Primary Body Region (Arranged Most Common to Least)AEGISNCT02285868
ATI Evidence-based Guide Investigating Clinical Services
An observational study of Primary Body Region (Arranged Most Common to Least) and Lumbar/SI, run by ATI Holdings, LLC at 1 site in United States.
Trial summary
The goal of this study is to evaluate how standard-of-care outpatient rehabilitation is delivered and how variation in care delivery mechanisms relates to clinical outcomes, service utilization, and value in patients receiving physical or occupational therapy. Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee
- How many people
- 4,000,000 participants
- Where
- 1 siteUnited States
- Study dates
- 24 Feb 2026to 24 Feb 2029
- How long will I take part?
- 1 Year
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: All patients presenting ith orthopedic rehabilitation needs
This study involves retrospective secondary analysis of existing standard-of-care documentation from ATI's outpatient rehabilitation EMR. There will be no prospective data collection, no recruitment, and no interaction with patients.
After a patient's episode of care is completed (discharge or last recorded visit), the PI will identify eligible encounters based on prespecified inclusion/exclusion criteria (e.g., outpatient PT/OT services at ATI on or after January 1, 2016.
Trial locations and contacts
1 site in 1 country.
United States1 site
ATI Physical Therapy and Institute for Musculoskeletal Advancement
Downers Grove, Illinois, 60515
About this study
Official title: ATI Evidence-Based Guide Investigating Clinical Services: Rehabilitation and Physical Therapy Patient Outcomes Registry
The goal of this study is to evaluate how standard-of-care outpatient rehabilitation is delivered and how variation in care delivery mechanisms relates to clinical outcomes, service utilization, and value in patients receiving physical or occupational therapy. The study will focus on patients with musculoskeletal (MSK) conditions receiving physical or occupational therapy.
The focus is to use existing standard-of-care documentation in a physical therapy (PT) electronic medical record (EMR) to evaluate patient characteristics, interventions delivered, utilization management, and clinical outcomes in routine outpatient PT care, in order to generate evidence to improve clinical effectiveness and quality of care. Researchers will compare different care delivery mechanisms to see if variations lead to significant differences in outcomes.
Read more
Participants will have their standard-of-care documentation analyzed, including routine clinical measures, objective/functional measures, and patient-reported outcomes. They will not be directly involved in research interventions or randomization. This study does not involve a research intervention, randomization, or alteration of clinical care. It is a retrospective cohort study analyzing existing standard-of-care documentation from ATI's physical therapy EMR.
Data are collected via the investigators proprietary electronic medical record system and are synthetic to the clinical process that is, the data are collected in real-time with patients and the scores are immediately provided to the treating therapist as well as archived for later Registry and scientific use.
Read the detailed description
Musculoskeletal (MSK) conditions are prevalent1 and contribute substantially to healthcare utilization and cost. Physical therapy is a non-surgical, non-pharmacological intervention that can be clinically effective and cost-effective for many MSK presentations, with a large proportion of patients improving without requiring escalation of care. In the context of evolving reimbursement and value-based care pressures, it is increasingly important to understand the clinical effectiveness, utilization patterns, and value implications of PT as delivered in routine outpatient practice. (1-6)
To address these priorities, investigators from ATI and the University of South Carolina are interested in evaluating how standard-of-care outpatient rehabilitation is delivered and how variation in care delivery mechanisms relates to clinical outcomes, service utilization, and value. In this retrospective study, we will conduct secondary analyses of existing standard-of-care documentation within ATI's PT EMR, without altering clinical care or interacting with patients. Care delivery mechanisms of interest include, but are not limited to: (1) delivery mode (in-clinic, telehealth, remote therapeutic moderating (RTM), and hybrid models when documented); (2) use of care extenders (PTAs/Technicians) when identifiable in documentation; (3) specialty service lines and provider qualifications (e.g., Women's Health, Hand Therapy, Vestibular Therapy, Work Comp/Work Hardening, advanced training/certifications); and (4) types of interventions delivered (e.g., exercise therapy, manual therapy, therapeutic modalities), as documented as part of routine care. (7-9)
ATI is a large national outpatient MSK provider delivering physical and occupational therapy services. Investigators have previously used ATI clinical outcomes resources (e.g., the ATI EMR) to characterize care patterns, evaluate outcomes and measurement properties, and explore predictors of utilization behaviors such as canceled visits. The present protocol extends this work by leveraging existing standard-of-care EMR documentation to evaluate patient characteristics, interventions delivered, utilization management patterns, and clinical and objective/functional outcomes in routine outpatient care, producing evidence to inform clinical effectiveness, quality improvement, implementation efforts, and policy-relevant value questions. (4,10-13)
This study is a retrospective cohort study existing standard-of-care documentation from the ATI physical therapy EMR (including routinely collected clinical measures, objective/functional measures, and patient-reported outcomes) for patients receiving physical or occupational therapy beginning January 1, 2016. All interventions referenced in the dataset represent usual care delivered as part of clinical practice and were not assigned for research purposes.
