Osteoarthritis, KneeNCT03737149
A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
A study testing mymobility with Apple Watch in people with Osteoarthritis, Knee and Osteoarthritis, Hip, run by Zimmer Biomet at 30 sites in 4 countries.
Trial summary
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a viable (and potentially improved) alternative to current standard of care physical therapy… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Osteoarthritis, Knee, Osteoarthritis, Hip
- What is being tested?
- mymobility with Apple Watch
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 6,559 participants
- Where
- 30 sitesin 4 countries
- Study dates
- 22 Oct 2018to 15 Apr 2025
- Phase
- Interventional
- Are there results?
- Yes, posted in the registrySummary in the doctors' view
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Subject must be 18 years of age or older.
- Subject qualifies for a primary, unilateral total or partial knee arthroplasty, based on physical exam and medical history.
- Investigator plans to treat subject with a commercially-available device, used on-label according to the manufacturer's instructions for use, as part of their clinical care.
- Subject owns and maintains an iPhone capable of pairing to the Apple Watch, supporting iOS updates and is compatible with the mymobility App.
- Subject is willing and able to complete the protocol required follow-up.
- Subject is able to read and understand the language used in the mymobility App for their region.
- Subject is willing and able to provide written Informed Consent and Authorization by signing and dating the IRB/EC approved Informed Consent Form and Authorization. Where applicable, subject must also be willing to provide authorization for use of protected health information in accordance with local privacy laws.
- Subject is mobile with no more than a single cane/single crutch assist preoperatively.
Who cannot join
- Subject is a current alcohol or drug abuser as defined by the investigator.
- Subject is considered a member of a protected population (e.g., prisoner, mentally incompetent, etc.).
- Subject has systemic inflammatory arthropathies which would interfere or compromise the activity profiles within this study.
- Subject is currently participating in any other surgical intervention, physical therapy or pain management study which would compromise the results of this study.
- Subject requires simultaneous or staged bilateral replacements, staged<90 days apart. Subjects can be enrolled into the study for the second, staged arthroplasty if scheduled >89 days after their first, contralateral replacement.
Trial locations and contacts
30 sites in 4 countries.
30 sites in 4 countries
United States26 sites
New Mexico Orthopaedic Associates
Albuquerque, New Mexico, 87110
Emory University
Atlanta, Georgia, 30329
OrthoBethesda
Bethesda, Maryland, 20817
Rothman Institute
Bryn Mawr, Pennsylvania, 19010
Rush University Medical Center
Chicago, Illinois, 60612
Cleveland Clinic Main Campus
Cleveland, Ohio, 44195
Colorado Joint Replacement
Denver, Colorado, 80210
Sah Orthopaedic Associates
Fremont, California, 94538
Panorama Orthopedics & Spine Center
Golden, Colorado, 80401
Midwest Center for Joint Replacement
Indianapolis, Indiana, 46241
Hoag Orthopedic Institute
Irvine, California, 92618
Bluegrass Orthopaedics
Lexington, Kentucky, 40509
Rothman Institute
Montvale, New Jersey, 07645
Duke University
Morrisville, North Carolina, 27560
JIS Orthopedics
New Albany, Ohio, 43054
Newton-Wellesley Hospital
Newton, Massachusetts, 02462
University of Pennsylvania
Philadelphia, Pennsylvania, 19104
Orthopedic + Fracture Specialists
Portland, Oregon, 97225
Stanford University
Redwood City, California, 94063
Ascension Medical Group - University Orthopaedic Specialists
Rochester Hills, Michigan, 48307
University of Utah
Salt Lake City, Utah, 84108
Washington University
St Louis, Missouri, 63110
Foundation for Orthopedic Research and Education
Temple Terrace, Florida, 33637
Michigan Orthopaedic Surgeons
Troy, Michigan, 48084
ROC Orthopedics
Tualatin, Oregon, 97062
Cleveland Clinic Florida
Weston, Florida, 33331
Australia2 sites
National Capital Private Hospital
Canberra, Australian Capital Territory, 2605
Epworth Healthcare - Richmond
Richmond, Victoria, 3121
About this study
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a viable (and potentially improved) alternative to current standard of care physical therapy for hip and knee arthroplasty.
