AzTrials
AzTrials

Drug-Induced Liver InjuryDILI-RNCT02407964

A Retrospective Study on Drug Induced Liver Injury in China

An observational study of Drug-Induced Liver Injury, run by Drug Induced Liver Disease Study Group at 371 sites in China.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
Search all trials

Trial summary

This is a multi-center, open-enrollment, retrospective, non-interventional epidemiologic study without any clinical treatment. Its primary objective is to understand 1) incidence of drug-induced liver injury, including incidences among all the hospitalized patient, among patients in department of hepatic diseases… Read more about this study

Who is it for?
Any age
Conditions the study is for
Drug-Induced Liver Injury
How many people
15,000 participants
Where
371 sitesChina
Study dates
Mar 2015to Jul 2016
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages Any age
  • All sexes
  • No healthy volunteers
  • Child, Adult, Older adult

Study population: Patients who were hospitalized during 2012 to 2014.

Who may be able to join

  • Any hospitalized patients who were diagnosed as drug-induced liver injury, drug-induced liver disease, drug-induced hepatitis, drug-induced hepatocirrhosis, drug-induced hepatic failure, or any other similar diagnosis of drug-induced liver injury nature.
  • The drug-induced liver injury and similar diagnosis were not excluded the possibility of drug-induced nature.

Who cannot join

  • Confirmed non-drug induced liver injury.
  • Insufficient clinical data supporting the diagnosis of drug-induced liver injury.
  • Liver injury resulted from poisons and chemicals.

Trial locations and contacts

371 sites in 1 country.

300 sites in 1 country

China300 sites

  • Department of gastroentrology of Ankang city central hospital

    Ankang

  • Department of gastroenterology of Anqing municipal hospital

    Anqing

  • Department of infectious disease of Anqing municipal hospital

    Anqing

  • Department of tuberculosis of Baoding infectious disease hospital

    Baoding

  • Department of gastroentrology,the third hospital of PLA

    Baoji

  • Department of infectious disease of Baoji No.2 people's hospital

    Baoji

  • Department of infectious disease,the third hospital of PLA

    Baoji

  • Department of tuberculosis,the third hospital of PLA

    Baoji

  • Department of lymph&breast of Baotou tumor hospital

    Baotou

  • Department of breast disease,Tongzhou matermal&child health hospital of Beijing

    Beijing

  • Department of gastroenterology of Beijing Huairou hospital

    Beijing

  • Department of Hepatology of Beijing Ditan Hospital Capital Medical University

    Beijing

  • Department of hepatology of Peking university people's hospital

    Beijing

  • Department of infection of Peking university first hospital

    Beijing

  • Non infedtious liver disease diagnosis and treatment center,302 military hospital of China

    Beijing

  • Department of gastroenterology,the first affiliated hospital of Bengbu medical college

    Bengbu

  • Department of infectious disease,the first affiliated hospital of Bengbu medical college

    Bengbu

  • Department of infectious disease,the No.123 hospital of PLA

    Bengbu

  • Department of gastroenterology of Cangzhou central hospital

    Cangzhou

  • Department of gastroenterology,the fourth hospital of Jilin university

    Changchun

  • Department of infectious disaese,the fourth hospital of Jilin unversity

    Changchun

  • Department of infectious disease of Changchun infectious disease hospital

    Changchun

  • Department of rhenmatism,the affiliated hospital to Changchun University of Chinese medicine

    Changchun

  • Department of infectious disease,people's hospital Changji hui autonomous prefecture Xinjiang

    Changji

  • 2st department of hepatology,the first hospital of Changsha

    Changsha

  • 5st internal meidcine of Hunan chest hospital

    Changsha

  • Department of breast disease,the affiliated cancer hospital of Xiangya school

    Changsha

  • Department of infectious disease of Hunan provincial people's hospital

    Changsha

  • Department of infectious disease of Xiangya hospital central south university

    Changsha

  • Department of infectious disease,the second Xiangya hospital of central south university

    Changsha

  • Department of infectious disease,the third Xiangya hospital of central south university

    Changsha

  • Department of tuberculosis of Changsha central hospital

    Changsha

  • Department of infectious disease,Heping hospital affiliated to Changzhi medical university

