ID# 40264

    Danbury, Connecticut, 06810

  • Derm Assoc of Western CT /ID# 71673

    Danbury, Connecticut, 23454

  • Elite MD Adv Derm Laser /ID# 28323

    Danville, California, 94526

  • Deep South Dermatology, PC /ID# 40267

    Daphne, Alabama, 36526

  • Dermatology Associates of the Palm Beaches /ID# 17137

    Delray Beach, Florida, 33486

  • Altoona Ctr Clinical Res /ID# 17155

    Duncansville, Pennsylvania, 16635

  • Duke Cancer Center /ID# 24324

    Durham, North Carolina, 27710-3000

  • Psoriasis Treatment Center of Central New Jersey /ID# 17148

    East Windsor, New Jersey, 08520

  • Allied Dermatology and Skin Surgery /ID# 28154

    Fairlawn, Ohio, 44333-4510

  • Hamzavi Dermatology /ID# 25903

    Fort Gratiot, Michigan, 48059

  • Ft. Lauderdale Derm & Cosmetic /ID# 23071

    Fort Lauderdale, Florida, 33308

  • Johnson Dermatology Clinic /ID# 17088

    Fort Smith, Arkansas, 72916-6103

  • Center for Dermatology Clinical Research /ID# 20722

    Fremont, California, 94538

  • Associates in Research /ID# 17544

    Fresno, California, 93720

  • Garden City Dermatology /ID# 42003

    Garden City, New York, 11530

  • Dermatology and Dermatologic /ID# 17145

    Garden Grove, California, 92843

  • Guagenti, Glendale, CA /ID# 28263

    Glendale, California, 91204

  • Pinnacle Dermatology - Grand Blanc /ID# 40196

    Grand Blanc, Michigan, 48439-2443

  • Stawiski, Grand Rapids, MI /ID# 17124

    Grand Rapids, Michigan, 49503

  • Piedmont Dermatology Center /ID# 18326

    Greensboro, North Carolina, 27408

  • Schwartz,Harlingen,TX,US /ID# 20725

    Harlingen, Texas, 78550-8255

  • Great Plains Dermatology, P.A. /ID# 23079

    Hays, Kansas, 67601

  • Assoc. Derm & Skin Cancer Clin /ID# 24303

    Helena, Montana, 59601

  • Academic Dermatology of Nevada /ID# 20513

    Henderson, Nevada, 89052

  • Fernandez-Obregon, Hoboken, NJ /ID# 23073

    Hoboken, New Jersey, 07030

  • Hollywood Dermatology /ID# 17129

    Hollywood, Florida, 33021

  • Hollywood Dermatology /ID# 19771

    Hollywood, Florida, 33021

  • Sonabend, Houston, TX /ID# 17123

    Houston, Texas, 77005

  • Heights Dermatology & Aesthetic Center /ID# 28325

    Houston, Texas, 77008

  • Memorial Clinical Associates /ID# 17085

    Houston, Texas, 77079

  • West Houston Dermatology /ID# 18330

    Houston, Texas, 77082

  • Northeast Alabama Dermatology /ID# 76193

    Huntsville, Alabama, 35801

  • Yates, Huntsville, AL /ID# 17130

    Huntsville, Alabama, 35801

  • Indiana University /ID# 37052

    Indianapolis, Indiana, 46202

  • Dawes Fretzin, LLC /ID# 17151

    Indianapolis, Indiana, 46256

  • Dawes Fretzin, LLC /ID# 17502

    Indianapolis, Indiana, 46256

  • Dermatology Associates of Indiana /ID# 24269

    Indianapolis, Indiana, 46260

  • Dermatology Associates /ID# 42008

    Kingsport, Tennessee, 37660

  • Miremadi Dermatology /ID# 24323

    La Jolla, California, 92037

  • SCRIPPS Clinic /ID# 28147

    La Mesa, California, 91941

  • Linda Woodson Dermatology /ID# 18333

    Las Vegas, Nevada, 89128-0652

  • Nathan Adelson Hospice /ID# 18332

    Las Vegas, Nevada, 89128

  • Bruckstein, Lawrence, NY /ID# 17063

    Lawrence, New York, 11559

  • Dartmouth-Hitchcock Medical Center /ID# 20502

    Lebanon, New Hampshire, 03756