Read the detailed description
This is a post-market prospective, multi-center longitudinal study in subjects undergoing primary total knee arthroplasty (TKA), total hip arthroplasty (THA), or partial knee arthroplasty (PKA). The study objective is to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a viable (and potentially improved) alternative to current standard of care patient education and physical therapy for hip and knee arthroplasty. The study will be conducted in phases. The first phase (N = 300) will consist of a pilot cohort of subjects and will primarily serve to determine site study staffing needs and time required for various elements of study execution. The second phase (N = 1,000, RCT) will consist of a randomized controlled subject cohort and will compare outcomes of mobile application-guided exercises and activity with standard of care (SOC) physical therapy. The third phase (N ~ 10,000 including subjects from both Phase I and the study arm from RCT/Phase II) will seek to collect enough data to enable the creation of decision support algorithms for outcomes of joint replacement. All subjects will undergo a TKA, THA, or PKA using SOC procedures and commercially-available devices as part of their clinical care. Subjects will then complete prescribed post-operative activities, such as physical therapy, according to SOC or performing exercises as scheduled through the mymobility app. In office assessments will be conducted at approximately 30 days prior to surgery, 30 days after surgery, and 3 months after surgery. Virtual assessments (including subject questionnaires and recording of adverse events) will occur at approximately 6 months and 1 year post-op.
February 2022 update: Eligibility criteria for new patients includes total knee and partial knee arthroplasty surgeries. Previously enrolled total hip arthroplasty patients will remain in the study for follow-up.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip
- Being tested
- mymobility with Apple Watch
- Keywords
- Knee Replacement, Knee Arthroplasty, Hip Replacement, Hip Arthroplasty, Joint Replacement, Physical Therapy, Partial Knee Replacement, Hip Pain, Chronic, Knee Pain, Chronic
- Medical subject headings
- Osteoarthritis, Knee, Osteoarthritis, Hip, Bronchiolitis Obliterans Syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
mymobility with Apple WatchOther
The mymobility mobile application is a mobile software platform designed to facilitate remote episode of care management and asynchronous communication between the provider care team and their patient via provider-approved care plans and engagement communications. Current care pathways have been developed for: Total Hip Replacement, Total Knee Replacement and Partial Knee Replacement. Designed for the orthopedic population, mymobility also integrates wearable data from the Apple Watch into provider dashboards, providing enhanced understanding and monitoring of patients throughout the episode of care.
| Study group | Role | What they receive |
|---|---|---|
| mymobility with Apple Watch | Experimental | Post-operative mobile application-guided education and exercise paired with accurate and sensitive activity monitoring. Receives: Other: mymobility with Apple Watch |
| Standard of Care Physical Therapy | No intervention | Standard of care patient education and post-operative physical therapy, as determined by local site guidelines and care pathways. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Phase II (RCT): Readmissions
The number of subjects with a readmission within 30 days after knee or hip replacement surgery.
Measured: 30 Days
Secondary outcomes (12)
Phase II (RCT): Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS, JR)
The KOOS, JR score ranges from 0 to 100 where 0 represents total knee disability and 100 represents perfect knee health.
Measured: 90 Days
Phase II (RCT): Hip Disability and Osteoarthritis Outcome Score - Joint Replacement (HOOS, JR)
The HOOS, JR score ranges from 0 to 100 where 0 represents total hip disability and 100 represents perfect hip health.
Measured: 90 Days
Phase II RCT: EQ-5D-5L
The EQ-5D is a standardized instrument widely used to measure health status. It is a self-reported assessment of the participant's quality of life. The score ranges from a minimum score of -0.573 to a maximum score of 1, with higher scores indicating higher health utility. Negative numbers correspond to a self-assessed health state worse than being dead.
Measured: 90 Days
Phase II (RCT): Manipulation Under Anesthesia (MUA)
The number of subjects with a manipulation under anesthesia (MUA) within 90 days after knee replacement surgery.
Measured: 90 Days
Phase II (RCT): Timed Up and Go (TUG)
Timed Up and Go Test: The time to rise from a chair, walk 10 feet, turn around, walk back to the chair and sit down.
Measured: 90 Days
Phase II (RCT): Single-Leg Stance (SLS) Test
Balance Test while standing on a single leg. Three tests are performed and the best of the three times is recorded. The maximum time for this test is 60 seconds.
Measured: 90 Days
Phase II (RCT): Subject Satisfaction
Comparison of subject satisfaction survey results between the study groups.
The Knee Society Scoring System (KSS) satisfaction score ranges from 0 to 40, with higher scores indicating greater satisfaction.