    Changzhi

  • Department of hepatology of Chengdu tenth people's hospital

    Chendu

  • Department of gastroenterlogy,affiliated hospital of Chenfdu University

    Chengdu

  • Department of gastroenterology,the 416th hospital of CNNC

    Chengdu

  • Department of gastroenterology of Chenzhou No.1 people's hospital

    Chenzhou

  • Department of hepatology of Chenzhou No.2 people's hospital

    Chenzhou

  • Department of infectious disease,the fourth people's hospital of Chenzhou

    Chenzhou

  • Department of infectious disease,the people's hospital of Chizhou

    Chizhou

  • Department of hepatology,Chongqing hospital of TCM

    Chongqing

  • Department of infectious disease of southwest hospital

    Chongqing

  • Department of infectious disease,the second affiliated hospital of Chongqing medical university

    Chongqing

  • Department of gastroenterology of Daqing oilfield general hospital

    Daqing

  • Department of infectious disease of Daqing second hospital

    Daqing

  • Department of hepatology of Datong fourth people's hospital

    Datong

  • Department of gastroenterology,Qilu hospital of Shandong university

    Dongying

  • Department of infectious disease of Shengli oilfield general hospital

    Dongying

  • Department of infectious disease ，Shengli hospital of Shengli oilfield administration

    Dongying

  • Department of infectious disease of Shanxi province Fenyang hospital

    Fenyang

  • Department of infectious disease of Foshan first people's hospital

    Foshan

  • Department of infectious disease of Fujian province Fuqing city hospital

    Fuqing

  • Department of hepatologym,No.2 people's hospital of Fuyang

    Fuyang

  • Department of hepatic-biliary medicine,Fuzhou general hospital of Nanjing military command

    Fuzhou

  • Department of hepatic-biliary medicine,No.476 hospital of PLA

    Fuzhou

  • Department of hepatology of Fuzhou infectious disease hospital

    Fuzhou

  • Department of digestive of Guangdong general hospital

    Guangdong

  • Deaprtment of gastroenterology of Guangzhou first people's hospital

    Guangzhou

  • Department of gastroenterology of Guagdong general hospital

    Guangzhou

  • Department of gsatroenterology of Sun Yat-sen memorial hspital, Sun Yat-sen university

    Guangzhou

  • Department of infectious disease of Guangzhou women&children medical center

    Guangzhou

  • Department of infectious disease,Nanfang hospital of southern medical university

    Guangzhou

  • Department of science education&information of Guangzhou Huiai hospital

    Guangzhou

  • Department of hematology,the affiliated hospital of Guiyang medical university

    Guiyang

  • Department of infectious disease of Guizhou provincial people's hospital

    Guiyang

  • Department of infectious disease,the affiliated hospital of Guiyang medical university

    Guiyang

  • 10st department of internal medicine of Heilongjiang province center for tuberculosis control and prevention

    Haerbin

  • 1st mepartment of internal medicine Heilongjiang province center for tuberculosis control and prevention

    Haerbin

  • 4st department of internal medicine of Heilongjiang province center for tuberculosis control and prevention

    Haerbin

  • 5st department of internal medicine of Heilongjiang province center for tuberculosis control and prevention

    Haerbin

  • 7st department of internal medicine of Heilongjiang province center for tuberculosis control and prevention

    Haerbin

  • 8st department of internal medicine of Heilongjiang province center for tuberculosis control and prevention

    Haerbin

  • 9st department of internal medicine of Heilongjiang province center for tuberculosis control and prevention

    Haerbin

  • Department of infectious disease,No.211 hospital of PLA

    Haerbin

  • Department of infectious disease,the first affiliated hosptal of Haerbin medical university

    Haerbin

  • Department of infection of Hainan general hospital

    Hainan

  • Department of infectious disease of Hangzhou Xiaoshan district first people's hospital

    Hangzhou

  • Department of infectious disease of Sir Run Run Shaw hospital,Zhejiang unicersity school of medicine

    Hangzhou

  • 1st department of respiration of Hanzhong second people's hospital

    Hanzhong

  • Department of infection of Hanzhou first people's hospital

    Hanzhou

  • Department of gastroenterology,the first affiliated hospital of Anhui medical university

