Clinical trials: Foot/Ankle
Hemophilia, Arthropathy of Knee
Evaluation of Static Postural Balance in Children With Hemophilia and Its Relationship With Joint Health
Hemophilia is a rare hematological disorder characterized by a partial or complete deficiency of clotting factor VIII or IX.Bleeding disorders mainly affect the musculoskeletal system.
- Conditions
- Hemophilia, Arthropathy of Knee, Arthropathy of Ankle or Foot
- Trial name
- NCT04406519
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Necmettin Erbakan University
Calcaneal Fractures
Sustentaculum Tali Screw Fixation Mode and Postoperative Foot-Ankle Function in Calcaneal Fractures
This is an observational, ambidirectional cohort study. Calcaneal fractures are the most common tarsal bone fractures, and most are intra-articular fractures involving the subtalar joint.
- Trial name
- NCT07822698
- Testing
- Screw Tip Position Relative to the Sustentaculum Tali
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Peking University Third Hospital
Chronic Ankle Instability, Lateral Ankle Sprain
Biomechanics and Intrinsic Foot Muscle Roles in Subjects With Chronic Ankle Instability
The current study involves a prospective interventional study that primarily intends to compare foot joint loadings of participants with chronic ankle instability (CAI) with those of subjects who recovered after an ankle sprain…
- Trial name
- NCT05815576
- Testing
- Intrinsic foot muscle fatigue
- Where
- Belgium
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Foot and Ankle Procedures
Efficacy of Popliteal Nerve Blocks With and Without Dexamethasone on the Duration of Analgesia for Foot & Ankle Surgery
The purpose of this research study to evaluate the effects of dexamethasone as an addition to peripheral nerve block (Put the nerve to sleep with Bupivacaine a numbing medication) on length of pain relief (analgesia)…
- Trial name
- NCT01975285
- Testing
- Dexamethasone, Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long term effectiveness and safety of AUGMENT® Bone Graft vs. autologous bone graft.
- Trial name
- NCT02879149
- Testing
- AUGMENT® Bone Graft, Standard of Care
- Where
- 26 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- BioMimetic Therapeutics
Walking Aided by a Leg Brace in Stroke Subjects
Comparison of the Functional Walking Outcomes of Two Settings of a Commercially Available AFO in Adult Stroke Patients
The purpose of this study is to evaluate how two different settings of a commercially available ankle foot brace affect how stroke patients walk.
- Trial name
- NCT02122783
- Testing
- ADR™ brace resistance, Conventional brace resistance (using hard stops)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Albert Einstein Healthcare Network
Pareses, Lower Extremity
Clinical Trial Comparing C-Brace to Knee Ankle Foot Orthosis (KAFO)/Stance Control Orthosis (SCO)
Prospective, international, multi-center, open-labeled, randomized, controlled cross-over trial to evaluate effectiveness and benefits in patients with lower limb impairment in activities of daily living comparing the C-Brace…
- Trial name
- NCT03906656
- Testing
- C-Brace, KAFO/SCO
- Where
- 13 sites in United States, Austria and 2 more
- Volunteers
- 149 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Foot Diseases, Ankle Disorders Injuries
Baropodometric Assessment of the Podiatric Profile of Nursing Students in Clinical Settings
The nursing profession is highly affected by exhausting positions, namely prolonged standing and walking, which are the second work-related factor hindering foot health.
- Trial name
- NCT05197166
- Testing
- Acute Clinical Settings
- Where
- Portugal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Enfermagem de Coimbra
Pain, Ankle Injuries
Erector Spinae Plane Block and Ankle and Foot Surgery
Regional anesthesia is commonly used in orthopedic and surgical procedures in ankle and foot surgery to manage pain. The ultrasound-guided nerve block is a safe and effective regional anesthesia technique that provides effective…
- Trial name
- NCT05708742
- Testing
- Ultrasound, Bupivacaine Hydrochloride, saline solution
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Cerebral Palsy
Safety and Performance of Agilik in CP
The purpose of this post market study is to demonstrate the safety and performance of a powered extension assist (EA) knee ankle foot orthosis (KAFO), or EA-KAFO, in individuals with knee extension deficiency due to cerebral…
- Trial name
- Agilik (NCT05746871)
- Testing
- Agilik, standard care
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- IRCCS Eugenio Medea
Rotator Cuff Tears, Shoulder Injuries
Randomized Study of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery
Postoperative pain remains undertreated with inadequate analgesic options. Opioids have well-known limitations for both individuals and society; single-injection and continuous peripheral nerve blocks provide intense analgesia…
- Conditions
- Rotator Cuff Tears, Shoulder Injuries, Hallux Valgus, Ankle Arthropathy
- Trial name
- NCT07052721
- Testing
- Experimental Treatment
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of California, San Diego
Ankle Disease, Ankle Injuries
Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery
Effect of Perineural Dexamethasone on the duration of popliteal nerve block for Anesthesia After Pediatric ankle/foot surgery.
