Carotid ArteriesCAMIA2NCT02804659
Physiopathological and Therapeutic Value of microRNA in the Progression of Carotid Artery Plaques: Carotid Protocol and microRNA
An observational study of Carotid Arteries, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
Trial summary
Molecular analysis of the atheroma plaque. Screening for a novel biomarker of carotid status. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Carotid Arteries
- What is being tested?
- microRNA
- How many people
- 14 participants
- Where
- 1 siteFrance
- Study dates
- 26 Mar 2015to 26 Feb 2018
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adults having to undergo carotid thrombendarteriectomy
Who may be able to join
- Adults having to undergo carotid thromboendarteriectomy
- social security coverage
- provision of study information
- consent to participation.
Who cannot join
- Previous carotid artery surgery
- refusal to participate in the study
- or inability to give consent.
Trial locations and contacts
1 site in 1 country.
About this study
Molecular analysis of the atheroma plaque. Screening for a novel biomarker of carotid status.
- Conditions
- Carotid Arteries
- Being tested
- microRNA
- Keywords
- micro-RNA
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
microRNAOther
Extraction of the microRNA using the mirVana miRNA isolation kit and quantification using real-time PCRs
What is being measured
The primary outcome is the main question the study is designed to answer.
expression level of the seven miRNAs of interest
expression level of the seven miRNAs of interest in the serum and in carotid artery plaques : miR-100, miR-125a, miR-127, miR-133a, miR-145, miR-221
Measured: Day of surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Jun 2016 (estimated)
- Study start26 Mar 2015
- Primary completion26 Feb 2018
- Study completion26 Feb 2018
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Carotid ArteriesStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire, AmiensThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 14 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Pierre MAITRIAS, PhD, Principal investigator, CHU Amiens
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02804659
- Sponsor's protocol ID
- PI2014_843_0024
- Acronym
- CAMIA2
- Status last verified
- Jun 2026
- First submitted
- 15 Jun 2016
- Last updated
- 12 Jun 2026
- Results posted
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Physiopathological and Therapeutic Value of microRNA in the Progression of Carotid Artery Plaques: Carotid Protocol and microRNA
- ClinicalTrials.gov ID
- NCT02804659
- Acronym / sponsor ID
- CAMIA2 / PI2014_843_0024
- Conditions
- Carotid Arteries
- Keywords
- micro-RNA
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 14 participants (actual)
- Lead sponsor
- Centre Hospitalier Universitaire, AmiensUniversity, hospital or other
- Study start
- 26 Mar 2015 (actual)
- Primary completion
- 26 Feb 2018 (actual)
- Study completion
- 26 Feb 2018 (actual)
- First posted
- 17 Jun 2016 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Molecular analysis of the atheroma plaque. Screening for a novel biomarker of carotid status.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adults having to undergo carotid thrombendarteriectomy
Key inclusion criteria (4 listed)
- Adults having to undergo carotid thromboendarteriectomy
- social security coverage
- provision of study information
- consent to participation.
Key exclusion criteria (3 listed)
- Previous carotid artery surgery
- refusal to participate in the study
- or inability to give consent.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| microRNAExtraction of the microRNA using the mirVana miRNA isolation kit and quantification using real-time PCRs | Other | – |
Primary outcome
expression level of the seven miRNAs of interest
Time frame: Day of surgery
expression level of the seven miRNAs of interest in the serum and in carotid artery plaques : miR-100, miR-125a, miR-127, miR-133a, miR-145, miR-221
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Jun 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Pierre MAITRIAS, PhD principal investigator
CHU Amiens
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Carotid Arteries, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 12 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
expression level of the seven miRNAs of interest (time frame: Day of surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Jun 2026.