Measured: 90 Days
Phase II RCT: Urgent Care Center and Emergency Room Visits
The number of subjects with urgent care visits or emergency room visits within 90 days after knee or hip replacement surgery.
Measured: 90 Days
Phase I (Pilot): Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS, JR)
The KOOS, JR score ranges from 0 to 100 where 0 represents total knee disability and 100 represents perfect knee health.
Measured: 90 Days
Phase I (Pilot): Hip Disability and Osteoarthritis Outcome Score - Joint Replacement (HOOS, JR)
The HOOS, JR score ranges from 0 to 100 where 0 represents total hip disability and 100 represents perfect hip health.
Measured: 90 Days
Phase III (Correlative): Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS, JR)
The KOOS, JR score ranges from 0 to 100 where 0 represents total knee disability and 100 represents perfect knee health.
Measured: 90 Days
Phase III (Correlative): Hip Disability and Osteoarthritis Outcome Score - Joint Replacement (HOOS, JR)
The HOOS, JR score ranges from 0 to 100 where 0 represents total hip disability and 100 represents perfect hip health.
Measured: 90 Days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Nov 2018
- Study start22 Oct 2018
- Primary completion15 Apr 2025
- Study completion15 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
- Publications (37)Papers the sponsor has linked to this study.
- Other trials for Osteoarthritis, KneeStudies of the same condition, open and under way.
- More trials run by Zimmer BiometThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- This is a staged cohort study. In the first (pilot) cohort, all participating subjects will utilize the mymobility with Apple Watch platform. In the second (RCT) cohort, approximately 1,000 subjects will be randomized 1:1 to either the mymobility with Apple Watch platform or standard of care SOC. In the third (correlative analytics) cohort, all participating subjects will utilize the mymobility with Apple Watch platform.
- Masking
- None (open label)
- Enrolment
- 6,559 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zimmer Biomet
- Sponsor type
- Industry (pharma, biotech, devices)
- Responsible party
- Sponsor
- Investigators
- Hillary Overholser, Study director, Zimmer Biomet
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT03737149
- Sponsor's protocol ID
- CLU2018-13CH
- Status last verified
- Mar 2026
- First submitted
- 26 Oct 2018
- Last updated
- 23 Mar 2026
- Results posted
- Yes, on ClinicalTrials.gov
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Crawford DA, Duwelius PJ, Sneller MA, Morris MJ, Hurst JM, Berend KR, Lombardi AV. 2021 Mark Coventry Award: Use of a smartphone-based care platform after primary partial and total knee arthroplasty: a prospective randomized controlled trial. Bone Joint J. 2021 Jun;103-B(6 Supple A):3-12. doi: 10.1302/0301-620X.103B6.BJJ-2020-2352.R1.
PubMed 34053272Crawford DA, Lombardi AV Jr, Berend KR, Huddleston JI 3rd, Peters CL, DeHaan A, Zimmerman EK, Duwelius PJ. Early outcomes of primary total hip arthroplasty with use of a smartphone-based care platform: a prospective randomized controlled trial. Bone Joint J. 2021 Jul;103-B(7 Supple B):91-97. doi: 10.1302/0301-620X.103B7.BJJ-2020-2402.R1.
PubMed 34192907Tripuraneni KR, Foran JRH, Munson NR, Racca NE, Carothers JT. A Smartwatch Paired With A Mobile Application Provides Postoperative Self-Directed Rehabilitation Without Compromising Total Knee Arthroplasty Outcomes: A Randomized Controlled Trial. J Arthroplasty. 2021 Dec;36(12):3888-3893. doi: 10.1016/j.arth.2021.08.007. Epub 2021 Aug 9.
PubMed 34462184Alexander JS, Redfern RE, Duwelius PJ, Berend KR, Lombardi AV Jr, Crawford DA. Use of a Smartphone-Based Care Platform After Primary Partial and Total Knee Arthroplasty: 1-Year Follow-Up of a Prospective Randomized Controlled Trial. J Arthroplasty. 2023 Jul;38(7 Suppl 2):S208-S214. doi: 10.1016/j.arth.2023.02.082. Epub 2023 Mar 6.
PubMed 36889524Christensen JC, Blackburn BE, Anderson LA, Gililland JM, Peters CL, Archibeck MJ, Pelt CE. Recovery Curve for Patient Reported Outcomes and Objective Physical Activity After Primary Total Knee Arthroplasty-A Multicenter Study Using Wearable Technology. J Arthroplasty. 2023 Jun;38(6S):S94-S102. doi: 10.1016/j.arth.2023.03.060. Epub 2023 Mar 28.
