Relationship, MaritalNCT04378309
Illinois United ePREP Program Evaluation
A study testing ePREP in people with Relationship, Marital and Relational Problems, run by University of Illinois at Urbana-Champaign at 1 site in United States.
Trial summary
The current research is designed to implement and evaluate the ePREP relationship intervention with couples throughout the state of Illinois. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Relationship, Marital, Relational Problems
- What is being tested?
- ePREP
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 338 participants
- Where
- 1 siteUnited States
- Study dates
- 15 Oct 2020to 30 Jun 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Resident of Illinois
- Married, engaged, or living with their partner for at least 6 months
- Both partners willing to participate in online relationship-focused programming
Who cannot join
- One or both partners reports severe forms of intimate partner violence occurring in the relationship
Trial locations and contacts
1 site in 1 country.
United States1 site
University of Illinois Extension
Urbana, Illinois, 61820
About this study
Official title: Illinois United: ePREP Program Evaluation
The current research is designed to implement and evaluate the ePREP relationship intervention with couples throughout the state of Illinois.
Read the detailed description
The objective of the research is to evaluate the effectiveness of an online intervention for help-seeking couples designed to promote individual and couple well-being. Within the United States, one-third of married couples are distressed and almost half of first marriages end in divorce/separation. Relationship distress is associated with a variety of negative health outcomes, including worsened mental and physical health problems in partners as well as internalizing and externalizing problems in children. Newly developed online intervention programs for distressed couples have shown to be efficacious, but their overall reach to the general population remains limited. The current research is designed to implement and evaluate the ePREP relationship intervention with couples throughout the state of Illinois.
- Conditions
- Relationship, Marital, Relational Problems
- Being tested
- ePREP
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ePREPBehavioural
6-session online psychoeducational program with supporting coach calls
| Study group | Role | What they receive |
|---|---|---|
| ePrep | Experimental | The ePREP program is the online version of the Prevention and Relationship Enhancement Program. It consists of 6 self-directed online sessions and accompanying homework and brief coach calls. Receives: Behavioral: ePREP |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Relationship Satisfaction
Couple Satisfaction Index
Measured: Immediate and 6-month follow-up
Change in Relationship Instability
3 item Relationship Instability measure (from Doss et al., 2020, Journal of Consulting and Clinical Psychology)
Measured: Immediate and 6-month follow-up
Change in Partner Support
5 item Partner Support measure (from Doss et al., 2020, Journal of Consulting and Clinical Psychology)
Measured: Immediate and 6-month follow-up
Change in Communication conflict
4 item communication conflict measure (from Doss et al., 2020, Journal of Consulting and Clinical Psychology)
Measured: Immediate and 6-month follow-up
Change in Relationship confidence
4 item relationship confidence measure (from Stanley et al., 1994)
Measured: Immediate and 6-month follow-up
Change in Intervention-target behavior
PREP 3 keys (new measure created for this study, assessing participants confidence in implementing each of the 3 keys of the PREP program)
Measured: Immediate and 6-month follow-up
Secondary outcomes (8)
Change in Partner Aggression
7 item partner aggression (from Doss et al., 2020, Journal of Consulting and Clinical Psychology)
Measured: Immediate and 6-month follow-up
Change in Psychological distress
Kessler 6 item psychological distress
Measured: Immediate and 6-month follow-up
Change in Anger
NIH PROMIS 5 item anger measure
Measured: Immediate and 6-month follow-up
Change in Perceived Stress
Cohen's 10 item perceived stress measure
Measured: Immediate and 6-month follow-up
Change in General Health
SF-36 4 item general health perceptions
Measured: Immediate and 6-month follow-up
Change in Insomnia
7 item insomnia severity index
Measured: Immediate and 6-month follow-up
Change in Problematic Alcohol Use
PROMIS 7 item problematic alcohol use
Measured: Immediate and 6-month follow-up
Change in Exercise
1 item exercise (CDC BRFSS 2016 adaptation)
Measured: Immediate and 6-month follow-up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 May 2020
- Study start15 Oct 2020
- Primary completion10 Nov 2022
- Study completion30 Jun 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Relationship, MaritalStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 338 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Illinois at Urbana-Champaign
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Allen Barton, University of Illinois at Urbana-Champaign
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04378309
- Sponsor's protocol ID
- 20837
- Status last verified
- Aug 2025
- First submitted
- 1 May 2020
- Last updated
- 24 Aug 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 24 Aug 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Illinois United: ePREP Program Evaluation
- ClinicalTrials.gov ID
- NCT04378309
- Acronym / sponsor ID
- 20837
- Conditions
- Relationship, Marital, Relational Problems
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 338 participants (actual)
- Lead sponsor
- University of Illinois at Urbana-ChampaignUniversity, hospital or other
- Study start
- 15 Oct 2020 (actual)
- Primary completion
- 10 Nov 2022 (actual)
- Study completion
- 30 Jun 2023 (actual)
- First posted
- 7 May 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The current research is designed to implement and evaluate the ePREP relationship intervention with couples throughout the state of Illinois.
