Diet, Food, and NutritionNCT03335644
The NutriNet-Santé Study
An observational study of Diet, Food, and Nutrition and Exercise, run by University of Paris 13 at 1 site in France.
Trial summary
The NutriNet-Santé study was set up to investigate nutrition and health relationships. Specifically, it was the first web-based cohort worldwide on such a large scale (n=171 000 as of 2021) focused on the complex link between nutrition and health status. Read more about this study
- Who is it for?
- Ages 15 years and olderHealthy volunteers can take part
- Conditions the study is for
- Diet, Food, and Nutrition, Exercise, Diseases Category
- How many people
- 170,000 participants
- Where
- 1 siteFrance
- Study dates
- 11 May 2009to 11 May 2029
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 years and older
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: The NutriNet-Santé study is a French ongoing web-based cohort launched in 2009 with the objective to study the associations between nutrition and health as well as the determinants of dietary behaviors and nutritional status. This cohort has been previously described in details (citations). Participants aged over 15 years with access to the Internet are recruited by vast multimedia campaigns. All questionnaires are completed online using a dedicated website (www.etude-nutrinet-sante.fr).
Who may be able to join
- aged over 15 years
- access to internet
Who cannot join
- aged under 15 years
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
EREN
Bobigny, Seine Saint Denis, 93017
Mathilde Touvier, Dr, +33148388933, m.touvier@eren.smbh.univ-paris13.fr
Pilar Galan, Dr
About this study
Official title: The NutriNet-Santé Study. A Web-based Prospective Cohort Study of the Relationship Between Nutrition and Health and of Dietary Patterns and Nutritional Status Predictors
The NutriNet-Santé study was set up to investigate nutrition and health relationships. Specifically, it was the first web-based cohort worldwide on such a large scale (n=171 000 as of 2021) focused on the complex link between nutrition and health status. It is characterized by a very detailed assessment of nutritional exposure and dietary behavior.
https://etude-nutrinet-sante.fr/ https://info.etude-nutrinet-sante.fr/en
Read the detailed description
NutriNet-Santé is a large-scale (n=171,000) web-based cohort coordinated by EREN, launched in France in 2009 to investigate nutrition and health relationships. All required ethics authorisations have been obtained (listed here). NutriNet-Santé participants regularly fill questionnaires through a dedicated and secure website, providing extensive, high-quality nutritional and non-nutritional data, including repeated data on socio-demographics and lifestyle (yearly), anthropometrics (every 6 months), dietary intake (every 6 months), physical activity (IPAQ questionnaire, yearly)5 and health status (every 6 months). NutriNet-Santé is characterised by a very detailed and up-to-date assessment of nutritional exposure and dietary behaviours. Usual dietary intakes are assessed at baseline and every 6 months thereafter through a series of 3 non-consecutive randomly assigned 24h dietary records. Daily energy, alcohol, micro- and macronutrient intakes are calculated using the published NutriNet-Santé food composition database (>3,500 generic items). All major health events (e.g., cancers, cardio- and cerebrovascular diseases) are reported by the participants and validated by an expert committee of physicians based on medical records, and/or retrieved from the French National Health Insurance medico-administrative databases to limit potential reporting bias. In turn, mortality data are obtained from the exhaustive French National Mortality Registry (CépiDC). The number of incident events already registered is as follows: 4,200 cancers and 1,240 deaths. A sub-sample of the cohort (n=20,000) provided blood and urine samples, currently stored at -80°C in EREN's biobank.
- Conditions
- Diet, Food, and Nutrition, Exercise, Diseases Category, Cohort Studies, Adult, Anthropometry
- Keywords
- determinants of dietary patterns and nutritional status, Food additives, Food processing, Exclusion diets, vegetarian diet, vegan diet, Organic food, pesticide exposure, sustainability, Gut microbiota, Food labeling, Dietary supplements, Food based dietary guidelines, Psychological determinants of food behavior, Geographical determinants of food behavior, Breastfeeding, Mental health, Cancer, Cardiovascular and cardiometabolic health, Multimorbidity
- Medical subject headings
- Motor Activity, Breast Feeding, Psychological Well-Being, Neoplasms
What is being measured
The primary outcome is the main question the study is designed to answer.