Primary Objective: To use existing standard-of-care documentation in a physical therapy (PT) electronic medical record (EMR) to evaluate patient characteristics, interventions delivered, utilization management, and clinical outcomes in routine outpatient PT care, in order to generate evidence to improve clinical effectiveness and quality of care
Specific Aims Clinical Research (effectiveness in real-world practice)
1)Use retrospective EMR data to evaluate the real-world effectiveness of standard-of-care PT services (including prevention programs, interventions, and educational efforts) for prevalent MSK conditions by examining changes in routinely captured clinical outcomes, objective/functional measures, and patient-reported outcomes over an episode of care.
Heath Policy (Value, cost-efficiency, and care pathways) Use retrospective EMR data to examine PT utilization management and its association with quality, effectiveness, and cost-efficiency across care pathways and practice patterns (e.g., visit authorization patterns, visit frequency, episode duration, time to evaluation, gaps in care, and discharge disposition). When available within the data environment, analyses will also evaluate downstream indicators of value such as opioid utilization, return to function/work/sport, and relationships between outcomes and utilization/cost to inform value-based care and payer-relevant questions.
Implementation and Quality Improvement (Adoption + data quality) Evaluate implementation and sustainability of routine clinical practices by assessing patterns of adoption of assessments/interventions, variation in care delivery, completeness of outcome capture (PROMs/objective tests), patient satisfaction, and resource/service utilization-informing strategies to improve consistent data capture and quality.
Sports Medicine (Athlete lifecycle + RTS decision-making) Among sports/athlete episodes (as identifiable in the EMR), evaluate the effectiveness of sports medicine rehabilitation services across the athlete lifecycle-including risk screening where captured, rehabilitation outcomes, and criteria-based return-to-sport/return-to-function outcomes when documented.
- Conditions
- Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee, Shoulder, Cervical/Thoracic, Foot/Ankle
- Keywords
- Orthopedic rehabilitation, Rehabilitation outcomes, Physical therapy, Physical therapy outcomes, occupational therapy, Standard of care
- Medical subject headings
- Neurologic Manifestations, Fibromyalgia, Headache, Lymphedema
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Arm, Shoulder and Hand injuries | Pre- and post-treatment outcomes of care as measured by the DASH (Disabilities of the Arm, Shoulder and Hand) via physical therapy | |
| Lumbar spine injuries | Pre- and post-treatment outcomes of care as measured by the Modified Oswestry (lumbar spine) via physical therapy | |
| Knee injuries | Pre- and post-treatment outcomes of care as measured by the Knee Outcome Survey via physical therapy | |
| Foot and ankle injuries | Pre- and post-treatment outcomes of care as measured by the Foot \& Ankle Ability Measure via physical therapy | |
| Hip and lower extremity injuries | Pre- and post-treatment outcomes of care as measured by the Lower Extremity Functional Scale via physical therapy | |
| Neck injuries | Pre- and post-treatment outcomes of care as measured by the Neck Disability Index Questionnaire via physical therapy |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in functional status
Measured: 60 days
Secondary outcomes (1)
Change in global health status
Measured: 60 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Nov 2014 (estimated)
- Study start24 Feb 2026
- Primary completion24 Feb 2029 (estimated)
- Study completion24 Feb 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (12)Papers the sponsor has linked to this study.
