HealthyNCT03095794
Social Decision-making (SOCIAL-DECISION)
A study testing How people learn another's value preference during decision under risk, Neural mechanism of making a group decision under risk that influences on in-group members and Neural mechanism of making a group decision that influences on out-group members in people with Healthy, run by Hospices Civils de Lyon at 1 site in France.
Trial summary
The purpose of this study is to investigate neural mechanism of healthy humans underlying group decision making and compare it with that of individual decision-making. Using functional neuroimaging technology combining with computational modeling, we examine how the human brain process social information to make a… Read more about this study
- Who is it for?
- Ages 20 to 30 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- How people learn another's value preference during decision under risk, Neural mechanism of making a group decision under risk that influences on in-group members and Neural mechanism of making a group decision that influences on out-group members
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 145 participants
- Where
- 1 siteFrance
- Study dates
- 31 Jan 2015to 18 Jul 2016
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 30 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- healthy human adult
- normal vision
Who cannot join
- depression
- potential addiction to alcohol/ nicotine
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Brain Mechanism of Social Decision-making
The purpose of this study is to investigate neural mechanism of healthy humans underlying group decision making and compare it with that of individual decision-making. Using functional neuroimaging technology combining with computational modeling, we examine how the human brain process social information to make a decision within a group, which often guides humans to make a better decision using collective wisdom.
- Conditions
- Healthy
- Being tested
- How people learn another's value preference during decision under risk, Neural mechanism of making a group decision under risk that influences on in-group members, Neural mechanism of making a group decision that influences on out-group members, fMRI
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
How people learn another's value preference during decision under riskOther
The aim of this study is to investigate how an agent learns another's value preference when they should make decisions on behalf of another. This experiment consists of 3 parts(i) measuring individual's loss aversion; (ii) feedback based learning of another's value preference; (iii) and decisions on behalf of others.
Neural mechanism of making a group decision under risk that influences on in-group membersOther
how individuals evaluate the risk and the outcome when they should make a single agreement decision in a group that will influence every member's payoff regardless of individuals' decisions. For the first part of the experiment, we will measure the individual level of loss aversion which will be used as the parameter for controlling individual differences.
Neural mechanism of making a group decision that influences on out-group membersOther
Human is decimated with other species by delegation of one responsibility. Although the person who has no-interests with the outcome of decision, they should make a delegated decision. Therefore, this decision has influences on others who are not part of the group. The third party punishment (Juries decision making) is one example of the decision made by a group influencing the out group members.
fMRIOther
For neuroimaging passes, the expected duration of each of the experimental protocols is about 1h30 for tasks 1 and 2 and about 2h for task 3. The maximum period foreseen for neuroimaging tests is 3 years and will start as soon as possible. Completion of the behavioral tests.
| Study group | Role | What they receive |
|---|---|---|
| neural mechanisms of decision making | Experimental | Previous studies on how brain manages a value-based decision have been bounded to individual decisions. The current study will extend the understanding of social dimensions by answering four questions. Receives: Other: How people learn another's value preference during decision under risk; Other: Neural mechanism of making a group decision under risk that influences on in-group members; Other: Neural mechanism of making a group decision that influences on out-group members; Other: fMRI |
What is being measured
The primary outcome is the main question the study is designed to answer.
Brain activation associated with decision-making (fMRI, non-invasive measure)
1 hour in a fMRI scanner
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Mar 2017
- Study start31 Jan 2015
- Primary completion18 Jul 2016
- Study completion18 Jul 2016
Why it stopped: Insufficient on-site staff to manage study
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- More trials run by Hospices Civils de LyonThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 145 participants (actual)
Sponsor and investigators
- Lead sponsor
- Hospices Civils de Lyon
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Caroline DEMILY, MD, Principal investigator, CH le Vinatier
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03095794
- Sponsor's protocol ID
- 69HCL16_0679
- Status last verified
- Nov 2017
- First submitted
- 24 Mar 2017
- Last updated
- 28 Nov 2017
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 28 Nov 2017. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Brain Mechanism of Social Decision-making
- ClinicalTrials.gov ID
- NCT03095794
- Acronym / sponsor ID
- 69HCL16_0679
- Conditions
- Healthy
- Study type
- Interventional
- Recruitment status
- TerminatedReason stopped: Insufficient on-site staff to manage study
- Enrolment
- 145 participants (actual)
- Lead sponsor
- Hospices Civils de LyonUniversity, hospital or other
- Study start
- 31 Jan 2015 (actual)
- Primary completion
- 18 Jul 2016 (actual)
- Study completion
- 18 Jul 2016 (actual)
- First posted
- 30 Mar 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to investigate neural mechanism of healthy humans underlying group decision making and compare it with that of individual decision-making. Using functional neuroimaging technology combining with computational modeling, we examine how the human brain process social information to make a decision within a group, which often guides humans to make a better decision using collective wisdom.
Study design
- Primary purpose
- Basic science
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| neural mechanisms of decision making | Experimental | Other: How people learn another's value preference during decision under risk, Other: Neural mechanism of making a group decision under risk that influences on in-group members, Other: Neural mechanism of making a group decision that influences on out-group members, Other: fMRIPrevious studies on how brain manages a value-based decision have been bounded to individual decisions. The current study will extend the understanding of social dimensions by answering four questions. |
Who may qualify
- Ages
- 20 to 30 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- healthy human adult
- normal vision
Key exclusion criteria (2 listed)
- depression
- potential addiction to alcohol/ nicotine
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| How people learn another's value preference during decision under riskThe aim of this study is to investigate how an agent learns another's value preference when they should make decisions on behalf of another. This experiment consists of 3 parts(i) measuring individual's loss aversion; (ii) feedback based learning of another's value preference; (iii) and decisions on behalf of others. | Other | neural mechanisms of decision making |
| Neural mechanism of making a group decision under risk that influences on in-group membershow individuals evaluate the risk and the outcome when they should make a single agreement decision in a group that will influence every member's payoff regardless of individuals' decisions. For the first part of the experiment, we will measure the individual level of loss aversion which will be used as the parameter for controlling individual differences. | Other | neural mechanisms of decision making |
| Neural mechanism of making a group decision that influences on out-group membersHuman is decimated with other species by delegation of one responsibility. Although the person who has no-interests with the outcome of decision, they should make a delegated decision. Therefore, this decision has influences on others who are not part of the group. The third party punishment (Juries decision making) is one example of the decision made by a group influencing the out group members. | Other | neural mechanisms of decision making |
| fMRIFor neuroimaging passes, the expected duration of each of the experimental protocols is about 1h30 for tasks 1 and 2 and about 2h for task 3. The maximum period foreseen for neuroimaging tests is 3 years and will start as soon as possible. Completion of the behavioral tests. | Other | neural mechanisms of decision making |
Primary outcome
Brain activation associated with decision-making (fMRI, non-invasive measure)
Time frame: Day 1
1 hour in a fMRI scanner
Results and safety
The study was stopped early (reason given: Insufficient on-site staff to manage study). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Nov 2017.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Caroline DEMILY, MD principal investigator
CH le Vinatier
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing How people learn another's value preference during decision under risk, Neural mechanism of making a group decision under risk that influences on in-group members and Neural mechanism of making a group decision that influences on out-group members in people with Healthy, run by Hospices Civils de Lyon at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 28 Nov 2017. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: Insufficient on-site staff to manage study). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Brain activation associated with decision-making (fMRI, non-invasive measure) (time frame: Day 1). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Nov 2017.