  • Suncoast Dermatology and Skin Surgery Center /ID# 23067

    Lecanto, Florida, 34461

  • Lakeside Dermatology /ID# 247839

    Libertyville, Illinois, 60048-1307

  • Dr. Abdallah Khourdaji /ID# 24307

    Lodi, California, 95242

  • Premiere Clinical Research,LLC /ID# 44719

    Long Beach, California, 90712

  • Skin Care Specialists of CO /ID# 17142

    Longmont, Colorado, 80501

  • Kaiser Permanente LA Med Ctr /ID# 24334

    Los Angeles, California, 90027

  • Dermatology Research Associates /ID# 17158

    Los Angeles, California, 90045

  • Lehman Dermatology Clinic /ID# 17082

    Lubbock, Texas, 79410

  • Texas Tech University Health Sciences Center - Lubbock /ID# 37050

    Lubbock, Texas, 79430

  • Dermatologic Surgery Specialis /ID# 17149

    Macon, Georgia, 31217

  • NW GA Dermatology & Skin Cancer Specialists /ID# 17089

    Marietta, Georgia, 30060

  • Paula Nelson MD & Associates /ID# 23076

    Marietta, Georgia, 30067

  • Loyola University Medical Ctr /ID# 23065

    Maywood, Illinois, 60153

  • The Dermatology Inst of S. TX /ID# 38288

    McAllen, Texas, 78501

  • Athenea Assoc Med Research /ID# 69768

    Miami, Florida, 33126

  • Mobile Dermatology, P.C. /ID# 19783

    Mobile, Alabama, 36609

  • Hardy County Medical /ID# 28264

    Moorefield, West Virginia, 26836

  • Fulk, Morristown, TN /ID# 18344

    Morristown, New Jersey, 37814

  • California Skin Institute /ID# 19769

    Mountain View, California, 94040

  • Saltzer Medical Group /ID# 17144

    Nampa, Idaho, 83687

  • Assoc. in Med & Surg Derm /ID# 17523

    Naples, Florida, 34109

  • Nashua Dermatology /ID# 18352

    Nashua, New Hampshire, 03060-3956

  • The Dermatology Center PSC - New Albany /ID# 20501

    New Albany, Indiana, 47150

  • Dermatology Associates of Coastal Carolina /ID# 76116

    New Bern, North Carolina, 28560

  • Choi, New Haven, CT /ID# 58982

    New Haven, Connecticut, 06510

  • Scheinfeld, New York, NY /ID# 17136

    New York, New York, 10019

  • New York Presbyterian Hospital Weill Cornell Medical Center /ID# 24268

    New York, New York, 10065

  • Panzer Dermatology & Cosmetic /ID# 17131

    Newark, Delaware, 19713

  • Panzer Dermatology & Cosmetic /ID# 17146

    Newark, Delaware, 19713

  • RI Dermatology & Cosmetic Ctr /ID# 40270

    Newport, Georgia, 02840

  • Quest Dermatology Research /ID# 71677

    Northridge, California, 91324-4663

  • Lakeshore Dermatology /ID# 24330

    Norton Shores, Michigan, 49444-7831

  • South Nassau Dermatology /ID# 17065

    Oceanside, New York, 11572

  • Univ Oklahoma HSC /ID# 28145

    Oklahoma City, Oklahoma, 73104

  • Center of Dermatology, P.C. /ID# 23078

    Omaha, Nebraska, 68114

  • Central Florida Dermatology Associates /ID# 20508

    Orlando, Florida, 32806

  • Epiphany Dermatology of Kansas LLC /ID# 19764

    Overland Park, Kansas, 66210

  • Dermatology Medical Group of Oxnard /ID# 17102

    Oxnard, California, 93030

  • Gulf Coast Dermatology /ID# 20724

    Panama City, Florida, 32405

  • Snyder, Pembroke Pines, FL /ID# 17122

    Pembroke Pines, Florida, 33028

  • Medical Dermatology Specialist /ID# 76113

    Phoenix, Arizona, 85006-2722

  • Arizona Advanced Dermatology /ID# 20512

    Phoenix, Arizona, 85014

  • Camelback Dermatology & Skin Surgery /ID# 18901

