Blood PressureCHAPNCT02994680
Cardiopulmonary Outcomes and Household Air Pollution Trial
A study testing Three-burner LPG stove, Delivery of LPG tanks and Vouchers for LPG tanks in people with Blood Pressure and Carotid Intima Media Thickness, run by Johns Hopkins Bloomberg School of Public Health at 1 site in Peru.
Trial summary
The purpose of this randomized controlled field trial is to determine whether a liquefied petroleum gas (LPG) stove and fuel distribution intervention reduces personal and kitchen exposure to household air pollutants and improves cardiopulmonary health outcomes when compared to usual cooking practices with open-fire… Read more about this study
- Who is it for?
- Ages 25 to 64 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Blood Pressure, Carotid Intima Media Thickness, Endothelial Function
- What is being tested?
- Three-burner LPG stove, Delivery of LPG tanks and Vouchers for LPG tanks
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 181 participants
- Where
- 1 sitePeru
- Study dates
- 18 Jan 2017to 15 Feb 2019
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 25 to 64 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Female
- Full-time resident ≥6 months in current location
- Capable of understanding procedures
- Capable of providing informed consent and responding to a questionnaire
- Primary household cook
- Currently using a traditional stove as primary stove for cooking
- Cooking room/area separate from sleeping room/area to minimize probability of use of biomass fuel stoves for heating living space.
Who cannot join
- Plans to move from the area within one year
- Uncontrolled hypertension
- Diagnosis of chronic obstructive pulmonary disease (COPD)
- Pregnant or planning pregnancy in the next year
Trial locations and contacts
1 site in 1 country.
Peru1 site
Puno Global Non-Communicable Disease Research Site, School of Medicine, Johns Hopkins University
Puno
About this study
Official title: Effects of a Liquefied Petroleum Gas Stove and Fuel Distribution Intervention on Adult Cardiopulmonary Health Outcomes in Puno, Peru
The purpose of this randomized controlled field trial is to determine whether a liquefied petroleum gas (LPG) stove and fuel distribution intervention reduces personal and kitchen exposure to household air pollutants and improves cardiopulmonary health outcomes when compared to usual cooking practices with open-fire biomass-burning stoves in adult women aged 25-64 years.
Read the detailed description
Randomized, controlled field trial of an LPG stove and fuel distribution intervention compared to standard cooking practices with open-fire biomass-burning stoves in the homes of participating adult women aged 25-64 years. The aim is to determine whether provision of cleaner fuels will result in important reductions in household air pollutants and consequently in an improvement in cardiopulmonary health outcomes over a one-year period. Participants randomly assigned to the intervention arm will receive a free LPG stove and fuel delivered to their homes during the one-year intervention period. Participants randomly assigned to the control arm will receive a free LPG stove and vouchers that can be used to obtain free fuel for an entire year at LPG fuel distribution centers at the end of the one-year intervention period. All participants will be followed for a second year to assess patterns and impacts of sustained use (intervention arm) and initial adoption (control arm).
- Conditions
- Blood Pressure, Carotid Intima Media Thickness, Endothelial Function, Signs and Symptoms, Respiratory, Respiratory Function Tests
- Being tested
- Three-burner LPG stove, Delivery of LPG tanks, Vouchers for LPG tanks
- Keywords
- Air Pollution, Liquefied Petroleum Gas, Cookstove, Behavioral Intervention, Propane Stove
- Medical subject headings
- Signs and Symptoms, Respiratory
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Three-burner LPG stoveDevice
Also called propane stove, SURGE three-burner liquefied petroleum gas stove
The intervention arm will receive a three-burner LPG stove upon enrollment. The control arm will receive the stove one year after enrollment.
Delivery of LPG tanksOther
Also called propane tank
One year supply of LPG fuel, in the form of delivery of 20 kg tank that holds 10 kg of LPG. Delivered to homes.