PubMed 36996947Sato EH, Stevenson KL, Blackburn BE, Peters CL, Archibeck MJ, Pelt CE, Gililland JM, Anderson LA. Recovery Curves for Patient Reported Outcomes and Physical Function After Total Hip Arthroplasty. J Arthroplasty. 2023 Jul;38(7S):S65-S71. doi: 10.1016/j.arth.2023.04.012. Epub 2023 Apr 15.
PubMed 37068568Booth MW, Riegler V, King JS, Barrack RL, Hannon CP. Patients' Perceptions of Remote Monitoring and App-Based Rehabilitation Programs: A Comparison of Total Hip and Knee Arthroplasty. J Arthroplasty. 2023 Jul;38(7S):S39-S43. doi: 10.1016/j.arth.2023.04.032. Epub 2023 Apr 23.
PubMed 37088222Fary C, Cholewa J, Abshagen S, Van Andel D, Ren A, Anderson MB, Tripuraneni KR. Stepping beyond Counts in Recovery of Total Knee Arthroplasty: A Prospective Study on Passively Collected Gait Metrics. Sensors (Basel). 2023 Jun 14;23(12):5588. doi: 10.3390/s23125588.
PubMed 37420754Fary C, Cholewa J, Abshagen S, Van Andel D, Ren A, Anderson MB, Tripuraneni K. Stepping Beyond Counts in Recovery of Total Hip Arthroplasty: A Prospective Study on Passively Collected Gait Metrics. Sensors (Basel). 2023 Jul 20;23(14):6538. doi: 10.3390/s23146538.
PubMed 37514832Sato EH, Stevenson KL, Blackburn BE, Peters CL, Archibeck MJ, Pelt CE, Gililland JM, Anderson LA. Impact of Demographic Variables on Recovery After Total Hip Arthroplasty. J Arthroplasty. 2024 Mar;39(3):721-726. doi: 10.1016/j.arth.2023.09.012. Epub 2023 Sep 17.
PubMed 37717829DeMik DE, Lonner JH, Cholewa JM, Anderson MB, Kamath AF, Tripuraneni KR. Association Between Digitally Provided Education and 90-Day Return to Sexual Activity Following Total Knee Arthroplasty: A Randomized Controlled Trial. J Arthroplasty. 2024 Apr;39(4):916-920. doi: 10.1016/j.arth.2023.10.014. Epub 2023 Oct 16.
PubMed 37852452Fary C, Cholewa J, Ren AN, Abshagen S, Anderson MB, Tripuraneni K. Multicenter, prospective cohort study: immediate postoperative gains in active range of motion following robotic-assisted total knee replacement compared to a propensity-matched control using manual instrumentation. Arthroplasty. 2023 Dec 4;5(1):62. doi: 10.1186/s42836-023-00216-0.
PubMed 38044446Redfern RE, Crawford DA, Lombardi AV Jr, Tripuraneni KR, Van Andel DC, Anderson MB, Cholewa JM. Outcomes Vary by Pre-Operative Physical Activity Levels in Total Knee Arthroplasty Patients. J Clin Med. 2023 Dec 25;13(1):125. doi: 10.3390/jcm13010125.
PubMed 38202132Miller MD, Redfern RE, Anderson MB, Abshagen S, Van Andel D, Lonner JH. Completion of Patient-Reported Outcome Measures Improved With Use of a Mobile Application in Arthroplasty Patients: Results From a Randomized Controlled Trial. J Arthroplasty. 2024 Jul;39(7):1656-1662. doi: 10.1016/j.arth.2024.01.007. Epub 2024 Jan 10.
PubMed 38211730Pasqualini I, Huffman N, Redfern RE; Digital Health in Arthroplasty Writing Committee; Piuzzi NS. Despite Greater Improvement in Pain and Function Among Obese Patients Shortly After Total Knee Arthroplasty, There is No Difference in Patient-Reported Outcomes and Satisfaction Between Body Mass Index Classes at 1 Year Postoperatively. J Arthroplasty. 2024 Jul;39(7):1719-1725.e1. doi: 10.1016/j.arth.2024.01.043. Epub 2024 Feb 2.
