Critical CareMOBDBNCT03666286
Prospective Registry of Mobilization-, Routine- and Outcome Data of Intensive Care Patients
An observational study of Critical Care and Rehabilitation, run by Technical University of Munich at 1 site in Germany.
Trial summary
Registry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Critical Care, Rehabilitation, Outcome Assessment (Health Care)
- How many people
- 1,172 participants
- Where
- 1 siteGermany
- Study dates
- 1 Feb 2017to 22 Nov 2022
- How long will I take part?
- 12 Months
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Child, Adult, Older adult
Study population: Intensive Care Unit Patients
Who may be able to join
- Intensive care unit stay > 24 hours
Who cannot join
- -
Trial locations and contacts
1 site in 1 country.
About this study
Registry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments.
Read the detailed description
Registry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments.
The database is supposed to help quality improvement as well as
- Keywords
- early mobilization, intensive care, longterm outcomes
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Intensive Care Patients | Patients >24h on intensive care |
What is being measured
The primary outcome is the main question the study is designed to answer.
Physical Function at hospital discharge
Physical function at ICU discharge with either the mmFIM (minimal modified Functional Independence Measure) or the Barthel subdomains transfer, locomotion and climbing stairs
Measured: At hospital discharge, on average within 1 month
Secondary outcomes (10)
Hospital Mortality
Hospital Mortality
Measured: At hospital discharge, on average within 1 month
Pre-ICU Function
Pre-ICU Function assessed with the WHODAS 2.0 (World Health Organisation's Disability Assessment Schedule), EQ5D (European Quality of Life 5 Dimensions 5 Level) and work details
Measured: 2 weeks before ICU admission
Global function of the patient
Global function of the patient assessed with the WHODAS 2.0 (World Health Organisation's Disability Assessment Schedule)
Measured: 180 and 360 days after ICU discharge
Physical function of the patient
Physical function of the patient assessed with the IADL (The Lawton Instrumental Activities of Daily Living)
Measured: 180 and 360 days after ICU discharge
Quality of Life of the patient
Quality of Life of the patient assessed with the EQ5D (European Quality of Life 5 Dimensions 5 Level)
Measured: 180 and 360 days after ICU discharge
Cognitive Function
Cognitive Function assessed with the MoCA blind (Montreal Cognitive Assessment)
Measured: 180 and 360 days after ICU discharge
Anxiety and Depression
Anxiety and Depression assessed with the IES-R (Impact of Event Scale - Revised) and HADS (Hospital Anxiety and Depression scale)
Measured: 180 and 360 days after ICU discharge
Return to work
Return to work assessed with the WHODAS 2.0 (World Health Organisation's Disability Assessment Schedule)
Measured: 180 and 360 days after ICU discharge
ICU Mortality
ICU Mortality
Measured: At ICU Discharge, on average within 2 weeks
Physical function at ICU discharge
Physical function at ICU discharge with either the mmFIM (minimal modified Functional Independence Measure) or the Barthel subdomains transfer, locomotion and climbing stairs
Measured: At ICU Discharge, on average within 2 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 Sep 2018
- Study start1 Feb 2017
- Primary completion30 Apr 2019
- Study completion22 Nov 2022
Why it stopped: No further funding to keep up registry.
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Critical CareStudies of the same condition, open and under way.
- More trials run by Technical University of MunichThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,172 participants (actual)
- Target duration
- 12 Months
Sponsor and investigators
- Lead sponsor
- Technical University of Munich
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Prof. Dr. Stefan Schaller, MD, Technical University of Munich
- Investigators
- Stefan J Schaller, MD, Principal investigator, Technical University of Munich
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03666286
- Sponsor's protocol ID
- MOBDB
- Other IDs
- DRKS00011576
- Acronym
- MOBDB
- Status last verified
- Sep 2025
- First submitted
- 4 Sep 2018
- Last updated
- 19 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: Sharing of anonymous data might be possible on reasonable scientific request.
Publications
Lorenz M, Fuest K, Ulm B, Grunow JJ, Warner L, Bald A, Arsene V, Verfuss M, Daum N, Blobner M, Schaller SJ. The optimal dose of mobilisation therapy in the ICU: a prospective cohort study. J Intensive Care. 2023 Nov 20;11(1):56. doi: 10.1186/s40560-023-00703-1.
