Clinical trials: Addictive
Tobacco Dependence
Tobacco Intervention in Buprenorphine Treatment
Drug addiction treatment patients, including those in treatment for opioid dependence, have a high rate of tobacco dependence, especially cigarette smoking.
- Trial name
- IBIS (NCT01350011)
- Testing
- Innovative System, Standard Treatment Control (STC)
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Prevention, Digital Health
Digital Detox Study
The Digital Detox study is designed as a randomized controlled trial (two unblinded parallel groups) to examine the effects of reducing smartphone screentime on mental health.
- Conditions
- Prevention, Digital Health, Smartphone Addiction
- Trial name
- RESET (NCT06910371)
- Testing
- smartphone screen time reduction
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Danube University Krems
Tobacco Use Disorder, Nicotine Dependence
The MATCH (Medication Aids for Tobacco Cessation and Health) Study
Clinically proven medications such as nicotine replacement therapy, bupropion and varenicline are available to help smokers quit but there are not widely used.
- Trial name
- MATCH (NCT02146911)
- Testing
- Bupropion, Varenicline, Weekly Motivational Emails
- Where
- Canada
- Volunteers
- 968 people
- Sponsor
- Centre for Addiction and Mental Health
Pregnancy
Social Media Withdrawal in Pregnancy: Effects on Maternal Mental Health and Misinformation
The goal of this clinical trial is to learn if restricting social media use with a hardware device can improve mental health and well-being during pregnancy.
- Trial name
- SWIPE LEFT (NCT07812506)
- Testing
- Brick device
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Sexual Addiction
Prevalence of Sexual Addiction in an Inmate Population at the Muret Detention Center in Haute-Garonne (PAS-CD)
Sexual addiction, also known as hypersexuality or compulsive sexuality, is a human sexual behavior that results in a continuous and persistent search for sexual pleasure.
- Trial name
- PAS-CD (NCT05483426)
- Testing
- semi-structured Interviews
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Federation Regionale de Recherche en Psychiatrie et Sante Mentale Occitanie
Addiction
Dopaminergic Modulation of Frontostriatal Function With a Dopamine Agonist and COMT Inhibitor
In this study, the investigators are looking at how people make decisions about reward-related items, both monetary and food related after taking either the dopamine agonist bromocriptine or the COMT inhibitor tolcapone, in…
- Trial name
- NCT02929485
- Testing
- Tolcapone, Bromocriptine
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Substance Use Disorders
Life-Skills Training Program: Its Effect on Self-efficacy Among Patients With Substance Use Disorders
The goal of this clinical trial is to evaluate the effect of life-skills training program on self-efficacy among patients with substance in purposive sample male participants diagnosed with substance use disorders, aged from 20…
- Trial name
- NCT07174960
- Testing
- Life-Skills Training Program
- Where
- 2 sites in Egypt
- Volunteers
- 45 people
- Sponsor
- Ain Shams University
Chronic Pain, Addiction
Study of the Characteristics of Chronic Pain in Patients With Addiction
It is described in the literature a higher prevalence of pain in patients with an addiction but there are few studies describing the pain profile of patients with use disorder.
- Trial name
- ADDICTALGO (NCT05976178)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Groupe Hospitalier de Bretagne Sud
Pediatric Obesity, Mobile Technology
An Addiction-Based Mobile Health Weight Loss Intervention With Coaching
The proposed multi-site randomized control trial (RCT) will test the effectiveness of an addiction-based weight loss intervention, embodied first as a smartphone app with telephone coaching and second as an identical approach…
- Conditions
- Pediatric Obesity, Mobile Technology, Addiction
- Trial name
- NCT03500835
- Testing
- App, Coaching, Clinic: Modified KidsNFitness
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- Children's Hospital Los Angeles
Smartphone Addiction, Students, Nursing
Motivational Interview Based Intervention Program on Smartphone Addiction and Sleep Quality
Smartphones are the technological devices of our age that are constantly evolving and whose use is becoming more widespread day by day.
- Trial name
- NCT06098274
- Testing
- Motivational interviewing program based on transtheoretical model
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mustafa Yumusak
Substance Use Disorders
Patient Centered Assessment and Substance Use Disorder Treatment Study (PCAST)
California counties are in the process of implementing a Centers for Medicare and Medicaid Services Medicaid 1115 Substance Use Disorder (SUD) demonstration.