    Phoenix, Arizona, 85018

  • Alliance Dermatology and MOHs Center, PC /ID# 17087

    Phoenix, Arizona, 85032

  • Omni Dermatology Research /ID# 135562

    Phoenix, Arizona, 85108

  • Carolina Skin Care /ID# 19773

    Pinehurst, North Carolina, 28374

  • Gary L. Heller - Dermatology Research Cosmetic Center /ID# 17083

    Pinellas Park, Florida, 33781

  • University of Pittsburgh MC /ID# 17068

    Pittsburgh, Pennsylvania, 15260

  • The Indiana Clinical Trials Center /ID# 17153

    Plainfield, Indiana, 46168

  • Skin and Cancer Associates /ID# 20726

    Plantation, Florida, 33324-1857

  • Great Lakes Dermatology /ID# 17061

    Pleasant Prairie, Wisconsin, 53158

  • Great Lakes Dermatology /ID# 91433

    Pleasant Prairie, Wisconsin, 53158

  • Oregon Dermatology and Research Center /ID# 24327

    Portland, Oregon, 97210

  • Oregon Medical Research Center /ID# 28143

    Portland, Oregon, 97239

  • Andrus and Assoc Dermatology /ID# 20510

    Raleigh, North Carolina, 27609

  • Riley, Reno, NV /ID# 36343

    Reno, Nevada, 89509

  • Aylesworth, Rhinelander, WI /ID# 18322

    Rhinelander, Wisconsin, 54501

  • The Ctr for Derm at Lifetime /ID# 47603

    Rochester, New York, 14623

  • Dermatology and Skin Cancer Specialists, LLC /ID# 65884

    Rockville, Maryland, 20850

  • Boice-Willis Clinic, P.A. /ID# 17125

    Rocky Mount, North Carolina, 27804

  • Hull Dermatology, PA /ID# 17086

    Rogers, Arkansas, 72758

  • Arlington Dermatology /ID# 23062

    Rolling Meadows, Illinois, 60008

  • Skin Cancer & Cosmetic Derm /ID# 24305

    Rome, Georgia, 30161

  • Northwest Georgia Dermatology /ID# 28162

    Rome, Georgia, 30165

  • Dermatology Associates of San Antonio /ID# 17150

    San Antonio, Texas, 78258

  • Univ California, San Francisco /ID# 28267

    San Francisco, California, 94143-2204

  • Danesh, San Gabriel, CA /ID# 23068

    San Gabriel, California, 91776

  • Carson, San Jose, CA /ID# 17064

    San Jose, California, 95123

  • East Bay Psoriasis Trmnt Ctr /ID# 17081

    San Ramon, California, 94583

  • Redwood Family Dermatology /ID# 76119

    Santa Rosa, California, 95403

  • The Center for Skin Wellness /ID# 42005

    Sarasota, Florida, 34240

  • Schaumburg Dermatology, SC /ID# 38294

    Schaumburg, Illinois, 60173

  • Affiliated Dermatology /ID# 18327

    Scottsdale, Arizona, 85255

  • Dermatology Associates of Seattle /ID# 18328

    Seattle, Washington, 98101

  • Dermatology Associates of Seattle /ID# 19802

    Seattle, Washington, 98101

  • Shoreline Skin Specialists, SC /ID# 69771

    Sheboygan, Wisconsin, 53081-3043

  • Dermedx Dermatology, PC /ID# 28163

    Smithtown, New York, 11787

  • UMDNJ R. W. Johnson Med School /ID# 24326

    Somerset, New Jersey, 08873

  • Aspen Dermatology, PLLC /ID# 38293

    Spanish Fork, Utah, 84660

  • Aspen Dermatology, PLLC /ID# 40183

    Spanish Fork, Utah, 84660

  • Aspen Dermatology, PLLC /ID# 40192

    Spanish Fork, Utah, 84660

  • Westside Dermatology, LLC /ID# 17541

    Spartanburg, South Carolina, 29306

  • Premier Clinical Research /ID# 28168

    Spokane, Washington, 99202

  • St. Louis University /ID# 28150

    St Louis, Missouri, 63104

  • Metro Hypertension and Kidney /ID# 40184

    St Louis, Missouri, 63136

