AddictiveAtt-1NCT00911846
Attitudes Towards Buprenorphine and Methadone
An observational study of Addictive and Opioids, run by Psychiatric University Hospital, Zurich at 1 site in Switzerland.
Trial summary
Main intention of this study is to find out whether there is a difference between the attitudes towards opioid- substitution of opioid dependent patients under substitution with methadone, buprenorphine or without substitution and their therapists Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- What is being tested?
- interview
- How many people
- 180 participants
- Where
- 1 siteSwitzerland
- Study dates
- May 2009to Jun 2010
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Patients of therapeutic communities, in- and out-patients and their therapists
Who may be able to join
- Age between 18 and 65 years
- Opioid-dependent with substitution with buprenorphine,
- methadone or without substitution
- Sufficient knowledge of German language
Who cannot join
- Inability to give informed consent
Trial locations and contacts
1 site in 1 country.
Switzerland1 site, 1 recruiting
- Recruiting
Psychiatric University Hospital
Zurich, Canton of Zurich, 8032
Ria Leisinger, MD, 0041 44 384 27 87, ria.leisinger@puk.zh.ch
Rudolf Stohler, MD, 0041 44 205 58 10, rudolf.stohler@puk.zh.ch
About this study
Official title: Attitudes of Patients With Opioid-Substitution and Their Therapists Towards and Buprenorphine and Methadone
Main intention of this study is to find out whether there is a difference between the attitudes towards opioid- substitution of opioid dependent patients under substitution with methadone, buprenorphine or without substitution and their therapists
Read the detailed description
Attitudes of patients and therapists can influence therapy success in both directions. Not much is known about patients' and their therapists' attitudes towards substitution medication. Our hypothesis is that the attitude towards buprenorphine is more positive than towards methadone even in patients taking methadone. Better knowledge about the influence of attitudes on treatment success could facilitate to adapt therapy to the patients' needs.
- Being tested
- interview
- Keywords
- opioid dependence substitution buprenorphine methadone, "substitution"
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
interviewOther
Also called questionnaire attitudes toward substitution
interview using questionnaires
| Study group | Role | What they receive |
|---|---|---|
| Buprenorphine | opioid-dependent patients with buprenorphine substitution Receives: Other: interview | |
| methadone | opioid-dependent patients substituted with methadone Receives: Other: interview | |
| no substitution | opioid-dependent patients without substitution Receives: Other: interview | |
| therapists | therapists of the patients Receives: Other: interview |
What is being measured
The primary outcome is the main question the study is designed to answer.
Attitude toward buprenorphine compared over the four groups
Measured: one time of measurement
Secondary outcomes (1)
Treatment success; Treatment conditions; Consumption of substances
Measured: one point of measurement
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Jun 2009 (estimated)
- Study startMay 2009
- Primary completionSep 2009 (estimated)
- Study completionJun 2010 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AddictiveStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 180 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Psychiatric University Hospital, Zurich
- Sponsor type
- University, hospital or other
- Investigators
- Lukas Boesch, PhD, Study chair, Psychiatric University Hospital, Zurich
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00911846
- Sponsor's protocol ID
- E-10/2009
- Acronym
- Att-1
- Status last verified
- May 2009
- First submitted
- 28 May 2009
- Last updated
- 2 Jun 2009
- Results posted
- No
- Data monitoring committee
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Jun 2009. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Attitudes of Patients With Opioid-Substitution and Their Therapists Towards and Buprenorphine and Methadone
- ClinicalTrials.gov ID
- NCT00911846
- Acronym / sponsor ID
- Att-1 / E-10/2009
- Keywords
- opioid dependence substitution buprenorphine methadone, "substitution"
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 180 participants (estimated)
- Lead sponsor
- Psychiatric University Hospital, ZurichUniversity, hospital or other
- Study start
- May 2009
- Primary completion
- Sep 2009 (estimated)
- Study completion
- Jun 2010 (estimated)
- First posted
- 2 Jun 2009 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Main intention of this study is to find out whether there is a difference between the attitudes towards opioid- substitution of opioid dependent patients under substitution with methadone, buprenorphine or without substitution and their therapists
Detailed description
Attitudes of patients and therapists can influence therapy success in both directions. Not much is known about patients' and their therapists' attitudes towards substitution medication. Our hypothesis is that the attitude towards buprenorphine is more positive than towards methadone even in patients taking methadone. Better knowledge about the influence of attitudes on treatment success could facilitate to adapt therapy to the patients' needs.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Buprenorphine | – | Other: interviewopioid-dependent patients with buprenorphine substitution |
| methadone | – | Other: interviewopioid-dependent patients substituted with methadone |
| no substitution | – | Other: interviewopioid-dependent patients without substitution |
| therapists | – | Other: interviewtherapists of the patients |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Patients of therapeutic communities, in- and out-patients and their therapists
Key inclusion criteria (4 listed)
- Age between 18 and 65 years
- Opioid-dependent with substitution with buprenorphine,
- methadone or without substitution
- Sufficient knowledge of German language
Key exclusion criteria (1 listed)
- Inability to give informed consent
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| interviewAlso: questionnaire attitudes toward substitutioninterview using questionnaires | Other | Buprenorphine, methadone, no substitution, therapists |
Primary outcome
Attitude toward buprenorphine compared over the four groups
Time frame: one time of measurement
1 secondary outcome
Treatment success; Treatment conditions; Consumption of substances
Time frame: one point of measurement
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Jun 2009.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Lukas Boesch, PhD study chair
Psychiatric University Hospital, Zurich
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Addictive and Opioids, run by Psychiatric University Hospital, Zurich at 1 site in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 2 Jun 2009. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Ria Leisinger, MD (0041 44 384 27 87, ria.leisinger@puk.zh.ch), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Attitude toward buprenorphine compared over the four groups (time frame: one time of measurement). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Jun 2009; AzTrials last refreshed its copy on 31 Oct 2026.