- Other trials for Primary Body Region (Arranged Most Common to Least)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Other
- Enrolment
- 4,000,000 participants (estimated)
- Target duration
- 1 Year
Sponsor and investigators
- Lead sponsor
- ATI Holdings, LLC
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Principal investigator, Natalie Myers, ATI Holdings, LLC
- Investigators
- Natalie Myers, PhD, ATC, Principal investigator, ATI Physical Therapy and Institute for Musculoskeletal Advancement
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02285868
- Sponsor's protocol ID
- ATI EGIS01012015
- Acronym
- AEGIS
- Status last verified
- Mar 2026
- First submitted
- 4 Nov 2014
- Last updated
- 5 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Denninger TR, Cook CE, Chapman CG, McHenry T, Thigpen CA. The Influence of Patient Choice of First Provider on Costs and Outcomes: Analysis From a Physical Therapy Patient Registry. J Orthop Sports Phys Ther. 2018 Feb;48(2):63-71. doi: 10.2519/jospt.2018.7423. Epub 2017 Oct 26.
PubMed 29073842Lutz AD, Brooks JM, Chapman CG, Shanley E, Stout CE, Thigpen CA. Risk Adjustment of the Modified Low Back Pain Disability Questionnaire and Neck Disability Index to Benchmark Physical Therapist Performance: Analysis From an Outcomes Registry. Phys Ther. 2020 Apr 17;100(4):609-620. doi: 10.1093/ptj/pzaa019.
PubMed 32285130Lutz AD, Rodriguez S, DeBuck KF, Denninger TR, Myers LM, Myers NL. Work Conditioning: The Appropriate Stepped Physical Therapy Care for Injured Workers in Physically Demanding Roles: A Retrospective Cohort Study. J Occup Environ Med. 2026 May 1;68(5):385-390. doi: 10.1097/JOM.0000000000003611. Epub 2025 Nov 11.
PubMed 41214483Lutz AD, Windsor BA, Shanley E, Denninger TR, Harrington SE, Thigpen CA. A comparison of treatment signatures of high and low performing physical therapists for patients with lower back pain: analysis of spine care from a physical therapy outcomes registry. Spine J. 2022 May;22(5):847-856. doi: 10.1016/j.spinee.2021.11.008. Epub 2021 Nov 20.
PubMed 34813956Hawley-Hague H, Lasrado R, Martinez E, Stanmore E, Tyson S. A scoping review of the feasibility, acceptability, and effects of physiotherapy delivered remotely. Disabil Rehabil. 2023 Nov;45(23):3961-3977. doi: 10.1080/09638288.2022.2138574. Epub 2022 Nov 2.
PubMed 36325612Domingues B, Pereira AP, Pradhan A, Zidde C, Janela D, Marramaque C, Bento V, Yanamadala V, Cohen SP, Belz L, Wang K, Correia FD, Costa F. Digital Versus In-Person Physical Therapy in Adults With Musculoskeletal Conditions: Retrospective Matched-Cohort Analysis of Surgery and Low-Value Surgical Rates. J Med Internet Res. 2025 Dec 17;27:e82573. doi: 10.2196/82573.