  • Dermatology Associates, Inc. /ID# 23075

    St Louis, Missouri, 63141

  • Water's Edge Dermatology - Stuart /ID# 76114

    Stuart, Florida, 34994

  • Derm Consultants of Summit /ID# 24308

    Summit, New Jersey, 07901-2571

  • Komorous, Tacoma, WA /ID# 42007

    Tacoma, Washington, 98405

  • Scannon, Tampa, Florida /ID# 28160

    Tampa, Florida, 33607

  • University of South Florida /ID# 38289

    Tampa, Florida, 33612

  • Ctr for Derm & Skin Surgery /ID# 28210

    Tampa, Florida, 33613

  • Geisinger Medical Center /ID# 17521

    Tampa, Florida, 33618

  • Tucker, The Woodlands, Texas /ID# 38295

    The Woodlands, Texas, 77380

  • Kansas Medical Clinic /ID# 28212

    Topeka, Kansas, 66614

  • Somerset Skin Centre /ID# 17157

    Troy, Michigan, 48084

  • Atlanta Derm & Laser Surgery /ID# 28144

    Tucker, Georgia, 30084

  • Specialists in Dermatology /ID# 18864

    Tucson, Arizona, 85712

  • Tulsa Dermatology Clinic, Inc. /ID# 71675

    Tulsa, Oklahoma, 74114

  • Olmstead, Twin Falls, ID /ID# 24325

    Twin Falls, Idaho, 83301

  • Skin and Laser Surgery Center /ID# 40182

    Tysons Corner, Virginia, 22182

  • Skin Physicians & Surgeons Med /ID# 40265

    Upland, California, 91786

  • Advanced Dermatology & Cosmetic Care /ID# 20511

    Valencia, California, 91355

  • Solano Dermatology Associates /ID# 20727

    Vallejo, California, 94590

  • Coast Derm & Skin Cancer Ctr /ID# 40189

    Venice, Florida, 34293

  • Heskel, Vero Beach, FL /ID# 69764

    Vero Beach, Florida, 32960

  • The Dermatology Group, PC /ID# 28158

    Verona, New Jersey, 07044

  • Tidewater Skin Care/Pathology /ID# 71674

    Virginia Beach, Virginia, 23454

  • Eastern Washington Dermatology /ID# 17542

    Walla Walla, Washington, 99362

  • Brodell Medical Inc. /ID# 24304

    Warren, Ohio, 44483

  • George Washington University Hospital /ID# 24270

    Washington D.C., District of Columbia, 20037-2342

  • DuPage Medical Group /ID# 18861

    Wheaton, Illinois, 60189-3801

  • DuPage Medical Group /ID# 20507

    Wheaton, Illinois, 60189-3801

  • Charles County Dermatology /ID# 18341

    White Plains, Maryland, 20695

  • Town Center Dermatology /ID# 28152

    Wildwood, Missouri, 63040

  • Crane, Wilmington, NC /ID# 17066

    Wilmington, North Carolina, 28401

  • Wilmington Dermatology Center /ID# 69763

    Wilmington, North Carolina, 28403

  • Polley Clinic of Dermatology /ID# 18334

    Wilson, North Carolina, 27893

  • PMG Research of Winston-Salem /ID# 17133

    Winston-Salem, North Carolina, 27103-3921

  • Mercy Woodstock Medical Center /ID# 40186

    Woodstock, Illinois, 60098

  • Worcester Dermatology Assoc. /ID# 37048

    Worcester, Massachusetts, 01698

  • Marcus, Wyckoff, NJ /ID# 23074

    Wyckoff, New Jersey, 07481

Other trials in United States

Canada28 sites

  • Kirk Barber Research, CA /ID# 24204

    Calgary, Alberta, T2G 1B1

  • Dr. Isabelle Delorme Inc. /ID# 79193

    Drummondville, Quebec, J2B 5L4

  • Stratica Medical /ID# 24266

    Edmonton, Alberta, T5K 1X3

  • Murray, Halifax, CA /ID# 24224

    Halifax, Nova Scotia, B3K 5R3

  • Dermatrials Research /ID# 18363

    Hamilton, Ontario, L8N 1Y2

  • The Guenther Dermatology Research Centre /ID# 79196

    London, Ontario, N6A 3H7