PubMed 38309635
Study at a glance
From the registry record, last updated by the sponsor on 23 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Prospective Multicenter Longitudinal Cohort Study of the Mymobility Platform
- ClinicalTrials.gov ID
- NCT03737149
- Acronym / sponsor ID
- CLU2018-13CH
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip
- Keywords
- Knee Replacement, Knee Arthroplasty, Hip Replacement, Hip Arthroplasty, Joint Replacement, Physical Therapy, Partial Knee Replacement, Hip Pain, Chronic
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 6,559 participants (actual)
- Lead sponsor
- Zimmer BiometIndustry (pharma, biotech, devices)
- Study start
- 22 Oct 2018 (actual)
- Primary completion
- 15 Apr 2025 (actual)
- Study completion
- 15 Apr 2025 (actual)
- First posted
- 9 Nov 2018 (actual)
- Results
- Posted 23 Mar 2026
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Post-market prospective, multi-center longitudinal study to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a viable (and potentially improved) alternative to current standard of care physical therapy for hip and knee arthroplasty.
Detailed description
This is a post-market prospective, multi-center longitudinal study in subjects undergoing primary total knee arthroplasty (TKA), total hip arthroplasty (THA), or partial knee arthroplasty (PKA). The study objective is to determine if mobile application-guided education and exercise paired with accurate and sensitive activity monitoring, captured from consumer wearables, can provide a viable (and potentially improved) alternative to current standard of care patient education and physical therapy for hip and knee arthroplasty. The study will be conducted in phases. The first phase (N = 300) will consist of a pilot cohort of subjects and will primarily serve to determine site study staffing needs and time required for various elements of study execution. The second phase (N = 1,000, RCT) will consist of a randomized controlled subject cohort and will compare outcomes of mobile application-guided exercises and activity with standard of care (SOC) physical therapy. The third phase (N ~ 10,000 including subjects from both Phase I and the study arm from RCT/Phase II) will seek to collect enough data to enable the creation of decision support algorithms for outcomes of joint replacement. All subjects will undergo a TKA, THA, or PKA using SOC procedures and commercially-available devices as part of their clinical care. Subjects will then complete prescribed post-operative activities, such as physical therapy, according to SOC or performing exercises as scheduled through the mymobility app. In office assessments will be conducted at approximately 30 days prior to surgery, 30 days after surgery, and 3 months after surgery. Virtual assessments (including subject questionnaires and recording of adverse events) will occur at approximately 6 months and 1 year post-op.
February 2022 update: Eligibility criteria for new patients includes total knee and partial knee arthroplasty surgeries. Previously enrolled total hip arthroplasty patients will remain in the study for follow-up.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- This is a staged cohort study. In the first (pilot) cohort, all participating subjects will utilize the mymobility with Apple Watch platform. In the second (RCT) cohort, approximately 1,000 subjects will be randomized 1:1 to either the mymobility with Apple Watch platform or standard of care SOC. In the third (correlative analytics) cohort, all participating subjects will utilize the mymobility with Apple Watch platform.
| Arm | Type | Receives |
|---|---|---|
| mymobility with Apple Watch | Experimental | Other: mymobility with Apple WatchPost-operative mobile application-guided education and exercise paired with accurate and sensitive activity monitoring. |
| Standard of Care Physical Therapy | No intervention | –Standard of care patient education and post-operative physical therapy, as determined by local site guidelines and care pathways. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Subject must be 18 years of age or older.
- Subject qualifies for a primary, unilateral total or partial knee arthroplasty, based on physical exam and medical history.
- Investigator plans to treat subject with a commercially-available device, used on-label according to the manufacturer's instructions for use, as part of their clinical care.
- Subject owns and maintains an iPhone capable of pairing to the Apple Watch, supporting iOS updates and is compatible with the mymobility App.
- Subject is willing and able to complete the protocol required follow-up.
Key exclusion criteria (5 listed)
- Subject is a current alcohol or drug abuser as defined by the investigator.
- Subject is considered a member of a protected population (e.g., prisoner, mentally incompetent, etc.).
- Subject has systemic inflammatory arthropathies which would interfere or compromise the activity profiles within this study.
- Subject is currently participating in any other surgical intervention, physical therapy or pain management study which would compromise the results of this study.
