MemoryProMemNCT00913640
Prospective Memory in Parkinson's Disease
An observational study of Memory and Prospective Memory, run by Washington University School of Medicine at 1 site in United States.
Trial summary
The investigators tested whether prospective memory is impaired in individuals with Parkinson's Disease compared to controls using reliable and validated experimental measures. Also, the investigators assessed the impact of Parkinson's medication on prospective memory performance in PD to better estimate prospective… Read more about this study
- Who is it for?
- Ages 40 to 70 yearsHealthy volunteers can take part
- Conditions the study is for
- Memory, Prospective Memory, Parkinson's Disease
- How many people
- 52 participants
- Where
- 1 siteUnited States
- Study dates
- 18 Nov 2009to 27 Aug 2010
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 70 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Community Movement Disorder Clinic at Washington University St. Louis
Who may be able to join
- PD Group:
- Clinically definite PD
- 40-70 years old
- Hoehn and Yahr stage I,II,III
- Currently treated with Levodopa/carbidopa
- Control Group:
- 40-70 years old
- Spouses of PD Group preferred
Who cannot join
- PD Group and Control Group:
- Significant neurological problems
- Significant current psychiatric diagnoses
- Mini Mental Status Exam score < 24 (MMSE)
- Any significant abnormality on brain imaging
- MPTP exposure
- Control Participants met the same exclusion criteria described above as well as a biological family history of PD
Trial locations and contacts
1 site in 1 country.
United States1 site
Washington University School of Medicine
St Louis, Missouri, 63110
About this study
The investigators tested whether prospective memory is impaired in individuals with Parkinson's Disease compared to controls using reliable and validated experimental measures. Also, the investigators assessed the impact of Parkinson's medication on prospective memory performance in PD to better estimate prospective memory function in PD patients' everyday (chronically treated) life.
- Conditions
- Memory, Prospective Memory, Parkinson's Disease
- Keywords
- Prospective Memory Performance, Prospective Memory Outcome, Parkinson's Disease
- Medical subject headings
- Parkinson Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| PD Group | Not described | |
| Control Group | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Virtual Week
Prospective Memory Task; Score range is 0-100%, with higher scores being better performance.
Measured: One session at baseline.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Jun 2009 (estimated)
- Study start18 Nov 2009
- Primary completion27 Aug 2010
- Study completion27 Aug 2010
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for MemoryStudies of the same condition, open and under way.
- More trials run by Washington University School of MedicineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Enrolment
- 52 participants (actual)
Sponsor and investigators
- Lead sponsor
- Washington University School of Medicine
- Sponsor type
- University, hospital or other
- Collaborators
- National Institutes of Health (NIH)
- Responsible party
- Sponsor
- Investigators
- Tamara G Hershey, Ph.D., Principal investigator, Washington University School of Medicine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT00913640
- Sponsor's protocol ID
- 05-0203
- Acronym
- ProMem
- Status last verified
- May 2022
- First submitted
- 1 Jun 2009
- Last updated
- 6 May 2022
- Results posted
- No
- Data monitoring committee
- No
Publications
Foster ER, Rose NS, McDaniel MA, Rendell PG. Prospective memory in Parkinson disease during a virtual week: effects of both prospective and retrospective demands. Neuropsychology. 2013 Mar;27(2):170-81. doi: 10.1037/a0031946.
PubMed 23527645
Study at a glance
From the registry record, last updated by the sponsor on 6 May 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prospective Memory in Parkinson's Disease
- ClinicalTrials.gov ID
- NCT00913640
- Acronym / sponsor ID
- ProMem / 05-0203
- Conditions
- Memory, Prospective Memory, Parkinson's Disease
- Keywords
- Prospective Memory Performance, Prospective Memory Outcome, Parkinson's Disease
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 52 participants (actual)
- Lead sponsor
- Washington University School of MedicineUniversity, hospital or other
- Collaborators
- National Institutes of Health (NIH)
- Study start
- 18 Nov 2009 (actual)
- Primary completion
- 27 Aug 2010 (actual)
- Study completion
- 27 Aug 2010 (actual)
- First posted
- 4 Jun 2009 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators tested whether prospective memory is impaired in individuals with Parkinson's Disease compared to controls using reliable and validated experimental measures. Also, the investigators assessed the impact of Parkinson's medication on prospective memory performance in PD to better estimate prospective memory function in PD patients' everyday (chronically treated) life.
Study design
- Observational model
- Case-control
- Time perspective
- Cross-sectional
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| PD Group | – | – |
| Control Group | – | – |
Who may qualify
- Ages
- 40 to 70 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Community Movement Disorder Clinic at Washington University St. Louis
Key inclusion criteria (8 listed)
- PD Group:
- Control Group:
Key exclusion criteria (7 listed)
- PD Group and Control Group:
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Virtual Week
Time frame: One session at baseline.
Prospective Memory Task; Score range is 0-100%, with higher scores being better performance.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 May 2022.
- Results publication: PubMed 23527645Foster ER, Rose NS, McDaniel MA, Rendell PG. Prospective memory in Parkinson disease during a virtual week: effects of both prospective and retrospective demands. Neuropsychology. 2013 Mar;27(2):170-81. doi: 10.1037/a0031946.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Tamara G Hershey, Ph.D. principal investigator
Washington University School of Medicine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Memory and Prospective Memory, run by Washington University School of Medicine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 May 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Virtual Week (time frame: One session at baseline.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT00913640, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 May 2022.