  • Lynderm Research Inc. /ID# 18362

    Markham, Ontario, L3P 1X2

  • Durondel C.P. Inc. /ID# 28136

    Moncton, New Brunswick, E1C 2Z3

  • Innovaderm Research Inc. /ID# 18866

    Montreal, Quebec, H2X 2V1

  • Entralogix Clinical Research /ID# 79194

    Newmarket, Ontario, L3Y 6P5

  • Entralogix Clinical Research /ID# 79197

    Newmarket, Ontario, L3Y 6P5

  • Bank on Beauty /ID# 24205

    Niagara Falls, Ontario, L2E 2R4

  • North Bay Dermatology Centre /ID# 28138

    North Bay, Ontario, P1B 3Z7

  • SKIN Centre for Dermatology /ID# 79195

    Peterborough, Ontario, K9J 5K2

  • Centre de Dermatologie Maizerets /ID# 20515

    Québec, Quebec, G1J 1X7

  • Centre de Recherche dermatologique du Quebec Metropolitain /ID# 18361

    Québec, Quebec, G1V 4X7

  • Karma Clinical Trials /ID# 37049

    St. John's, Newfoundland and Labrador, A1A 4Y3

  • Alpha Clinical Research Ctr. /ID# 20581

    St. John's, Newfoundland and Labrador, A1B 4S8

  • Nexus Clinical Research /ID# 79198

    St. John's, Newfoundland and Labrador, A1B 5E8

  • NewLab Clinical Research Inc. /ID# 18360

    St. John's, Newfoundland and Labrador, A1C 2H5

  • Dr. Chih-ho Hong Medical Inc. /ID# 40199

    Surrey, British Columbia, V3R 6A7

  • Enverus Medical Research /ID# 141448

    Surrey, British Columbia, V3V 0C6

  • Dr. Jensen Yeung Medicine Professional Corporation /ID# 28141

    Toronto, Ontario, M5S 1B2

  • University of British Columbia - Eye Care Centre, Vancouver General Hospital /ID# 24223

    Vancouver, British Columbia, V5Z 3N9

  • K. Papp Clinical Research /ID# 28137

    Waterloo, Ontario, N2J 1C4

  • Dr. Beatrice Wang /ID# 18359

    Westmount, Quebec, H3Z 2S6

  • XLR8 Medical Research /ID# 28140

    Windsor, Ontario, N8W 1E6

  • Winnipeg Clinic /ID# 37046

    Winnipeg, Manitoba, R3C 0N2

Other trials in Canada

France16 sites

  • CHRU de Besancon - Site Saint-Jacques /ID# 24202

    Besançon, 25030

  • CHRU Tours - Hopital Trousseau /ID# 28271

    Chambray-lès-Tours, 37170

  • CHRU Lille - Hopital Claude Huriez /ID# 37063

    Lille, Hauts-de-France, 59037

  • CHU Limoges - Dupuytren 1 /ID# 25904

    Limoges, Franche-Comte, 87042

  • AP-HM - Hopital Sainte Marguerite /ID# 28270

    Marseille, 13009

  • Hopital Fournier /ID# 27938

    Nancy, 54000

  • CHU de Nantes, Hotel Dieu -HME /ID# 27944

    Nantes, Pays de la Loire Region, 44000

  • Chu de Nice-Hopital L'Archet Ii /Id# 27936

    Nice, Alpes-Maritimes, 06200

  • AP-HP - Hopital Saint-Louis /ID# 24203

    Paris, 75010

  • CHU Bordeaux - Hopital Haut Leveque /ID# 27934

    Pessac, Gironde, 33604

  • HCL - Hopital Lyon Sud /ID# 156129

    Pierre-Bénite, Auvergne-Rhône-Alpes, 69495

  • HCL - Hopital Lyon Sud /ID# 27940

    Pierre-Bénite, Auvergne-Rhône-Alpes, 69495

  • Duplicate_CHU de la miletrie /ID# 25906

    Poitiers, Poitou-Charentes, 86021

  • CHU Reims - Hôpital Robert Debre /ID# 37064

    Reims, Marne, 51092

  • Hôpital Charles-Nicolle /ID# 22845

    Rouen, 76000

  • CHU de SAINT ETIENNE - Hopital Nord /ID# 27942

    Saint Priest EN Jarez, Pays de la Loire Region, 42270

Other trials in France

Austria11 sites

  • Medizinische Universitaet Graz /ID# 24263

    Graz, Styria, 8010

  • Duplicate_Medizinische Universitat Innsbruck,Universitatsklinik fur Innere Mediz /ID# 22844