- Trial name
- PCAST (NCT03486028)
- Testing
- Adherence to ASAM protocols, Non-adherence to ASAM protocols
- Where
- United States
- Volunteers
- 991 people
- Sponsor
- RTI International
Addiction, Opioid Use
Phase Ib/2a Drug-drug Interaction Study of a Combination of 45mg Dextromethorphan With 105 mg Bupropion
The overall goal of this project is to collect initial human data on the effects of novel compounds on safety (interactions with an opioid drug, e.g., buprenorphine) and early efficacy signals (subjective effects on negative…
- Conditions
- Addiction, Opioid Use, Substance Use Disorders, Opioid Use Disorder
- Trial name
- NCT05976646
- Testing
- Auvelity
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Virginia Commonwealth University
Addiction, Substance Use Disorders (SUD)
Group Activities to Support Addiction Recovery
The purpose of this study is to pilot the use of Holotropic Breathwork (HB) for individuals seeking to recover from addiction. The study will have two arms: A--for individuals in residential treatment programs, B--for individuals…
- Trial name
- NCT07071883
- Testing
- Holotropic breathwork, Multiple modality
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Nebraska
Internet Gaming Disorder
Cognitive Bias Modification Training on Internet Gaming Disorder
To investigate whether and how the CBM training will alleviate the symptoms of addiction in Internet gaming disorders.
- Trial name
- CBM&IGD (NCT03790527)
- Testing
- CBM training
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Beijing Normal University
Mental Health Wellness 1, Addiction
Finding Wellness in the Pandemic
There is an immediate need for population-level intervention research to address the impacts of the coronavirus disease 2019 (COVID-19) pandemic and its containment measures on mental health and substance use (MHSU).
- Conditions
- Mental Health Wellness 1, Addiction, Stress, Psychological, Covid19
- Trial name
- NCT04615741
- Testing
- Trauma Informed Yoga, Trauma Informed Psychotherapy
- Where
- Canada
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Smartphone Addiction, Neck Disability
Effect of Smartphone Addiction on Pregnancy
This study will investigate the effect of smartphone addiction on neck disability during pregnancy and its mediating role on stress. The study will be conducted between September 2023 and April 2024.
- Conditions
- Smartphone Addiction, Neck Disability, Stress
- Trial name
- NCT06725394
- Testing
- Filling out the survey
- Where
- Turkey (Türkiye)
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Addiction, Opioid-use Disorder
Comprehensive CBT (Cognitive Behavioral Therapy) Via reSET App
This research is being done to find out whether an app based cognitive behavior therapy called reSET improves the adherence to and outcome of buprenorphine treatment for opioid use disorder (OUD) in the setting of a Hub and Spoke…
- Trial name
- NCT03826966
- Testing
- reSET
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Milton S. Hershey Medical Center
Methamphetamine Dependence, Substance Abuse
Varenicline vs Placebo for the Treatment of Methamphetamine Dependence
Methamphetamine (MA) abuse is the fastest growing drug problem in the United States and is responsible for significant public health complications, including HIV infection.
- Conditions
- Methamphetamine Dependence, Substance Abuse, Methamphetamine Abuse
- Trial name
- RAVEN (NCT01011829)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Focus: Effects of Nicotine and Alcohol on Brain Circuits
Neural Mechanisms Underlying Nicotine and Alcohol Combinations
Nicotine and alcohol are frequently used together and their combined use contributes to more than half a million deaths each year, with more alcoholics dying from smoking-related diseases than from alcohol-related diseases.
- Trial name
- QfMRI (NCT02049268)
- Testing
- Nicotine + Alcohol
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Addiction, Addiction Disorders
Can Selfcompassion Training Reduce Alcohol Consumption in Patients With Alcohol Use Disosrder ?
The objective of this interventional study is to evaluate the effectiveness of the Mindful Self-Compassion (MSC) program in reducing alcohol consumption in a population of individuals with Alcohol Use Disorder (AUD), six months…
- Conditions
- Addiction, Addiction Disorders, Alcohol Use Disorders, Alcohol Dependence
- Trial name
- COMPAL (NCT07131124)
- Testing
- Mindful Self-Compassion program, Treatment As Usual (TAU) program
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Etablissement Public de Santé Barthélemy Durand