- Subject requires simultaneous or staged bilateral replacements, staged<90 days apart. Subjects can be enrolled into the study for the second, staged arthroplasty if scheduled >89 days after their first, contralateral replacement.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| mymobility with Apple WatchThe mymobility mobile application is a mobile software platform designed to facilitate remote episode of care management and asynchronous communication between the provider care team and their patient via provider-approved care plans and engagement communications. Current care pathways have been developed for: Total Hip Replacement, Total Knee Replacement and Partial Knee Replacement. Designed for the orthopedic population, mymobility also integrates wearable data from the Apple Watch into provider dashboards, providing enhanced understanding and monitoring of patients throughout the episode of care. | Other | mymobility with Apple Watch |
Primary outcome
Phase II (RCT): Readmissions
Time frame: 30 Days
The number of subjects with a readmission within 30 days after knee or hip replacement surgery.
12 secondary outcomes
Phase II (RCT): Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS, JR)
Time frame: 90 Days
Phase II (RCT): Hip Disability and Osteoarthritis Outcome Score - Joint Replacement (HOOS, JR)
Time frame: 90 Days
Phase II RCT: EQ-5D-5L
Time frame: 90 Days
Phase II (RCT): Manipulation Under Anesthesia (MUA)
Time frame: 90 Days
Phase II (RCT): Timed Up and Go (TUG)
Time frame: 90 Days
Phase II (RCT): Single-Leg Stance (SLS) Test
Time frame: 90 Days
Phase II (RCT): Subject Satisfaction
Time frame: 90 Days
Phase II RCT: Urgent Care Center and Emergency Room Visits
Time frame: 90 Days
Phase I (Pilot): Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS, JR)
Time frame: 90 Days
Phase I (Pilot): Hip Disability and Osteoarthritis Outcome Score - Joint Replacement (HOOS, JR)
Time frame: 90 Days
Phase III (Correlative): Knee Injury and Osteoarthritis Outcome Score - Joint Replacement (KOOS, JR)
Time frame: 90 Days
Phase III (Correlative): Hip Disability and Osteoarthritis Outcome Score - Joint Replacement (HOOS, JR)
Time frame: 90 Days
Results and safety
Loading the posted results from ClinicalTrials.gov…
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Mar 2026.
- Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
- Results publication: PubMed 34053272Crawford DA, Duwelius PJ, Sneller MA, Morris MJ, Hurst JM, Berend KR, Lombardi AV. 2021 Mark Coventry Award: Use of a smartphone-based care platform after primary partial and total knee arthroplasty: a prospective randomized controlled trial. Bone Joint J. 2021 Jun;103-B(6 Supple A):3-12. doi: 10.1302/0301-620X.103B6.BJJ-2020-2352.R1.
- Results publication: PubMed 34192907Crawford DA, Lombardi AV Jr, Berend KR, Huddleston JI 3rd, Peters CL, DeHaan A, Zimmerman EK, Duwelius PJ. Early outcomes of primary total hip arthroplasty with use of a smartphone-based care platform: a prospective randomized controlled trial. Bone Joint J. 2021 Jul;103-B(7 Supple B):91-97. doi: 10.1302/0301-620X.103B7.BJJ-2020-2402.R1.
- Results publication: PubMed 34462184Tripuraneni KR, Foran JRH, Munson NR, Racca NE, Carothers JT. A Smartwatch Paired With A Mobile Application Provides Postoperative Self-Directed Rehabilitation Without Compromising Total Knee Arthroplasty Outcomes: A Randomized Controlled Trial. J Arthroplasty. 2021 Dec;36(12):3888-3893. doi: 10.1016/j.arth.2021.08.007. Epub 2021 Aug 9.
- Results publication: PubMed 36889524Alexander JS, Redfern RE, Duwelius PJ, Berend KR, Lombardi AV Jr, Crawford DA. Use of a Smartphone-Based Care Platform After Primary Partial and Total Knee Arthroplasty: 1-Year Follow-Up of a Prospective Randomized Controlled Trial. J Arthroplasty. 2023 Jul;38(7 Suppl 2):S208-S214. doi: 10.1016/j.arth.2023.02.082. Epub 2023 Mar 6.
- Results publication: PubMed 36996947Christensen JC, Blackburn BE, Anderson LA, Gililland JM, Peters CL, Archibeck MJ, Pelt CE. Recovery Curve for Patient Reported Outcomes and Objective Physical Activity After Primary Total Knee Arthroplasty-A Multicenter Study Using Wearable Technology. J Arthroplasty. 2023 Jun;38(6S):S94-S102. doi: 10.1016/j.arth.2023.03.060. Epub 2023 Mar 28.