    Innsbruck, 6020

  • Kepler Universitaetsklinikum GmbH /ID# 27922

    Linz, Upper Austria, 4021

  • Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 22843

    Salzburg, 5020

  • Duplicate_University Hospital St. Polten /ID# 22842

    Sankt Pölten, Lower Austria, 3100

  • Klinik Landstrasse /ID# 20603

    Vienna, State of Vienna, 1030

  • Dr. Harald Maier /ID# 27921

    Vienna, State of Vienna, 1060

  • Medizinische Universitaet Wien /ID# 18364

    Vienna, State of Vienna, 1090

  • Medizinische Universitaet Wien /ID# 211020

    Vienna, State of Vienna, 1090

  • Klinik Hietzing /ID# 17183

    Vienna, State of Vienna, 1130

  • Klinikum Wels-Grieskirchen GmbH /ID# 17543

    Wels, Upper Austria, 4600

Other trials in Austria

Greece11 sites

  • General Hospital Andreas Syggros /ID# 22847

    Athens, Attica, 16121

  • General Hospital Andreas Syggros /ID# 22848

    Athens, Attica, 16121

  • General Hospital Andreas Syggros /ID# 25905

    Athens, Attica, 16121

  • Duplicate_Hospital Errikos Ntynan /ID# 28272

    Athens, 11526

  • Naval Hospital of Crete /ID# 22849

    Crete, Chania, 73136

  • General Hospital of Giannitsa /ID# 27951

    Giannitsá, 58100

  • University General Hospital of Heraklion PA.G.N.I /ID# 27954

    Heraklion, Crete, 71500

  • General Hospital of Katerini /ID# 27953

    Katerini, 60100

  • Duplicate_Papageorgiou General Hospital Thessaloniki /ID# 28232

    Nea Efkarpia, Thessaloniki, 54603

  • Tzaneio general hospital of Piraeus /ID# 28237

    Piraeus, Attica, 18536

  • Thessaloniki hospital for skin and venereal diseases- Ippokrateio Thessaloniki /ID# 37068

