HealthyNCT03072420

Characterization of Fingertips Using MRI Images (FINGERS-COMPRESSION)

A study testing Compression of the fingertip under MRI. in people with Healthy, run by Hospices Civils de Lyon at 1 site in France.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

The objectives was to obtain MRI images of the index finger of the subjects without loading and with loadings (normal and shear forces from 1 to 4N). Read more about this study

Who is it for?: Ages 18 to 65 yearsHealthy volunteers can take part
Conditions the study is for: Healthy
What is being tested?: Compression of the fingertip under MRI.
Could I receive a placebo?: Yes, some participants may receive a placebo
How many people: 8 participants
Where: 1 siteFrance
Study dates: 21 Jul 2015to 24 Jul 2015
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 65 years
All sexes
Healthy volunteers accepted
Adult, Older adult

Who may be able to join

Active voluntary healthy adult aged 18 to 65, affiliated to a social security scheme
Stature between 170 and 179cm
Body mass index (BMI) between 20 and 25
No previous hand musculoskeletal disorders
Cognitive level compatible with oral communication, adherence to instructions and understanding of gestures
Having signed the consent to participate in the study

Who cannot join

the subject presents a neurological or orthopedic disorder ;
the subject presents a pathology that could disturb the task ;
the subject has an Magnetic Resonance Imaging (MRI) contraindication (wears a pacemaker, insulin pump, prothesis, etc, has claustrophobia, …)

Trial locations and contacts

1 site in 1 country.

France1 site

IFSTTAR
Bron, 69675

Other trials in France

About this study

Official title: Characterization of Fingertips Using MRI Images : Development of Mechanically Faithful Models Dedicated to Manipulation.

The objectives was to obtain MRI images of the index finger of the subjects without loading and with loadings (normal and shear forces from 1 to 4N).

Conditions: Healthy
Being tested: Compression of the fingertip under MRI.
Keywords: MRI, fingers compression

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Compression of the fingertip under MRI.Other
Compression of the fingertip by a static loading on the phalanx distal of the index of the subjects; Then also a shear stress in the transverse direction of the finger. The data provided by the MRI images will be geometric information such as the thickness of the skin and its possible variation as a function of the area of the finger, the total thickness of soft tissues in compression as a function of the variation in l The angle between the axis of the phalanx and the plane of contact; Mechanical type information relating to the displacements and reaction forces, to the internal deformations of the different areas of the finger.

Study groups in NCT03072420
Study group	Role	What they receive
Group no manual work or activity	Experimental	Subject with an office or student job. Receives: Other: Compression of the fingertip under MRI.
Group manual work	Sham comparator	Subject working in a manual or predominantly manual. Receives: Other: Compression of the fingertip under MRI.

What is being measured

The primary outcome is the main question the study is designed to answer.

Average fingertip deflection under compression
The different stresses will be: compression of the fingertip by a static loading on the phalanx distal of the index of the subjects; Then also a shear stress in the transverse direction of the finger.
Measured: Day 1

Secondary outcomes (1)

Average fingertip dimensions
In order to develop realistic biomechanical models of the fingers allowing the simulation of the grip, an essential step will be the experimental mechanical characterization of the distal phalanges.
Measured: Day 1

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

21 Jul 201524 Jul 2015

First posted7 Mar 2017
Study start21 Jul 2015
Primary completion24 Jul 2015
Study completion24 Jul 2015

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (1)Papers the sponsor has linked to this study.
Other trials for HealthyStudies of the same condition, open and under way.
More trials run by Hospices Civils de LyonThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Basic science
Allocation: Non-randomised
Intervention model: Parallel groups
Masking: None (open label)
Enrolment: 8 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT03072420
Sponsor's protocol ID: 69HCL16_0688
Status last verified: Aug 2025
First submitted: 21 Feb 2017
Last updated: 3 Sep 2025
Results posted: No
FDA-regulated drug: No
FDA-regulated device: No

Publications

Dallard J, Merlhiot X, Petitjean N, Duprey S. MRI-based experimentations of fingertip flat compression: Geometrical measurements and finite element inverse simulations to investigate material property parameters. J Biomech. 2018 Jan 23;67:166-171. doi: 10.1016/j.jbiomech.2017.11.024. Epub 2017 Nov 29.
PubMed 29217092