cancers using health questionnaire and/or the website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
CVD using health questionnaire and/or the dedicated website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
type 2 diabetes using health questionnaire and/or the website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
hypertension using health questionnaire and/or the website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
metabolic syndrome using health questionnaire and/or the website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
depression using health questionnaire and/or the website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
migraine using health questionnaire and/or the website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
rheumatoid arthritis using health questionnaire and/or the website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
cognitive decline using health questionnaire and/or the website for declaration of major health events
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
quality of life using the SF-36 questionnaire
self reported
Measured: every 6 months after registration, up to 10 years of follow-up
Weight using anthropometric questionnaire
self reported
Measured: every year after registration, up to 10 years of follow-up
Height using anthropometric questionnaire
self reported
Measured: every year after registration, up to 10 years of follow-up
Mortality
CepiDC exhaustive national registry
Measured: continuously updated
Mental health (incl. anxious disorders, sleep disorders, addictive behaviors, eating disorders)
self reported though validated scales and/or questionnaires
Measured: repeatedly during followup
SARSCOV-2 (Covid 19) infection
serology + questionnaires on symptoms
Measured: regular update for a subsampe of the cohort from 2020
multi-morbidity (mental and physical health)
combination of previsously listed mental and physical health outcomes
Measured: continuous update
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Nov 2017
- Study start11 May 2009
- Primary completion11 May 2029 (estimated)
- Study completion11 May 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (65)Papers the sponsor has linked to this study.
- Other trials for Diet, Food, and NutritionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 170,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Paris 13
- Sponsor type
- University, hospital or other
- Collaborators
- Institut National de la Santé Et de la Recherche Médicale, France, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Conservatoire national des Arts et Métiers
- Responsible party
- Principal investigator, Mathilde Touvier, University of Paris 13
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03335644
- Sponsor's protocol ID
- NutriNet-Santé
- Status last verified
- Jul 2021
- First submitted
- 11 Oct 2017
- Last updated
- 26 Jul 2021
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Hercberg S, Castetbon K, Czernichow S, Malon A, Mejean C, Kesse E, Touvier M, Galan P. The Nutrinet-Sante Study: a web-based prospective study on the relationship between nutrition and health and determinants of dietary patterns and nutritional status. BMC Public Health. 2010 May 11;10:242. doi: 10.1186/1471-2458-10-242.
PubMed 20459807Le Folcalvez X, Obeid E, Palomar-Cros A, Fezeu LK, Bourhis L, Bellicha A, Peneau S, Deschamps V, Deschasaux-Tanguy M, Touvier M, Hercberg S, Julia C, Kesse-Guyot E, Andreeva VA, Lassale C, Montagner A, Guillou H, Jacobi D, Srour B. Eating jetlag based on meal timing discrepancies and risk of cardiovascular disease using the prospective cohort NutriNet-Sante. Commun Med (Lond). 2026 Sep 1;6(1):453. doi: 10.1038/s43856-026-01758-5.
PubMed 42680779Hasenbohler A, Javaux G, Payen de la Garanderie M, Szabo de Edelenyi F, Bourhis L, Agaesse C, De Sa A, Huybrechts I, Pierre F, Coumoul X, Julia C, Kesse-Guyot E, Alles B, Fezeu LK, Hercberg S, Galan P, Deschasaux-Tanguy M, Chassaing B, Srour B, Touvier M. Food additive and naturally occurring glutamate and risk of cardiovascular diseases in the NutriNet-Sante prospective cohort. Am J Clin Nutr. 2026 Aug 8:101462. doi: 10.1016/j.ajcnut.2026.101462. Online ahead of print.
PubMed 42570865Hasenbohler A, Javaux G, Payen de la Garanderie M, Szabo de Edelenyi F, Yvroud-Hoyos P, Agaesse C, De Sa A, Huybrechts I, Pierre F, Coumoul X, Fezeu LK, Galan P, Blacher J, Julia C, Alles B, Hercberg S, Chassaing B, Deschasaux-Tanguy M, Srour B, Touvier M. Preservative food additives, hypertension, and cardiovascular diseases: the NutriNet-Sante study. Eur Heart J. 2026 May 20:ehag308. doi: 10.1093/eurheartj/ehag308. Online ahead of print.
PubMed 42161430Larnder AH, Murphy RA, Srour B, Dechamp N, Galan P, Hercberg S, Bourhis L, Diaz C, Genilloud O, Touvier M, Deschasaux-Tanguy M. Plasma metabolites, dietary intakes, and breast cancer incidence: a prospective case-cohort study in NutriNet-Sante. Am J Clin Nutr. 2026 Jul;124(1):101342. doi: 10.1016/j.ajcnut.2026.101342. Epub 2026 May 23.
