Colorectal Postoperative ComplicationCRP-TrackNCT02395380
Evaluation of the Predictive Nature of the Postoperative CRP on Postoperative Recovery in Patients Undergoing Colorectal Resection (CRP-Track)
A study testing C-reactive protein dosage in people with Colorectal Postoperative Complication, run by Centre Hospitalier Departemental Vendee at 2 sites in France.
Trial summary
Colic and rectal resection represents a majority of hospitalizations in visceral surgery. The objective of this study was to evaluate the prognostic of inflammatory markers dosage (CRP, procalcitonin and venous lactate) on the postoperative recovery after colorectal surgery and on the length of stay. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Colorectal Postoperative Complication
- What is being tested?
- C-reactive protein dosage
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 174 participants
- Where
- 2 sitesFrance
- Study dates
- 6 Jul 2015to 13 Jun 2017
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Upper age to 18 years
- Planned hospital stay for a colonic resection with anastomosis without permanent or temporary digestive bypass
- Patient with pre-operative CRP lower or egal to 172 mg/L
- No opposition at the participation of the study
- Expected patient return home after surgery (or convalescent home or not medicalized institution)
Who cannot join
- Patient under guardianship
- Protected or private patient freedom
- Minor patient
- Colectomy surgery with digestive bypass or digestive anastomosis
- Complex combined surgery (significantly intestinal resection associated, another surgical procedure that can interfere with postoperative CRP)
- General inflammatory disease susceptive to modify dosage values
- Anti-inflammatory therapy (AINS/ corticosteroids/ immunosuppressive)
- Patient unable to understand the study
Trial locations and contacts
2 sites in 1 country.
France2 sites
Centre Hospitalier Departemental Vendee
La Roche-sur-Yon, 85925
CHU Nantes
Nantes, 44000
About this study
Official title: Evaluation of the Predictive Nature of the Postoperative CRP on Postoperative Recovery in Patients Undergoing Colorectal Resection
Colic and rectal resection represents a majority of hospitalizations in visceral surgery. The objective of this study was to evaluate the prognostic of inflammatory markers dosage (CRP, procalcitonin and venous lactate) on the postoperative recovery after colorectal surgery and on the length of stay.
- Conditions
- Colorectal Postoperative Complication
- Being tested
- C-reactive protein dosage
- Keywords
- CRP, Postoperative complication, Length of stay
- Medical subject headings
- Postoperative Complications
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
C-reactive protein dosageOther
| Study group | Role | What they receive |
|---|---|---|
| C-reactive protein dosage | Experimental | Not described Receives: Other: C-reactive protein dosage |
What is being measured
The primary outcome is the main question the study is designed to answer.
C-reactive Protein Rate
Comparison C-reactive protein levels < 172 mg/l at 3 post operative day with composite endpoint postoperative recovery (fever, absence of pain >2, intestinal gas transit and patient autonomy for mobility and body care) at 5 post operative day. The Specificity, Sensitivity, PPV, NPV of C-Reactive Protein Levels at Day 3 Post-operative in Determining Day 5 Post-operative Recovery
Measured: 5 postoperative days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Mar 2015 (estimated)
- Study start6 Jul 2015
- Primary completion11 Mar 2017
- Study completion13 Jun 2017
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Colorectal Postoperative ComplicationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 174 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Departemental Vendee
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Emeric ABET, Study director, Centre Hospitalier Departemental Vendee
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02395380
- Sponsor's protocol ID
- CHD 065-14
- Acronym
- CRP-Track
- Status last verified
- Apr 2026
- First submitted
- 2 Mar 2015
- Last updated
- 20 Apr 2026
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- Yes
Publications
Abet E, Drissi F, Couette C, Jean MH, Denimal F, Podevin J, Duchalais E, Meurette G. Predictive value of inflammatory markers for postoperative recovery following colorectal surgery. Int J Colorectal Dis. 2020 Jun;35(6):1125-1131. doi: 10.1007/s00384-020-03594-y. Epub 2020 Apr 14.
PubMed 32291509
Study at a glance
From the registry record, last updated by the sponsor on 20 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of the Predictive Nature of the Postoperative CRP on Postoperative Recovery in Patients Undergoing Colorectal Resection
- ClinicalTrials.gov ID
- NCT02395380
- Acronym / sponsor ID
- CRP-Track / CHD 065-14
- Conditions
- Colorectal Postoperative Complication
- Keywords
- CRP, Postoperative complication, Length of stay
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 174 participants (actual)
- Lead sponsor
- Centre Hospitalier Departemental VendeeUniversity, hospital or other
- Study start
- 6 Jul 2015 (actual)
- Primary completion
- 11 Mar 2017 (actual)
- Study completion
- 13 Jun 2017 (actual)
- First posted
- 23 Mar 2015 (estimated)
- Results
- Posted 20 Apr 2026
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Colic and rectal resection represents a majority of hospitalizations in visceral surgery. The objective of this study was to evaluate the prognostic of inflammatory markers dosage (CRP, procalcitonin and venous lactate) on the postoperative recovery after colorectal surgery and on the length of stay.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| C-reactive protein dosage | Experimental | Other: C-reactive protein dosage |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Upper age to 18 years
- Planned hospital stay for a colonic resection with anastomosis without permanent or temporary digestive bypass
- Patient with pre-operative CRP lower or egal to 172 mg/L
- No opposition at the participation of the study
- Expected patient return home after surgery (or convalescent home or not medicalized institution)
Key exclusion criteria (8 listed)
- Patient under guardianship
- Protected or private patient freedom
- Minor patient
- Colectomy surgery with digestive bypass or digestive anastomosis
- Complex combined surgery (significantly intestinal resection associated, another surgical procedure that can interfere with postoperative CRP)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| C-reactive protein dosage | Other | C-reactive protein dosage |
Primary outcome
C-reactive Protein Rate
Time frame: 5 postoperative days
Comparison C-reactive protein levels < 172 mg/l at 3 post operative day with composite endpoint postoperative recovery (fever, absence of pain >2, intestinal gas transit and patient autonomy for mobility and body care) at 5 post operative day. The Specificity, Sensitivity, PPV, NPV of C-Reactive Protein Levels at Day 3 Post-operative in Determining Day 5 Post-operative Recovery
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Apr 2026.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Results publication: PubMed 32291509Abet E, Drissi F, Couette C, Jean MH, Denimal F, Podevin J, Duchalais E, Meurette G. Predictive value of inflammatory markers for postoperative recovery following colorectal surgery. Int J Colorectal Dis. 2020 Jun;35(6):1125-1131. doi: 10.1007/s00384-020-03594-y. Epub 2020 Apr 14.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Emeric ABET study director
Centre Hospitalier Departemental Vendee
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing C-reactive protein dosage in people with Colorectal Postoperative Complication, run by Centre Hospitalier Departemental Vendee at 2 sites in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 20 Apr 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
C-reactive Protein Rate (time frame: 5 postoperative days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02395380, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Apr 2026.