    Thessaloniki, 54643

Other trials in Greece

Netherlands10 sites

  • Centrum Oosterwal /ID# 18349

    Alkmaar, 1817 MS

  • ZiekenhuisGroep Twente /ID# 18355

    Almelo, 7609 PP

  • Academisch Medisch Centrum /ID# 22850

    Amsterdam, 1105 AZ

  • Amphia Ziekenhuis /ID# 20461

    Breda, 4818 CK

  • Duplicate_Duplicate_Oosterschelde Ziekenhuis /ID# 20462

    Goes, 4462 RA

  • Spaarne Gasthuis /ID# 22851

    Haarlem, 2035 RC

  • Dijklander Ziekenhuis /ID# 18354

    Hoorn, North Holland, 1624 NP

  • Radboud Universitair Medisch Centrum /ID# 24265

    Nijmegen, Gelderland, 6525 GA

  • Erasmus Medisch Centrum /ID# 24264

    Rotterdam, South Holland, 3015 GD

  • Diaconessenhuis Voorburg /ID# 18868

    Voorburg, 2275 CX

Other trials in Netherlands

Czechia9 sites

  • Fakultni Nemocnice Brno /ID# 27927

    Brno, 625 00

  • Fakultni nemocnice u sv. Anny v Brne /ID# 37062

    Brno, 656 91

  • Fakultni nemocnice Hradec Kralove /ID# 40201

    Hradec Králové, 500 05

  • Fakultni nemocnice Olomouc /ID# 27930

    Olomouc, 779 00

  • Duplicate_Univ Hosp, Plzen, CZ /ID# 27924

    Pilsen, 305 99

  • Duplicate_Vseobecna fakultni nemoc Praze /ID# 25907

    Prague, 128 08

  • Duplicate_Vseobecna fakultni nemoc Praze /ID# 27933

    Prague, 128 08

  • Vseobecna fakultni nemocnice v Praze /ID# 28269

    Prague, 128 08

  • Krajska zdravotni a.s. Masarykova nemocnice v Usti nad Labem o.z. /ID# 27923

    Ústí nad Labem, 401 13

Other trials in Czechia

Germany9 sites

  • Klinikum Ruhr Univ Bochum /ID# 40200

    Bochum, 44791

  • Universitaetsklinikum Koeln /ID# 27950

    Cologne, North Rhine-Westphalia, 50937

  • Universitaetsklinikum Frankfurt /ID# 19801

    Frankfurt am Main, Hesse, 60590

  • Universitaetsklinik Heidelberg /ID# 20601

    Heidelberg, Baden-Wurttemberg, 69120

  • Universitaetsklinikum Jena /ID# 19765

    Jena, Thuringia, 07747

  • Universitaetsklinikum Schleswig-Holstein Campus Kiel /ID# 22846

    Kiel, Schleswig-Holstein, 24105

  • Universitaetsklinikum Leipzig /ID# 20604

    Leipzig, Saxony, 04103

  • Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz /ID# 37067

    Mainz, 55131

  • Universitaetsklinikum Muenster /ID# 37066

    Munster, Lower Saxony, 48149

Other trials in Germany

Spain9 sites

  • Hospital Universitario Fundacion Alcorcon /ID# 20723

    Alcorcón, Madrid, 28922

  • Hospital General Universitario de Alicante Doctor Balmis /ID# 20730

    Alicante, 03010

  • Hospital Universitario Germans Trias i Pujol /ID# 17152

    Badalona, Barcelona, 08916

  • Hospital Universitari Sagrat Cor - Grupo Quiron Salud /ID# 19767

    Barcelona, 08029

  • Hospital Clinic de Barcelona /ID# 19803

    Barcelona, 08036

  • Hospital Duran i Reynals /ID# 18348

    L'Hospitalet de Llobregat, Barcelona, 08907

  • Hospital Universitario de la Princesa /ID# 18867

    Madrid, 28006

  • Hospital Universitario 12 de Octubre /ID# 18365

    Madrid, 28041

  • Hospital Clinico Universitario Lozano Blesa /ID# 19763

    Zaragoza, 50009

Other trials in Spain

United Kingdom7 sites

  • NHS Grampian /ID# 37069

    Aberdeen, AB15 6RE

  • Cardiff & Vale University Health Board /ID# 40204

    Cardiff, Wales, CF14 4XN

  • NHS Greater Glasgow and Clyde /ID# 27956

    Glasgow, Scotland, G12 0XH

  • Leeds Teaching Hospitals NHS Trust /ID# 40202

    Leeds, LS9 7TF

  • The Royal Free London NHS Foundation Trust /ID# 40205

    London, London, City of, NW3 2QG

  • Guys and St Thomas NHS Foundation Trust /ID# 28273

    London, London, City of, SE1 9RT

  • Northern Care Alliance NHS Group /ID# 40203

    Manchester, M8 5RB

Other trials in United Kingdom

Denmark4 sites

  • Aarhus University Hospital /ID# 18357

    Aarhus N, Central Jutland, 8200

  • Bispebjerg and Frederiksberg Hospital /ID# 24271

    Copenhagen NV, Capital Region, 2400

  • Herlev Hospital /ID# 20602

    Herlev, Capital Region, 2730

  • Hudklinikken /ID# 20729

    Herning, 7400

Other trials in Denmark

Ireland1 site

  • St Vincent's University Hospital /ID# 43149

    Elm Park, Dublin, D04 T6F4

Other trials in Ireland

Puerto Rico1 site

  • Dr. Reinaldo Rosario Med Offic /ID# 24328

    San Juan, 00918

Other trials in Puerto Rico

Sweden1 site

  • Uppsala University Hospital /ID# 38283

    Uppsala, 75185

Other trials in Sweden

About this study

Official title: A 10-Year, Post-marketing, Observational Study to Assess Long Term Safety of HUMIRA® (Adalimumab) in Adult Patients With Chronic Plaque Psoriasis (PS)

The purpose of this study is to evaluate the long-term safety of Humira® in Adult Patients with Chronic Plaque Psoriasis (Ps).

Read the detailed description

ESPRIT is a 10 year registry of patients taking HUMIRA® for Psoriasis. Patients who volunteer to participate will be asked to provide information about their medical history and experiences with HUMIRA®. No registry specific testing will be performed. Patients will be asked to provide data on their experiences with HUMIRA® approximately every 6 months, or as determined by the study doctor. No drug will be provided as a result of participation in the registry. All treatment decisions are independent of participation in the registry.