PubMed 42114757Berlivet J, Meyer E, Alles B, Lairon D, Hercberg S, Touvier M, Srour B, Baudry J, Kesse-Guyot E. Consumption of organic compared with conventional fruits and vegetables in relation to cancer risk: findings from the NutriNet-Sante cohort study. Am J Clin Nutr. 2026 May;123(5):101284. doi: 10.1016/j.ajcnut.2026.101284. Epub 2026 Mar 19.
PubMed 41862000Hasenbohler A, Javaux G, Payen de la Garanderie M, Szabo de Edelenyi F, Bourhis L, Agaesse C, De Sa A, Huybrechts I, Pierre F, Coumoul X, Julia C, Kesse-Guyot E, Alles B, Fezeu LK, Hercberg S, Deschasaux-Tanguy M, Cosson E, Tatulashvili S, Chassaing B, Srour B, Touvier M. Associations between preservative food additives and type 2 diabetes incidence in the NutriNet-Sante prospective cohort. Nat Commun. 2026 Jan 7;16(1):11199. doi: 10.1038/s41467-025-67360-w.
PubMed 41501013Hasenbohler A, Javaux G, Payen de la Garanderie M, de Edelenyi FS, Yvroud-Hoyos P, Agaesse C, De Sa A, Huybrechts I, Pierre F, Audebert M, Coumoul X, Julia C, Kesse-Guyot E, Alles B, Deschamps V, Hercberg S, Chassaing B, Srour B, Deschasaux-Tanguy M, Touvier M. Intake of food additive preservatives and incidence of cancer: results from the NutriNet-Sante prospective cohort. BMJ. 2026 Jan 7;392:e084917. doi: 10.1136/bmj-2025-084917.
PubMed 41500678Cote M, Hutchinson JM, Touvier M, Srour B, Bourhis L, Lamarche B, Fezeu LK. Associations between Dietary Pattern Networks Derived from Machine Learning Algorithms and Cardiovascular Disease Risk in the NutriNet-Sante Cohort. J Nutr. 2025 Nov;155(11):4033-4042. doi: 10.1016/j.tjnut.2025.09.014. Epub 2025 Sep 22.
PubMed 40992665Paz-Graniel I, Kose J, Duquenne P, Babio N, Salas-Salvado J, Hercberg S, Galan P, Touvier M, Fezeu LK, Andreeva VA. Alcohol, Smoking, and Their Synergy as Risk Factors for Incident Type 2 Diabetes. Am J Prev Med. 2025 Nov;69(5):108011. doi: 10.1016/j.amepre.2025.108011. Epub 2025 Jul 31.
PubMed 40752888Berthy F, Toujgani H, Duquenne P, Fezeu LK, Lairon D, Pointereau P, Touvier M, Hercberg S, Galan P, Alles B, Baudry J, Kesse-Guyot E. Prospective association of the EAT-Lancet reference diet with body weight changes and incidence of overweight and obesity in a French cohort. Am J Clin Nutr. 2025 Aug;122(2):450-459. doi: 10.1016/j.ajcnut.2025.06.013. Epub 2025 Jun 17.
PubMed 40553762Toujgani H, Wang J, Perraud E, Baudry J, Berlivet J, Alles B, Fouillet H, Hercberg S, Touvier M, Lairon D, Pointereau P, Couturier C, Mariotti F, Kesse-Guyot E; TRANSFood Consortium. Dietary consumption trajectory profiles over time of French adults from the NutriNet-Sante cohort (2014-2022): multicriteria analysis of sustainability. Int J Behav Nutr Phys Act. 2025 Jun 13;22(1):76. doi: 10.1186/s12966-025-01777-w.
PubMed 40514663Paolassini-Guesnier P, Van Beekum M, Kesse-Guyot E, Baudry J, Shankland R, Rodhain A, Bellicha A, Leys C, Hercberg S, Touvier M, Alles B, Peneau S. Mindful eating is associated with a healthier plant-based diet in the NutriNet-Sante study. Sci Rep. 2025 Jun 6;15(1):19928. doi: 10.1038/s41598-025-02195-5.
PubMed 40481021Meyer E, Alles B, Berlivet J, Peneau S, Bellicha A, Touvier M, Langevin B, Pointereau P, Lairon D, Hercberg S, Kesse-Guyot E, Baudry J. Typology of out-of-home eaters: a description of sociodemographic, lifestyle, nutritional and environmental characteristics in the NutriNet-Sante cohort. Int J Behav Nutr Phys Act. 2025 May 26;22(1):61. doi: 10.1186/s12966-025-01752-5.
