SchizophreniaNCT01312649
Feeling of Being in Control of One's Own Action
A study testing Experimental psychology methods (computer tests) in people with Schizophrenia and Bipolar Disorders, run by University Hospital, Strasbourg, France at 1 site in France.
Trial summary
The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). Read more about this study
- Who is it for?
- Ages 18 to 55 yearsHealthy volunteers can take part
- Conditions the study is for
- Schizophrenia, Bipolar Disorders
- What is being tested?
- Experimental psychology methods (computer tests)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 198 participants
- Where
- 1 siteFrance
- Study dates
- Apr 2011to 4 Jul 2017
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 55 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Patients with schizophrenia or bipolar disorders (criteria DSM IV) or healthy controls matched with patients on age, sex and education level
- 18-55 years old
Who cannot join
- Past history affecting CNS
- Invalidating sensory disorders
- Intake of psychotropic drugs, except for patients
- Intake of benzodiazepines
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Feeling of Being in Control of One's Own Action: Which Mechanisms in Healthy Volunteers and in Mental Diseases
The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). These symptoms are mainly encountered in patients with schizophrenia, and the investigators will distinguish patients with schizophrenia with or without this symptom together with patients with bipolar disorder. Based on the investigators previous studies, this project will help to determine the role of two elementary mechanisms in the ability to feel in control of voluntary actions: (1) the processing of the sensory consequences of action, and (2) the ability to build mental representations for sequenced actions.
- Conditions
- Schizophrenia, Bipolar Disorders
- Being tested
- Experimental psychology methods (computer tests)
- Medical subject headings
- Schizophrenia, Bipolar Disorder
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Experimental psychology methods (computer tests)Behavioural
| Study group | Role | What they receive |
|---|---|---|
| Arm 1 | Experimental | Healthy volunteers Receives: Behavioral: Experimental psychology methods (computer tests) |
| Arm 2 | Experimental | Schizophrenia with history of delusions of control Receives: Behavioral: Experimental psychology methods (computer tests) |
| Arm 3 | Experimental | Schizophrenia without history of delusions of control Receives: Behavioral: Experimental psychology methods (computer tests) |
| Arm 4 | Experimental | Bipolar disorders Receives: Behavioral: Experimental psychology methods (computer tests) |
| Arm 5 | Active comparator | Matched healthy controls Receives: Behavioral: Experimental psychology methods (computer tests) |
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Mar 2011 (estimated)
- Study startApr 2011
- Primary completion15 Jun 2017
- Study completion4 Jul 2017
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for SchizophreniaStudies of the same condition, open and under way.
- More trials run by University Hospital, Strasbourg, FranceThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 198 participants (actual)
Sponsor and investigators
- Lead sponsor
- University Hospital, Strasbourg, France
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Anne GIERSCH, MD, Study director, Hôpitaux Universitaires de Strasbourg
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT01312649
- Sponsor's protocol ID
- 4880
- Status last verified
- Dec 2025
- First submitted
- 1 Mar 2011
- Last updated
- 16 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
Publications
Turgeon M, Giersch A, Delevoye-Turrell Y, Wing AM. Impaired predictive timing with spared time interval production in individual with schizophrenia. Psychiatry Res. 2012 May 15;197(1-2):13-8. doi: 10.1016/j.psychres.2012.03.003. Epub 2012 Apr 11.
PubMed 22497958
Study at a glance
From the registry record, last updated by the sponsor on 16 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Feeling of Being in Control of One's Own Action: Which Mechanisms in Healthy Volunteers and in Mental Diseases
- ClinicalTrials.gov ID
- NCT01312649
- Acronym / sponsor ID
- 4880
- Conditions
- Schizophrenia, Bipolar Disorders
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 198 participants (actual)
- Lead sponsor
- University Hospital, Strasbourg, FranceUniversity, hospital or other
- Study start
- Apr 2011 (actual)
- Primary completion
- 15 Jun 2017 (actual)
- Study completion
- 4 Jul 2017 (actual)
- First posted
- 11 Mar 2011 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The investigators aim is to understand the cognitive mechanisms that contribute to the emergence of delusions of control (the belief that one's own actions or thoughts are controlled by an external force). These symptoms are mainly encountered in patients with schizophrenia, and the investigators will distinguish patients with schizophrenia with or without this symptom together with patients with bipolar disorder. Based on the investigators previous studies, this project will help to determine the role of two elementary mechanisms in the ability to feel in control of voluntary actions: (1) the processing of the sensory consequences of action, and (2) the ability to build mental representations for sequenced actions.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 5
| Arm | Type | Receives |
|---|---|---|
| Arm 1 | Experimental | Behavioral: Experimental psychology methods (computer tests)Healthy volunteers |
| Arm 2 | Experimental | Behavioral: Experimental psychology methods (computer tests)Schizophrenia with history of delusions of control |
| Arm 3 | Experimental | Behavioral: Experimental psychology methods (computer tests)Schizophrenia without history of delusions of control |
| Arm 4 | Experimental | Behavioral: Experimental psychology methods (computer tests)Bipolar disorders |
| Arm 5 | Active comparator | Behavioral: Experimental psychology methods (computer tests)Matched healthy controls |
Who may qualify
- Ages
- 18 to 55 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Patients with schizophrenia or bipolar disorders (criteria DSM IV) or healthy controls matched with patients on age, sex and education level
- 18-55 years old
Key exclusion criteria (4 listed)
- Past history affecting CNS
- Invalidating sensory disorders
- Intake of psychotropic drugs, except for patients
- Intake of benzodiazepines
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Experimental psychology methods (computer tests) | Behavioural | Arm 1, Arm 2, Arm 3, Arm 4, Arm 5 |
Primary outcome
Not reported in the source record.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Dec 2025.
- Results publication: PubMed 22497958Turgeon M, Giersch A, Delevoye-Turrell Y, Wing AM. Impaired predictive timing with spared time interval production in individual with schizophrenia. Psychiatry Res. 2012 May 15;197(1-2):13-8. doi: 10.1016/j.psychres.2012.03.003. Epub 2012 Apr 11.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Anne GIERSCH, MD study director
Hôpitaux Universitaires de Strasbourg
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Experimental psychology methods (computer tests) in people with Schizophrenia and Bipolar Disorders, run by University Hospital, Strasbourg, France at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT01312649, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Dec 2025.