    Hefei

  • Department of infectious disease of Anhui provincial hospital

    Hefei

  • Department of infectious disease of Hefei infectious disease hospital

    Hefei

  • Department of infectious disease,No.105 hospital of PLA

    Hefei

  • Department of infectious disease,the first affiliated hospital of Anhui university of Chinese medicine

    Hefei

  • Department of hematology of First affiliated hospital,Heilongjiang university of Chinese medicine

    Heilongjiang

  • Department of infectious disease,the first affiliated hospital of university of south China

    Hengyang

  • Department of hepatology of Hohhot second hospital

    Hohhot

  • Department of hepatology of Huai'an No.4 people's hospital

    Huai'an

  • department of oncology,Huaiyin hospital of Huai'an city

    Huai'an

  • Department of infectious disease of Yili friendship hospital

    Huiyuan

  • Department of infectious disease,people's hospital of Puluo county

    Huizhou

  • Department of oncology,people's hospital of Puluo county

    Huizhou

  • Department of gastroenterology of inner mongolia forestry general hospital

    Inner Mongolia

  • Department of hepatology of Inner Mongolia international Mongolian medicine hospital

    Inner Mongolia

  • Department of hepatology of No.253 hospital of the PLA

    Inner Mongolia

  • Department of infection, the affiliated hospital of inner mongolia medical hospital

    Inner Mongolia

  • Department of infection,the first affiliated hospital of Baotou medical university

    Inner Mongolia

  • Department of infectious disease of inner mongolia people's hospital

    Inner Mongolia

  • Department of tuberculosis of The Inner Mongolia Autonomous Region fourth hospital

    Inner Mongolia

  • Department of hematology, first affiliated hospital of Jiamusi university

    Jiamusi

  • Internal medicine,the 404 hospital of China national nuclear

    Jiayuguan

  • Department of gastroenterology of Beihua university affiliated hospital

    Jilin City

  • Department of gastroenterology,hepatology hospital of Jilin province

    Jilin City

  • Department of gastroentrology of Jilin integrated TCM&western medicine hospital

    Jilin City

  • Department of hepatology,hepatology hospital of Jilin province

    Jilin City

  • Department of hepatology,the first hospital oof Jilin university

    Jilin City

  • Department of infectious disease of Beihua university affiliated hospital

    Jilin City

  • 1st department of hepatology of Jinan hospital for infectious disease

    Jinan

  • Department of endocrinology of Shangdong provincial hospital

    Jinan

  • Department of gastroenterology of Jinan central hospital

    Jinan

  • Department of gastroenterology,Qilu hospital of Shandong university

    Jinan

  • Department of gastroenterology,the second hospital of Shandong university

    Jinan

  • Department of hepatology of Shandong province Qianfoshan hospital

    Jinan

  • Department of hepatology of Shandong provincial hospital of Chinese medicine

    Jinan

  • Department of rheumatology of Shandong provincial hospital

    Jinan

  • Internal medicine of Jinan city Lixia district people's hospital

    Jinan

  • Department of infectious disease of Jincheng anthracite mining group general hospital

    Jincheng

  • Department of infectious disease of Zezhou county people's hospital

    Jincheng

  • 2st department of hepatology of Jingmen No.2 people's hospital

    Jingmen

  • Department of gastroenterology of Jingmen No.1 people's hospital

    Jingmen

  • Department of gastroenterology ward 2 of Jingmen No.1 people's hospital

    Jingmen

  • Department of infectious disease of Jingmen No.2 people's hospital

    Jingmen

  • 1st internal medicine of Jingzhou hospital for infectious disease

    Jingzhou

  • Department of infectious disease of Jingzhou central hospital

    Jingzhou

  • Department of gastroenterology of Jinzhong City Yuci district people's hospital

    Jinzhong

  • Department of gastroenterology of Qixian county people's hospital

    Jinzhong

  • Department of gastroenterology,the second people's hospital of Jinzhong

    Jinzhong

  • Department of gastroentrology,the first people's hospital of Jinzhong

    Jinzhong

  • Department of infectious disease,the first affiliated hospital of Henan university