PubMed 41288021Hinman RS, Campbell PK, Kimp AJ, Russell T, Foster NE, Kasza J, Harris A, Bennell KL. Telerehabilitation consultations with a physiotherapist for chronic knee pain versus in-person consultations in Australia: the PEAK non-inferiority randomised controlled trial. Lancet. 2024 Mar 30;403(10433):1267-1278. doi: 10.1016/S0140-6736(23)02630-2. Epub 2024 Mar 7.
PubMed 38461844Demont A, Bourmaud A, Kechichian A, Desmeules F. The impact of direct access physiotherapy compared to primary care physician led usual care for patients with musculoskeletal disorders: a systematic review of the literature. Disabil Rehabil. 2021 Jun;43(12):1637-1648. doi: 10.1080/09638288.2019.1674388. Epub 2019 Oct 11.
PubMed 31603709Burge E, Monnin D, Berchtold A, Allet L. Cost-Effectiveness of Physical Therapy Only and of Usual Care for Various Health Conditions: Systematic Review. Phys Ther. 2016 Jun;96(6):774-86. doi: 10.2522/ptj.20140333. Epub 2015 Dec 17.
PubMed 26678447Lentz TA, Ikeaba U, Alhanti B, Lutz A, George SZ, Cook C, Thigpen C. Self-reported disability trajectories and their predictors among patients receiving care by physical therapists for musculoskeletal conditions: a retrospective analysis of registry data. BMJ Open. 2025 Jun 20;15(6):e099315. doi: 10.1136/bmjopen-2025-099315.
PubMed 40541444Dieleman JL, Cao J, Chapin A, Chen C, Li Z, Liu A, Horst C, Kaldjian A, Matyasz T, Scott KW, Bui AL, Campbell M, Duber HC, Dunn AC, Flaxman AD, Fitzmaurice C, Naghavi M, Sadat N, Shieh P, Squires E, Yeung K, Murray CJL. US Health Care Spending by Payer and Health Condition, 1996-2016. JAMA. 2020 Mar 3;323(9):863-884. doi: 10.1001/jama.2020.0734.
PubMed 32125402McConaghy K, Klika AK, Apte SS, Erdemir A, Derwin K, Piuzzi NS. A Call to Action for Musculoskeletal Research Funding: The Growing Economic and Disease Burden of Musculoskeletal Conditions in the United States Is Not Reflected in Musculoskeletal Research Funding. J Bone Joint Surg Am. 2023 Mar 15;105(6):492-498. doi: 10.2106/JBJS.22.00693. Epub 2022 Nov 9.
PubMed 36574617
Study at a glance
From the registry record, last updated by the sponsor on 5 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- ATI Evidence-Based Guide Investigating Clinical Services: Rehabilitation and Physical Therapy Patient Outcomes Registry
- ClinicalTrials.gov ID
- NCT02285868
- Acronym / sponsor ID
- AEGIS / ATI EGIS01012015
- Conditions
- Primary Body Region (Arranged Most Common to Least), Lumbar/SI, Knee, Shoulder, Cervical/Thoracic, Foot/Ankle
- Keywords
- Orthopedic rehabilitation, Rehabilitation outcomes, Physical therapy, Physical therapy outcomes, occupational therapy, Standard of care
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 4,000,000 participants (estimated)
- Lead sponsor
- ATI Holdings, LLCIndustry (pharma, biotech, devices)
- Study start
- 24 Feb 2026 (actual)
- Primary completion
- 24 Feb 2029 (estimated)
- Study completion
- 24 Feb 2029 (estimated)
- First posted
- 7 Nov 2014 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this study is to evaluate how standard-of-care outpatient rehabilitation is delivered and how variation in care delivery mechanisms relates to clinical outcomes, service utilization, and value in patients receiving physical or occupational therapy. The study will focus on patients with musculoskeletal (MSK) conditions receiving physical or occupational therapy.