Detailed description
The objective of the research is to evaluate the effectiveness of an online intervention for help-seeking couples designed to promote individual and couple well-being. Within the United States, one-third of married couples are distressed and almost half of first marriages end in divorce/separation. Relationship distress is associated with a variety of negative health outcomes, including worsened mental and physical health problems in partners as well as internalizing and externalizing problems in children. Newly developed online intervention programs for distressed couples have shown to be efficacious, but their overall reach to the general population remains limited. The current research is designed to implement and evaluate the ePREP relationship intervention with couples throughout the state of Illinois.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| ePrep | Experimental | Behavioral: ePREPThe ePREP program is the online version of the Prevention and Relationship Enhancement Program. It consists of 6 self-directed online sessions and accompanying homework and brief coach calls. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Resident of Illinois
- Married, engaged, or living with their partner for at least 6 months
- Both partners willing to participate in online relationship-focused programming
Key exclusion criteria (1 listed)
- One or both partners reports severe forms of intimate partner violence occurring in the relationship
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ePREP6-session online psychoeducational program with supporting coach calls | Behavioural | ePrep |
Primary outcome
Change in Relationship Satisfaction
Time frame: Immediate and 6-month follow-up
Couple Satisfaction Index
Change in Relationship Instability
Time frame: Immediate and 6-month follow-up
3 item Relationship Instability measure (from Doss et al., 2020, Journal of Consulting and Clinical Psychology)
Change in Partner Support
Time frame: Immediate and 6-month follow-up
5 item Partner Support measure (from Doss et al., 2020, Journal of Consulting and Clinical Psychology)
Change in Communication conflict
Time frame: Immediate and 6-month follow-up
4 item communication conflict measure (from Doss et al., 2020, Journal of Consulting and Clinical Psychology)
Change in Relationship confidence
Time frame: Immediate and 6-month follow-up
4 item relationship confidence measure (from Stanley et al., 1994)
Change in Intervention-target behavior
Time frame: Immediate and 6-month follow-up
PREP 3 keys (new measure created for this study, assessing participants confidence in implementing each of the 3 keys of the PREP program)
8 secondary outcomes
Change in Partner Aggression
Time frame: Immediate and 6-month follow-up
Change in Psychological distress
Time frame: Immediate and 6-month follow-up
Change in Anger
Time frame: Immediate and 6-month follow-up
Change in Perceived Stress
Time frame: Immediate and 6-month follow-up
Change in General Health
Time frame: Immediate and 6-month follow-up
Change in Insomnia
Time frame: Immediate and 6-month follow-up
Change in Problematic Alcohol Use
Time frame: Immediate and 6-month follow-up
Change in Exercise
Time frame: Immediate and 6-month follow-up
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Aug 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ePREP in people with Relationship, Marital and Relational Problems, run by University of Illinois at Urbana-Champaign at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Aug 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Relationship Satisfaction (time frame: Immediate and 6-month follow-up). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Aug 2025.