    Kaifeng

  • Department of infectious disease of Kashgar prefecture first people's hospital

    Kashgar

  • Department of gastroenterology of Xishan district people's hospital

    Kunming

  • Department of gastroenterology of Yunnan first people's hospital

    Kunming

  • Department of gastroenterology,the first affiliated hospital of Kunming medical university

    Kunming

  • Department of gastroentrology,the first hospital of Kunming

    Kunming

  • Department of infectious disease,Kunming general hospital of Chengdu military

    Kunming

  • Department of infectious disease,the first affiliated hospital of Kunming medical university

    Kunming

  • Department of rheumatology of Yunnan first people's hospital

    Kunming

  • Hepatology center,the second affiliated hospital of Kunming medical university

    Kunming

  • Department of hepatology, Gansu provincial hospital of TCM

    Lanzhou

  • Department of infectious disease of Lanzhou military general hospital

    Lanzhou

  • Department of infestious disease,the first hospital of Lanzhou university

    Lanzhou

  • outpatient of pulmonary hospital of Lanzhou

    Lanzhou

  • Department of infectious disease of Leqing people's hospital

    Leqing

  • Department of hepatology of Liaocheng city infectious disease hospital

    Liaocheng

  • Department of hepatology &respiration of Linfen infectious disease hospital

    Linfen

  • Department of endocrinolnogy of Linyi people's hospital

    Linyi

  • Department of hepatology of Linyi people's hospital

    Linyi

  • Department of tuberculosis of Linyi people's hospital

    Linyi

  • Department of gastroenterology of Lu'an people's hospital

    Lu'an

  • Department of gastroenterology of Luoyang third people's hospital

    Luoyang

  • Department of infectious disease of Luoyang central hospital

    Luoyang

  • Department of infectios disease,the affiliated hospital of southwest hospital

    Luzhou

  • Department of hepatology ward 1 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of hepatology ward 2 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of hepatology wardf 10 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of hepatology wardf 3 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of hepatology wardf 4 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of hepatology wardf 9 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of tuberculosis of ward 11 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of tuberculosis ward 5 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of tuberculosis ward 6 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of tuberculosis ward 7 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of tuberculosis ward 8 of Mudanjiang Kangan hospital

    Mudanjiang

  • Department of gastroenterology of Jiangxi provincial people's hospital

    Nanchang

  • Department of gastroenterology of the second affiliated hospital to Nanchang university

    Nanchang

  • Department of tuberculosis of Jiangxi provincial chest hospital

    Nanchang

  • Deparment of oncology, Nanjing hospital of TCM

    Nanjing

  • Department of hematology of Nanjing Jiangning hospital

    Nanjing

  • Department of hematology, Jiangsu province hospital of TCM

    Nanjing

  • Department of hepatology,No.81 hospital of PLA

    Nanjing

  • Department of infection of Jiangsu province hospital

    Nanjing

  • Department of infection of Nanjing drum tower hospital

    Nanjing

  • Department of infection,the second hospital of Nanjing

    Nanjing

  • Department of infectious disease of Nanjing Jiangbei people's hospital

    Nanjing

  • Department of infectious,Jiangsu procince hospital of TCM

    Nanjing

  • Department of oncology , Jiangning hospital of Nanjing city

    Nanjing

  • Department on tuberculosis of Nanjing chest hospital

    Nanjing

  • Department of gastroenterology,the first affiliated hospital of Guangxi medical university

    Nanning

  • Department of hepatology,the first affiliated hospital of Guangxi university of Chinese medicine

    Nanning

  • Department of oncology，the first affiliated hospital of Guangxi university of Chinese medicine

    Nanning

  • Department of gastroenterology of Ningbo medical treatment center Lihuili hospital

    Ningbo

  • Department of gastroenterology,Yinzhou hospital affiliated to medical school of Ningbo university