Vouchers for LPG tanksOther
Also called coupon
One year supply of LPG, in the form of vouchers to obtain a free LPG tanks from a distribution center. (Beginning one year after enrollment, for one year)
| Study group | Role | What they receive |
|---|---|---|
| Intervention arm | Experimental | Will receive:
1. Three-burner LPG stove (at enrollment)
2. Delivery of LPG tanks (beginning at enrollment for one year)
The study will be conducted over three years, with staggered enrollment over one year, one year of observations during the intervention period, and one year of follow-up observations after the intervention period for each participant.
Participants in the intervention arm will receive an LPG stove upon enrollment and the research team will deliver fuel twice monthly to their homes during the first year. Participants in the intervention arm will not receive fuel during the second year, but researchers will encourage these participants to continue using LPG fuel for cooking. Receives: Device: Three-burner LPG stove; Other: Delivery of LPG tanks |
| Control arm | Active comparator | Will receive:
1. Three-burner LPG stove (one year after enrollment)
2. Vouchers for LPG tanks (one year after enrollment)
Participants in the control arm but will not receive an LPG stove or fuel during the first year. Instead, participants will receive an LPG stove at the end of the first year and vouchers to obtain free fuel at distribution centers during the course of the second year. Receives: Device: Three-burner LPG stove; Other: Vouchers for LPG tanks |
What is being measured
The primary outcome is the main question the study is designed to answer.
Particulate matter of 2.5 μm in size (household air pollutant)
Specific Aim: Demonstrate sustained reductions in personal and kitchen particulate matter concentrations after distribution of an LPG stove and fuel tanks twice monthly over a one-year period.
Hypothesis: Use of LPG stoves for cooking by participants in the intervention arm will result in a sustained reduction in personal and kitchen air pollutant concentrations when compared to those with the control arm during the one year intervention period.
Measured: One year
Carbon monoxide (household air pollutant)
Specific Aim: Demonstrate sustained reductions in personal and kitchen carbon monoxide concentrations after distribution of an LPG stove and fuel tanks twice monthly over a one-year period.
Hypothesis: Use of LPG stoves for cooking by participants in the intervention arm will result in a sustained reduction in personal and kitchen carbon monoxide concentrations when compared to those with the control arm during the one year intervention period.
Measured: One year
Blood pressure (cardiovascular health endpoint)
Specific Aim: Demonstrate sustained reduction in blood pressure after LPG stove intervention.
Hypothesis: Women in the intervention arm will have lower blood pressure when compared with those in the control arm during the one year intervention period.
Measured: One year
Flow mediated dilation (cardiovascular health endpoint)
Specific Aim: Demonstrate a sustained improvement in endothelial function after LPG stove intervention.
Hypothesis: Women in the intervention arm will have better endothelial function as measured by flow mediated dilation when compared with those in the control arm during the one year intervention period.
Measured: One year
Carotid intima media thickness (cardiovascular health endpoint)
Specific Aim: Demonstrate lower progression in carotid intima media thickness after LPG stove intervention.
Hypothesis: Women in the intervention arm will have a lower rate of atherosclerosis progression as measured by carotid artery ultrasound assessment of the carotid intima-media complex over a one-year period when compared with those in the control arm during the one year intervention period.
Measured: One year
Respiratory symptoms (respiratory health endpoint)
Specific Aim: Demonstrate sustained reduction in respiratory symptoms after LPG stove intervention.
Hypothesis: Women in the intervention arm will have fewer respiratory symptoms as measured by a lower St. Georges Respiratory Symptoms Questionnaire score when compared with those in the control arm during the one year intervention period.
Measured: One year
Peak expiratory flow (respiratory health endpoint)
Specific Aim: Demonstrate sustained improvement in peak expiratory flow after LPG stove intervention.
Hypothesis: Women in the intervention arm will have a higher peak expiratory flow as measured by spirometry when compared with those in the control arm during the one year intervention period.
Measured: One year
Forced expiratory volume at one second (respiratory health endpoint)
Specific Aim: Demonstrate higher forced expiratory volumes at one second after LPG stove intervention.