- Conditions
- Ankle Disease, Ankle Injuries, Foot Injury, Foot Diseases
- Trial name
- NCT06086418
- Testing
- 0.9 % Sodium Chloride, 0.1mg/kg Dexamethasone, 0.05mg/kg Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Diabetic Neuropathy, Painful
The Effect of Foot and Ankle Exercise on Pain and Quality of Life in Patients With Diabetic Neuropathy
The study will be carried out to determine the effect on pain and quality of life between the groups that received and did not receive foot and ankle exercise training.
- Trial name
- NCT05670600
- Testing
- foot and ankle exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gazi University
Range of Motion, Running
Effect of Whole-body Vibration on the Ankle Joint, Plantar Pressure, and Running Paramethers
The main purpose of this study was the assessment of whole-body vibration warm-up, modified drop jumps, and combination of both on the range of motion of dorsiflexion in the ankle joint and running time.
- Conditions
- Range of Motion, Running, Gait
- Trial name
- NCT06227312
- Testing
- LADY 1 Pro, New Life Balance, exercises
- Where
- Poland
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Balance, Proprioception
Foot Positions Affect Basketball Players With Flatfoot
This study investigated the effect of various initial foot positions on knee and ankle proprioception, balance, dynamic balance, vertical jump, and electromyographical muscle activity in basketball players with FF.
- Conditions
- Balance, Proprioception, Jumping Performance, EMG
- Trial name
- NCT06948812
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Beni-Suef University
Foot Deformity, Hallux Deformity
The Turkish Version of the AOFAS Hallux MTP-IP
The American Orthopedic Foot and Ankle Society hallux metatarsophalangeal-interphalangeal joint scale (AOFAS Hallux MTP-IP) is originally developed in English to evaluate the pain, function and alignment in patients with hallux…
- Conditions
- Foot Deformity, Hallux Deformity, Assessment, Self, Orthopedic Disorder
- Trial name
- NCT05258695
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University - Cerrahpasa
Haemophilia, Arthropathy
Biomechanical Determinants and Patterns Associated to the Pathophysiological Cascade of Ankle Arthropathy in Children With Haemophilia: Non-invasive In-vivo Measurement of Foot Joints in Children With Haemophilia During Gait.
Haemophilia is a rare X chromosome-linked coagulation disorder resulting from a congenital deficiency or absence of circulating factor VIII (Haemophilia A) or factor IX (Haemophilia B).As a consequence, patients with haemophilia…
- Trial name
- 3DMKFM (NCT02229331)
- Testing
- Gait analysis
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Ankle Trauma, Education
Mnemonic for the Ottawa Ankle Rule
The purpose of this study is to evaluate wether the use of a mnemonic strategy could improve the recall of the Ottawa Ankle and foot Rules' guidelines among medical students and residents
- Trial name
- NCT00652353
- Testing
- 44-55-66-PM, control
- Where
- Canada
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Foot Surgery, Ankle Surgery
Liposomal Bupivacaine With Dexamethasone for Foot Surgery
This study aims to understand the ideal formulation to utilize in saphenous nerve and popliteal nerve blocks for foot and ankle procedures.
- Conditions
- Foot Surgery, Ankle Surgery, Post Operative Pain, Popliteal Nerve Block
- Trial name
- NCT06465992
- Testing
- Exparel 266 MG Per 20 ML Injection, Bupivacaine Hcl 0.75% Inj, Dexamethasone
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Total Hip Arthroplasty (THA)
Effects of Foot Core Exercises in Patients With Total Hip Arthroplasty
The goal of this clinical trial is to investigate the effects of foot core exercises on lower extremity muscle strength, viscoelastic properties, functional parameters, foot and ankle posture, balance, and the morphological…
- Trial name
- NCT07665801
- Testing
- Hip Rehabilitation Exercise Program, Foot-Core Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University