    Ningbo

  • Department of hematology of Ningbo medical treatment center Lihuili hospital

    Ningbo

  • Department of hepatology of Ningbo No.2 hospital

    Ningbo

  • Department of hepatology,No.113 hospital of PLA

    Ningbo

  • Department of psychiatry of Ningbo Kangning hospital

    Ningbo

  • Department of infectious disaese of Erdos second people's hospital

    Ordos

  • Department of oncology of Jungar Banner central hospital

    Ordos

  • Department of tuberculosis of Pingdingshan third people's hospital

    Pingdingshan

  • Department of gastroenterology of Jiangxi Pingxiang people's hospital

    Pingxiang

  • Department of gastroenterology,Pingxiang city hospital of Chinese medicine

    Pingxiang

  • Department of infedtious disease of Pingyang county hospital of Chinese medicine

    Pingyang

  • Department of infectious disease,Puyang oilfield general hospital

    Pujiang

  • Department of tuberculosis,the fifth people hospital of Puyang

    Pujiang

  • Department of digestive,the affiliated hospital of Qingdao university

    Qingdao

  • Department of endocrinology,the affiliated hospital of Qingdao university

    Qingdao

  • Department of gastroenterology of Qingdao municipal hospital

    Qingdao

  • Department of hepatology,the affiliated hospital of Qingdao university

    Qingdao

  • Department of digestive of Qinghai provincial people's hospital

    Qinghai

  • Department of hepatology,Qinghai province hospital for infectious disease

    Qinghai

  • Deqpartment of gastroenterology of Qinghai university affiliated hospital

    Qinghai

  • Department of gastroenterology,the third hosital of Qinhuangdao

    Qinhuangdao

  • Department of hepatology,the third hospital of Qinhuangdao

    Qinhuangdao

  • Department of infectious disease of Qiqihar infectious disease hospital

    Qiqihar

  • Department og gastroenterology,the first hospital of Qiqihar city

    Qiqihar

  • Department of infectious disease of Ruian people's hospital

    Ruian

  • Department of gastroenterology of Sanmenxia central hospital

    Sanmenxia

  • Department of hematology of Sanmenxia central hospital

    Sanmenxia

  • Department of infectious disease of Sanmenxia central hospital

    Sanmenxia

  • Department of gastroenterology,No.301 hospital Sanya branch

    Sanya

  • Clinical research center for tuberculosis of Shanghai pulmonary hospital

    Shanghai

  • Department of Digestive Diseases of Shanghai Tongji Hospital

    Shanghai

  • Department of Digestive Diseases of The Renji Hospital

    Shanghai

  • Department of digestive of Shanghai Tongji hospital

    Shanghai

  • Department of gastroenterolgy of Huadong hispital affiliated to Fudan university

    Shanghai

  • Department of gastroenterology,the affiliated Zhongshan hospital of Fudan university

    Shanghai

  • Department of hepatocirrhosis of Shuguang hospital affiliated Shanghai University of T.C.M

    Shanghai

  • Department of hepatology of No.85 hospital of PLA

    Shanghai

  • Department of infection of No.85 hospital of PLA

    Shanghai

  • Department of Infection of Ruijin Hospital Shanghai Jiaotong University School of Medicine

    Shanghai

  • Department of infectious disease of Longhua hospital affiliated to Shianghai univesity of Chinese medicine

    Shanghai

  • Department of infectious disease of Shanghai Songjiang district people's hospital

    Shanghai

  • Department of infectious disease of Tongren hospital

    Shanghai

  • Department of infectious disease,Huashan hospital affiliated to Fudan university

    Shanghai

  • Department of oncology of Shanghai Putuo district central hospital

    Shanghai

  • Department of oncology of the sixth people's hospital affiliated to Shanghai Jiaotong university

    Shanghai

  • Department of pediatrics of Shanghai first people's hospital Songjiang branch

    Shanghai

  • Department of digestive of the second affiliated hospital of Xi'an jiaotong university

    Shangxi

  • Department of infection of the second affiliated hospital of Xi'an jiaotong university

    Shangxi

  • Department of gastroenterology of Shanluo central hospital

    Shanluo

  • Department of infectious disease of Shanluo central hospital

    Shanluo

  • Department of infectious disease of Shaoxing central hospital

    Shaoxing

  • Department of infectious disease of Shaoyang central hospital

    Shaoyang

  • Department of infectious disease,Shengjing hospital of China medical university

