Knee InjuriesNCT03641781
Comparison Of Isometric And Isokinetic Strength Training Effects On Physical Performance In Athletes With Knee Pain
A study testing isometric strength training and isokinetic strength training in people with Knee Injuries, run by Isra University.
Trial summary
Frequent sports events causing more injuries in athletes causing decline in their performance. Injuries around knee joint are common. Strength training of hamstring and quadriceps are effective tool in rehabilitation. Read more about this study
- Who is it for?
- Ages 18 to 35 years
- Conditions the study is for
- Knee Injuries
- What is being tested?
- isometric strength training and isokinetic strength training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- No sites listed yet
- Study dates
- Jan 2016to Nov 2016
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 35 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- The adult athletes between ages 18 to 35 years.
- Athletes with unilateral knee pain.
- Both male and female.
Who cannot join
- Athletes with bilateral knee pain and any deformity around knee were excluded from this study.
- Any other joint involvement of lower limb while assessment were also excluded from study.
- Athletes with recent history of surgeries for fractures or ligamentous reconstruction were excluded from this study.
- Patients who were medically unstable.
About this study
Frequent sports events causing more injuries in athletes causing decline in their performance. Injuries around knee joint are common. Strength training of hamstring and quadriceps are effective tool in rehabilitation. The multi-speeds and multi-angles strength training plans were used to see the effects on symptoms and performance in athletes.
Read the detailed description
A total of 69 athletes with knee pain were recruited and randomly divided into two groups. 50 athletes completed the training programs, 25 in each group. Data was also collected from healthy athletes for normative values. International Knee Documentation Committee subjective knee evaluation form was used to report the athlete's knee condition and severity of symptoms including pain. Biodex isokinetic system was used for isokinetic and isometric strength trainings and kinetic data collection. Physical performance of an athlete was assessed by components of fitness through two commonly used tests: Illinois agility run test and vertical jump test. The athletic single leg stability test was used to assess the stability of athletes on Biodex Balance System.
- Conditions
- Knee Injuries
- Being tested
- isometric strength training and isokinetic strength training
- Keywords
- Isokinetic, Isometric, Agility, Athletic Single Leg Stability,, Vertical Jump Biodex, Knee Pain
- Medical subject headings
- Knee Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
isometric strength training and isokinetic strength trainingOther
Isokinetic strength program included strength training at 5 different velocities from slow to fast. Participants were trained on speed of 30°/sec, 90°/sec, 150°/sec, 210°/sec and 270°/sec. Flexion and extension movements were completed with 5 repetitions at each speed.
Participants of isometric strength training group performed isometric contractions at 30°, 45° and 60° of knee flexion with five repetitions at each angle for both hamstring and quadriceps.
| Study group | Role | What they receive |
|---|---|---|
| Isometric strength training group | Active comparator | Knee pain athletes were assessed by The International Knee Documentation Committee (IKDC) 2000 Subjective Knee evaluation form and were assigned into ISOM group. ISOM group participants were involved in isometric strengthTraining at angle of 30°,45°,60° of knee flexion for 5 maximum contraction for both hamstring and quadriceps. 10 sessions were given on alternate day basis by using Biodex Isokinetic system. Receives: Other: isometric strength training and isokinetic strength training |
| Isokinetic strength training group | Active comparator | Knee pain athletes were assessed by The International Knee Documentation Committee (IKDC) 2000 Subjective Knee evaluation form and were assigned into ISOK group isokinetic training group randomly. ISOk group participants were involved in Training at speed of 30 deg/sec, 90deg/sec, 150/deg/sec 210deg/sec, 270deg/sec 5 repetition for both hamstring and quadriceps. 10 sessions were given on alternate day basis by using Biodex Isokinetic system. Receives: Other: isometric strength training and isokinetic strength training |
| Healthy control group | No intervention | Data for outcome parameters including Peak torque average peak torque average power agonist antagonist ratio by using biodex isokinetic system for both by isometric contraction method and isokinetic method. For performance test were recorded for healthy control of same age group to compare the training effect with healthy control values. |
What is being measured
The primary outcome is the main question the study is designed to answer.
change in Agility Run Test time
The agility run test was conducted by placing cones at the non-slippery surface. The time to complete the test was recorded by using stop watch. A 10 Meter distance in figure of 8 was made on ground with help of cones. Time taken to complete was recorded in seconds.