Hypothesis: Women in the intervention arm will have higher height- and age-adjusted, pre- and post-bronchodilator forced expiratory volume at one second as measured by spirometry over a one-year period when compared with those in the control arm during the one year intervention period.
Measured: One year
Secondary outcomes (8)
Quality-adjusted life years
Specific Aim: Demonstrate improvements in quality of life scores after LPG stove intervention, as calculated by the Short Form-36 questionnaire.
Hypothesis: Women in the intervention arm will have better quality of life related score than those in the control arm at the end of the one year intervention period.
Measured: One year
Inflammatory metabolites
Specific Aim: Demonstrate reductions in inflammatory metabolites measured in urine and dot blood samples after LPG stove intervention.
Hypothesis: Women in the intervention arm will have lower concentrations of inflammatory metabolites in urine and dot blood samples when compared to those in the control arm during the one year intervention period.
Measured: One year
Compliance with stove use
Hypothesis: Stove use monitors will demonstrate >90% compliance with LPG stove use during the one-year intervention period in the LPG stoves of participants in the intervention arm.
Measured: One year
Exhaled carbon monoxide
Specific Aim: Demonstrate sustained lower exhaled carbon monoxide concentrations during the one-year intervention period.
Hypothesis: Personal exhaled carbon monoxide concentrations will be lower in participants in the intervention arm when compared to those in the control arm.
Measured: One year
Diet
Specific Aim: Document changes in diet after LPG stove intervention, as measured by 24-hour recalls.
Hypothesis: Women in the intervention arm will have a better diet than those in the control arm during the one year intervention period.
Measured: One year
Urinary sodium
Specific Aim: Document changes in salt intake after LPG stove intervention, as measured by 24-hour recalls.
Hypothesis: Women in the intervention arm will have lower urinary sodium than those in the control arm after the intervention.
Measured: One year
Percentage of households with sustained LPG stove use in intervention arm
Hypothesis: Participants in the intervention arm will continue to use their LPG stoves without stove stacking in the year following the intervention.
Measured: One year
Percentage of households who adopted LPG stove use in the control arm
Specific Aim: Characterize the percentage of participants in control arm who decided to adopt LPG stove use one year after the intervention.
Hypothesis: Participants in the control arm will adopt LPG stoves without stove stacking in the year following the intervention.
Measured: One year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Dec 2016 (estimated)
- Study start18 Jan 2017
- Primary completion15 Feb 2019
- Study completion15 Feb 2019
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Blood PressureStudies of the same condition, open and under way.
- More trials run by Johns Hopkins Bloomberg School of Public HealthThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Care provider, Investigator
- Enrolment
- 181 participants (actual)
Sponsor and investigators
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Sponsor type
- University, hospital or other
- Collaborators
- Washington University School of Medicine, University of Georgia, Emory University, Universidad Peruana Cayetano Heredia, Asociacion Benefica Prisma
- Responsible party
- Sponsor
- Investigators
- William N Checkley, MD, PhD, Principal investigator, Associate Professor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT02994680
- Sponsor's protocol ID
- IRB00007128
- Acronym
- CHAP
- Status last verified
- Jul 2020
- First submitted
- 28 Nov 2016
- Last updated
- 14 Oct 2022
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is no plan to share individual patient data (IPD).
Publications
Fandino-Del-Rio M, Goodman D, Kephart JL, Miele CH, Williams KN, Moazzami M, Fung EC, Koehler K, Davila-Roman VG, Lee KA, Nangia S, Harvey SA, Steenland K, Gonzales GF, Checkley W; Cardiopulmonary outcomes and Household Air Pollution trial (CHAP) Trial Investigators. Effects of a liquefied petroleum gas stove intervention on pollutant exposure and adult cardiopulmonary outcomes (CHAP): study protocol for a randomized controlled trial. Trials. 2017 Nov 3;18(1):518. doi: 10.1186/s13063-017-2179-x.