    Shenyang

  • Department of hepatology of Shenzhen third people's hospital

    Shenzhen

  • Department of infectious disease of Shenzhen third people's hospital

    Shenzhen

  • Department of pulmonary dedicine of Shenzhen third people's hospital

    Shenzhen

  • Department of gastroenterology of Hebei general hospital

    Shijiazhuang

  • Department of gastroenterology,the first hospital of Hebei medical university

    Shijiazhuang

  • Department of hematology,the first hospital of Hebei medical university

    Shijiazhuang

  • Department of hepatology,the first hospital of Hebei medical university

    Shijiazhuang

  • Department of hepatology，the third hodpital of Hebei medical university

    Shijiazhuang

  • Department of tuberculosis of Hubei province chest hospital

    Shijiazhuang

  • 2st department of gastroenterology of Shiyan people's hospital

    Shiyan

  • Department of infectious disease of Dongfeng company general hospital

    Shiyan

  • Department of infectious disease of Taihe hospital

    Shiyan

  • Department of tuberculosis of Xiyuan hospital of Shiyan city

    Shiyan

  • Department of infestious disease,the first people's hospital of Shunde

    Shunde

  • Department of gastroenterology of Songyuan central hospital

    Songyuan

  • Department of hepatology of Jilin oilfiled general hospital

    Songyuan

  • Department of infectious disease of Suzhou municipal hospital

    Suzhou

  • Department of infectious disease,the fifth people's hospital of Suzhou

    Suzhou

  • Department of i fectious disease of Taian city central hospital

    Taian

  • Department of tuberculosis of Taian cancer hospital

    Taian

  • Department of gastroenterology,the second hospital of Shanxi medical university

    Taiyuan, Shanxi

  • 1st department of tuberculosis of Taiyuan fourth people's hospital

    Taiyuan

  • Department of hepatology,Shanxi provincial hospital of Chinese medicine

    Taiyuan

  • Department of tuberculosis of Taiyuan fourth people's hospital

    Taiyuan

  • Department of hematology&oncology,Taizhou hospital of Zhejiang province

    Taizhou

  • Department of infectious disease of Tianchang people's hospital

    Tianchang

  • Department of hepatology of Tianjin first hospital

    Tianjin

  • Department of hepatology of Tianjin third central hospital

    Tianjin

  • Department of hepatology,first teaching hospital of Tianjin university

    Tianjin

  • Department of hepatology,The affiliated hospital of logistics university of people's armed police force

    Tianjin

  • Department of oncology of Tianjin medical university general hospital

    Tianjin

  • Department of rheumatology of Tianjin first center hospital

    Tianjin

  • Department of infestious disaese of Tibet autonomous prefecture people's hospital

    Tibet

  • 1st department of oncology of Tonghua central hospital

    Tonghua

  • 3st department of oncology of Tonghua central hospital

    Tonghua

  • Department of oncology of Tonghua second people's hospital

    Tonghua

  • Department of oncology&hematology of Tonghua people's hospital

    Tonghua

  • Department of infectious disease of Tongliao infectious disease hospital

    Tongliao

  • Department of hepatology of The Xinjiang production and construction Corps hospital

    Ürümqi

  • Department of infectious disease of URUMQI friendship hospital

    Ürümqi

  • 2st department of tuberculosis of Weifang No.2 people's hospital

    Weifang

  • Department of gastroenterology of Weifang people's hospital

    Weifang

  • Department of gastroenterology of Weihai central hospital

    Weihai

  • Department of gastroenterology of Weihai municipal hospital

    Weihai

  • Department of infectious disease of Weinan central hospital

    Weinan

  • Department of infectious disease,the first people's hospital of Wenling

    Wenling

  • Department of hematology of the first affiliated hospital of Wenzhou medical university

    Wenzhou

  • Department of infectious disease of Wencheng county people's hospital

    Wenzhou

  • Department of infectious disease,Wenshou hospital of Chinesemedicine

    Wenzhou

  • Department of oncology of Wuhai people's hospital

    Wuhai

  • 1st internal medicine of Wuhan institute for tuberculosis control

    Wuhan

  • 3st internal medicine of Wuhan institute for tuberculosis control

    Wuhan

  • 4st internal medicine of Wuhan institute for tuberculosis control

    Wuhan

  • 5st internal medicine of Wuhan institute for tuberculosis control

    Wuhan

  • Departmeent of gastroenterology of fifth hodpital in Wuhan

    Wuhan

  • Department of gastroenterology of Wuhan integrated TCM&western medicine hospital