PubMed 40420193Payen de la Garanderie M, Hasenbohler A, Dechamp N, Javaux G, Szabo de Edelenyi F, Agaesse C, De Sa A, Bourhis L, Porcher R, Pierre F, Coumoul X, Kesse-Guyot E, Alles B, Fezeu LK, Cosson E, Tatulashvili S, Huybrechts I, Hercberg S, Deschasaux-Tanguy M, Chassaing B, Rytter H, Srour B, Touvier M. Food additive mixtures and type 2 diabetes incidence: Results from the NutriNet-Sante prospective cohort. PLoS Med. 2025 Apr 8;22(4):e1004570. doi: 10.1371/journal.pmed.1004570. eCollection 2025 Apr.
PubMed 40198579
Study at a glance
From the registry record, last updated by the sponsor on 26 Jul 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The NutriNet-Santé Study. A Web-based Prospective Cohort Study of the Relationship Between Nutrition and Health and of Dietary Patterns and Nutritional Status Predictors
- ClinicalTrials.gov ID
- NCT03335644
- Acronym / sponsor ID
- NutriNet-Santé
- Conditions
- Diet, Food, and Nutrition, Exercise, Diseases Category, Cohort Studies, Adult, Anthropometry
- Keywords
- determinants of dietary patterns and nutritional status, Food additives, Food processing, Exclusion diets, vegetarian diet, vegan diet, Organic food, pesticide exposure, sustainability, Gut microbiota, Food labeling, Dietary supplements, Food based dietary guidelines
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 170,000 participants (estimated)
- Lead sponsor
- University of Paris 13University, hospital or other
- Collaborators
- Institut National de la Santé Et de la Recherche Médicale, France, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Conservatoire national des Arts et Métiers
- Study start
- 11 May 2009 (actual)
- Primary completion
- 11 May 2029 (estimated)
- Study completion
- 11 May 2029 (estimated)
- First posted
- 8 Nov 2017 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The NutriNet-Santé study was set up to investigate nutrition and health relationships. Specifically, it was the first web-based cohort worldwide on such a large scale (n=171 000 as of 2021) focused on the complex link between nutrition and health status. It is characterized by a very detailed assessment of nutritional exposure and dietary behavior.
https://etude-nutrinet-sante.fr/ https://info.etude-nutrinet-sante.fr/en
Detailed description
NutriNet-Santé is a large-scale (n=171,000) web-based cohort coordinated by EREN, launched in France in 2009 to investigate nutrition and health relationships. All required ethics authorisations have been obtained (listed here). NutriNet-Santé participants regularly fill questionnaires through a dedicated and secure website, providing extensive, high-quality nutritional and non-nutritional data, including repeated data on socio-demographics and lifestyle (yearly), anthropometrics (every 6 months), dietary intake (every 6 months), physical activity (IPAQ questionnaire, yearly)5 and health status (every 6 months). NutriNet-Santé is characterised by a very detailed and up-to-date assessment of nutritional exposure and dietary behaviours. Usual dietary intakes are assessed at baseline and every 6 months thereafter through a series of 3 non-consecutive randomly assigned 24h dietary records. Daily energy, alcohol, micro- and macronutrient intakes are calculated using the published NutriNet-Santé food composition database (>3,500 generic items). All major health events (e.g., cancers, cardio- and cerebrovascular diseases) are reported by the participants and validated by an expert committee of physicians based on medical records, and/or retrieved from the French National Health Insurance medico-administrative databases to limit potential reporting bias. In turn, mortality data are obtained from the exhaustive French National Mortality Registry (CépiDC). The number of incident events already registered is as follows: 4,200 cancers and 1,240 deaths. A sub-sample of the cohort (n=20,000) provided blood and urine samples, currently stored at -80°C in EREN's biobank.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 15 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The NutriNet-Santé study is a French ongoing web-based cohort launched in 2009 with the objective to study the associations between nutrition and health as well as the determinants of dietary behaviors and nutritional status. This cohort has been previously described in details (citations). Participants aged over 15 years with access to the Internet are recruited by vast multimedia campaigns. All questionnaires are completed online using a dedicated website (www.etude-nutrinet-sante.fr).