PubMed 29100550Fandino-Del-Rio M, Kephart JL, Williams KN, Shade T, Adekunle T, Steenland K, Naeher LP, Moulton LH, Gonzales GF, Chiang M, Hossen S, Chartier RT, Koehler K, Checkley W; Cardiopulmonary outcomes and Household Air Pollution (CHAP) Trial Investigators. Household Air Pollution Concentrations after Liquefied Petroleum Gas Interventions in Rural Peru: Findings from a One-Year Randomized Controlled Trial Followed by a One-Year Pragmatic Crossover Trial. Environ Health Perspect. 2022 May;130(5):57007. doi: 10.1289/EHP10054. Epub 2022 May 12.
PubMed 35549716Checkley W, Williams KN, Kephart JL, Fandino-Del-Rio M, Steenland NK, Gonzales GF, Naeher LP, Harvey SA, Moulton LH, Davila-Roman VG, Goodman D, Tarazona-Meza C, Miele CH, Simkovich S, Chiang M, Chartier RT, Koehler K; CHAP Trial Investigators. Effects of a Household Air Pollution Intervention with Liquefied Petroleum Gas on Cardiopulmonary Outcomes in Peru. A Randomized Controlled Trial. Am J Respir Crit Care Med. 2021 Jun 1;203(11):1386-1397. doi: 10.1164/rccm.202006-2319OC.
PubMed 33306939
Study at a glance
From the registry record, last updated by the sponsor on 14 Oct 2022. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of a Liquefied Petroleum Gas Stove and Fuel Distribution Intervention on Adult Cardiopulmonary Health Outcomes in Puno, Peru
- ClinicalTrials.gov ID
- NCT02994680
- Acronym / sponsor ID
- CHAP / IRB00007128
- Conditions
- Blood Pressure, Carotid Intima Media Thickness, Endothelial Function, Signs and Symptoms, Respiratory, Respiratory Function Tests
- Keywords
- Air Pollution, Liquefied Petroleum Gas, Cookstove, Behavioral Intervention, Propane Stove
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 181 participants (actual)
- Lead sponsor
- Johns Hopkins Bloomberg School of Public HealthUniversity, hospital or other
- Collaborators
- Washington University School of Medicine, University of Georgia, Emory University, Universidad Peruana Cayetano Heredia, Asociacion Benefica Prisma
- Study start
- 18 Jan 2017 (actual)
- Primary completion
- 15 Feb 2019 (actual)
- Study completion
- 15 Feb 2019 (actual)
- First posted
- 16 Dec 2016 (estimated)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this randomized controlled field trial is to determine whether a liquefied petroleum gas (LPG) stove and fuel distribution intervention reduces personal and kitchen exposure to household air pollutants and improves cardiopulmonary health outcomes when compared to usual cooking practices with open-fire biomass-burning stoves in adult women aged 25-64 years.
Detailed description
Randomized, controlled field trial of an LPG stove and fuel distribution intervention compared to standard cooking practices with open-fire biomass-burning stoves in the homes of participating adult women aged 25-64 years. The aim is to determine whether provision of cleaner fuels will result in important reductions in household air pollutants and consequently in an improvement in cardiopulmonary health outcomes over a one-year period. Participants randomly assigned to the intervention arm will receive a free LPG stove and fuel delivered to their homes during the one-year intervention period. Participants randomly assigned to the control arm will receive a free LPG stove and vouchers that can be used to obtain free fuel for an entire year at LPG fuel distribution centers at the end of the one-year intervention period. All participants will be followed for a second year to assess patterns and impacts of sustained use (intervention arm) and initial adoption (control arm).