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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Study at a glance

From the registry record, last updated by the sponsor on 3 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Characterization of Fingertips Using MRI Images : Development of Mechanically Faithful Models Dedicated to Manipulation.
ClinicalTrials.gov ID: NCT03072420
Acronym / sponsor ID: 69HCL16_0688
Conditions: Healthy
Keywords: MRI, fingers compression
Study type: Interventional
Recruitment status: Completed
Enrolment: 8 participants (actual)
Lead sponsor: Hospices Civils de LyonUniversity, hospital or other
Study start: 21 Jul 2015 (actual)
Primary completion: 24 Jul 2015 (actual)
Study completion: 24 Jul 2015 (actual)
First posted: 7 Mar 2017 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

The objectives was to obtain MRI images of the index finger of the subjects without loading and with loadings (normal and shear forces from 1 to 4N).

Study design

Primary purpose: Basic science
Allocation: Non-randomised
Intervention model: Parallel groups
Masking: None (open label)
Number of arms: 2

Arm	Type	Receives
Group no manual work or activity	Experimental	Other: Compression of the fingertip under MRI.Subject with an office or student job.
Group manual work	Sham comparator	Other: Compression of the fingertip under MRI.Subject working in a manual or predominantly manual.

Who may qualify

Ages: 18 to 65 years
Sex: All
Healthy volunteers: Accepted
Age groups: Adult, Older adult

Key inclusion criteria (6 listed)

Active voluntary healthy adult aged 18 to 65, affiliated to a social security scheme
Stature between 170 and 179cm
Body mass index (BMI) between 20 and 25
No previous hand musculoskeletal disorders
Cognitive level compatible with oral communication, adherence to instructions and understanding of gestures

Key exclusion criteria (3 listed)

the subject presents a neurological or orthopedic disorder ;
the subject presents a pathology that could disturb the task ;
the subject has an Magnetic Resonance Imaging (MRI) contraindication (wears a pacemaker, insulin pump, prothesis, etc, has claustrophobia, …)

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Compression of the fingertip under MRI.Compression of the fingertip by a static loading on the phalanx distal of the index of the subjects; Then also a shear stress in the transverse direction of the finger. The data provided by the MRI images will be geometric information such as the thickness of the skin and its possible variation as a function of the area of the finger, the total thickness of soft tissues in compression as a function of the variation in l The angle between the axis of the phalanx and the plane of contact; Mechanical type information relating to the displacements and reaction forces, to the internal deformations of the different areas of the finger.	Other	Group manual work, Group no manual work or activity

Primary outcome

Average fingertip deflection under compression
Time frame: Day 1
The different stresses will be: compression of the fingertip by a static loading on the phalanx distal of the index of the subjects; Then also a shear stress in the transverse direction of the finger.

1 secondary outcome

Average fingertip dimensions
Time frame: Day 1

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 3 Sep 2025.
Results publication: PubMed 29217092Dallard J, Merlhiot X, Petitjean N, Duprey S. MRI-based experimentations of fingertip flat compression: Geometrical measurements and finite element inverse simulations to investigate material property parameters. J Biomech. 2018 Jan 23;67:166-171. doi: 10.1016/j.jbiomech.2017.11.024. Epub 2017 Nov 29.

Related trials for Healthy

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Trained vs. Untrained: Lower Extremity Pressure Changes
Trained Athletes, Untrained
Not yet recruitingPhase 1
Comparison of Pharmacokinetic/Pharmacodynamic Characteristics and Safety of GZR101-80 Injection With Separately Injected, Simultaneous Doses of GZR33 Injection and Insulin Aspart
Healthy Participants
Active, not recruitingPhase 2
Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers
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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Georges BARATON, MD principal investigator

IFSTTAR

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Compression of the fingertip under MRI. in people with Healthy, run by Hospices Civils de Lyon at 1 site in France.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 3 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Average fingertip deflection under compression (time frame: Day 1). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT03072420, which also lists 1 linked publication.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Sep 2025.