The focus is to use existing standard-of-care documentation in a physical therapy (PT) electronic medical record (EMR) to evaluate patient characteristics, interventions delivered, utilization management, and clinical outcomes in routine outpatient PT care, in order to generate evidence to improve clinical effectiveness and quality of care. Researchers will compare different care delivery mechanisms to see if variations lead to significant differences in outcomes.
Participants will have their standard-of-care documentation analyzed, including routine clinical measures, objective/functional measures, and patient-reported outcomes. They will not be directly involved in research interventions or randomization. This study does not involve a research intervention, randomization, or alteration of clinical care. It is a retrospective cohort study analyzing existing standard-of-care documentation from ATI's physical therapy EMR.
Data are collected via the investigators proprietary electronic medical record system and are synthetic to the clinical process that is, the data are collected in real-time with patients and the scores are immediately provided to the treating therapist as well as archived for later Registry and scientific use.
Detailed description
Musculoskeletal (MSK) conditions are prevalent1 and contribute substantially to healthcare utilization and cost. Physical therapy is a non-surgical, non-pharmacological intervention that can be clinically effective and cost-effective for many MSK presentations, with a large proportion of patients improving without requiring escalation of care. In the context of evolving reimbursement and value-based care pressures, it is increasingly important to understand the clinical effectiveness, utilization patterns, and value implications of PT as delivered in routine outpatient practice. (1-6)
To address these priorities, investigators from ATI and the University of South Carolina are interested in evaluating how standard-of-care outpatient rehabilitation is delivered and how variation in care delivery mechanisms relates to clinical outcomes, service utilization, and value. In this retrospective study, we will conduct secondary analyses of existing standard-of-care documentation within ATI's PT EMR, without altering clinical care or interacting with patients. Care delivery mechanisms of interest include, but are not limited to: (1) delivery mode (in-clinic, telehealth, remote therapeutic moderating (RTM), and hybrid models when documented); (2) use of care extenders (PTAs/Technicians) when identifiable in documentation; (3) specialty service lines and provider qualifications (e.g., Women's Health, Hand Therapy, Vestibular Therapy, Work Comp/Work Hardening, advanced training/certifications); and (4) types of interventions delivered (e.g., exercise therapy, manual therapy, therapeutic modalities), as documented as part of routine care. (7-9)
ATI is a large national outpatient MSK provider delivering physical and occupational therapy services. Investigators have previously used ATI clinical outcomes resources (e.g., the ATI EMR) to characterize care patterns, evaluate outcomes and measurement properties, and explore predictors of utilization behaviors such as canceled visits. The present protocol extends this work by leveraging existing standard-of-care EMR documentation to evaluate patient characteristics, interventions delivered, utilization management patterns, and clinical and objective/functional outcomes in routine outpatient care, producing evidence to inform clinical effectiveness, quality improvement, implementation efforts, and policy-relevant value questions. (4,10-13)
This study is a retrospective cohort study existing standard-of-care documentation from the ATI physical therapy EMR (including routinely collected clinical measures, objective/functional measures, and patient-reported outcomes) for patients receiving physical or occupational therapy beginning January 1, 2016. All interventions referenced in the dataset represent usual care delivered as part of clinical practice and were not assigned for research purposes.
Primary Objective: To use existing standard-of-care documentation in a physical therapy (PT) electronic medical record (EMR) to evaluate patient characteristics, interventions delivered, utilization management, and clinical outcomes in routine outpatient PT care, in order to generate evidence to improve clinical effectiveness and quality of care
Specific Aims Clinical Research (effectiveness in real-world practice)
1)Use retrospective EMR data to evaluate the real-world effectiveness of standard-of-care PT services (including prevention programs, interventions, and educational efforts) for prevalent MSK conditions by examining changes in routinely captured clinical outcomes, objective/functional measures, and patient-reported outcomes over an episode of care.