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (care provider, investigator)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Intervention arm | Experimental | Device: Three-burner LPG stove, Other: Delivery of LPG tanksWill receive: 1. Three-burner LPG stove (at enrollment) 2. Delivery of LPG tanks (beginning at enrollment for one year) The study will be conducted over three years, with staggered enrollment over one year, one year of observations during the intervention period, and one year of follow-up observations after the intervention period for each participant. Participants in the intervention arm will receive an LPG stove upon enrollment and the research team will deliver fuel twice monthly to their homes during the first year. Participants in the intervention arm will not receive fuel during the second year, but researchers will encourage these participants to continue using LPG fuel for cooking. |
| Control arm | Active comparator | Device: Three-burner LPG stove, Other: Vouchers for LPG tanksWill receive: 1. Three-burner LPG stove (one year after enrollment) 2. Vouchers for LPG tanks (one year after enrollment) Participants in the control arm but will not receive an LPG stove or fuel during the first year. Instead, participants will receive an LPG stove at the end of the first year and vouchers to obtain free fuel at distribution centers during the course of the second year. |
Who may qualify
- Ages
- 25 to 64 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Female
- Full-time resident ≥6 months in current location
- Capable of understanding procedures
- Capable of providing informed consent and responding to a questionnaire
- Primary household cook
Key exclusion criteria (4 listed)
- Plans to move from the area within one year
- Uncontrolled hypertension
- Diagnosis of chronic obstructive pulmonary disease (COPD)
- Pregnant or planning pregnancy in the next year
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Three-burner LPG stoveAlso: propane stove, SURGE three-burner liquefied petroleum gas stoveThe intervention arm will receive a three-burner LPG stove upon enrollment. The control arm will receive the stove one year after enrollment. | Device | Control arm, Intervention arm |
| Delivery of LPG tanksAlso: propane tankOne year supply of LPG fuel, in the form of delivery of 20 kg tank that holds 10 kg of LPG. Delivered to homes. | Other | Intervention arm |
| Vouchers for LPG tanksAlso: couponOne year supply of LPG, in the form of vouchers to obtain a free LPG tanks from a distribution center. (Beginning one year after enrollment, for one year) | Other | Control arm |
Primary outcome
Particulate matter of 2.5 μm in size (household air pollutant)
Time frame: One year
Specific Aim: Demonstrate sustained reductions in personal and kitchen particulate matter concentrations after distribution of an LPG stove and fuel tanks twice monthly over a one-year period. Hypothesis: Use of LPG stoves for cooking by participants in the intervention arm will result in a sustained reduction in personal and kitchen air pollutant concentrations when compared to those with the control arm during the one year intervention period.
Carbon monoxide (household air pollutant)
Time frame: One year
Specific Aim: Demonstrate sustained reductions in personal and kitchen carbon monoxide concentrations after distribution of an LPG stove and fuel tanks twice monthly over a one-year period. Hypothesis: Use of LPG stoves for cooking by participants in the intervention arm will result in a sustained reduction in personal and kitchen carbon monoxide concentrations when compared to those with the control arm during the one year intervention period.
Blood pressure (cardiovascular health endpoint)
Time frame: One year
Specific Aim: Demonstrate sustained reduction in blood pressure after LPG stove intervention. Hypothesis: Women in the intervention arm will have lower blood pressure when compared with those in the control arm during the one year intervention period.
Flow mediated dilation (cardiovascular health endpoint)
Time frame: One year
Specific Aim: Demonstrate a sustained improvement in endothelial function after LPG stove intervention. Hypothesis: Women in the intervention arm will have better endothelial function as measured by flow mediated dilation when compared with those in the control arm during the one year intervention period.
Carotid intima media thickness (cardiovascular health endpoint)
Time frame: One year
Specific Aim: Demonstrate lower progression in carotid intima media thickness after LPG stove intervention. Hypothesis: Women in the intervention arm will have a lower rate of atherosclerosis progression as measured by carotid artery ultrasound assessment of the carotid intima-media complex over a one-year period when compared with those in the control arm during the one year intervention period.
Respiratory symptoms (respiratory health endpoint)
Time frame: One year
Specific Aim: Demonstrate sustained reduction in respiratory symptoms after LPG stove intervention. Hypothesis: Women in the intervention arm will have fewer respiratory symptoms as measured by a lower St. Georges Respiratory Symptoms Questionnaire score when compared with those in the control arm during the one year intervention period.