Measured: change from baseline through completion an average of 3 weeks
change in Vertical Jump test height
Vertical jump test was conducted by using the measuring tape placed on wall. Athletes were standing along the wall and the standing height, the highest level of finger touching the wall was recorded initially. Athlete then jumped vertically and marked on the wall and performed three repetitions. The greatest difference between initial standing height and after jump height was recorded as score of vertical jump.
Measured: change from baseline through completion an average of 3 weeks
change in Athletic single leg stability test
The athletic single leg stability test was used to assess the stability of athlete conducted by using Biodex Balance System SD (Biodex Medical Systems, Inc. NY, USA). Athletes were standing on involved leg and platform setting was at level 4. Athletes performed 3 repetitions of 20 seconds each with 10 seconds rest between the repetitions to complete the test. Overall stability index, anterior posterior index, and medial lateral index were recorded.
Measured: change from baseline through completion an average of 3 weeks
Secondary outcomes (1)
change in Peak Torque value (FT-LB)
Highest muscular force output at any moment during a repetition. Peak torque indicates the muscle's maximum strength capability. This is also equivalent to a 1-repetition maximum (RM) isotonic strength test.
Measured: change from baseline through completion an average of 3 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Aug 2018
- Study startJan 2016
- Primary completionSep 2016
- Study completionNov 2016
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee InjuriesStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Athletes were randomly assigned into two groups: Isometric (ISOM) and Isokinetic (ISOK). A coin was flipped at start of data collection for the first patient to be assigned odd number and included in isometric group. Later on odd and even numbered patients were included in specific group. Additionally, data was collected from healthy athletes doing their training at Pakistan Sports Board, called healthy control group. Due to ethical constraints knee pain athletes were not included as control subjects
- Masking
- None (open label)
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Isra University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hafiz Muhammad Manan Haider Khan, Isra University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03641781
- Sponsor's protocol ID
- IIRS-IUISB/PHD/006
- Status last verified
- Aug 2018
- First submitted
- 15 Aug 2018
- Last updated
- 22 Aug 2018
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 22 Aug 2018. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison Of Isometric And Isokinetic Strength Training Effects On Physical Performance In Athletes With Knee Pain
- ClinicalTrials.gov ID
- NCT03641781
- Acronym / sponsor ID
- IIRS-IUISB/PHD/006
- Conditions
- Knee Injuries
- Keywords
- Isokinetic, Isometric, Agility, Athletic Single Leg Stability,, Vertical Jump Biodex, Knee Pain
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Isra UniversityUniversity, hospital or other
- Study start
- Jan 2016 (actual)
- Primary completion
- Sep 2016 (actual)
- Study completion
- Nov 2016 (actual)
- First posted
- 22 Aug 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Frequent sports events causing more injuries in athletes causing decline in their performance. Injuries around knee joint are common. Strength training of hamstring and quadriceps are effective tool in rehabilitation. The multi-speeds and multi-angles strength training plans were used to see the effects on symptoms and performance in athletes.
