Cardiac ArrestflightsNCT02002481
Comparison of the Quality of CPR by Professional Helpers (Emergency Physicians / Paramedics) During Flights
A study testing transport in people with Cardiac Arrest, run by University Hospital of Cologne at 1 site in Germany.
Trial summary
Investigation of the influence of narrowness and unusual circumstances on the CPR-quality Read more about this study
- Who is it for?
- Ages 18 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Cardiac Arrest
- What is being tested?
- transport
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteGermany
- Study dates
- Dec 2013to Dec 2015
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- emergency physician
- paramedic
- > 18 years
- < 60 years
Who cannot join
- pregnant
- lay rescuers
Trial locations and contacts
1 site in 1 country.
Germany1 site, 1 recruiting
- Recruiting
Uniklinik Köln
Cologne, North Rhine-Westphalia, 50937
Stefan Braunecker, MD, 0221-478-97729, stefan.braunecker@uk-koeln.de
0221-478-97729, jochen.hinkelbein@uk-koeln.de
About this study
Official title: Vergleich Der Qualität Der Kardiopulmonalen Reanimation Durch Professioneller Helfer (Notärzte / Rettungsassistenten) während Lufttransporten
Investigation of the influence of narrowness and unusual circumstances on the CPR-quality
Read the detailed description
Even for paramedics and emergency physicians, the resuscitation of patients with cardiac arrest remains a challenge. Previous studies have shown that the cardiac output varies widely even under normal ambient conditions. Especially the mean frequenices of cardiac compression varies from 60 to 160/min, as well as the now-flow-time. Aim of this study is to investigate how narrowness and movement during a transport affect the CPR-performance.
For this, we examine the impact of the common transport options (air and ground) on the outcome-varity on a manikin. The subjects for this study are professional rescuers (emergency physicians / paramedics) who perform a 10 minute ALS-CPR in either normal circumstances (resuscitation-room) or during transportation.
- Conditions
- Cardiac Arrest
- Being tested
- transport
- Medical subject headings
- Heart Arrest
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
transportOther
The manikin will be resuscitated during a transport in a vessel by a professional team (emergency physician / paramedic).
| Study group | Role | What they receive |
|---|---|---|
| Control | No intervention | 10 minutes ALS-CPR in a normal environment |
| Transport | Experimental | 10 minutes ALS-CPR during a transport Receives: Other: transport |
What is being measured
The primary outcome is the main question the study is designed to answer.
The average achieved cardiac output
The main goal of the study is the average achieved cardiac output. Data acquisition is carried out on a resuscitation-manikin which can measure compression-rate (CR) and compression-depth (CD). The data are recorded by a computer during the CPR. To calculate the cardiac output, we multiply the average CR [1/min] with the average CD [mm] during the 10 min manikin-resuscitation. The thus obtained average cardiac-output (CO = CR x CD), measured in [mm/min], will be compared in each group.
Measured: after 10 minutes
Secondary outcomes (1)
Now-flow-time
Second objective of the study is the time without chest-compression during the 10 minutes ALS-CPR. The now-flow-time is read out of the recorded manikin-data specify, in [min] and [sec]. As a result, the average now-flow-time in each group will be calculated and compared for each group.
Measured: after 10 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Dec 2013 (estimated)
- Study startDec 2013
- Primary completionAug 2015 (estimated)
- Study completionDec 2015 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Cardiac ArrestStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital of Cologne
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Dr. med. Stefan Braunecker, University Hospital of Cologne
- Investigators
- Stefan Braunecker, MD, Principal investigator, University Hospital of CologneJochen Hinkelbein, MD, Principal investigator, University Hospital of CologneJan Hilgers, MD, Principal investigator, University Hospital of Cologne
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02002481
- Sponsor's protocol ID
- 11-289
- Acronym
- flights
- Status last verified
- May 2015
- First submitted
- 29 Nov 2013
- Last updated
- 5 May 2015
- Results posted
- No
- Data monitoring committee
- No
Publications
Schmitz J, Ernst C, Varghese LJK, Kerkhoff S, Jansen G, Hinkelbein J. A two-rescuer-method significantly alters CPR-quality during cardiopulmonary resuscitation in an airliner cabin - a randomized, controlled manikin trial. Sci Rep. 2025 Dec 10;15(1):43585. doi: 10.1038/s41598-025-30996-1.
PubMed 41372341
Study at a glance
From the registry record, last updated by the sponsor on 5 May 2015. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Vergleich Der Qualität Der Kardiopulmonalen Reanimation Durch Professioneller Helfer (Notärzte / Rettungsassistenten) während Lufttransporten
- ClinicalTrials.gov ID
- NCT02002481
- Acronym / sponsor ID
- flights / 11-289
- Conditions
- Cardiac Arrest
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- University Hospital of CologneUniversity, hospital or other
- Study start
- Dec 2013
- Primary completion
- Aug 2015 (estimated)
- Study completion
- Dec 2015 (estimated)
- First posted
- 5 Dec 2013 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Investigation of the influence of narrowness and unusual circumstances on the CPR-quality
Detailed description
Even for paramedics and emergency physicians, the resuscitation of patients with cardiac arrest remains a challenge. Previous studies have shown that the cardiac output varies widely even under normal ambient conditions. Especially the mean frequenices of cardiac compression varies from 60 to 160/min, as well as the now-flow-time. Aim of this study is to investigate how narrowness and movement during a transport affect the CPR-performance.
For this, we examine the impact of the common transport options (air and ground) on the outcome-varity on a manikin. The subjects for this study are professional rescuers (emergency physicians / paramedics) who perform a 10 minute ALS-CPR in either normal circumstances (resuscitation-room) or during transportation.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control | No intervention | –10 minutes ALS-CPR in a normal environment |
| Transport | Experimental | Other: transport10 minutes ALS-CPR during a transport |
Who may qualify
- Ages
- 18 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- emergency physician
- paramedic
- > 18 years
- < 60 years
Key exclusion criteria (2 listed)
- pregnant
- lay rescuers
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| transportThe manikin will be resuscitated during a transport in a vessel by a professional team (emergency physician / paramedic). | Other | Transport |
Primary outcome
The average achieved cardiac output
Time frame: after 10 minutes
The main goal of the study is the average achieved cardiac output. Data acquisition is carried out on a resuscitation-manikin which can measure compression-rate (CR) and compression-depth (CD). The data are recorded by a computer during the CPR. To calculate the cardiac output, we multiply the average CR [1/min] with the average CD [mm] during the 10 min manikin-resuscitation. The thus obtained average cardiac-output (CO = CR x CD), measured in [mm/min], will be compared in each group.
1 secondary outcome
Now-flow-time
Time frame: after 10 minutes
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 May 2015.
- Derived from this study: PubMed 41372341Schmitz J, Ernst C, Varghese LJK, Kerkhoff S, Jansen G, Hinkelbein J. A two-rescuer-method significantly alters CPR-quality during cardiopulmonary resuscitation in an airliner cabin - a randomized, controlled manikin trial. Sci Rep. 2025 Dec 10;15(1):43585. doi: 10.1038/s41598-025-30996-1.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Stefan Braunecker, MD principal investigator
University Hospital of Cologne
Jochen Hinkelbein, MD principal investigator
University Hospital of Cologne
Jan Hilgers, MD principal investigator
University Hospital of Cologne
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing transport in people with Cardiac Arrest, run by University Hospital of Cologne at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 5 May 2015. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Stefan Braunecker, MD (0221-478-97729, stefan.braunecker@uk-koeln.de), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The average achieved cardiac output (time frame: after 10 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02002481, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 May 2015.