Heath Policy (Value, cost-efficiency, and care pathways) Use retrospective EMR data to examine PT utilization management and its association with quality, effectiveness, and cost-efficiency across care pathways and practice patterns (e.g., visit authorization patterns, visit frequency, episode duration, time to evaluation, gaps in care, and discharge disposition). When available within the data environment, analyses will also evaluate downstream indicators of value such as opioid utilization, return to function/work/sport, and relationships between outcomes and utilization/cost to inform value-based care and payer-relevant questions.
Implementation and Quality Improvement (Adoption + data quality) Evaluate implementation and sustainability of routine clinical practices by assessing patterns of adoption of assessments/interventions, variation in care delivery, completeness of outcome capture (PROMs/objective tests), patient satisfaction, and resource/service utilization-informing strategies to improve consistent data capture and quality.
Sports Medicine (Athlete lifecycle + RTS decision-making) Among sports/athlete episodes (as identifiable in the EMR), evaluate the effectiveness of sports medicine rehabilitation services across the athlete lifecycle-including risk screening where captured, rehabilitation outcomes, and criteria-based return-to-sport/return-to-function outcomes when documented.
Study design
- Observational model
- Other
- Time perspective
- Other
- Target follow-up
- 1 Year
- Number of arms
- 6
| Arm | Type | Receives |
|---|---|---|
| Arm, Shoulder and Hand injuries | – | –Pre- and post-treatment outcomes of care as measured by the DASH (Disabilities of the Arm, Shoulder and Hand) via physical therapy |
| Lumbar spine injuries | – | –Pre- and post-treatment outcomes of care as measured by the Modified Oswestry (lumbar spine) via physical therapy |
| Knee injuries | – | –Pre- and post-treatment outcomes of care as measured by the Knee Outcome Survey via physical therapy |
| Foot and ankle injuries | – | –Pre- and post-treatment outcomes of care as measured by the Foot \& Ankle Ability Measure via physical therapy |
| Hip and lower extremity injuries | – | –Pre- and post-treatment outcomes of care as measured by the Lower Extremity Functional Scale via physical therapy |
| Neck injuries | – | –Pre- and post-treatment outcomes of care as measured by the Neck Disability Index Questionnaire via physical therapy |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- All patients presenting ith orthopedic rehabilitation needs
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Change in functional status
Time frame: 60 days
1 secondary outcome
Change in global health status
Time frame: 60 days
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Mar 2026.
- Background: PubMed 29073842Denninger TR, Cook CE, Chapman CG, McHenry T, Thigpen CA. The Influence of Patient Choice of First Provider on Costs and Outcomes: Analysis From a Physical Therapy Patient Registry. J Orthop Sports Phys Ther. 2018 Feb;48(2):63-71. doi: 10.2519/jospt.2018.7423. Epub 2017 Oct 26.
- Background: PubMed 32285130Lutz AD, Brooks JM, Chapman CG, Shanley E, Stout CE, Thigpen CA. Risk Adjustment of the Modified Low Back Pain Disability Questionnaire and Neck Disability Index to Benchmark Physical Therapist Performance: Analysis From an Outcomes Registry. Phys Ther. 2020 Apr 17;100(4):609-620. doi: 10.1093/ptj/pzaa019.
- Background: PubMed 41214483Lutz AD, Rodriguez S, DeBuck KF, Denninger TR, Myers LM, Myers NL. Work Conditioning: The Appropriate Stepped Physical Therapy Care for Injured Workers in Physically Demanding Roles: A Retrospective Cohort Study. J Occup Environ Med. 2026 May 1;68(5):385-390. doi: 10.1097/JOM.0000000000003611. Epub 2025 Nov 11.
- Background: PubMed 34813956Lutz AD, Windsor BA, Shanley E, Denninger TR, Harrington SE, Thigpen CA. A comparison of treatment signatures of high and low performing physical therapists for patients with lower back pain: analysis of spine care from a physical therapy outcomes registry. Spine J. 2022 May;22(5):847-856. doi: 10.1016/j.spinee.2021.11.008. Epub 2021 Nov 20.