Key inclusion criteria (2 listed)
- aged over 15 years
- access to internet
Key exclusion criteria (1 listed)
- aged under 15 years
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
cancers using health questionnaire and/or the website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
CVD using health questionnaire and/or the dedicated website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
type 2 diabetes using health questionnaire and/or the website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
hypertension using health questionnaire and/or the website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
metabolic syndrome using health questionnaire and/or the website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
depression using health questionnaire and/or the website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
migraine using health questionnaire and/or the website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
rheumatoid arthritis using health questionnaire and/or the website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
cognitive decline using health questionnaire and/or the website for declaration of major health events
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
quality of life using the SF-36 questionnaire
Time frame: every 6 months after registration, up to 10 years of follow-up
self reported
Weight using anthropometric questionnaire
Time frame: every year after registration, up to 10 years of follow-up
self reported
Height using anthropometric questionnaire
Time frame: every year after registration, up to 10 years of follow-up
self reported
Mortality
Time frame: continuously updated
CepiDC exhaustive national registry
Mental health (incl. anxious disorders, sleep disorders, addictive behaviors, eating disorders)
Time frame: repeatedly during followup
self reported though validated scales and/or questionnaires
SARSCOV-2 (Covid 19) infection
Time frame: regular update for a subsampe of the cohort from 2020
serology + questionnaires on symptoms
multi-morbidity (mental and physical health)
Time frame: continuous update
combination of previsously listed mental and physical health outcomes
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 26 Jul 2021.
- Results publication: PubMed 20459807Hercberg S, Castetbon K, Czernichow S, Malon A, Mejean C, Kesse E, Touvier M, Galan P. The Nutrinet-Sante Study: a web-based prospective study on the relationship between nutrition and health and determinants of dietary patterns and nutritional status. BMC Public Health. 2010 May 11;10:242. doi: 10.1186/1471-2458-10-242.
- Derived from this study: PubMed 42680779Le Folcalvez X, Obeid E, Palomar-Cros A, Fezeu LK, Bourhis L, Bellicha A, Peneau S, Deschamps V, Deschasaux-Tanguy M, Touvier M, Hercberg S, Julia C, Kesse-Guyot E, Andreeva VA, Lassale C, Montagner A, Guillou H, Jacobi D, Srour B. Eating jetlag based on meal timing discrepancies and risk of cardiovascular disease using the prospective cohort NutriNet-Sante. Commun Med (Lond). 2026 Sep 1;6(1):453. doi: 10.1038/s43856-026-01758-5.
- Derived from this study: PubMed 42570865Hasenbohler A, Javaux G, Payen de la Garanderie M, Szabo de Edelenyi F, Bourhis L, Agaesse C, De Sa A, Huybrechts I, Pierre F, Coumoul X, Julia C, Kesse-Guyot E, Alles B, Fezeu LK, Hercberg S, Galan P, Deschasaux-Tanguy M, Chassaing B, Srour B, Touvier M. Food additive and naturally occurring glutamate and risk of cardiovascular diseases in the NutriNet-Sante prospective cohort. Am J Clin Nutr. 2026 Aug 8:101462. doi: 10.1016/j.ajcnut.2026.101462. Online ahead of print.
- Derived from this study: PubMed 42161430Hasenbohler A, Javaux G, Payen de la Garanderie M, Szabo de Edelenyi F, Yvroud-Hoyos P, Agaesse C, De Sa A, Huybrechts I, Pierre F, Coumoul X, Fezeu LK, Galan P, Blacher J, Julia C, Alles B, Hercberg S, Chassaing B, Deschasaux-Tanguy M, Srour B, Touvier M. Preservative food additives, hypertension, and cardiovascular diseases: the NutriNet-Sante study. Eur Heart J. 2026 May 20:ehag308. doi: 10.1093/eurheartj/ehag308. Online ahead of print.
- Derived from this study: PubMed 42114757Larnder AH, Murphy RA, Srour B, Dechamp N, Galan P, Hercberg S, Bourhis L, Diaz C, Genilloud O, Touvier M, Deschasaux-Tanguy M. Plasma metabolites, dietary intakes, and breast cancer incidence: a prospective case-cohort study in NutriNet-Sante. Am J Clin Nutr. 2026 Jul;124(1):101342. doi: 10.1016/j.ajcnut.2026.101342. Epub 2026 May 23.
- Derived from this study: PubMed 41862000Berlivet J, Meyer E, Alles B, Lairon D, Hercberg S, Touvier M, Srour B, Baudry J, Kesse-Guyot E. Consumption of organic compared with conventional fruits and vegetables in relation to cancer risk: findings from the NutriNet-Sante cohort study. Am J Clin Nutr. 2026 May;123(5):101284. doi: 10.1016/j.ajcnut.2026.101284. Epub 2026 Mar 19.