Detailed description
A total of 69 athletes with knee pain were recruited and randomly divided into two groups. 50 athletes completed the training programs, 25 in each group. Data was also collected from healthy athletes for normative values. International Knee Documentation Committee subjective knee evaluation form was used to report the athlete's knee condition and severity of symptoms including pain. Biodex isokinetic system was used for isokinetic and isometric strength trainings and kinetic data collection. Physical performance of an athlete was assessed by components of fitness through two commonly used tests: Illinois agility run test and vertical jump test. The athletic single leg stability test was used to assess the stability of athletes on Biodex Balance System.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- Athletes were randomly assigned into two groups: Isometric (ISOM) and Isokinetic (ISOK). A coin was flipped at start of data collection for the first patient to be assigned odd number and included in isometric group. Later on odd and even numbered patients were included in specific group. Additionally, data was collected from healthy athletes doing their training at Pakistan Sports Board, called healthy control group. Due to ethical constraints knee pain athletes were not included as control subjects
| Arm | Type | Receives |
|---|---|---|
| Isometric strength training group | Active comparator | Other: isometric strength training and isokinetic strength trainingKnee pain athletes were assessed by The International Knee Documentation Committee (IKDC) 2000 Subjective Knee evaluation form and were assigned into ISOM group. ISOM group participants were involved in isometric strengthTraining at angle of 30°,45°,60° of knee flexion for 5 maximum contraction for both hamstring and quadriceps. 10 sessions were given on alternate day basis by using Biodex Isokinetic system. |
| Isokinetic strength training group | Active comparator | Other: isometric strength training and isokinetic strength trainingKnee pain athletes were assessed by The International Knee Documentation Committee (IKDC) 2000 Subjective Knee evaluation form and were assigned into ISOK group isokinetic training group randomly. ISOk group participants were involved in Training at speed of 30 deg/sec, 90deg/sec, 150/deg/sec 210deg/sec, 270deg/sec 5 repetition for both hamstring and quadriceps. 10 sessions were given on alternate day basis by using Biodex Isokinetic system. |
| Healthy control group | No intervention | –Data for outcome parameters including Peak torque average peak torque average power agonist antagonist ratio by using biodex isokinetic system for both by isometric contraction method and isokinetic method. For performance test were recorded for healthy control of same age group to compare the training effect with healthy control values. |
Who may qualify
- Ages
- 18 to 35 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- The adult athletes between ages 18 to 35 years.
- Athletes with unilateral knee pain.
- Both male and female.
Key exclusion criteria (4 listed)
- Athletes with bilateral knee pain and any deformity around knee were excluded from this study.
- Any other joint involvement of lower limb while assessment were also excluded from study.
- Athletes with recent history of surgeries for fractures or ligamentous reconstruction were excluded from this study.
- Patients who were medically unstable.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| isometric strength training and isokinetic strength trainingIsokinetic strength program included strength training at 5 different velocities from slow to fast. Participants were trained on speed of 30°/sec, 90°/sec, 150°/sec, 210°/sec and 270°/sec. Flexion and extension movements were completed with 5 repetitions at each speed. Participants of isometric strength training group performed isometric contractions at 30°, 45° and 60° of knee flexion with five repetitions at each angle for both hamstring and quadriceps. | Other | Isokinetic strength training group, Isometric strength training group |
Primary outcome
change in Agility Run Test time
Time frame: change from baseline through completion an average of 3 weeks
The agility run test was conducted by placing cones at the non-slippery surface. The time to complete the test was recorded by using stop watch. A 10 Meter distance in figure of 8 was made on ground with help of cones. Time taken to complete was recorded in seconds.
change in Vertical Jump test height
Time frame: change from baseline through completion an average of 3 weeks
Vertical jump test was conducted by using the measuring tape placed on wall. Athletes were standing along the wall and the standing height, the highest level of finger touching the wall was recorded initially. Athlete then jumped vertically and marked on the wall and performed three repetitions. The greatest difference between initial standing height and after jump height was recorded as score of vertical jump.
change in Athletic single leg stability test
Time frame: change from baseline through completion an average of 3 weeks
The athletic single leg stability test was used to assess the stability of athlete conducted by using Biodex Balance System SD (Biodex Medical Systems, Inc. NY, USA). Athletes were standing on involved leg and platform setting was at level 4. Athletes performed 3 repetitions of 20 seconds each with 10 seconds rest between the repetitions to complete the test. Overall stability index, anterior posterior index, and medial lateral index were recorded.
1 secondary outcome
change in Peak Torque value (FT-LB)
Time frame: change from baseline through completion an average of 3 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Aug 2018.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
A study testing isometric strength training and isokinetic strength training in people with Knee Injuries, run by Isra University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Aug 2018. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
change in Agility Run Test time (time frame: change from baseline through completion an average of 3 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Aug 2018.