Peak expiratory flow (respiratory health endpoint)
Time frame: One year
Specific Aim: Demonstrate sustained improvement in peak expiratory flow after LPG stove intervention. Hypothesis: Women in the intervention arm will have a higher peak expiratory flow as measured by spirometry when compared with those in the control arm during the one year intervention period.
Forced expiratory volume at one second (respiratory health endpoint)
Time frame: One year
Specific Aim: Demonstrate higher forced expiratory volumes at one second after LPG stove intervention. Hypothesis: Women in the intervention arm will have higher height- and age-adjusted, pre- and post-bronchodilator forced expiratory volume at one second as measured by spirometry over a one-year period when compared with those in the control arm during the one year intervention period.
8 secondary outcomes
Quality-adjusted life years
Time frame: One year
Inflammatory metabolites
Time frame: One year
Compliance with stove use
Time frame: One year
Exhaled carbon monoxide
Time frame: One year
Diet
Time frame: One year
Urinary sodium
Time frame: One year
Percentage of households with sustained LPG stove use in intervention arm
Time frame: One year
Percentage of households who adopted LPG stove use in the control arm
Time frame: One year
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Oct 2022.
- Background: PubMed 29100550Fandino-Del-Rio M, Goodman D, Kephart JL, Miele CH, Williams KN, Moazzami M, Fung EC, Koehler K, Davila-Roman VG, Lee KA, Nangia S, Harvey SA, Steenland K, Gonzales GF, Checkley W; Cardiopulmonary outcomes and Household Air Pollution trial (CHAP) Trial Investigators. Effects of a liquefied petroleum gas stove intervention on pollutant exposure and adult cardiopulmonary outcomes (CHAP): study protocol for a randomized controlled trial. Trials. 2017 Nov 3;18(1):518. doi: 10.1186/s13063-017-2179-x.
- Derived from this study: PubMed 35549716Fandino-Del-Rio M, Kephart JL, Williams KN, Shade T, Adekunle T, Steenland K, Naeher LP, Moulton LH, Gonzales GF, Chiang M, Hossen S, Chartier RT, Koehler K, Checkley W; Cardiopulmonary outcomes and Household Air Pollution (CHAP) Trial Investigators. Household Air Pollution Concentrations after Liquefied Petroleum Gas Interventions in Rural Peru: Findings from a One-Year Randomized Controlled Trial Followed by a One-Year Pragmatic Crossover Trial. Environ Health Perspect. 2022 May;130(5):57007. doi: 10.1289/EHP10054. Epub 2022 May 12.
- Derived from this study: PubMed 33306939Checkley W, Williams KN, Kephart JL, Fandino-Del-Rio M, Steenland NK, Gonzales GF, Naeher LP, Harvey SA, Moulton LH, Davila-Roman VG, Goodman D, Tarazona-Meza C, Miele CH, Simkovich S, Chiang M, Chartier RT, Koehler K; CHAP Trial Investigators. Effects of a Household Air Pollution Intervention with Liquefied Petroleum Gas on Cardiopulmonary Outcomes in Peru. A Randomized Controlled Trial. Am J Respir Crit Care Med. 2021 Jun 1;203(11):1386-1397. doi: 10.1164/rccm.202006-2319OC.
- Individual participant dataSharing planned: No. There is no plan to share individual patient data (IPD).
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
William N Checkley, MD, PhD principal investigator
Associate Professor
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Three-burner LPG stove, Delivery of LPG tanks and Vouchers for LPG tanks in people with Blood Pressure and Carotid Intima Media Thickness, run by Johns Hopkins Bloomberg School of Public Health at 1 site in Peru.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 Oct 2022. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Peru. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Particulate matter of 2.5 μm in size (household air pollutant) (time frame: One year). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT02994680, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Oct 2022.