Clinical trials: Diseases Category
Tuberculosis, Pleural Effusion
Efficacy Study of Thrice Weekly Directly Observed Treatment Short-Course Regimen in Tubercular Pleural Effusion
Tubercular pleural effusion is the second most common form of extrapulmonary tuberculosis (EPTB) seen in clinical practice after tuberculosis (TB) lymphadenitis.
- Trial name
- NCT01560078
- Where
- India
- Volunteers
- 360 people
- Sponsor
- All India Institute of Medical Sciences
Thyroid Cancer, Atypia of Undetermined Significance
The Risk Stratification of Papillary Thyroid Cancer With AUS/FLUS by FNA
Purpose: To investigate the clinical characteristics of papillary thyroid cancer (PTC) with Bethesda category III (AUS/FLUS) by fine needle aspiration (FNA) and to assisted the precision treatment.
- Conditions
- Thyroid Cancer, Atypia of Undetermined Significance, FLUS
- Trial name
- NCT04601298
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Shanghai 10th People's Hospital
Breast Cancer
Breast Cancer Biomarker Sample Collection for the dtectDx Assay Verification
The major purpose of this study is to evaluate a laboratory developed test that measures multiple breast cancer-specific biomarker proteins in your blood samples.
- Trial name
- NCT01839045
- Where
- 8 sites in United States
- Volunteers
- 350 people
- Sponsor
- Provista Diagnostics, Inc
CMV
Clinical and Immunological Features of the CMV Infection Atypical Course in Immunocompetent Individuals
Current study evaluates possible correlations between the content of various cell populations, the genetic material of the virus and antibodies to it in the blood of patients and the risk of thrombosis development in patients…
- Trial name
- NCT04392297
- Testing
- Bood leukocyte subsets, CMV specific T-cells, serum CMV IgM / IgG antibodies
- Where
- Belarus
- Volunteers
- 45 people
- Sponsor
- The Republican Research and Practical Center for Epidemiology and Microbiology
Enthesitis-related Arthritis (ERA), Juvenile Psoriatic Arthritis (JPsA)
Long Term Treatment Strategies and Effectiveness of Secukinumab in Patient With JIA Subtypes of JPsA and ERA: Study From German BIKER Registry.
The goal of this study is to understand the long-term treatment strategies in children and adolescents diagnosed with ERA or JPsA who received secukinumab and achieved inactive disease and to evaluate the long-term treatment…
- Trial name
- NCT07190053
- Testing
- Secukinumab
- Volunteers
- 100 people
- Sponsor
- Novartis Pharmaceuticals
Lentigo, Solar Lentigo
Interventional, Monocentric, Double-blind Randomized Category 2b Study Evaluating the Evaluation of the Tolerance of Cyto-selective Difluoroethane-based Cryotherapy in the Treatment of Brown Spots (Solar and Senile Lentigines, Post -Inflammatory Hyperpigmentation (Pih)) on the Face
The goal of this clinical trial is to compare the 2 different prototype of cytoselectivecryotherapy devices (name of the devices : CRYONOVE) use in brown spots on the face of subject from different ethnicities.
- Conditions
- Lentigo, Solar Lentigo, Post Inflammatory Hyperpigmentation
- Trial name
- CS5_10 (NCT06361251)
- Testing
- CRYONOVE (EC14_4osc), CRYONOVE (EC05osc)
- Where
- South Africa
- Volunteers
- 30 people
- Sponsor
- Cryonove Pharma
Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Moderate
Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD
Recruitment of patients with COPD. Assessment of clinical status, determination of vitamin D and cathelicidin levels. In the group with vitamin D deficiency, patients receive cholecalciferol (vitamin D) daily for 3 months.
- Conditions
- Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe
- Trial name
- COPD (NCT05431218)
- Testing
- Cholecalciferol Liquid
- Where
- Kazakhstan
- Volunteers
- 120 people
- Sponsor
- Karaganda Medical University
Pulmonary Tuberculosis
Efficacy of Oral Zinc Administration as an Adjunct Therapy in New Pulmonary Tuberculosis (Category I) Patients
The primary objective of the study is to evaluate the efficacy of oral Zinc administration in new smear positive pulmonary tuberculosis patients.
- Trial name
- NCT00698386
- Testing
- Zinc supplement
- Where
- India
- Volunteers
- 150 people
- Sponsor
- Ministry of Science and Technology, India
Rabies Post-exposure Prophylaxis
Real World Evidence Study of SYN023 in Children Exposed to Rabies
This observational study is an open-label, prospective, multi-center design. The goal is to evaluate the long-term clinical survival outcomes at 3 months and 1 year in individuals under 18 years of age with WHO Category III…
- Trial name
- NCT07327307
- Where
- 6 sites in China
- Volunteers
- 232 people
- Sponsor
- Synermore Biologics (Suzhou) Co., Ltd.
Prevention of TB Recurrence
Study to Check the Efficacy and Safety of Recombinant BCG Vaccine in Prevention of TB Recurrence
This is a Phase II/III trial with two groups of adults successfully cured of category 1 pulmonary TB receiving either VPM1002 or placebo.
- Trial name
- NCT03152903
- Testing
- VPM1002 (Recombinant BCG Vaccine)
- Where
- 10 sites in Bangladesh, India
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Serum Institute of India Pvt. Ltd.
