Asthma AttackIMPAXNCT04410120
Impact of Asthma Exacerbations
An observational study of Asthma Attack, run by University of Nottingham at 1 site in United Kingdom.
Trial summary
The purpose of the study is to gain a deeper understanding of the impact of asthma attacks on the lives of patients who experience them. This will help us to describe the true extent of the impact of asthma attacks on factors of importance to patients which have not previously been well described, including the… Read more about this study
- Who is it for?
- Ages 16 years and older
- Conditions the study is for
- Asthma Attack
- What is being tested?
- Interview
- How many people
- 30 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- Sep 2020to Sep 2020
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 16 years and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Adults with previous clinician diagnosis of asthma who have had a recent (≤4 weeks) asthma attack for which they received ≥3 days of systemic corticosteroid treatment
Who may be able to join
- Adults with previous clinician diagnosis of asthma (16 years and above)
- Recent (≤4 weeks) asthma attack for which patient received ≥3 days of systemic corticosteroid treatment
Who cannot join
- Anyone under the age of 16 years.
- Anyone unable to speak or understand English.
Trial locations and contacts
1 site in 1 country.
United Kingdom1 site
Nottingham Respiratory Research Unit
Nottingham, Nottinghamshire, NG5 1PB
Matthew J Martin, PhD, MBChB, matthew.martin@nottingham.ac.uk
Matthew J Martin, PhD, MBChB
About this study
Official title: Impact of Asthma Exacerbations: A Qualitative Study
The purpose of the study is to gain a deeper understanding of the impact of asthma attacks on the lives of patients who experience them. This will help us to describe the true extent of the impact of asthma attacks on factors of importance to patients which have not previously been well described, including the psychological, social, financial and emotional burden of asthma attacks.
Additionally, it is hoped that detailed questioning regarding features of asthma attacks from a patient perspective will improve our understanding of patient recognition of attacks, consistency of certain features of attacks and patient views regarding preventative strategies for attacks. Patient experiences of asthma attacks are poorly described in previous research. Hence this work is expected to provide useful insights into these experiences which will contribute to improvements in detecting, treating and preventing asthma attacks.
The study will consist of a one-off interview lasting about 45 minutes with patients who have recently had asthma attacks. We plan to recruit patients for the study from an outpatient clinic for those who have had a recent attack or from a register of patients who have volunteered for future asthma research studies. The interviews will take place in person at the Respiratory Research Unit at the Nottingham City Hospital or over the telephone depending on patient preference.
- Conditions
- Asthma Attack
- Being tested
- Interview
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
InterviewOther
Semi-structured 45 minute interviews regarding impact of asthma attacks
| Study group | Role | What they receive |
|---|---|---|
| Asthma with recent (<4/52) asthma attack | Not described Receives: Other: Interview |
What is being measured
The primary outcome is the main question the study is designed to answer.
Thematic analysis of interview transcripts using framework approach
Thematic analysis of interview transcripts using framework approach
Measured: One off 45 minute interview
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jun 2020
- Study startSep 2020 (estimated)
- Primary completionSep 2020 (estimated)
- Study completionSep 2020 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Asthma AttackStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Nottingham
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04410120
- Sponsor's protocol ID
- 20038
- Acronym
- IMPAX
- Status last verified
- May 2020
- First submitted
- 26 May 2020
- Last updated
- 1 Jun 2020
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Pradhan A, Jayes L, Bains M, Martin MJ. Patient experience, understanding and self-management of asthma attacks: a qualitative study. J Asthma. 2025 May;62(5):872-880. doi: 10.1080/02770903.2024.2449230. Epub 2025 Jan 10.
PubMed 39773014
Study at a glance
From the registry record, last updated by the sponsor on 1 Jun 2020. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Asthma Exacerbations: A Qualitative Study
- ClinicalTrials.gov ID
- NCT04410120
- Acronym / sponsor ID
- IMPAX / 20038
- Conditions
- Asthma Attack
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- University of NottinghamUniversity, hospital or other
- Study start
- Sep 2020 (estimated)
- Primary completion
- Sep 2020 (estimated)
- Study completion
- Sep 2020 (estimated)
- First posted
- 1 Jun 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the study is to gain a deeper understanding of the impact of asthma attacks on the lives of patients who experience them. This will help us to describe the true extent of the impact of asthma attacks on factors of importance to patients which have not previously been well described, including the psychological, social, financial and emotional burden of asthma attacks.
Additionally, it is hoped that detailed questioning regarding features of asthma attacks from a patient perspective will improve our understanding of patient recognition of attacks, consistency of certain features of attacks and patient views regarding preventative strategies for attacks. Patient experiences of asthma attacks are poorly described in previous research. Hence this work is expected to provide useful insights into these experiences which will contribute to improvements in detecting, treating and preventing asthma attacks.
The study will consist of a one-off interview lasting about 45 minutes with patients who have recently had asthma attacks. We plan to recruit patients for the study from an outpatient clinic for those who have had a recent attack or from a register of patients who have volunteered for future asthma research studies. The interviews will take place in person at the Respiratory Research Unit at the Nottingham City Hospital or over the telephone depending on patient preference.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Asthma with recent (<4/52) asthma attack | – | Other: Interview |
Who may qualify
- Ages
- 16 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Adults with previous clinician diagnosis of asthma who have had a recent (≤4 weeks) asthma attack for which they received ≥3 days of systemic corticosteroid treatment
Key inclusion criteria (2 listed)
- Adults with previous clinician diagnosis of asthma (16 years and above)
- Recent (≤4 weeks) asthma attack for which patient received ≥3 days of systemic corticosteroid treatment
Key exclusion criteria (2 listed)
- Anyone under the age of 16 years.
- Anyone unable to speak or understand English.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| InterviewSemi-structured 45 minute interviews regarding impact of asthma attacks | Other | Asthma with recent (<4/52) asthma attack |
Primary outcome
Thematic analysis of interview transcripts using framework approach
Time frame: One off 45 minute interview
Thematic analysis of interview transcripts using framework approach
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Jun 2020.
- Derived from this study: PubMed 39773014Pradhan A, Jayes L, Bains M, Martin MJ. Patient experience, understanding and self-management of asthma attacks: a qualitative study. J Asthma. 2025 May;62(5):872-880. doi: 10.1080/02770903.2024.2449230. Epub 2025 Jan 10.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Asthma Attack, run by University of Nottingham at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 1 Jun 2020. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Thematic analysis of interview transcripts using framework approach (time frame: One off 45 minute interview). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT04410120, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Jun 2020.