- Results publication: PubMed 37068568Sato EH, Stevenson KL, Blackburn BE, Peters CL, Archibeck MJ, Pelt CE, Gililland JM, Anderson LA. Recovery Curves for Patient Reported Outcomes and Physical Function After Total Hip Arthroplasty. J Arthroplasty. 2023 Jul;38(7S):S65-S71. doi: 10.1016/j.arth.2023.04.012. Epub 2023 Apr 15.
- Results publication: PubMed 37088222Booth MW, Riegler V, King JS, Barrack RL, Hannon CP. Patients' Perceptions of Remote Monitoring and App-Based Rehabilitation Programs: A Comparison of Total Hip and Knee Arthroplasty. J Arthroplasty. 2023 Jul;38(7S):S39-S43. doi: 10.1016/j.arth.2023.04.032. Epub 2023 Apr 23.
- Results publication: PubMed 37420754Fary C, Cholewa J, Abshagen S, Van Andel D, Ren A, Anderson MB, Tripuraneni KR. Stepping beyond Counts in Recovery of Total Knee Arthroplasty: A Prospective Study on Passively Collected Gait Metrics. Sensors (Basel). 2023 Jun 14;23(12):5588. doi: 10.3390/s23125588.
- Results publication: PubMed 37514832Fary C, Cholewa J, Abshagen S, Van Andel D, Ren A, Anderson MB, Tripuraneni K. Stepping Beyond Counts in Recovery of Total Hip Arthroplasty: A Prospective Study on Passively Collected Gait Metrics. Sensors (Basel). 2023 Jul 20;23(14):6538. doi: 10.3390/s23146538.
- Results publication: PubMed 37717829Sato EH, Stevenson KL, Blackburn BE, Peters CL, Archibeck MJ, Pelt CE, Gililland JM, Anderson LA. Impact of Demographic Variables on Recovery After Total Hip Arthroplasty. J Arthroplasty. 2024 Mar;39(3):721-726. doi: 10.1016/j.arth.2023.09.012. Epub 2023 Sep 17.
- Results publication: PubMed 37852452DeMik DE, Lonner JH, Cholewa JM, Anderson MB, Kamath AF, Tripuraneni KR. Association Between Digitally Provided Education and 90-Day Return to Sexual Activity Following Total Knee Arthroplasty: A Randomized Controlled Trial. J Arthroplasty. 2024 Apr;39(4):916-920. doi: 10.1016/j.arth.2023.10.014. Epub 2023 Oct 16.
- Results publication: PubMed 38044446Fary C, Cholewa J, Ren AN, Abshagen S, Anderson MB, Tripuraneni K. Multicenter, prospective cohort study: immediate postoperative gains in active range of motion following robotic-assisted total knee replacement compared to a propensity-matched control using manual instrumentation. Arthroplasty. 2023 Dec 4;5(1):62. doi: 10.1186/s42836-023-00216-0.
- Individual participant dataSharing planned: No
Related trials for Osteoarthritis, Knee
Recruiting
Aquatic Exercise in Patients With Knee Osteoarthritis
Central Sensitization, Knee Osteoarthristis
Active, not recruiting
14022 ATTUNE Cementless RP Clinical Performance Evaluation
Osteoarthritis
Not yet recruiting
Patient Satisfaction After Robotic-Assisted Versus Conventional Total Knee Arthroplasty
Osteoarthritis (Knee), Robotic Assisted Arthroplasty
Active, not recruiting
Study to Evaluate the Safety and Effectiveness of the REAL INTELLIGENCE™ CORI™ in Total Knee Arthroplasty (TKA) Procedure
Arthroplasty, Replacement
Active, not recruiting
Comparative Effect of Dual Task Training and Rhythmic Stabilization in Knee Osteoarthritis Patients
Knee Osteoarthritis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Hillary Overholser study director
Zimmer Biomet
30 sites in 4 countries: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing mymobility with Apple Watch in people with Osteoarthritis, Knee and Osteoarthritis, Hip, run by Zimmer Biomet at 30 sites in 4 countries.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 30 sites in United States, Australia, Italy, Netherlands. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Yes. Results are posted in the registry (first posted 23 Mar 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Phase II (RCT): Readmissions (time frame: 30 Days). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT03737149, which also lists 37 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Mar 2026.