- Derived from this study: PubMed 41501013Hasenbohler A, Javaux G, Payen de la Garanderie M, Szabo de Edelenyi F, Bourhis L, Agaesse C, De Sa A, Huybrechts I, Pierre F, Coumoul X, Julia C, Kesse-Guyot E, Alles B, Fezeu LK, Hercberg S, Deschasaux-Tanguy M, Cosson E, Tatulashvili S, Chassaing B, Srour B, Touvier M. Associations between preservative food additives and type 2 diabetes incidence in the NutriNet-Sante prospective cohort. Nat Commun. 2026 Jan 7;16(1):11199. doi: 10.1038/s41467-025-67360-w.
- Derived from this study: PubMed 41500678Hasenbohler A, Javaux G, Payen de la Garanderie M, de Edelenyi FS, Yvroud-Hoyos P, Agaesse C, De Sa A, Huybrechts I, Pierre F, Audebert M, Coumoul X, Julia C, Kesse-Guyot E, Alles B, Deschamps V, Hercberg S, Chassaing B, Srour B, Deschasaux-Tanguy M, Touvier M. Intake of food additive preservatives and incidence of cancer: results from the NutriNet-Sante prospective cohort. BMJ. 2026 Jan 7;392:e084917. doi: 10.1136/bmj-2025-084917.
- Derived from this study: PubMed 40992665Cote M, Hutchinson JM, Touvier M, Srour B, Bourhis L, Lamarche B, Fezeu LK. Associations between Dietary Pattern Networks Derived from Machine Learning Algorithms and Cardiovascular Disease Risk in the NutriNet-Sante Cohort. J Nutr. 2025 Nov;155(11):4033-4042. doi: 10.1016/j.tjnut.2025.09.014. Epub 2025 Sep 22.
- Derived from this study: PubMed 40752888Paz-Graniel I, Kose J, Duquenne P, Babio N, Salas-Salvado J, Hercberg S, Galan P, Touvier M, Fezeu LK, Andreeva VA. Alcohol, Smoking, and Their Synergy as Risk Factors for Incident Type 2 Diabetes. Am J Prev Med. 2025 Nov;69(5):108011. doi: 10.1016/j.amepre.2025.108011. Epub 2025 Jul 31.
- Derived from this study: PubMed 40553762Berthy F, Toujgani H, Duquenne P, Fezeu LK, Lairon D, Pointereau P, Touvier M, Hercberg S, Galan P, Alles B, Baudry J, Kesse-Guyot E. Prospective association of the EAT-Lancet reference diet with body weight changes and incidence of overweight and obesity in a French cohort. Am J Clin Nutr. 2025 Aug;122(2):450-459. doi: 10.1016/j.ajcnut.2025.06.013. Epub 2025 Jun 17.
- Derived from this study: PubMed 40514663Toujgani H, Wang J, Perraud E, Baudry J, Berlivet J, Alles B, Fouillet H, Hercberg S, Touvier M, Lairon D, Pointereau P, Couturier C, Mariotti F, Kesse-Guyot E; TRANSFood Consortium. Dietary consumption trajectory profiles over time of French adults from the NutriNet-Sante cohort (2014-2022): multicriteria analysis of sustainability. Int J Behav Nutr Phys Act. 2025 Jun 13;22(1):76. doi: 10.1186/s12966-025-01777-w.
- PubMed abstractLink provided by the sponsor.
- Individual participant dataSharing planned: No
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The Cooking for Health Optimization and Disease Prevention (CHOP) Trial
Cardiovascular Diseases
Recruiting
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Chronic Study
Healthy Participants, Healthy Adult Subject
Not yet recruiting
Nutrition Outcomes Using a Randomized Intervention Via Smartphone on Dietary Habits
Healthy Adult Participants, Mindful Eating Intervention
Recruiting
Satiety, Microbiome, Appetite Regulation, and Tracking Energy Across Targeted Snacks: Acute Postprandial Study
Healthy Participants, Healthy Adult Subject
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Diet, Food, and Nutrition and Exercise, run by University of Paris 13 at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 26 Jul 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mathilde Touvier, Dr (+33148388933, m.touvier@eren.smbh.univ-paris13.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
cancers using health questionnaire and/or the website for declaration of major health events (time frame: every 6 months after registration, up to 10 years of follow-up). The study lists 16 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03335644, which also lists 65 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 26 Jul 2021.