Keywords
Psoriasis, Moderate Psoriasis, Severe Psoriasis, Chronic Plaque Psoriasis, Severe Chronic Plaque Psoriasis, Registry
Medical subject headings
Psoriasis

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT00799877
Study groupRoleWhat they receive
1This registry will evaluate the long-term safety and effectiveness of HUMIRA® as used in routine clinical practice.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Incidence of Serious Adverse Events

    Incidence of Adverse Events is calculated upon all events that occur during registry, during exposure to HUMIRA® prior to entry of registry, and in Health Care Provider process.

    Measured: Duration of study

  2. Incidence of Adverse Events of Special Interest

    Incidence of Adverse Events is calculated upon all events that occur during registry, during exposure to HUMIRA® prior to entry of registry, and in Health Care Provider process.

    Measured: Duration of study

  3. Adverse Events that lead to permanent discontinuation of HUMIRA®

    Incidence of Adverse Events that lead to permanent discontinuation of HUMIRA® is calculated upon all events that lead to permanent discontinuation of HUMIRA® during registry, during exposure to HUMIRA® prior to entry of registry, and in Health Care Provider process.

    Measured: Duration of study

Secondary outcomes (12)

  1. Health Care Utilization

    Measured: Duration of study

  2. Work Productivity and Activity Impairment Questionnaire: Specific Health Problem

    Measured: Duration of study

  3. Patient Global Assessment

    Measured: Duration of study

  4. Patient Health Question-9

    Measured: Duration of study

  5. Medical Outcomes Social Activities Scale

    Measured: Duration of study

  6. Patient reported outcome - Dermatology Life Quality Index

    Measured: Duration of study

  7. Census

    Measured: Duration of study

  8. Psoriasis Impact and Experience

    Measured: Duration of study

  9. Illness Cognition

    Measured: Duration of study

  10. Insurance Status

    Measured: Duration of study

  11. Rosenberg Self-Esteem Scale

    Measured: Duration of study

  12. Physician's Global Assessment

    Measured: Collected approximately every six months.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted1 Dec 2008 (estimated)
  2. Study start26 Sep 2008
  3. Primary completion13 Feb 2023
  4. Study completion13 Feb 2023

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Cohort
Time perspective
Prospective
Enrolment
6,065 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT00799877
Sponsor's protocol ID
P10-023
Status last verified
Mar 2024
First submitted
26 Nov 2008
Last updated
15 Mar 2024
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Publications

  • Lynde CW, Alam MS, Ohson K, Gagne-Henley A, Avadisian M, Vender RB. Enhanced Effectiveness of Adalimumab Compared to Topical/Traditional Systemic Agents in the Treatment of Moderate to Severe Plaque Psoriasis: Results from a Canadian Observational Epidemiologic Study (COMPLETE-PS). Dermatol Ther (Heidelb). 2022 Apr;12(4):921-931. doi: 10.1007/s13555-022-00703-3. Epub 2022 Mar 14.

    PubMed 35286612

  • Menter A, Thaci D, Wu JJ, Abramovits W, Kerdel F, Arikan D, Guo D, Ganguli A, Bereswill M, Camez A, Valdecantos WC. Long-Term Safety and Effectiveness of Adalimumab for Moderate to Severe Psoriasis: Results from 7-Year Interim Analysis of the ESPRIT Registry. Dermatol Ther (Heidelb). 2017 Sep;7(3):365-381. doi: 10.1007/s13555-017-0198-x. Epub 2017 Aug 16.

    PubMed 28815476

Questions about this trial

What is this clinical trial studying?

An observational study of Chronic Plaque Psoriasis, run by AbbVie at 339 sites in 14 countries.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 8 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 15 Mar 2024. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 339 sites in United States, Canada, France, Austria, Greece and 9 more countries. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Incidence of Serious Adverse Events (time frame: Duration of study). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT00799877, which also lists 2 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Mar 2024.

AzTrials uses cookies for analytics and advertising. You can accept or reject them; the site works either way. Privacy Policy.

Free account

Keep searching with a free account

You’ve used your 3 free searches for this session. Log in or create a free AzTrials account to keep searching clinical trials and save the ones you want to follow.

Create a free accountLog in