Hypersensitivity, Psychologic Factors in Physical Conditions Classified Elsewhere
Interaction Effect of Asthma and Aeroallergen Category on the Psychological Status in Allergic Rhinitis Patients
Allergic rhinitis (AR) and asthma are considered as "one airway, one disease". Although there is increasing evidence for an association between allergy and depression, it remains unknown if the relationship between AR and asthma…
- Conditions
- Hypersensitivity, Psychologic Factors in Physical Conditions Classified Elsewhere, Respiratory Tract Diseases, Allergic Rhinitis
- Trial name
- NCT01295255
- Volunteers
- 524 people
- Sponsor
- Beijing Tongren Hospital
Ketogenic Diet, Thyroid Function
Dietary Macronutrients and Metabolic Markers
This prospective 12-week dietary intervention study evaluated the effects of a ketogenic diet on thyroid function and glucose-insulin metabolism in premenopausal women aged 30-50 years across different adiposity categories.
- Conditions
- Ketogenic Diet, Thyroid Function, Insulin Resistance, Obesity Overweight
- Trial name
- KETO-THYROID (NCT07775326)
- Testing
- Ketogenic diet
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Breast Cancer
Automated Breast Ultrasound Screening
Women with dense breasts (BIRADS 3 or 4) with a BIRADS category 1 or 2 mammogram are asked to participate in a automated volume breast ultrasound scanner.
- Trial name
- ABUS (NCT02650778)
- Testing
- Breast ultrasound
- Volunteers
- 2,257 people, healthy volunteers welcome
- Sponsor
- Northeastern Ohio Radiology Research and Education Fund
Syntax Score, Appropriateness
Real-time Feedback of SYNTAX Score Category During Coronary Angiographies to Improve Appropriateness of Coronary Revascularization for Patients With Stable Coronary Artery Diseases: a Before-and-after Controlled Study
The SYNTAX score (SS) has been recommended by clinical guideline and appropriate use criteria for coronary revascularization (CR) to provide guidance on optimal treatment strategies for patients with stable coronary artery…
- Conditions
- Syntax Score, Appropriateness, Coronary Revascularization
- Trial name
- NCT03068858
- Testing
- real-time feedback of SYNTAX score category
- Where
- China
- Volunteers
- 3,245 people
- Sponsor
- China National Center for Cardiovascular Diseases
Chronic Obstructive Pulmonary Disease
Phenotypes of COPD in Central and Eastern Europe
The purpose of this study is to assess the representation of COPD patients in terms of categories and phenotypes of the disease in selected countries in Central and Eastern Europe (CEE).
- Trial name
- POPE (NCT02119494)
- Where
- 81 sites in Austria, Bulgaria and 9 more
- Volunteers
- 3,504 people
- Sponsor
- Zuzana Zbožínková, M.Sc.
Rabies, Communicable Disease
A Phase III Clinical Study to Evaluate SYN023's Efficacy and Safety
This is a Phase 3, blinded, randomized study of SYN023 compared to a China licensed Human Rabies Immunoglobulin (a Rabies immune globulin from human sources, HRIG) for the prevention of rabies as part of post-exposure prophylaxis…
- Conditions
- Rabies, Communicable Disease, Virus Diseases, Rhabdoviridae Infections
- Trial name
- NCT04644484
- Testing
- SYN023, Human Rabies Immune Globulin (HRIG), Rabies Vaccine
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Synermore Biologics (Suzhou) Co., Ltd.
Obesity
Responses to Appetite and Taste in the Brain Circuits That Control Eating Behaviour
The aim of this study is to gain insight into brain structure and the neural networks that control taste and eating behaviour in patients with severe obesity undergoing a primary sleeve gastrectomy (SG) or a lifestyle…
- Trial name
- TASTER (NCT03547063)
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University College, London
Neoplasm, Esophagus, Neoplasm, Squamous Cell
Primary Tumor Burden Score:A Novel Staging Parameter for ESCC After nCRT
In this case-only study, the investigators try to define a novel staging parameter, the Primary Tumor Burden Score (PTBS).
- Trial name
- NCT05839002
- Testing
- nCRT
- Volunteers
- 187 people
- Sponsor
- Fudan University
AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL)
A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation
The purpose of this clinical trial is to compare drug combinations to learn which drugs work best to prevent graft-versus-host-disease (GVHD) in people who have received a stem cell transplant.
- Conditions
- AML (Acute Myelogenous Leukemia), Acute Lymphoid Leukemia (ALL), Acute Leukemia (Category), MDS (Myelodysplastic Syndrome)
- Trial name
- ACCELERATE (NCT06859424)
- Testing
- Conditioning Regimen A, Conditioning Regimen B, Conditioning Regimen C
- Where
- 13 sites in United States
- Volunteers
- 358 people
- Sponsor
- Center for International Blood and Marrow Transplant Research
Anemia, Chronic Kidney Disease
20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia
The purpose of this study is to evaluate the hemoglobin response (efficacy), safety, and tolerability of orally administered AKB-6548 in participants with Chronic Kidney Disease (pre-dialysis) with anemia with dosing for 20 weeks.
- Trial name
- NCT01906489
- Testing
- AKB-6548
- Where
- 47 sites in United States
- Volunteers
- 210 people
- Sponsor
- Akebia Therapeutics