PubMed 37986100Fuest KE, Ulm B, Daum N, Lindholz M, Lorenz M, Blobner K, Langer N, Hodgson C, Herridge M, Blobner M, Schaller SJ. Clustering of critically ill patients using an individualized learning approach enables dose optimization of mobilization in the ICU. Crit Care. 2023 Jan 3;27(1):1. doi: 10.1186/s13054-022-04291-8.
PubMed 36597110
Study at a glance
From the registry record, last updated by the sponsor on 19 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prospective Registry of Mobilization-, Routine- and Outcome Data of Intensive Care Patients
- ClinicalTrials.gov ID
- NCT03666286
- Acronym / sponsor ID
- MOBDB / MOBDB
- Keywords
- early mobilization, intensive care, longterm outcomes
- Study type
- Observational
- Recruitment status
- TerminatedReason stopped: No further funding to keep up registry.
- Enrolment
- 1,172 participants (actual)
- Lead sponsor
- Technical University of MunichUniversity, hospital or other
- Study start
- 1 Feb 2017 (actual)
- Primary completion
- 30 Apr 2019 (actual)
- Study completion
- 22 Nov 2022 (actual)
- First posted
- 11 Sep 2018 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Registry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments.
Detailed description
Registry database of intensive care patients. These data comprises of routine data including mobilization data and follow up assessments.
The database is supposed to help quality improvement as well as
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 12 Months
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Intensive Care Patients | – | –Patients >24h on intensive care |
Who may qualify
- Sex
- All
- Age groups
- Child, Adult, Older adult
- Study population
- Intensive Care Unit Patients
Key inclusion criteria (1 listed)
- Intensive care unit stay > 24 hours
Key exclusion criteria (1 listed)
- -
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Physical Function at hospital discharge
Time frame: At hospital discharge, on average within 1 month
Physical function at ICU discharge with either the mmFIM (minimal modified Functional Independence Measure) or the Barthel subdomains transfer, locomotion and climbing stairs
10 secondary outcomes
Hospital Mortality
Time frame: At hospital discharge, on average within 1 month
Pre-ICU Function
Time frame: 2 weeks before ICU admission
Global function of the patient
Time frame: 180 and 360 days after ICU discharge
Physical function of the patient
Time frame: 180 and 360 days after ICU discharge
Quality of Life of the patient
Time frame: 180 and 360 days after ICU discharge
Cognitive Function
Time frame: 180 and 360 days after ICU discharge
Anxiety and Depression
Time frame: 180 and 360 days after ICU discharge
Return to work
Time frame: 180 and 360 days after ICU discharge
ICU Mortality
Time frame: At ICU Discharge, on average within 2 weeks
Physical function at ICU discharge
Time frame: At ICU Discharge, on average within 2 weeks
Results and safety
The study was stopped early (reason given: No further funding to keep up registry.). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Sep 2025.
- Derived from this study: PubMed 37986100Lorenz M, Fuest K, Ulm B, Grunow JJ, Warner L, Bald A, Arsene V, Verfuss M, Daum N, Blobner M, Schaller SJ. The optimal dose of mobilisation therapy in the ICU: a prospective cohort study. J Intensive Care. 2023 Nov 20;11(1):56. doi: 10.1186/s40560-023-00703-1.
- Derived from this study: PubMed 36597110Fuest KE, Ulm B, Daum N, Lindholz M, Lorenz M, Blobner K, Langer N, Hodgson C, Herridge M, Blobner M, Schaller SJ. Clustering of critically ill patients using an individualized learning approach enables dose optimization of mobilization in the ICU. Crit Care. 2023 Jan 3;27(1):1. doi: 10.1186/s13054-022-04291-8.
- Individual participant dataSharing planned: Undecided. Sharing of anonymous data might be possible on reasonable scientific request.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Stefan J Schaller, MD principal investigator
Technical University of Munich
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Critical Care and Rehabilitation, run by Technical University of Munich at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 19 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: No further funding to keep up registry.). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Physical Function at hospital discharge (time frame: At hospital discharge, on average within 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03666286, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Sep 2025.