    Wuhan

  • Department of gastroenterology of Wuhan union hospiital

    Wuhan

  • Department of gastroenterology,the central hospital of Wuhan

    Wuhan

  • Department of gastroenterology,Wuhan general hospital of Guangzhou military

    Wuhan

  • Department of hepatology of Wuhan seventh hospital

    Wuhan

  • Department of hepatology,Hubei provincial hospital of TCM

    Wuhan

  • Department of hepatology,Wuhan general hospital of Guangzhou military

    Wuhan

  • Department of infectious disease of Puren hospital

    Wuhan

  • Department of infectious disease of Wuhan iron and steel(group) corp. staff hospital

    Wuhan

  • Department of infectious disease of Wuhan iron and steel(group) Crop. second staff hospital

    Wuhan

Other trials in China

About this study

Official title: A Retrospective Epidemiologic Study on Incidence and Treatment Status of Hospitalized Drug Induced Liver Injury Patients in Mainland China

This is a multi-center, open-enrollment, retrospective, non-interventional epidemiologic study without any clinical treatment. Its primary objective is to understand 1) incidence of drug-induced liver injury, including incidences among all the hospitalized patient, among patients in department of hepatic diseases, digestive diseases, oncology, hematology etc., individually; 2) epidemiologic characteristics of drug-induced liver injury, including suspected medications, clinical types, histological characteristics, severity and outcomes.

Read the detailed description

This is a multi-center, open-enrollment, retrospective, non-interventional epidemiologic study without any clinical treatment. Its primary objective is to understand 1) incidence of drug-induced liver injury, including incidences among all the hospitalized patient, among patients in department of hepatic diseases, digestive diseases, oncology, hematology etc., individually; 2) epidemiologic characteristics of drug-induced liver injury, including suspected medications, clinical types, histological characteristics, severity and outcomes.

It investigates medical records of patients who were hospitalized during 2012 to 2014. Those patients should be diagnosed as drug-induced liver injury, drug-induced liver disease, drug-induced hepatitis, drug-induced hepatocirrhosis, drug-induced hepatic failure, or any other similar diagnosis of drug-induced liver injury nature.

Keywords
Drug-Induced Liver Injury, DILI
Medical subject headings
Chemical and Drug Induced Liver Injury

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. diagnosis of drug-induced liver injury

    Measured: 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted3 Apr 2015 (estimated)
  2. Study startMar 2015
  3. Primary completionMay 2016
  4. Study completionJul 2016

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Time perspective
Retrospective
Enrolment
15,000 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT02407964
Sponsor's protocol ID
2012ZX09303-001
Acronym
DILI-R
Status last verified
Oct 2016
First submitted
31 Mar 2015
Last updated
26 Oct 2016
Results posted
No
Data monitoring committee
No
Individual data sharing
No

Publications

  • Li J, Zhang J, Xu X, Fang W, Qu S, Jin F, Zhou J, Han X, Raza HK, Li X, Mao Y. Hugan tablets for the treatment of RUCAM based drug-induced liver injury: a propensity score matching analysis using a nationwide database. Expert Rev Clin Pharmacol. 2021 Dec;14(12):1543-1550. doi: 10.1080/17512433.2021.1981859. Epub 2021 Sep 22.

    PubMed 34521298

Questions about this trial

What is this clinical trial studying?

An observational study of Drug-Induced Liver Injury, run by Drug Induced Liver Disease Study Group at 371 sites in China.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 26 Oct 2016. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 371 sites in China. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

diagnosis of drug-induced liver injury (time frame: 6 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT02407964, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Oct 2016.

AzTrials uses cookies for analytics and advertising. You can accept or reject them; the site works either way. Privacy Policy.

Free account

Log in to keep searching

You’ve used your 3 free searches. AzTrials is free: log in or create a free account to keep searching clinical trials and save the ones you want to follow.

Create a free accountLog in