- Background: PubMed 36325612Hawley-Hague H, Lasrado R, Martinez E, Stanmore E, Tyson S. A scoping review of the feasibility, acceptability, and effects of physiotherapy delivered remotely. Disabil Rehabil. 2023 Nov;45(23):3961-3977. doi: 10.1080/09638288.2022.2138574. Epub 2022 Nov 2.
- Background: PubMed 41288021Domingues B, Pereira AP, Pradhan A, Zidde C, Janela D, Marramaque C, Bento V, Yanamadala V, Cohen SP, Belz L, Wang K, Correia FD, Costa F. Digital Versus In-Person Physical Therapy in Adults With Musculoskeletal Conditions: Retrospective Matched-Cohort Analysis of Surgery and Low-Value Surgical Rates. J Med Internet Res. 2025 Dec 17;27:e82573. doi: 10.2196/82573.
- Background: PubMed 38461844Hinman RS, Campbell PK, Kimp AJ, Russell T, Foster NE, Kasza J, Harris A, Bennell KL. Telerehabilitation consultations with a physiotherapist for chronic knee pain versus in-person consultations in Australia: the PEAK non-inferiority randomised controlled trial. Lancet. 2024 Mar 30;403(10433):1267-1278. doi: 10.1016/S0140-6736(23)02630-2. Epub 2024 Mar 7.
- Background: PubMed 31603709Demont A, Bourmaud A, Kechichian A, Desmeules F. The impact of direct access physiotherapy compared to primary care physician led usual care for patients with musculoskeletal disorders: a systematic review of the literature. Disabil Rehabil. 2021 Jun;43(12):1637-1648. doi: 10.1080/09638288.2019.1674388. Epub 2019 Oct 11.
- Background: PubMed 26678447Burge E, Monnin D, Berchtold A, Allet L. Cost-Effectiveness of Physical Therapy Only and of Usual Care for Various Health Conditions: Systematic Review. Phys Ther. 2016 Jun;96(6):774-86. doi: 10.2522/ptj.20140333. Epub 2015 Dec 17.
- Background: PubMed 40541444Lentz TA, Ikeaba U, Alhanti B, Lutz A, George SZ, Cook C, Thigpen C. Self-reported disability trajectories and their predictors among patients receiving care by physical therapists for musculoskeletal conditions: a retrospective analysis of registry data. BMJ Open. 2025 Jun 20;15(6):e099315. doi: 10.1136/bmjopen-2025-099315.
- Background: PubMed 32125402Dieleman JL, Cao J, Chapin A, Chen C, Li Z, Liu A, Horst C, Kaldjian A, Matyasz T, Scott KW, Bui AL, Campbell M, Duber HC, Dunn AC, Flaxman AD, Fitzmaurice C, Naghavi M, Sadat N, Shieh P, Squires E, Yeung K, Murray CJL. US Health Care Spending by Payer and Health Condition, 1996-2016. JAMA. 2020 Mar 3;323(9):863-884. doi: 10.1001/jama.2020.0734.
- Background: PubMed 36574617McConaghy K, Klika AK, Apte SS, Erdemir A, Derwin K, Piuzzi NS. A Call to Action for Musculoskeletal Research Funding: The Growing Economic and Disease Burden of Musculoskeletal Conditions in the United States Is Not Reflected in Musculoskeletal Research Funding. J Bone Joint Surg Am. 2023 Mar 15;105(6):492-498. doi: 10.2106/JBJS.22.00693. Epub 2022 Nov 9.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Natalie Myers, PhD, ATC principal investigator
ATI Physical Therapy and Institute for Musculoskeletal Advancement
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Primary Body Region (Arranged Most Common to Least) and Lumbar/SI, run by ATI Holdings, LLC at 1 site in United States.
The full registered description is in the About this study section and the official record.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 5 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in functional status (time frame: 60 days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02285868, which also lists 12 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2026.