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Cochlear ImplantsPitch_TrainNCT03707691

Pitch Perception and Memory: Deficits and Training

A study testing Listening tests. Pitch training protocol, visuo-spatial training protocol and EEG/MEG/MRI recordings. in people with Cochlear Implants, run by Hospices Civils de Lyon at 1 site in France.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

Pitch perception and memory are central in auditory cognition, in particular for sound source segregation and recognition, speech prosody and music processing. Here the investigator assess pitch perception and memory in hearing-impaired listeners wearing cochlear implant(s) and listeners with congenital amusia, both… Read more about this study

Who is it for?
Ages 5 to 90 yearsHealthy volunteers can take part
Conditions the study is for
Cochlear Implants
What is being tested?
Listening tests. Pitch training protocol, visuo-spatial training protocol and EEG/MEG/MRI recordings.
Could I receive a placebo?
No, everyone receives an active treatment
How many people
960 participants
Where
1 siteFrance
Study dates
26 Nov 2019to 26 Nov 2029
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 5 to 90 years
  • All sexes
  • Healthy volunteers accepted
  • Child, Adult, Older adult

Who may be able to join

  • For adult participants:
  • Aged between 18 and 90
  • Absence of neurological and psychiatric disorders
  • No major cognitive deficit, ability to understand and apply study instructions
  • Motivation to participate efficiently in the study
  • Written informed consent to participant in the study
Show all 15Show fewer
  • Affiliated to social security
  • Control participants and participants with congenital amusia for Experiment 5: MRI/MEG compatibility
  • For underage participants:
  • Subject aged 5 years and over
  • Informed consent of parents or guardians for the participation of the child being studied
  • No neurological or psychiatric history
  • Without major cognitive impairment and ability to understand and apply setpoint.
  • Subject affiliated to a social security scheme
  • Motivation to participate effectively in the project

Who cannot join

  • For adult participants:
  • Age below 18 or above 90
  • Pregnant or breast-feeding woman
  • For underage participants:
  • Pregnant or nursing minors

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Anne CACLIN contact

4 72 13 89 04 ext. +33

anne.caclin@inserm.fr

Barbara Tillmann contact

4 37 28 74 89 ext. +33

barbara.tillmann@cnrs.fr

France1 site, 1 recruiting

  • Lyon Neuroscience Research Center

    Bron, 69500

    Anne CACLIN, PhD, 4 72 13 89 04 ext. +33, anne.caclin@inserm.fr

    Barbara Tillmann, PhD, 4 37 28 74 89 ext. +33, barbara.tillmann@cnrs.fr

    Recruiting

Other trials in France

About this study

Pitch perception and memory are central in auditory cognition, in particular for sound source segregation and recognition, speech prosody and music processing. Here the investigator assess pitch perception and memory in hearing-impaired listeners wearing cochlear implant(s) and listeners with congenital amusia, both compared with control listeners. Behavioral, EEG, and MEG measures are collected in audio and audio-visual contexts to characterize pitch processing deficits, and test a pitch training program.

Being tested
Listening tests. Pitch training protocol, visuo-spatial training protocol, EEG/MEG/MRI recordings.
Keywords
Hearing, Cochlear Implants, Congenital Amusia, Pitch, Audio-visual interactions
Medical subject headings
Tune Deafness

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Listening tests. Pitch training protocolBehavioural

    The two training protocols consists of perceptual tasks (auditory or visual exercises) performed repetitively using a tablet. Each protocol consists in 30 sessions of ~20 minutes performed at home over a period of 15 weeks.

  • visuo-spatial training protocolBehavioural

    The two training protocols consists of perceptual tasks (auditory or visual exercises) performed repetitively using a tablet. Each protocol consists in 30 sessions of ~20 minutes performed at home over a period of 15 weeks.

  • EEG/MEG/MRI recordings.Behavioural

    Listening tests. EEG/MEG/MRI recordings

Study groups in NCT03707691
Study groupRoleWhat they receive
Cochlear implant usersExperimentalIn both arms a pitch training protocol and a visuo-spatial training protocol are applied.
Receives: Behavioral: Listening tests. Pitch training protocol; Behavioral: visuo-spatial training protocol; Behavioral: EEG/MEG/MRI recordings.
Participants with Congenital AmusiaExperimentalIn both arms a pitch training protocol and a visuo-spatial training protocol are applied.
Receives: Behavioral: Listening tests. Pitch training protocol; Behavioral: visuo-spatial training protocol; Behavioral: EEG/MEG/MRI recordings.
Control ParticipantsExperimentalNot described
Receives: Behavioral: Listening tests. Pitch training protocol; Behavioral: visuo-spatial training protocol; Behavioral: EEG/MEG/MRI recordings.

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. percentages of correct responses in listening tests

    Measured: during procedure

  2. reaction times in listening tests

    Measured: during procedure

  3. Event-Related Fields

    MEG measurements

    Measured: during procedure

  4. Oscillations

    MEG measurements

    Measured: during procedure

Secondary outcomes (6)

  1. percentages of correct responses

    Performance in listening tests in audio contexts

    Measured: Day 0

  2. percentages of correct responses

    Performance in listening tests in audio-visual contexts

    Measured: Day 0

  3. reaction times

    Performance in listening tests in audio contexts

    Measured: Day 0

  4. reaction times

    Performance in listening tests in audio-visual contexts

    Measured: Day 0

  5. Event-Related Fields

    EEG measurements

    Measured: Day 0

  6. Oscillations

    EEG measurements

    Measured: Day 0

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted16 Oct 2018
  2. Study start26 Nov 2019
  3. Primary completion26 Nov 2029 (estimated)
  4. Study completion26 Nov 2029 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Basic science
Allocation
Randomised
Intervention model
Crossover
Masking
None (open label)
Enrolment
960 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT03707691
Sponsor's protocol ID
69HCL18_0632
Other IDs
2018-A02670-55
Acronym
Pitch_Train
Status last verified
Oct 2026
First submitted
12 Oct 2018
Last updated
22 Oct 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Questions about this trial

What is this clinical trial studying?

A study testing Listening tests. Pitch training protocol, visuo-spatial training protocol and EEG/MEG/MRI recordings. in people with Cochlear Implants, run by Hospices Civils de Lyon at 1 site in France.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 15 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 22 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Anne CACLIN (4 72 13 89 04 ext. +33, anne.caclin@inserm.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

percentages of correct responses in listening tests (time frame: during procedure). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT03707691.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Oct 2026.

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